HUT63859A - Process for producing cyclopeptides and pharmaceutical compositions comprising same - Google Patents

Process for producing cyclopeptides and pharmaceutical compositions comprising same

Info

Publication number
HUT63859A
HUT63859A HU931054A HU105493A HUT63859A HU T63859 A HUT63859 A HU T63859A HU 931054 A HU931054 A HU 931054A HU 105493 A HU105493 A HU 105493A HU T63859 A HUT63859 A HU T63859A
Authority
HU
Hungary
Prior art keywords
cyclopeptides
producing
same
pharmaceutical compositions
pharmaceutical
Prior art date
Application number
HU931054A
Other languages
Hungarian (hu)
Other versions
HU9301054D0 (en
Inventor
Gerd Schnorrenberg
Rainer Palluk
Stefan Heinrichs
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19904032271 external-priority patent/DE4032271A1/en
Priority claimed from DE19904032268 external-priority patent/DE4032268A1/en
Priority claimed from DE19904032269 external-priority patent/DE4032269A1/en
Priority claimed from DE19914117733 external-priority patent/DE4117733A1/en
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of HU9301054D0 publication Critical patent/HU9301054D0/en
Publication of HUT63859A publication Critical patent/HUT63859A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C07K14/582—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HU931054A 1990-10-11 1991-10-10 Process for producing cyclopeptides and pharmaceutical compositions comprising same HUT63859A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19904032271 DE4032271A1 (en) 1990-10-11 1990-10-11 New cyclo:peptide(s) are atrial natriuretic factor agonists - useful as hypotensives, vasodilators, spasmolytics and broncholytics, and as ligands in receptor binding assays
DE19904032268 DE4032268A1 (en) 1990-10-11 1990-10-11 New cyclo-peptide(s) are atrial natriuretic factor agonists - useful as hypotensives, vasodilators, spasmolytics and broncholytics, as ligands in receptor binding tests and for antibody purification
DE19904032269 DE4032269A1 (en) 1990-10-11 1990-10-11 New cyclo:peptide(s) are atrial natriuretic factor agonists - useful as hypotensives, vasodilators, spasmolytics and broncholytics, as ligands in receptor binding assays and for purificn. of antibodies
DE19914117733 DE4117733A1 (en) 1991-05-30 1991-05-30 Cyclo-peptide(s) agonists to atrial natriuretic protein

Publications (2)

Publication Number Publication Date
HU9301054D0 HU9301054D0 (en) 1993-07-28
HUT63859A true HUT63859A (en) 1993-10-28

Family

ID=27435038

Family Applications (1)

Application Number Title Priority Date Filing Date
HU931054A HUT63859A (en) 1990-10-11 1991-10-10 Process for producing cyclopeptides and pharmaceutical compositions comprising same

Country Status (12)

Country Link
EP (1) EP0552238A1 (en)
JP (1) JPH06501950A (en)
KR (1) KR930702395A (en)
AU (1) AU8736691A (en)
CA (1) CA2089747A1 (en)
CZ (1) CZ61893A3 (en)
FI (1) FI931499A0 (en)
HU (1) HUT63859A (en)
IE (1) IE913582A1 (en)
PL (1) PL168456B1 (en)
SK (1) SK32693A3 (en)
WO (1) WO1992006998A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665704A (en) * 1993-11-12 1997-09-09 Genentech, Inc. Receptor specific atrial natriuretic peptides
US5846932A (en) * 1993-11-12 1998-12-08 Genentech, Inc. Receptor specific atrial natriuretic peptides
US6525022B1 (en) 1993-11-12 2003-02-25 Genentech, Inc. Receptor specific atrial natriuretic peptides
US6337385B1 (en) 1998-06-24 2002-01-08 The Rockefeller University Staphylococcus peptides for bacterial interference
CA2331888A1 (en) * 1998-06-24 1999-12-29 The Rockefeller University Novel staphylococcus peptides for bacterial interference
FR2797689B1 (en) * 1999-08-16 2003-06-27 Pasteur Sanofi Diagnostics USE OF SYNTHETIC COMPOUNDS FOR IMMUNODAYS
US6455587B1 (en) * 2000-03-15 2002-09-24 Pharmacor Inc. Amino acid derivatives as HIV aspartyl protease inhibitors
US7388008B2 (en) 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
ES2452718T3 (en) 2005-11-30 2014-04-02 Taimed Biologics, Inc. Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation
US8580746B2 (en) 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
DK2001518T3 (en) 2006-03-30 2013-10-07 Palatin Technologies Inc Cyclic natriuretic peptide preparations
US7795221B2 (en) 2006-03-30 2010-09-14 Palatin Technologies, Inc. Linear natriuretic peptide constructs
US8410300B2 (en) 2006-09-21 2013-04-02 Taimed Biologics, Inc. Protease inhibitors
CA2939778C (en) 2007-01-31 2019-01-29 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
EP2508531B1 (en) 2007-03-28 2016-10-19 President and Fellows of Harvard College Stitched polypeptides
JP2013535514A (en) 2010-08-13 2013-09-12 エイルロン セラピューティクス，インコーポレイテッド Peptidomimetic macrocycle
MX358886B (en) 2011-10-18 2018-08-31 Aileron Therapeutics Inc Peptidomimetic macrocyles.
CN108912211A (en) 2012-02-15 2018-11-30 爱勒让治疗公司 Triazole crosslinking and thioether crosslinking peptidomimetic macrocyclic compound
BR112014020103A2 (en) 2012-02-15 2018-10-09 Aileron Therapeutics, Inc. peptidomimetic macrocycles
BR112015009470A2 (en) 2012-11-01 2019-12-17 Aileron Therapeutics Inc disubstituted amino acids and their methods of preparation and use
US20170112896A1 (en) * 2014-05-20 2017-04-27 Ohio State Innovation Foundation Small molecule rac or rho inhibitors
US10905739B2 (en) 2014-09-24 2021-02-02 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and formulations thereof
WO2016049359A1 (en) 2014-09-24 2016-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
CA2979847A1 (en) 2015-03-20 2016-09-29 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
JP2018528217A (en) 2015-09-10 2018-09-27 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． Peptidomimetic macrocycles as modulators of MCL-1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337891C (en) * 1987-12-16 1996-01-02 John Dimaio Anf derivatives with novel bridging
US4935492A (en) * 1987-12-24 1990-06-19 California Biotechnology Inc. Cyclic analogs of atrial natriuretic peptides
DK380288D0 (en) * 1988-07-07 1988-07-07 Novo Industri As HOW TO UNKNOWN PEPTIDES

Also Published As

Publication number Publication date
CA2089747A1 (en) 1992-04-12
FI931499A (en) 1993-04-02
WO1992006998A1 (en) 1992-04-30
JPH06501950A (en) 1994-03-03
CZ61893A3 (en) 1994-01-19
AU8736691A (en) 1992-05-20
PL168456B1 (en) 1996-02-29
KR930702395A (en) 1993-09-09
FI931499A0 (en) 1993-04-02
HU9301054D0 (en) 1993-07-28
SK32693A3 (en) 1993-09-09
IE913582A1 (en) 1992-04-22
EP0552238A1 (en) 1993-07-28

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Legal Events

Date Code Title Description
DFA9 Temporary prot. cancelled due to abandonment