IL100449A - N-acylated-1-(4-aminophenyl)-7,8-methylenedioxy-5H-2,3-benzodiazepine derivatives their preparation and pharmaceutical compositions containing them - Google Patents

N-acylated-1-(4-aminophenyl)-7,8-methylenedioxy-5H-2,3-benzodiazepine derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number
IL100449A
IL100449A IL10044991A IL10044991A IL100449A IL 100449 A IL100449 A IL 100449A IL 10044991 A IL10044991 A IL 10044991A IL 10044991 A IL10044991 A IL 10044991A IL 100449 A IL100449 A IL 100449A
Authority
IL
Israel
Prior art keywords
group
general formula
benzodiazepine
hydrogen
methyl
Prior art date
Application number
IL10044991A
Other languages
English (en)
Other versions
IL100449A0 (en
Original Assignee
Gyogyszerkutato Intezet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyogyszerkutato Intezet filed Critical Gyogyszerkutato Intezet
Publication of IL100449A0 publication Critical patent/IL100449A0/xx
Publication of IL100449A publication Critical patent/IL100449A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
IL10044991A 1990-12-21 1991-12-20 N-acylated-1-(4-aminophenyl)-7,8-methylenedioxy-5H-2,3-benzodiazepine derivatives their preparation and pharmaceutical compositions containing them IL100449A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU398/90A HU219778B (hu) 1990-12-21 1990-12-21 Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
US08/080,604 US5459137A (en) 1990-12-21 1993-06-21 N-acyl-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for preparing same

Publications (2)

Publication Number Publication Date
IL100449A0 IL100449A0 (en) 1992-09-06
IL100449A true IL100449A (en) 1995-12-31

Family

ID=26317922

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10044991A IL100449A (en) 1990-12-21 1991-12-20 N-acylated-1-(4-aminophenyl)-7,8-methylenedioxy-5H-2,3-benzodiazepine derivatives their preparation and pharmaceutical compositions containing them

Country Status (25)

