SG10201602147YA - Methods And Compositions For Predicting Response To Eribulin - Google Patents

Methods And Compositions For Predicting Response To Eribulin

Info

Publication number
SG10201602147YA
SG10201602147YA SG10201602147YA SG10201602147YA SG10201602147YA SG 10201602147Y A SG10201602147Y A SG 10201602147YA SG 10201602147Y A SG10201602147Y A SG 10201602147YA SG 10201602147Y A SG10201602147Y A SG 10201602147YA SG 10201602147Y A SG10201602147Y A SG 10201602147YA
Authority
SG
Singapore
Prior art keywords
eribulin
compositions
methods
predicting response
predicting
Prior art date
Application number
SG10201602147YA
Inventor
Sergei I Agoulnik
Michael Chapman Byrne
Bruce A Littlefield
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of SG10201602147YA publication Critical patent/SG10201602147YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
SG10201602147YA 2011-03-18 2012-03-16 Methods And Compositions For Predicting Response To Eribulin SG10201602147YA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161454426P 2011-03-18 2011-03-18

Publications (1)

Publication Number Publication Date
SG10201602147YA true SG10201602147YA (en) 2016-05-30

Family

ID=45879070

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201602147YA SG10201602147YA (en) 2011-03-18 2012-03-16 Methods And Compositions For Predicting Response To Eribulin
SG2013069646A SG193489A1 (en) 2011-03-18 2012-03-16 Methods and compositions for predicting response to eribulin

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2013069646A SG193489A1 (en) 2011-03-18 2012-03-16 Methods and compositions for predicting response to eribulin

Country Status (8)

Country Link
US (1) US9637795B2 (en)
EP (1) EP2686441B1 (en)
JP (3) JP2014509515A (en)
CN (1) CN103562406B (en)
CA (1) CA2828959A1 (en)
ES (1) ES2731653T3 (en)
SG (2) SG10201602147YA (en)
WO (1) WO2012129100A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2928464A1 (en) * 2012-12-04 2015-10-14 Eisai R&D Management Co., Ltd. Use of eribulin in the treatment of breast cancer
US9549922B2 (en) 2013-06-26 2017-01-24 Eisai R&D Management Co., Ltd. Use of eribulin and lenvatinib as combination therapy for treatment of cancer
KR20170039096A (en) * 2014-05-28 2017-04-10 에자이 알앤드디 매니지먼트 가부시키가이샤 Use of eribulin in the treatment of cancer
EP3148336B1 (en) 2014-05-28 2019-10-02 Eisai R&D Management Co., Ltd. Eribulin and poly (adp ribose) polymerase (parp) inhibitors as combination therapy for the treatment of cancer
JP6951248B2 (en) 2015-03-04 2021-10-20 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. Combination of PD-1 antagonist and eribulin to treat cancer
EP4053278A1 (en) 2015-05-01 2022-09-07 Japan Science and Technology Agency Anti-tumor agent suppressing or inhibiting zic5
KR102445255B1 (en) 2016-03-02 2022-09-22 에자이 알앤드디 매니지먼트 가부시키가이샤 Eribulin-Based Antibody-Drug Conjugates and Methods of Use
WO2019097073A1 (en) 2017-11-20 2019-05-23 Basilea Pharmaceutica International AG Pharmaceutical combinations for use in the treatment of neoplastic diseases
WO2020179712A1 (en) * 2019-03-01 2020-09-10 Eisai R&D Management Co., Ltd. Methods for predicting tumor response to eribulin
US11083705B2 (en) 2019-07-26 2021-08-10 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
CN113174427B (en) * 2021-04-29 2023-02-28 遵义医科大学 Method for detecting ERGIC3 mRNA based on DNA molecule
CN113512733B (en) * 2021-05-13 2022-07-26 浙江工业大学 Method for synthesizing eribulin intermediate through electrochemical NHK reaction

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US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5075216A (en) 1988-09-23 1991-12-24 Cetus Corporation Methods for dna sequencing with thermus aquaticus dna polymerase
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
DE69233331T3 (en) 1991-11-22 2007-08-30 Affymetrix, Inc., Santa Clara Combinatorial Polymersynthesis Strategies
US5547835A (en) 1993-01-07 1996-08-20 Sequenom, Inc. DNA sequencing by mass spectrometry
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US5545531A (en) 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
EP0880598A4 (en) 1996-01-23 2005-02-23 Affymetrix Inc Nucleic acid analysis techniques
ATE291097T1 (en) 1997-10-31 2005-04-15 Affymetrix Inc A Delaware Corp EXPRESSION PROFILES IN ADULT AND FETAL ORGANS
US6020135A (en) 1998-03-27 2000-02-01 Affymetrix, Inc. P53-regulated genes
US8097648B2 (en) 1998-06-17 2012-01-17 Eisai R&D Management Co., Ltd. Methods and compositions for use in treating cancer
US6653341B1 (en) 1998-06-17 2003-11-25 Eisai Co., Ltd. Methods and compositions for use in treating cancer
AU762998B2 (en) 1998-06-17 2003-07-10 Eisai R&D Management Co., Ltd. Macrocyclic analogs and methods of their use and preparation
US20050208512A1 (en) * 2003-10-01 2005-09-22 The Ohio State University Research Foundation Determining the chemosensitivity of cells to cytotoxic agents
US20060154312A1 (en) * 2004-12-09 2006-07-13 Sergei Agoulnik Tubulin isotype screening in cancer therapy using halichondrin B analogs
WO2011109637A1 (en) * 2010-03-03 2011-09-09 Koo Foundation Sun Yat-Sen Cancer Center Methods for classifying and treating breast cancers

Also Published As

Publication number Publication date
JP2019150027A (en) 2019-09-12
CN103562406B (en) 2018-03-27
US20140235707A1 (en) 2014-08-21
JP6612280B2 (en) 2019-11-27
SG193489A1 (en) 2013-10-30
CN103562406A (en) 2014-02-05
JP2017148049A (en) 2017-08-31
EP2686441B1 (en) 2019-05-08
US9637795B2 (en) 2017-05-02
WO2012129100A1 (en) 2012-09-27
CA2828959A1 (en) 2012-09-27
JP2014509515A (en) 2014-04-21
EP2686441A1 (en) 2014-01-22
ES2731653T3 (en) 2019-11-18

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