IE913582A1 - Cyclopeptides - Google Patents

Cyclopeptides

Info

Publication number
IE913582A1
IE913582A1 IE358291A IE358291A IE913582A1 IE 913582 A1 IE913582 A1 IE 913582A1 IE 358291 A IE358291 A IE 358291A IE 358291 A IE358291 A IE 358291A IE 913582 A1 IE913582 A1 IE 913582A1
Authority
IE
Ireland
Prior art keywords
arg
phe
ile
gly
ala
Prior art date
Application number
IE358291A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19904032271 external-priority patent/DE4032271A1/de
Priority claimed from DE19904032268 external-priority patent/DE4032268A1/de
Priority claimed from DE19904032269 external-priority patent/DE4032269A1/de
Priority claimed from DE19914117733 external-priority patent/DE4117733A1/de
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of IE913582A1 publication Critical patent/IE913582A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C07K14/582—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
IE358291A 1990-10-11 1991-10-16 Cyclopeptides IE913582A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19904032271 DE4032271A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19904032268 DE4032268A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19904032269 DE4032269A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19914117733 DE4117733A1 (de) 1991-05-30 1991-05-30 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
IE913582A1 true IE913582A1 (en) 1992-04-22

Family

ID=27435038

Family Applications (1)

Application Number Title Priority Date Filing Date
IE358291A IE913582A1 (en) 1990-10-11 1991-10-16 Cyclopeptides

Country Status (12)

Country Link
EP (1) EP0552238A1 (de)
JP (1) JPH06501950A (de)
KR (1) KR930702395A (de)
AU (1) AU8736691A (de)
CA (1) CA2089747A1 (de)
CZ (1) CZ61893A3 (de)
FI (1) FI931499A0 (de)
HU (1) HUT63859A (de)
IE (1) IE913582A1 (de)
PL (1) PL168456B1 (de)
SK (1) SK32693A3 (de)
WO (1) WO1992006998A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665704A (en) * 1993-11-12 1997-09-09 Genentech, Inc. Receptor specific atrial natriuretic peptides
US5846932A (en) * 1993-11-12 1998-12-08 Genentech, Inc. Receptor specific atrial natriuretic peptides
US6525022B1 (en) 1993-11-12 2003-02-25 Genentech, Inc. Receptor specific atrial natriuretic peptides
WO1999067286A2 (en) * 1998-06-24 1999-12-29 The Rockefeller University Novel staphylococcus peptides for bacterial interference
US6337385B1 (en) 1998-06-24 2002-01-08 The Rockefeller University Staphylococcus peptides for bacterial interference
FR2797689B1 (fr) * 1999-08-16 2003-06-27 Pasteur Sanofi Diagnostics Utilisation de composes synthetiques pour des immunodosages
US6455587B1 (en) * 2000-03-15 2002-09-24 Pharmacor Inc. Amino acid derivatives as HIV aspartyl protease inhibitors
US7388008B2 (en) 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
AU2006319716B2 (en) 2005-11-30 2012-02-02 Taimed Biologics, Inc. Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation
DK2001518T3 (da) 2006-03-30 2013-10-07 Palatin Technologies Inc Cykliske natriuretiske peptidfremstillinger
US8580746B2 (en) 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
US7795221B2 (en) 2006-03-30 2010-09-14 Palatin Technologies, Inc. Linear natriuretic peptide constructs
JP5401652B2 (ja) 2006-09-21 2014-01-29 タイメッド バイオロジクス インコーポレイテッド プロテアーゼ阻害剤
PT2118123E (pt) 2007-01-31 2016-02-10 Harvard College Péptidos de p53 estabilizados e suas utilizações
WO2008121767A2 (en) 2007-03-28 2008-10-09 President And Fellows Of Harvard College Stitched polypeptides
RU2582678C2 (ru) 2010-08-13 2016-04-27 Эйлерон Терапьютикс, Инк. Пептидомиметические макроциклы
TWI643868B (zh) 2011-10-18 2018-12-11 艾利倫治療公司 擬肽巨環化合物
JP6450191B2 (ja) 2012-02-15 2019-01-09 エイルロン セラピューティクス，インコーポレイテッド ペプチドミメティック大環状化合物
EP2819688A4 (de) 2012-02-15 2015-10-28 Aileron Therapeutics Inc Triazol- und thioethervernetzte peptidomimetische makrozyklen
WO2014071241A1 (en) 2012-11-01 2014-05-08 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
WO2015179438A1 (en) * 2014-05-20 2015-11-26 Ohio State Innovation Foundation Small molecule rac or rho inhibitors
KR102570210B1 (ko) 2014-09-24 2023-08-23 에일러론 테라퓨틱스 인코포레이티드 펩티드모방 거대고리 및 이의 제제
KR20170058424A (ko) 2014-09-24 2017-05-26 에일러론 테라퓨틱스 인코포레이티드 펩티드모방 거대고리 및 이의 용도
JP2018516844A (ja) 2015-03-20 2018-06-28 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ペプチド模倣大環状分子およびその使用
US10023613B2 (en) 2015-09-10 2018-07-17 Aileron Therapeutics, Inc. Peptidomimetic macrocycles as modulators of MCL-1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337891C (en) * 1987-12-16 1996-01-02 John Dimaio Anf derivatives with novel bridging
US4935492A (en) * 1987-12-24 1990-06-19 California Biotechnology Inc. Cyclic analogs of atrial natriuretic peptides
DK380288D0 (da) * 1988-07-07 1988-07-07 Novo Industri As Hidtil ukendet peptider

Also Published As

Publication number Publication date
HUT63859A (en) 1993-10-28
WO1992006998A1 (de) 1992-04-30
FI931499A (fi) 1993-04-02
HU9301054D0 (en) 1993-07-28
PL168456B1 (pl) 1996-02-29
KR930702395A (ko) 1993-09-09
JPH06501950A (ja) 1994-03-03
CZ61893A3 (en) 1994-01-19
SK32693A3 (en) 1993-09-09
AU8736691A (en) 1992-05-20
EP0552238A1 (de) 1993-07-28
CA2089747A1 (en) 1992-04-12
FI931499A0 (fi) 1993-04-02

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Legal Events

Date Code Title Description
FC9A Application refused sect. 31(1)