Country Link
US (3) US5459137A (es)
EP (1) EP0492485B1 (es)
JP (1) JP2756742B2 (es)
KR (1) KR0169134B1 (es)
CN (2) CN1041420C (es)
AT (1) ATE160350T1 (es)
AU (1) AU641578B2 (es)
BR (1) BR9105517A (es)
CA (1) CA2057504C (es)
CZ (1) CZ280769B6 (es)
DE (1) DE69128236T2 (es)
DK (1) DK0492485T3 (es)
ES (1) ES2112848T3 (es)
FI (1) FI102611B1 (es)
GR (1) GR3026127T3 (es)
HR (1) HRP920677B1 (es)
HU (1) HU219778B (es)
IE (1) IE914518A1 (es)
IL (1) IL100449A (es)
MX (1) MX9102734A (es)
NO (1) NO300376B1 (es)
NZ (1) NZ241110A (es)
RU (1) RU2102387C1 (es)
SI (1) SI9111966B (es)
ZA (1) ZA9110064B (es)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639751A (en) * 1990-12-21 1997-06-17 Cyogyszerkutato Intezet Kft N-acyl-2,3-benzodiazepine derivatives for treating acute and chronic neurodegenerative disorders
HU219778B (hu) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
US5519019A (en) * 1990-12-21 1996-05-21 Gyogyszerkutato Intezet N-acyl-2,3-benzoidazepine derivatives, pharmaceutical compositions containing them and process for preparing same
US5521174A (en) * 1990-12-21 1996-05-28 Gyogyszerkutato Intezet Kv. N-acyl-2,3-benzodiazepine derivatives and a method of treating spasms of the skeletal musculature therewith
HU219777B (hu) * 1993-07-02 2001-07-30 Gyógyszerkutató Intézet Kft. Optikailag aktív 1-(4-nitro-fenil)-4-metil-7,8-metiléndioxi-3,4-dihidro-5H-2,3-benzodiazepin és eljárás előállítására
DE4428835A1 (de) * 1994-08-01 1996-02-08 Schering Ag Neue 3-substituierte 3H-2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
US5665878A (en) 1994-08-31 1997-09-09 Eli Lilly And Company Stereoselective process for producing dihydro-2,3-benzodiazepine derivatives
TR199501072A2 (tr) 1994-08-31 1996-06-21 Lilly Co Eli Dihidro-2,3-benzodiazepin türevinin fiziksel bicimi.
EP1157992B1 (en) * 1994-08-31 2005-08-24 Eli Lilly And Company Dihydro-2,3-Benzodiazepine derivatives
TR199501070A2 (tr) 1994-08-31 1996-06-21 Lilly Co Eli Dihidro-2,3-benzodiazepin türevinin kristalli bicimi.
TR199501071A2 (tr) * 1994-08-31 1996-06-21 Lilly Co Eli Dihidro-2,3-benzodiazepin türevlerinin üretilmesi icin stereoselektif islem.
US5670640A (en) * 1996-02-02 1997-09-23 Hoffmann-La Roche Inc. Process for the manufacture of imidazodiazepine derivatives
US5891871A (en) * 1996-03-21 1999-04-06 Cocensys, Inc. Substituted 2,3-benzodiazepin-4-ones and the use thereof
ZA972746B (en) * 1996-04-04 1998-10-09 Egyt Gyogyszervegyeszeti Gyar Novel 2,3-benzodiazepine derivatives
HU9600871D0 (en) * 1996-04-04 1996-05-28 Gyogyszerkutato Intezet New 2,3-benzodiazepine derivatives
HUP9701325A1 (hu) 1997-07-31 2000-08-28 Gyógyszerkutató Intézet Kft. Új 2,3-benzodiazepin-származékok
UA67749C2 (uk) * 1997-08-12 2004-07-15 Егіш Дьйодьсердьяр Рт. Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
KR20010022856A (ko) * 1997-08-12 2001-03-26 사바 키스 ; 아틸라 만디 야노스 템페 ; 기울라 시미그 Ａｍｐａ/카이네이트 수용체 억제제로서의 1,3-디옥솔로/4,5-ｈ//2,3/벤조디아제핀 유도체
EP1100504A2 (en) * 1998-07-02 2001-05-23 Eisai Co., Ltd. Pharmaceutical compositions and their uses for treatment of demyelinating disorders
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
US6720081B2 (en) 1999-12-22 2004-04-13 Schott Spezialglas Gmbh UV-reflective interference layer system
EP1296960A2 (en) * 2000-06-16 2003-04-02 Annovis, Inc. 5h-2,3-benzodiazepine antagonists of excitatory amino acid receptors
HU225100B1 (hu) * 2000-12-21 2006-06-28 Egyt Gyogyszervegyeszeti Gyar 2,3-Benzodiazepinszármazékok, ilyen hatóanyagot tartalmazó gyógyászati készítmények és alkalmazásuk
US6649607B2 (en) 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US7745431B2 (en) 2002-12-03 2010-06-29 Vela Acquisition Corporation Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5H-2,3-benzodiazepine and uses thereof
WO2004069155A2 (en) * 2002-12-03 2004-08-19 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine and uses therof
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
US6858605B2 (en) * 2003-02-04 2005-02-22 Ivax Drug Research Institute, Ltd. Substituted 2,3-benzodiazepine derivatives
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
CA2526478A1 (en) 2003-05-21 2004-12-02 Alexza Pharmaceuticals, Inc. Methods of controlling uniformity of substrate temperature and self-contained heating unit and drug-supply unit employing same
WO2005007106A2 (en) * 2003-07-10 2005-01-27 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a non-nmda glutamate modulator for the treatment of central nervous system damage
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
AU2004322756B2 (en) 2004-08-12 2011-04-14 Alexza Pharmaceuticals, Inc. Aerosol drug delivery device incorporating percussively activated heat packages
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
AU2006334172A1 (en) * 2005-12-30 2007-07-12 Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag Optical isomers of dihydro-2,3-benzodiazepines and their stereoselective synthesis
US20080108622A1 (en) * 2006-10-19 2008-05-08 Eisenach James C Combination therapy for the treatment of pain
US20080108603A1 (en) * 2006-10-19 2008-05-08 Eisenach James C Combination therapy for the treatment of pain
ES2594867T3 (es) 2007-03-09 2016-12-23 Alexza Pharmaceuticals, Inc. Unidad de calentamiento para usar en un dispositivo de administración de fármaco
TW200902024A (en) * 2007-04-02 2009-01-16 Teva Pharma Novel 2,3-benzodiazepine derivatives and their use as antipsychotic agents
MX2020007997A (es) 2018-02-02 2020-12-03 Alexza Pharmaceuticals Inc Dispositivo electrico de aerosol de condensacion.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2353187A1 (de) * 1973-05-02 1974-11-14 Kali Chemie Ag Neue benzodiazepinderivate
US4164740A (en) * 1976-03-04 1979-08-14 Constant James N Synthetic aperture using image scanner
HU186760B (en) * 1981-03-12 1985-09-30 Gyogyszerkutato Intezet Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives
HU191702B (en) * 1984-06-27 1987-03-30 Gyogyszerkutato Intezet New process for preparing 1-aryl-5 h-2,3-benzodiazepines
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines
HU195788B (en) * 1986-05-21 1988-07-28 Gyogyszerkutato Intezet Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them
HU198494B (en) * 1986-08-15 1989-10-30 Gyogyszerkutato Intezet Process for producing new 3,4-dihydro-5h-2,3-benzodiazepine derivative and acid addition salts thereof, as well as pharmaceutical compositions comprising same
HU219778B (hu) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények

