ID24527A - Proses pembuatan senyawa-senyawa farmasi - Google Patents

Proses pembuatan senyawa-senyawa farmasi

Info

Publication number
ID24527A
ID24527A IDW990900D ID990900D ID24527A ID 24527 A ID24527 A ID 24527A ID W990900 D IDW990900 D ID W990900D ID 990900 D ID990900 D ID 990900D ID 24527 A ID24527 A ID 24527A
Authority
ID
Indonesia
Prior art keywords
pharmaceutical compounds
making pharmaceutical
making
compounds
pharmaceutical
Prior art date
Application number
IDW990900D
Other languages
English (en)
Inventor
David W Hoard
Eric D Moher
Vinod F Patel
Original Assignee
Eli Lilly And Company Cs
Univ Hawaii
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company Cs, Univ Hawaii, Univ Wayne State filed Critical Eli Lilly And Company Cs
Publication of ID24527A publication Critical patent/ID24527A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D273/00Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/46Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
IDW990900D 1997-02-26 1998-02-25 Proses pembuatan senyawa-senyawa farmasi ID24527A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3911697P 1997-02-26 1997-02-26
US3911497P 1997-02-26 1997-02-26

Publications (1)

Publication Number Publication Date
ID24527A true ID24527A (id) 2000-07-20

Family

ID=26715826

Family Applications (2)

Application Number Title Priority Date Filing Date
IDW990901A ID22984A (id) 1997-02-26 1998-02-25 Proses epoksidasi selektif untuk pembuatan senyawa farmasi
IDW990900D ID24527A (id) 1997-02-26 1998-02-25 Proses pembuatan senyawa-senyawa farmasi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IDW990901A ID22984A (id) 1997-02-26 1998-02-25 Proses epoksidasi selektif untuk pembuatan senyawa farmasi

Country Status (17)

Country Link
US (1) US6143909A (id)
EP (2) EP0861838A3 (id)
JP (2) JP2002513403A (id)
KR (2) KR20000075671A (id)
CN (2) CN1255121A (id)
AU (2) AU738999B2 (id)
BR (2) BR9807265A (id)
CA (2) CA2281108A1 (id)
CZ (1) CZ9902998A3 (id)
EA (2) EA002547B1 (id)
ID (2) ID22984A (id)
IL (2) IL131205A0 (id)
NO (2) NO994049D0 (id)
NZ (1) NZ336918A (id)
PL (2) PL335478A1 (id)
TR (2) TR199902064T2 (id)
WO (2) WO1998038158A1 (id)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0932601A4 (en) * 1996-08-30 2000-02-02 Lilly Co Eli METHOD FOR PRODUCING PHARMACEUTICALS
AU4253997A (en) * 1996-09-06 1998-03-26 Eli Lilly And Company Process and novel intermediates
JP2002527509A (ja) * 1998-10-16 2002-08-27 イーライ・リリー・アンド・カンパニー 抗腫瘍剤を製造するための立体選択的な方法
WO2000034252A2 (en) * 1998-12-07 2000-06-15 Eli Lilly And Company Process for the preparation of cryptophycin derivatives
WO2000034253A2 (en) * 1998-12-07 2000-06-15 Eli Lilly And Company Intermediates and reaction sequence to produce said intermediates useful for the preparation of antineoplastic and antifungal cryptophycin derivatives
HK1049787B (en) 1999-10-01 2014-07-25 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US7229814B2 (en) * 2004-05-05 2007-06-12 Regents Of The University Of Minnesota Nucleic acids and polypeptides involved in the production of cryptophycin
CN101962323B (zh) * 2010-07-16 2013-06-05 中国人民解放军第二军医大学 2-丙烯酰x基-3-取代苯基丙酸类化合物及其用途
CN111333560B (zh) * 2020-04-13 2024-01-23 合肥工业大学 一种制备螺环β-内酰胺的方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946835A (en) * 1988-07-15 1990-08-07 Merck & Co., Inc. Antifungal fermentation product and method
US4868208A (en) * 1988-07-15 1989-09-19 Merck & Co., Inc. Antifungal agent and method
US4845086A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
US4845085A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
WO1990009395A1 (en) * 1989-02-17 1990-08-23 Coselco Mimotopes Pty. Ltd. Method for the use and synthesis of peptides
US5256802A (en) * 1990-04-03 1993-10-26 Miles Inc. Process for the production of oxiranes
JPH08505604A (ja) * 1992-11-06 1996-06-18 カイロン ミモトープス プロプライエトリー リミテッド モジュラーポリマーを合成するための支持体
GB2282384B8 (en) * 1993-08-18 1997-09-04 Europ Economic Community Drug delivery agents incorporating mitomycin
DE69427706T2 (de) * 1993-12-21 2001-10-25 University Of Hawaii, Honolulu Cryptophycine
US5952298A (en) * 1993-12-21 1999-09-14 The University Of Hawaii Cryptophycins
EP0785941B1 (en) * 1994-10-14 2000-04-19 Stratagene Porphyrin labeling of polynucleotides
TJ347B (en) * 1995-03-07 2002-10-06 Univ Hawaii Cryptophicin compounds pharmacentical composition method to inhibit the proliteration of cells and and method to treat neoplasia
CA2217051C (en) * 1995-03-31 2006-05-30 Nippon Chemiphar Co., Ltd. Epoxysuccinic acid derivatives
US5700826A (en) * 1995-06-07 1997-12-23 Ontogen Corporation 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
EP0850316A4 (en) * 1995-08-30 2000-08-23 Univ Hawaii CRYPTOPHYCINE, OBTAINED FROM ABBERANTER BIOSYNTHESIS
ES2194129T3 (es) * 1995-12-22 2003-11-16 Univ Hawaii Compuestos farmaceuticos.
AU724312B2 (en) * 1996-02-07 2000-09-14 Buckman Laboratories International, Inc. Synergistic antimicrobial compositions containing an ionene polymer and a salt of dodecylamine and methods of using the same
ES2156338T3 (es) * 1996-02-27 2001-06-16 Lilly Co Eli Derivados de criptoficina y su uso como agentes antimicrotubulos.
JP2001502297A (ja) * 1996-08-30 2001-02-20 イーライ・リリー・アンド・カンパニー 医薬用化合物
DE69736067T9 (de) * 1996-08-30 2007-10-31 University Of Hawaii, Honolulu Neue cryptophycin-derivate als antineoplastika
AU4169897A (en) * 1996-08-30 1998-03-19 Eli Lilly And Company Pharmaceutical compounds
US6025506A (en) * 1997-02-21 2000-02-15 Dsm N.V. Process for preparing an optically active phenylglycidyl acid derivative
TW438787B (en) * 1997-02-27 2001-06-07 Tanabe Seiyaku Co Process for preparing optically active trans-3-substituted glycidic acid ester

Also Published As

Publication number Publication date
TR199902065T2 (xx) 2000-02-21
CA2281108A1 (en) 1998-09-03
IL131205A0 (en) 2001-01-28
AU6667198A (en) 1998-09-18
TR199902064T2 (xx) 2001-10-22
BR9811252A (pt) 2000-09-26
CA2281104A1 (en) 1998-09-03
EP0861838A2 (en) 1998-09-02
ID22984A (id) 1999-12-23
PL335347A1 (en) 2000-04-25
WO1998038164A1 (en) 1998-09-03
BR9807265A (pt) 2000-05-23
NO994083D0 (no) 1999-08-24
NZ336918A (en) 2001-11-30
JP2002512603A (ja) 2002-04-23
AU738999B2 (en) 2001-10-04
PL335478A1 (en) 2000-04-25
EA199900772A1 (ru) 2000-04-24
AU6667298A (en) 1998-09-18
NO994083L (no) 1999-10-25
JP2002513403A (ja) 2002-05-08
NO994049L (no) 1999-08-23
EP0861838A3 (en) 1998-12-09
EP0861839A1 (en) 1998-09-02
NO994049D0 (no) 1999-08-23
EA002547B1 (ru) 2002-06-27
CN1255121A (zh) 2000-05-31
KR20000075671A (ko) 2000-12-26
CN1252788A (zh) 2000-05-10
US6143909A (en) 2000-11-07
EA199900770A1 (ru) 2000-04-24
IL131162A0 (en) 2001-01-28
CZ9902998A3 (cs) 2002-10-16
WO1998038158A1 (en) 1998-09-03
KR20000075623A (ko) 2000-12-26

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