FI931499A - Cyklopeptider, foerfarande foer deras framstaellning och deras anvaendningsaosom laekemedel - Google Patents

Cyklopeptider, foerfarande foer deras framstaellning och deras anvaendningsaosom laekemedel Download PDF

Info

Publication number
FI931499A
FI931499A FI931499A FI931499A FI931499A FI 931499 A FI931499 A FI 931499A FI 931499 A FI931499 A FI 931499A FI 931499 A FI931499 A FI 931499A FI 931499 A FI931499 A FI 931499A
Authority
FI
Finland
Prior art keywords
deras
laekemedelel
cyclopeptider
anvaendningsaosom
foerfarande foer
Prior art date
Application number
FI931499A
Other languages
English (en)
Finnish (fi)
Other versions
FI931499A0 (fi
Inventor
Gerd Schnorrenberg
Rainer Palluk
Stefan Heinrichs
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19904032268 external-priority patent/DE4032268A1/de
Priority claimed from DE19904032269 external-priority patent/DE4032269A1/de
Priority claimed from DE19904032271 external-priority patent/DE4032271A1/de
Priority claimed from DE19914117733 external-priority patent/DE4117733A1/de
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of FI931499A publication Critical patent/FI931499A/fi
Publication of FI931499A0 publication Critical patent/FI931499A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/58Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C07K14/582Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin at least 1 amino acid in D-form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI931499A 1990-10-11 1993-04-02 Cyklopeptider, foerfarande foer deras framstaellning och deras anvaendningsaosom laekemedel FI931499A0 (fi)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19904032268 DE4032268A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19904032269 DE4032269A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19904032271 DE4032271A1 (de) 1990-10-11 1990-10-11 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE19914117733 DE4117733A1 (de) 1991-05-30 1991-05-30 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
PCT/EP1991/001934 WO1992006998A1 (de) 1990-10-11 1991-10-10 Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
FI931499A true FI931499A (fi) 1993-04-02
FI931499A0 FI931499A0 (fi) 1993-04-02

Family

ID=27435038

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931499A FI931499A0 (fi) 1990-10-11 1993-04-02 Cyklopeptider, foerfarande foer deras framstaellning och deras anvaendningsaosom laekemedel

Country Status (12)

Country Link
EP (1) EP0552238A1 (de)
JP (1) JPH06501950A (de)
KR (1) KR930702395A (de)
AU (1) AU8736691A (de)
CA (1) CA2089747A1 (de)
CZ (1) CZ61893A3 (de)
FI (1) FI931499A0 (de)
HU (1) HUT63859A (de)
IE (1) IE913582A1 (de)
PL (1) PL168456B1 (de)
SK (1) SK32693A3 (de)
WO (1) WO1992006998A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846932A (en) * 1993-11-12 1998-12-08 Genentech, Inc. Receptor specific atrial natriuretic peptides
US6525022B1 (en) 1993-11-12 2003-02-25 Genentech, Inc. Receptor specific atrial natriuretic peptides
US5665704A (en) * 1993-11-12 1997-09-09 Genentech, Inc. Receptor specific atrial natriuretic peptides
US6337385B1 (en) 1998-06-24 2002-01-08 The Rockefeller University Staphylococcus peptides for bacterial interference
AU769791B2 (en) * 1998-06-24 2004-02-05 New York University Novel Staphylococcus peptides for bacterial interference
FR2797689B1 (fr) * 1999-08-16 2003-06-27 Pasteur Sanofi Diagnostics Utilisation de composes synthetiques pour des immunodosages
US6455587B1 (en) * 2000-03-15 2002-09-24 Pharmacor Inc. Amino acid derivatives as HIV aspartyl protease inhibitors
US7388008B2 (en) 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
US8227450B2 (en) 2005-11-30 2012-07-24 Ambrilia Biopharma Inc. Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation
WO2007115175A2 (en) 2006-03-30 2007-10-11 Palatin Technologies, Inc. Cyclic natriuretic peptide constructs
US8580746B2 (en) 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
US7795221B2 (en) 2006-03-30 2010-09-14 Palatin Technologies, Inc. Linear natriuretic peptide constructs
US8410300B2 (en) 2006-09-21 2013-04-02 Taimed Biologics, Inc. Protease inhibitors
CA2677045C (en) 2007-01-31 2016-10-18 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
AU2008232709C1 (en) 2007-03-28 2015-01-15 President And Fellows Of Harvard College Stitched polypeptides
SI2603600T1 (sl) 2010-08-13 2019-04-30 Aileron Therapeutics, Inc. Peptidomimetični makrocikli
TWI643868B (zh) 2011-10-18 2018-12-11 艾利倫治療公司 擬肽巨環化合物
US8987414B2 (en) 2012-02-15 2015-03-24 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
KR102112373B1 (ko) 2012-02-15 2020-05-18 에일러론 테라퓨틱스 인코포레이티드 펩티드모방체 마크로사이클
AU2013337388B2 (en) 2012-11-01 2018-08-02 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
US20170112896A1 (en) * 2014-05-20 2017-04-27 Ohio State Innovation Foundation Small molecule rac or rho inhibitors
AU2015320545C1 (en) 2014-09-24 2020-05-14 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and formulations thereof
WO2016049359A1 (en) 2014-09-24 2016-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
MX2017011834A (es) 2015-03-20 2018-04-11 Aileron Therapeutics Inc Macrociclos peptidomimeticos y usos de los mismos.
JP2018528217A (ja) 2015-09-10 2018-09-27 エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. Mcl−1のモジュレーターとしてのペプチド模倣大環状分子

