ID20624A - Proses pembuatan 2'-flouro-5-metil-betha-l-rabinofuranosiluridin - Google Patents
Proses pembuatan 2'-flouro-5-metil-betha-l-rabinofuranosiluridinInfo
- Publication number
- ID20624A ID20624A IDP973206A ID973206A ID20624A ID 20624 A ID20624 A ID 20624A ID P973206 A IDP973206 A ID P973206A ID 973206 A ID973206 A ID 973206A ID 20624 A ID20624 A ID 20624A
- Authority
- ID
- Indonesia
- Prior art keywords
- rabinofuranosiluridin
- betha
- flouro
- methyl
- making
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/02—Monosaccharides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5348897P | 1997-07-23 | 1997-07-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID20624A true ID20624A (id) | 1999-01-28 |
Family
ID=21984622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDP973206A ID20624A (id) | 1997-07-23 | 1997-09-16 | Proses pembuatan 2'-flouro-5-metil-betha-l-rabinofuranosiluridin |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6512107B2 (id) |
| EP (2) | EP1327637B1 (id) |
| KR (1) | KR100247505B1 (id) |
| CN (1) | CN1113892C (id) |
| AR (1) | AR009092A1 (id) |
| AT (2) | ATE304547T1 (id) |
| AU (1) | AU8758298A (id) |
| BR (1) | BR9810804B1 (id) |
| DE (2) | DE69831619T2 (id) |
| DK (1) | DK1327637T3 (id) |
| ES (2) | ES2249678T3 (id) |
| ID (1) | ID20624A (id) |
| IL (1) | IL121730A (id) |
| IN (1) | IN186807B (id) |
| MY (1) | MY117314A (id) |
| PT (2) | PT1327637E (id) |
| SA (1) | SA98180771B1 (id) |
| SI (1) | SI1327637T1 (id) |
| TR (1) | TR199701051A2 (id) |
| TW (1) | TW434252B (id) |
| WO (2) | WO1999005157A1 (id) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW434252B (en) | 1997-07-23 | 2001-05-16 | Univ Georgia Res Found | Process for the preparation of 2'-fluoro-5-methyl-β-L-arabino-furanosyluridine |
| KR100449618B1 (ko) * | 1998-03-27 | 2004-11-16 | 부광약품 주식회사 | 2'-플루오로-5-메틸-β-L-아라비노푸라노실유리딘의 제조방법 |
| US6462191B1 (en) * | 2000-07-13 | 2002-10-08 | Air Products And Chemicals, Inc. | Synthesis of 2-deoxy-2-fluoro-arabinose derivatives |
| CN101117346B (zh) * | 2001-03-30 | 2012-12-12 | 富光药品株式会社 | 2'-卤代-β-L-阿拉伯呋喃糖基核苷的制备方法 |
| KR100487992B1 (ko) * | 2001-10-25 | 2005-05-09 | 부광약품 주식회사 | 2'-플루오로-5-메틸-β-엘-아라비노푸라노실유리딘의 황유도체 |
| US7211570B2 (en) * | 2001-12-20 | 2007-05-01 | Pharmasset, Inc. | Treatment of EBV and KHSV infection |
| KR100976778B1 (ko) | 2003-04-17 | 2010-08-18 | 부광약품 주식회사 | 1-（2'-플루오로-베타-엘-아라비노푸라노실）티민의 황 유도체를 유효 활성 성분으로 하는 b형 간염 바이러스 치료제 |
| SI3109244T1 (sl) | 2004-09-14 | 2019-06-28 | Gilead Pharmasset Llc | Priprava 2'fluoro-2'-alkil-substituiranih ali drugih neobvezno substituiranih ribofuranozil pirimidinov in purinov in njihovih derivatov |
| BRPI0613796A2 (pt) * | 2005-06-07 | 2011-02-15 | Univ Yale | composicões farmacêuticas e seus usos, e métodos de tratamento de cáncer e outras condições ou estados patológicos, por meio do uso de clevudina (lfmau) e telbivudina (ldt) |
| RU2443703C2 (ru) | 2007-06-18 | 2012-02-27 | Саншайн Лейк Фарма Ко., Лтд | Бром-фенил замещенные тиазолилдигидропиримидины |
| GB0907551D0 (en) | 2009-05-01 | 2009-06-10 | Univ Dundee | Treatment or prophylaxis of proliferative conditions |
