ID24730A - Senyawa-senyawa heterosiklik untuk penghambatan sekresi asam lambung, proses pembuatan dan komposisi-komposisi farmasinya - Google Patents

Senyawa-senyawa heterosiklik untuk penghambatan sekresi asam lambung, proses pembuatan dan komposisi-komposisi farmasinya

Info

Publication number
ID24730A
ID24730A IDW20000987A ID20000987A ID24730A ID 24730 A ID24730 A ID 24730A ID W20000987 A IDW20000987 A ID W20000987A ID 20000987 A ID20000987 A ID 20000987A ID 24730 A ID24730 A ID 24730A
Authority
ID
Indonesia
Prior art keywords
heterosiclic
balic
observation
compounds
manufacture process
Prior art date
Application number
IDW20000987A
Other languages
English (en)
Indonesian (id)
Inventor
Kosrat Amin
Mikael Dahlstrom
Peter Nordberg
Ingemar Starke
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ID24730A publication Critical patent/ID24730A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW20000987A 1997-11-28 1998-11-18 Senyawa-senyawa heterosiklik untuk penghambatan sekresi asam lambung, proses pembuatan dan komposisi-komposisi farmasinya ID24730A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9704404A SE9704404D0 (sv) 1997-11-28 1997-11-28 New compounds

Publications (1)

Publication Number Publication Date
ID24730A true ID24730A (id) 2000-08-03

Family

ID=20409181

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000987A ID24730A (id) 1997-11-28 1998-11-18 Senyawa-senyawa heterosiklik untuk penghambatan sekresi asam lambung, proses pembuatan dan komposisi-komposisi farmasinya

Country Status (32)