Also Published As

Publication number Publication date
NO915060D0 (no) 1991-12-20
HRP920677B1 (en) 2000-02-29
US5459137A (en) 1995-10-17
CN1062730A (zh) 1992-07-15
JP2756742B2 (ja) 1998-05-25
CZ280769B6 (cs) 1996-04-17
FI102611B (fi) 1999-01-15
US5604223A (en) 1997-02-18
FI916032A0 (fi) 1991-12-20
IL100449A0 (en) 1992-09-06
CA2057504A1 (en) 1992-06-22
DK0492485T3 (da) 1998-07-27
RU2102387C1 (ru) 1998-01-20
GR3026127T3 (en) 1998-05-29
IE914518A1 (en) 1992-07-01
DE69128236D1 (de) 1998-01-02
US5536832A (en) 1996-07-16
SI9111966A (sl) 1998-04-30
DE69128236T2 (de) 1998-05-14
HU908398D0 (en) 1991-07-29
ES2112848T3 (es) 1998-04-16
ZA9110064B (en) 1992-10-28
CA2057504C (en) 2002-02-12
EP0492485B1 (en) 1997-11-19
FI102611B1 (fi) 1999-01-15
HU219778B (hu) 2001-07-30
CN1191111A (zh) 1998-08-26
NO915060L (no) 1992-06-22
KR920012086A (ko) 1992-07-25
HUT59684A (en) 1992-06-29
NZ241110A (en) 1994-04-27
SI9111966B (en) 2001-04-30
AU8996391A (en) 1992-06-25
ATE160350T1 (de) 1997-12-15
CN1041420C (zh) 1998-12-30
FI916032A7 (fi) 1992-06-22
AU641578B2 (en) 1993-09-23
JPH0570463A (ja) 1993-03-23
EP0492485A1 (en) 1992-07-01
CN1135982C (zh) 2004-01-28
MX9102734A (es) 1992-06-01
KR0169134B1 (ko) 1999-01-15
CZ398591A3 (en) 1994-01-19
BR9105517A (pt) 1992-09-01
NO300376B1 (no) 1997-05-20
HRP920677A2 (en) 1994-08-31

Similar Documents

Publication Publication Date Title
EP0492485B1 (en) N-Acyl-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for preparing same
FI66604B (fi) Foerfarande foer framstaellning av nya 5h-2,3-bensodiazepinderivat med inverkan pao det centrala nervsystemet
US5519019A (en) N-acyl-2,3-benzoidazepine derivatives, pharmaceutical compositions containing them and process for preparing same
EP0328000B1 (de) Indolocarbazol-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
RU2040524C1 (ru) Производные хиназолин- или бензодиазепинкарбоновой кислоты и их соли
GB2116179A (en) 1,2,4-triazine and pyrazine derivatives
GB2071095A (en) Heterocyclic compounds processes for their preparation and pharmaceutical compositions containing them
US5639751A (en) N-acyl-2,3-benzodiazepine derivatives for treating acute and chronic neurodegenerative disorders
US5521174A (en) N-acyl-2,3-benzodiazepine derivatives and a method of treating spasms of the skeletal musculature therewith
HU206719B (en) Process for producing 1-/4-acylamino-phenyl/-7,8-methylenedioxy-5h-2,3-benzodiazepine derivatives, acid addicional salts and pharmaceutical compositions containing them
EP1003749B1 (en) 8-SUBSTITUTED-9H-1,3-DIOXOLO/4,5-h/2,3/BENZODIAZEPINE DERIVATES, AS AMPA/KAINATERECEPTOR INHIBITORS
HU194824B (en) Process for production of new derivatives of bi-24-pirroli/di/n-dion and medical preparatives containing them
SU1169538A3 (ru) Способ получени трициклических соединений
EP0089322B1 (en) Tricyclic derivatives of 5,6-dihydro-11h-dibenzo(b,e)azepin-6-one having pharmacological avtivity, and method for their preparation
DE69516100T2 (de) Trizyklische Oximether, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US4983603A (en) Tricyclic cholinergic receptor agonists
WO1997019934A1 (en) Quinoxaline compounds, pharmaceutical preparations containing them and a process for the preparation thereof
SU1468902A1 (ru) Способ получени пирано @ 3,4-в @ индолов
JP4420606B2 (ja) ６−アリール−４Ｈ−ｓ−トリアゾロ［３，４−ｃ］−チエノ［２，３−ｅ］−１，４−ジアゼピンの調製方法
AT395155B (de) Verfahren zur herstellung von neuen imidazo(1,5-a)(1,4)diazepinverbindungen
CS195707B2 (en) Method of producing novel n up 4-substituted derivatives of 1,3,4,5-tetrahydro-2h-1,4-benzodiazepine-2-one
FI74004C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara piperazinylpyrido/2,3-b/- och -/3,4-b/ pyrazinderivat.
JP3749275B2 (ja) オキサゼピノピリドインドール誘導体及びその製造方法
JPS634545B2 (es)
CS196644B1 (cs) 2-substituční deriváty ergolinu — I

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired