HUT63859A - Process for producing cyclopeptides and pharmaceutical compositions comprising same - Google Patents

Process for producing cyclopeptides and pharmaceutical compositions comprising same

Info

Publication number
HUT63859A
HUT63859A HU931054A HU105493A HUT63859A HU T63859 A HUT63859 A HU T63859A HU 931054 A HU931054 A HU 931054A HU 105493 A HU105493 A HU 105493A HU T63859 A HUT63859 A HU T63859A
Authority
HU
Hungary
Prior art keywords
cyclopeptides
producing
same
pharmaceutical compositions
pharmaceutical
Prior art date
Application number
HU931054A
Other languages
English (en)
Hungarian (hu)
Other versions
HU9301054D0 (en
Inventor
Gerd Schnorrenberg
Rainer Palluk
Stefan Heinrichs
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19904032268 external-priority patent/DE4032268A1/de
Priority claimed from DE19904032271 external-priority patent/DE4032271A1/de
Priority claimed from DE19904032269 external-priority patent/DE4032269A1/de
Priority claimed from DE19914117733 external-priority patent/DE4117733A1/de
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of HU9301054D0 publication Critical patent/HU9301054D0/hu
Publication of HUT63859A publication Critical patent/HUT63859A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C07K14/582—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HU931054A 1990-10-11 1991-10-10 Process for producing cyclopeptides and pharmaceutical compositions comprising same HUT63859A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19904032268 DE4032268A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19904032271 DE4032271A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19904032269 DE4032269A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19914117733 DE4117733A1 (de) 1991-05-30 1991-05-30 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
HU9301054D0 HU9301054D0 (en) 1993-07-28
HUT63859A true HUT63859A (en) 1993-10-28

Family

ID=27435038

Family Applications (1)

Application Number Title Priority Date Filing Date
HU931054A HUT63859A (en) 1990-10-11 1991-10-10 Process for producing cyclopeptides and pharmaceutical compositions comprising same

Country Status (12)

Country Link
EP (1) EP0552238A1 (de)
JP (1) JPH06501950A (de)
KR (1) KR930702395A (de)
AU (1) AU8736691A (de)
CA (1) CA2089747A1 (de)
CZ (1) CZ61893A3 (de)
FI (1) FI931499A (de)
HU (1) HUT63859A (de)
IE (1) IE913582A1 (de)
PL (1) PL168456B1 (de)
SK (1) SK32693A3 (de)
WO (1) WO1992006998A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6525022B1 (en) 1993-11-12 2003-02-25 Genentech, Inc. Receptor specific atrial natriuretic peptides
US5846932A (en) * 1993-11-12 1998-12-08 Genentech, Inc. Receptor specific atrial natriuretic peptides
US5665704A (en) * 1993-11-12 1997-09-09 Genentech, Inc. Receptor specific atrial natriuretic peptides
EP1090034A2 (de) * 1998-06-24 2001-04-11 The Rockefeller University Neue peptide aus staphylococcus zur bakteriellen hemmung
US6337385B1 (en) 1998-06-24 2002-01-08 The Rockefeller University Staphylococcus peptides for bacterial interference
FR2797689B1 (fr) * 1999-08-16 2003-06-27 Pasteur Sanofi Diagnostics Utilisation de composes synthetiques pour des immunodosages
US6455587B1 (en) * 2000-03-15 2002-09-24 Pharmacor Inc. Amino acid derivatives as HIV aspartyl protease inhibitors
US7388008B2 (en) 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
CN101405293B (zh) 2005-11-30 2013-03-13 中裕新药股份有限公司 天冬氨酰基蛋白酶抑制剂基于赖氨酸的前体药物及其制备方法
US8580746B2 (en) 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
JP2009532385A (ja) 2006-03-30 2009-09-10 パラティン・テクノロジーズ・インコーポレーテッド 線状ナトリウム利尿ペプチド構築物
BRPI0709427A2 (pt) 2006-03-30 2011-07-12 Palatin Technologies Inc "construto cìclico, composição farmacêutica e uso de um composto
JP5401652B2 (ja) 2006-09-21 2014-01-29 タイメッド バイオロジクス インコーポレイテッド プロテアーゼ阻害剤
JP5649825B2 (ja) 2007-01-31 2015-01-07 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド 安定化させたｐ５３ペプチドおよびその使用法
ES2430067T3 (es) 2007-03-28 2013-11-18 President And Fellows Of Harvard College Polipéptidos cosidos
KR20170058446A (ko) 2010-08-13 2017-05-26 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
RU2639523C2 (ru) 2011-10-18 2017-12-21 Эйлерон Терапьютикс, Инк. Пептидомиметические макроциклы и их применение
CA2862038C (en) 2012-02-15 2021-05-25 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
CA2864120A1 (en) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
JP6526563B2 (ja) 2012-11-01 2019-06-05 エイルロン セラピューティクス，インコーポレイテッド 二置換アミノ酸ならびにその調製および使用の方法
WO2015179438A1 (en) * 2014-05-20 2015-11-26 Ohio State Innovation Foundation Small molecule rac or rho inhibitors
CA2961029A1 (en) 2014-09-24 2016-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and formulations thereof
MX2017003797A (es) 2014-09-24 2017-06-15 Aileron Therapeutics Inc Macrociclos peptidomimeticos y usos de los mismos.
CN107614003A (zh) 2015-03-20 2018-01-19 艾瑞朗医疗公司 拟肽大环化合物及其用途
US10023613B2 (en) 2015-09-10 2018-07-17 Aileron Therapeutics, Inc. Peptidomimetic macrocycles as modulators of MCL-1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337891C (en) * 1987-12-16 1996-01-02 John Dimaio Anf derivatives with novel bridging
US4935492A (en) * 1987-12-24 1990-06-19 California Biotechnology Inc. Cyclic analogs of atrial natriuretic peptides
DK380288D0 (da) * 1988-07-07 1988-07-07 Novo Industri As Hidtil ukendet peptider

Also Published As

Publication number Publication date
KR930702395A (ko) 1993-09-09
AU8736691A (en) 1992-05-20
PL168456B1 (pl) 1996-02-29
SK32693A3 (en) 1993-09-09
CZ61893A3 (en) 1994-01-19
WO1992006998A1 (de) 1992-04-30
IE913582A1 (en) 1992-04-22
EP0552238A1 (de) 1993-07-28
FI931499A0 (fi) 1993-04-02
HU9301054D0 (en) 1993-07-28
JPH06501950A (ja) 1994-03-03
FI931499A (fi) 1993-04-02
CA2089747A1 (en) 1992-04-12

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Legal Events

Date Code Title Description
DFA9 Temporary prot. cancelled due to abandonment