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337891C (en) * 1987-12-16 1996-01-02 John Dimaio Anf derivatives with novel bridging
US4935492A (en) * 1987-12-24 1990-06-19 California Biotechnology Inc. Cyclic analogs of atrial natriuretic peptides
DK380288D0 (da) * 1988-07-07 1988-07-07 Novo Industri As Hidtil ukendet peptider

Also Published As

Publication number Publication date
CZ61893A3 (en) 1994-01-19
PL168456B1 (pl) 1996-02-29
WO1992006998A1 (de) 1992-04-30
IE913582A1 (en) 1992-04-22
JPH06501950A (ja) 1994-03-03
HUT63859A (en) 1993-10-28
HU9301054D0 (en) 1993-07-28
KR930702395A (ko) 1993-09-09
EP0552238A1 (de) 1993-07-28
FI931499A0 (fi) 1993-04-02
SK32693A3 (en) 1993-09-09
CA2089747A1 (en) 1992-04-12
AU8736691A (en) 1992-05-20

Similar Documents

Publication Publication Date Title
FI925767A (fi) Dialkoxi-pyridinyl-bensimidazolderivater, foerfaranden foer deras framstaellning och deras farmaceutiska anvaendning
FI925766A (fi) Substituerade bensimidazoler, foerfarande foer deras framstaellning och deras farmaceutiska anvaendning
FI931499A (fi) Cyklopeptider, foerfarande foer deras framstaellning och deras anvaendningsaosom laekemedel
FI900494A (fi) Anordning foer ingaongs- och utgaongsluft och luftkonditioneringsfoerfarande.
FI934498A (fi) Vikbart foeremaol, saosom informationsbaerare, behaollare och motsvarande
FI931301A0 (fi) Foerpackning innehaollande saedeslag, noetter och frukter
FI904014A0 (fi) Fastklibbande materialer och deras framstaellning.
FI930380A (fi) Dynemicinanaloger: syntes, foerfarande foer framstaellning och anvaendning
FI902014A0 (fi) Foerfarande och anordning foer skjutoevning.
FI900479A (fi) Foerfarande och anordning foer predikterande kodning.
FI83361B (fi) Fogkonstruktion och foerstycke.
FI904373A0 (fi) Gasavskiljare foer vaetskor och suspensioner.
FI903825A0 (fi) Trappsteg och foerfarande foer tillverkning daerav.
FI901637A (fi) Andningsapparat foer giftgas och roekdykning.
FI904440A (fi) Saerskilt foer raffinoerer avsedd malskiva och motsvarande raffinoer.
FI901168A (fi) Hackelsemaskin och blaosmaskin foer bergvill.
FI904367A (fi) Kommuniceringsfoerfarande och media-apparat foer visuell kommunikation.
FI904241A0 (fi) Anordning foer byggnadsavfall och avfallscontainer.
FI904031A0 (fi) Hoernbalk och fogkonstruktion foer byggnad.
FI900480A (fi) Foerfarande och anordning foer predikterande kodning.
FI900327A0 (fi) Foerfarande och anordning foer tunnplaotformning.
FI903615A0 (fi) Borrningsfoerfarande och borrkroneapparatur.
FI903267A0 (fi) Elapparat och daerfoer avsett jordningsorgan.
FI902888A0 (fi) Enzymprodukt och foerfarande foer framstaellning daerav.
FI902786A0 (fi) Reparationsfoerpackning och tillaeggsreflex.

Legal Events

Date Code Title Description
FD Application lapsed