| AU2019216531A1 (en) | 2018-02-02 | 2020-09-24 | Maverix Oncology, Inc. | Small molecule drug conjugates of gemcitabine monophosphate |
| CN109320564B (zh) * | 2018-10-26 | 2022-05-31 | 浙江晟格生物科技有限公司 | 一种l-来苏糖的制备工艺 |
| CN109467541A (zh) * | 2018-11-17 | 2019-03-15 | 扬州工业职业技术学院 | 一种绿色合成克拉夫定药物中间体的方法 |
| CN109467583A (zh) * | 2018-11-17 | 2019-03-15 | 扬州工业职业技术学院 | 一种克拉夫定的绿色合成工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3714473A1 (de) * | 1987-04-30 | 1988-11-10 | Basf Ag | Kontinuierliches verfahren zur epimerisierung von zuckern, insbesondere von d-arabinose zu d-ribose |
| JP2784230B2 (ja) | 1988-02-09 | 1998-08-06 | ユーオーピー・インコーポレーテッド | エピマーアルドースおよびアルドース同族体の連続相互変換に用いる固体触媒 |
| DE4002727A1 (de) * | 1990-01-31 | 1991-08-01 | Bayer Ag | Mischungen aus waessrigen polymerdispersionen |
| US5587362A (en) | 1994-01-28 | 1996-12-24 | Univ. Of Ga Research Foundation | L-nucleosides |
| US5808040A (en) | 1995-01-30 | 1998-09-15 | Yale University | L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides |
| TW434252B (en) | 1997-07-23 | 2001-05-16 | Univ Georgia Res Found | Process for the preparation of 2'-fluoro-5-methyl-β-L-arabino-furanosyluridine |
-
1997
- 1997-08-16 TW TW086111816A patent/TW434252B/zh not_active IP Right Cessation
- 1997-08-29 WO PCT/IB1997/001254 patent/WO1999005157A1/en active Application Filing
- 1997-09-08 CN CN97116278A patent/CN1113892C/zh not_active Expired - Lifetime
- 1997-09-10 IL IL12173097A patent/IL121730A/xx not_active IP Right Cessation
- 1997-09-13 MY MYPI97004259A patent/MY117314A/en unknown
- 1997-09-15 IN IN2616DE1997 patent/IN186807B/en unknown
- 1997-09-16 ID IDP973206A patent/ID20624A/id unknown
- 1997-09-25 AR ARP970104409A patent/AR009092A1/es active IP Right Grant
- 1997-09-26 TR TR97/01051A patent/TR199701051A2/xx unknown
-
1998
- 1998-01-04 SA SA98180771A patent/SA98180771B1/ar unknown
- 1998-01-19 KR KR1019980001421A patent/KR100247505B1/ko active IP Right Grant
- 1998-07-23 DE DE69831619T patent/DE69831619T2/de not_active Expired - Lifetime
- 1998-07-23 DE DE69812959T patent/DE69812959T2/de not_active Expired - Lifetime
- 1998-07-23 AU AU87582/98A patent/AU8758298A/en not_active Abandoned
- 1998-07-23 PT PT03075945T patent/PT1327637E/pt unknown
- 1998-07-23 US US09/121,294 patent/US6512107B2/en not_active Expired - Lifetime
- 1998-07-23 ES ES03075945T patent/ES2249678T3/es not_active Expired - Lifetime
- 1998-07-23 SI SI9830792T patent/SI1327637T1/sl unknown
- 1998-07-23 PT PT98939087T patent/PT998482E/pt unknown
- 1998-07-23 DK DK03075945T patent/DK1327637T3/da active
- 1998-07-23 EP EP03075945A patent/EP1327637B1/en not_active Expired - Lifetime
- 1998-07-23 ES ES98939087T patent/ES2195370T3/es not_active Expired - Lifetime
- 1998-07-23 AT AT03075945T patent/ATE304547T1/de active
- 1998-07-23 WO PCT/US1998/015375 patent/WO1999005158A1/en active IP Right Grant
- 1998-07-23 AT AT98939087T patent/ATE236187T1/de active
- 1998-07-23 EP EP98939087A patent/EP0998482B1/en not_active Expired - Lifetime
- 1998-07-23 BR BRPI9810804-2A patent/BR9810804B1/pt not_active IP Right Cessation
-
2003
- 2003-01-24 US US10/351,222 patent/US6894159B2/en not_active Expired - Lifetime
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