Country Link
US (1) US6518270B1 (cg-RX-API-DMAC7.html)
EP (1) EP1042324B1 (cg-RX-API-DMAC7.html)
JP (1) JP2001525322A (cg-RX-API-DMAC7.html)
KR (1) KR20010032559A (cg-RX-API-DMAC7.html)
CN (1) CN1142933C (cg-RX-API-DMAC7.html)
AR (1) AR016972A1 (cg-RX-API-DMAC7.html)
AT (1) ATE233263T1 (cg-RX-API-DMAC7.html)
AU (1) AU752187C (cg-RX-API-DMAC7.html)
BR (1) BR9814755A (cg-RX-API-DMAC7.html)
CA (1) CA2311798A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ292349B6 (cg-RX-API-DMAC7.html)
DE (1) DE69811735T2 (cg-RX-API-DMAC7.html)
DK (1) DK1042324T3 (cg-RX-API-DMAC7.html)
EE (1) EE04060B1 (cg-RX-API-DMAC7.html)
ES (1) ES2191356T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0100601A3 (cg-RX-API-DMAC7.html)
ID (1) ID24730A (cg-RX-API-DMAC7.html)
IL (1) IL136145A0 (cg-RX-API-DMAC7.html)
IS (1) IS5486A (cg-RX-API-DMAC7.html)
MY (1) MY121032A (cg-RX-API-DMAC7.html)
NO (1) NO315704B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ504355A (cg-RX-API-DMAC7.html)
PL (1) PL340920A1 (cg-RX-API-DMAC7.html)
PT (1) PT1042324E (cg-RX-API-DMAC7.html)
RU (1) RU2241000C2 (cg-RX-API-DMAC7.html)
SE (1) SE9704404D0 (cg-RX-API-DMAC7.html)
SK (1) SK283904B6 (cg-RX-API-DMAC7.html)
TR (1) TR200001530T2 (cg-RX-API-DMAC7.html)
TW (1) TW515798B (cg-RX-API-DMAC7.html)
UA (1) UA70932C2 (cg-RX-API-DMAC7.html)
WO (1) WO1999028322A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA9810468B (cg-RX-API-DMAC7.html)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0909323T3 (da) 1996-01-04 2007-05-21 Novartis Vaccines & Diagnostic Helicobacter pylori-bakterioferritin
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds
UY26380A1 (es) 1999-10-08 2001-04-30 Smithkline Beecham Corp Inhibidores de fab i
AU2002367773A1 (en) * 2001-04-06 2003-11-03 Affinium Pharmaceuticals, Inc. Fab i inhibitors
JP2003119140A (ja) * 2001-08-08 2003-04-23 Sankyo Co Ltd ピロロピリダジン化合物を含有する医薬
JP2005530739A (ja) * 2002-04-19 2005-10-13 セルラー ジェノミクス，インコーポレーテッド イミダゾ［１，２−ａ］ピラジン−８−イルアミン、生成方法、および使用方法
AU2003270489A1 (en) 2002-09-09 2004-03-29 Cellular Genomics, Inc. 6-ARYL-IMIDAZO(1,2-a)PYRAZIN-8-YLAMINES, METHOD OF MAKING, AND METHOD OF USE THEREOF
WO2004029057A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 内臓痛の治療または予防のための医薬組成物
WO2004029058A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 血中ガストリン濃度上昇の抑制のための医薬組成物
EP1575951B1 (en) 2002-12-06 2014-06-25 Debiopharm International SA Heterocyclic compounds, methods of making them and their use in therapy
US7160885B2 (en) 2003-02-10 2007-01-09 Cgi Pharmaceuticals, Inc. Certain 6, 8-(heteroaryl or aryl) disubstituted imidazo[1,2-a]pyrazines as modulators of Hsp90 complex activity
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
JP4880448B2 (ja) * 2003-03-17 2012-02-22 アフィナム ファーマシューティカルズ，インコーポレーテッド 複数の抗生物質を含む組成物、及びそれを用いる方法
WO2005014599A1 (en) 2003-06-04 2005-02-17 Cellular Genomics, Inc. Imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of bruton’s tyrosine kinase by such compounds
US7393848B2 (en) 2003-06-30 2008-07-01 Cgi Pharmaceuticals, Inc. Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds
WO2005019220A2 (en) 2003-08-11 2005-03-03 Cellular Genomics Inc. Substituted imidazo[1,2-a]pyrazines as modulators of kinase activity
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
KR101299399B1 (ko) * 2004-06-04 2013-08-22 아피늄 파마슈티컬스, 인크. 치료제, 및 그의 제조 및 사용 방법
KR101764575B1 (ko) * 2004-07-28 2017-08-03 다케다 야쿠힌 고교 가부시키가이샤 피롤로〔2,3-ｃ〕피리딘 화합물, 그 제조 방법 및 용도
JP2008508347A (ja) * 2004-08-02 2008-03-21 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング ５置換された１Ｈ−ピロロ［３，２−ｂ］ピリジン
US8148529B2 (en) * 2004-09-03 2012-04-03 Yuhan Corporation Pyrrolo[3,2-C] pyridine derivatives and processes for the preparation thereof
PL1784404T3 (pl) 2004-09-03 2012-04-30 Yuhan Corp Pochodne pirolo[2,3-c]pirydyny i sposoby ich wytwarzania
JP4989477B2 (ja) * 2004-09-03 2012-08-01 ユーハン・コーポレイション ピロロ［３，２−ｃ］ピリジン誘導体及びその製造方法
EP1784403B1 (en) * 2004-09-03 2013-07-17 Yuhan Corporation Pyrrolo[3,2-b]pyridine derivatives and processes for the preparation thereof
US7777040B2 (en) 2005-05-03 2010-08-17 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
JP2009507032A (ja) 2005-09-02 2009-02-19 アボット・ラボラトリーズ 新規なイミダゾ系複素環
WO2007067416A2 (en) * 2005-12-05 2007-06-14 Affinium Pharmaceuticals, Inc. Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
WO2007145921A1 (en) * 2006-06-06 2007-12-21 Schering Corporation Imidazopyrazines as protein kinase inhibitors
JP5468899B2 (ja) * 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
EP2125802A4 (en) 2007-02-16 2014-08-20 Debiopharm Int Sa SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS
JP5496915B2 (ja) 2008-02-13 2014-05-21 シージーアイ ファーマシューティカルズ，インコーポレーテッド ６−アリール−イミダゾ［１，２−ａ］ピラジン誘導体、その製造方法、及びその使用方法
SG10201707798SA (en) 2008-12-08 2017-10-30 Gilead Connecticut Inc Imidazopyrazine syk inhibitors
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
ES2590804T3 (es) 2008-12-08 2016-11-23 Gilead Connecticut, Inc. Inhibidores de Imidazopyrazine Syk
AU2011226689B2 (en) 2010-03-11 2016-09-01 Kronos Bio, Inc. Imidazopyridines Syk inhibitors
KR101720885B1 (ko) 2012-06-19 2017-03-28 데비오팜 인터네셔날 에스 에이 (e)-n-메틸-n-((3-메틸벤조푸란-2-일)메틸)-3-(7-옥소-5,6,7,8-테트라히드로-1,8-나프티리딘-3-일)아크릴아미드의전구약물 유도체
KR20170116203A (ko) 2013-07-30 2017-10-18 질레드 코네티컷 인코포레이티드 Ｓｙｋ 억제제의 제제
NZ715776A (en) 2013-07-30 2017-04-28 Gilead Connecticut Inc Polymorph of syk inhibitors
DK3076976T3 (da) 2013-12-04 2020-12-07 Kronos Bio Inc Fremgangsmåder til behandling af cancer
GB201321738D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic Agents
US9290505B2 (en) 2013-12-23 2016-03-22 Gilead Sciences, Inc. Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
TWI735853B (zh) 2013-12-23 2021-08-11 美商克洛諾斯生技有限公司 脾酪胺酸激酶抑制劑
EA201790086A1 (ru) 2014-07-14 2017-07-31 Джилид Сайэнс, Инк. Комбинации для лечения раковых заболеваний
US10751351B2 (en) 2016-02-26 2020-08-25 Debiopharm International S.A. Medicament for treatment of diabetic foot infections
WO2019040298A1 (en) 2017-08-25 2019-02-28 Gilead Sciences, Inc. SYK INHIBITORY POLYMORPHS
LT3923914T (lt) 2019-02-14 2023-07-25 Debiopharm International S.A. Afabicino kompozicija, jos gamybos būdas
US11339168B2 (en) 2019-02-22 2022-05-24 Kronos Bio, Inc. Crystalline forms of 6-(6-aminopyrazin-2-yl)-N-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo[1,2-a]pyrazin-8-amine as Syk inhibitors
US12414958B2 (en) 2019-06-14 2025-09-16 Debiopharm International S.A. Medicament and use thereof for treating bacterial infections involving biofilm

