IL139960A0 - Macrocylic analogs and methods of their use and preparation - Google Patents

Macrocylic analogs and methods of their use and preparation

Info

Publication number
IL139960A0
IL139960A0 IL13996099A IL13996099A IL139960A0 IL 139960 A0 IL139960 A0 IL 139960A0 IL 13996099 A IL13996099 A IL 13996099A IL 13996099 A IL13996099 A IL 13996099A IL 139960 A0 IL139960 A0 IL 139960A0
Authority
IL
Israel
Prior art keywords
preparation
analogs
macrocylic
methods
useful
Prior art date
Application number
IL13996099A
Other languages
English (en)
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22219026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL139960(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of IL139960A0 publication Critical patent/IL139960A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL13996099A 1998-06-17 1999-06-16 Macrocylic analogs and methods of their use and preparation IL139960A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8968298P 1998-06-17 1998-06-17
PCT/US1999/013677 WO1999065894A1 (en) 1998-06-17 1999-06-16 Macrocyclic analogs and methods of their use and preparation

Publications (1)

Publication Number Publication Date
IL139960A0 true IL139960A0 (en) 2002-02-10

Family

ID=22219026

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13996099A IL139960A0 (en) 1998-06-17 1999-06-16 Macrocylic analogs and methods of their use and preparation

Country Status (23)

Country Link
US (4) US6214865B1 (ru)
EP (4) EP1087960B1 (ru)
JP (1) JP4454151B2 (ru)
KR (1) KR100798600B1 (ru)
CN (1) CN1216051C (ru)
AT (1) ATE502932T1 (ru)
AU (1) AU762998B2 (ru)
BE (1) BE2011C028I2 (ru)
BR (1) BRPI9911326B8 (ru)
CA (3) CA2632433C (ru)
CY (2) CY1111516T1 (ru)
DE (2) DE69943296D1 (ru)
DK (1) DK1087960T3 (ru)
FR (1) FR11C0038I2 (ru)
HK (1) HK1035534A1 (ru)
HU (1) HU227912B1 (ru)
IL (1) IL139960A0 (ru)
LU (1) LU91854I2 (ru)
NO (5) NO328280B1 (ru)
NZ (1) NZ508597A (ru)
PT (1) PT1087960E (ru)
WO (1) WO1999065894A1 (ru)
ZA (1) ZA200007159B (ru)

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WO2003072754A2 (en) * 2002-02-27 2003-09-04 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Conjugates of ligand, linker and cytotoxic agent and related compositions and methods of use
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CN104311571B (zh) * 2007-10-03 2019-07-02 卫材R&D管理有限公司 用于合成软海绵素b类似物的中间体和方法
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RU2476216C1 (ru) * 2009-03-30 2013-02-27 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Липосомальная композиция
JP5622719B2 (ja) 2009-03-30 2014-11-12 エーザイ・アール・アンド・ディー・マネジメント株式会社 リポソーム組成物の製造方法
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CN104053645A (zh) 2011-11-30 2014-09-17 阿方拉研究股份有限公司 用于制备(3r)-2,4-二-离去基团-3-甲基丁-1-烯的工艺
JP2015501818A (ja) 2011-12-16 2015-01-19 アルフォラ リサーチ インコーポレイテッドAlphora Research Inc. 3−((2s,5s)−4−メチレン−5−(3−オキソプロピル)テトラヒドロフラン−2−イル)プロパノール誘導体およびそれらの有用な中間体を調製する方法
CN104080793B (zh) * 2011-12-29 2017-09-19 阿方拉研究股份有限公司 2‑((2s,3s,4r,5r)‑5‑((s)‑3‑氨基‑2‑羟基丙‑1‑基)‑4‑甲氧基‑3‑(苯磺酰甲基)四氢呋喃‑2‑基)乙醛衍生物以及它们的制备方法
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JP6511613B2 (ja) * 2013-07-03 2019-05-15 サンド・アクチエンゲゼルシヤフト ハリコンドリンBの大環状C1−ケト類似体の製造のための合成方法及び該方法に有用な中間体、例えば−SO2−(p−トリル)基を含有する中間体
CN103483352A (zh) * 2013-10-18 2014-01-01 李友香 抗肿瘤的药用原料药
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WO2017188350A1 (ja) 2016-04-28 2017-11-02 エーザイ・アール・アンド・ディー・マネジメント株式会社 腫瘍の成長を抑制する方法
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EP3587408A1 (en) 2004-06-03 2020-01-01 Eisai R&D Management Co., Ltd. Intermediates for the preparation of halichondrin b
CN104311571B (zh) 2007-10-03 2019-07-02 卫材R&D管理有限公司 用于合成软海绵素b类似物的中间体和方法
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Also Published As

Publication number Publication date
DK1087960T3 (da) 2011-06-14
EP2277873B1 (en) 2012-05-30
EP2272840A1 (en) 2011-01-12
CN1216051C (zh) 2005-08-24
NO2011018I1 (no) 2011-09-26
RU2245335C2 (ru) 2005-01-27
US6469182B1 (en) 2002-10-22
CA2335300A1 (en) 1999-12-23
HU227912B1 (en) 2012-05-29
CA2632433A1 (en) 1999-12-23
EP2277873A1 (en) 2011-01-26
HK1035534A1 (en) 2001-11-30
NO2022019I1 (no) 2022-06-03
EP2272839B1 (en) 2012-08-22
CY1111516T1 (el) 2014-04-09
NO20093217L (no) 2001-02-15
US6214865B1 (en) 2001-04-10
CA2755266C (en) 2014-08-12
KR20010083050A (ko) 2001-08-31
ATE502932T1 (de) 2011-04-15
DE122011100031I1 (de) 2011-12-15
WO1999065894A1 (en) 1999-12-23
BE2011C028I2 (en) 2018-08-24
NZ508597A (en) 2004-01-30
US8148554B2 (en) 2012-04-03
CY2011010I1 (el) 2014-04-09
BR9911326A (pt) 2001-04-03
NO2011026I2 (no) 2012-06-11
CA2335300C (en) 2008-10-07
NO20006316D0 (no) 2000-12-12
BR9911326B1 (pt) 2015-01-06
JP2002518384A (ja) 2002-06-25
HUP0103357A3 (en) 2002-10-28
FR11C0038I1 (fr) 2011-10-14
DE69943296D1 (de) 2011-05-05
NO2011026I1 (no) 2012-01-09
HUP0103357A2 (hu) 2002-01-28
EP1087960A1 (en) 2001-04-04
EP1087960B1 (en) 2011-03-23
EP1087960A4 (en) 2004-12-01
US6365759B1 (en) 2002-04-02
NO331183B1 (no) 2011-10-24
CA2632433C (en) 2012-02-07
CN1312804A (zh) 2001-09-12
JP4454151B2 (ja) 2010-04-21
FR11C0038I2 (fr) 2013-01-11
CA2755266A1 (en) 1999-12-23
EP2272839A1 (en) 2011-01-12
EP2272840B1 (en) 2012-08-22
LU91854I2 (fr) 2011-10-17
AU762998C (en) 2000-01-05
BRPI9911326B8 (pt) 2021-05-25
AU4573999A (en) 2000-01-05
ZA200007159B (en) 2001-12-04
KR100798600B1 (ko) 2008-01-28
NO328280B1 (no) 2010-01-25
US20110172446A1 (en) 2011-07-14
NO20006316L (no) 2001-02-15
PT1087960E (pt) 2011-06-17
AU762998B2 (en) 2003-07-10
CY2011010I2 (el) 2014-04-09

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