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507294A (en) 1982-03-08 1985-03-26 Schering Corp. Imidazo[1,2-a]pyrazines
EP0068378B1 (en) * 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
IL97931A0 (en) * 1990-04-27 1992-06-21 Byk Gulden Lomberg Chem Fab Pyridazine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US5041442A (en) * 1990-07-31 1991-08-20 Syntex (U.S.A.) Inc. Pyrrolo(1,2-a)pyrazines as inhibitors of gastric acid secretion
WO1992006979A1 (de) * 1990-10-15 1992-04-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue diazine
DE59209687D1 (de) * 1991-10-25 1999-06-02 Byk Gulden Lomberg Chem Fab Pyrrolo-pyridazine mit magen- und darmschutzwirkungen
CN1044811C (zh) 1994-01-19 1999-08-25 三共株式会社 吡咯并哒嗪衍生物
SE9602286D0 (sv) 1996-06-10 1996-06-10 Astra Ab New compounds
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds

Also Published As

Publication number Publication date
US6518270B1 (en) 2003-02-11
HUP0100601A2 (hu) 2001-09-28
RU2241000C2 (ru) 2004-11-27
BR9814755A (pt) 2000-10-03
CZ292349B6 (cs) 2003-09-17
DE69811735T2 (de) 2003-12-18
EE200000315A (et) 2001-10-15
ZA9810468B (en) 1999-05-21
CA2311798A1 (en) 1999-06-10
TW515798B (en) 2003-01-01
HUP0100601A3 (en) 2002-10-28
JP2001525322A (ja) 2001-12-11
DK1042324T3 (da) 2003-05-05
EP1042324B1 (en) 2003-02-26
CN1142933C (zh) 2004-03-24
AU752187C (en) 2003-09-18
IS5486A (is) 2000-05-10
TR200001530T2 (tr) 2000-11-21
UA70932C2 (uk) 2004-11-15
MY121032A (en) 2005-12-30
IL136145A0 (en) 2001-05-20
SK6742000A3 (en) 2001-03-12
EE04060B1 (et) 2003-06-16
CN1284078A (zh) 2001-02-14
AR016972A1 (es) 2001-08-01
PL340920A1 (en) 2001-03-12
KR20010032559A (ko) 2001-04-25
NO20002721D0 (no) 2000-05-26
CZ20001947A3 (cs) 2000-11-15
NO20002721L (no) 2000-07-28
EP1042324A1 (en) 2000-10-11
AU1356599A (en) 1999-06-16
HK1030216A1 (en) 2001-04-27
ATE233263T1 (de) 2003-03-15
SK283904B6 (sk) 2004-04-06
WO1999028322A1 (en) 1999-06-10
DE69811735D1 (de) 2003-04-03
SE9704404D0 (sv) 1997-11-28
ES2191356T3 (es) 2003-09-01
NO315704B1 (no) 2003-10-13
NZ504355A (en) 2001-12-21
PT1042324E (pt) 2003-06-30
AU752187B2 (en) 2002-09-12

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