NO994083D0 - Selektiv epoksideringsmetode for fremstilling av farmasöytiske forbindelser - Google Patents

Selektiv epoksideringsmetode for fremstilling av farmasöytiske forbindelser

Info

Publication number
NO994083D0
NO994083D0 NO994083A NO994083A NO994083D0 NO 994083 D0 NO994083 D0 NO 994083D0 NO 994083 A NO994083 A NO 994083A NO 994083 A NO994083 A NO 994083A NO 994083 D0 NO994083 D0 NO 994083D0
Authority
NO
Norway
Prior art keywords
preparation
pharmaceutical compounds
epoxidation method
selective epoxidation
selective
Prior art date
Application number
NO994083A
Other languages
English (en)
Other versions
NO994083L (no
Inventor
David W Hoard
Eric D Moher
Bryan H Norman
Vinod Francis Patel
Original Assignee
Lilly Co Eli
Univ Hawaii
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Univ Hawaii, Univ Wayne State filed Critical Lilly Co Eli
Publication of NO994083D0 publication Critical patent/NO994083D0/no
Publication of NO994083L publication Critical patent/NO994083L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D273/00Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/46Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NO994083A 1997-02-26 1999-08-24 Selektiv epoksideringsmetode for fremstilling av farmasöytiske forbindelser NO994083L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3911497P 1997-02-26 1997-02-26
US3911697P 1997-02-26 1997-02-26
PCT/US1998/003667 WO1998038164A1 (en) 1997-02-26 1998-02-25 Selective epoxidation process for preparing pharmaceutical compounds

Publications (2)

Publication Number Publication Date
NO994083D0 true NO994083D0 (no) 1999-08-24
NO994083L NO994083L (no) 1999-10-25

Family

ID=26715826

Family Applications (2)

Application Number Title Priority Date Filing Date
NO994049A NO994049L (no) 1997-02-26 1999-08-23 Metode for aa fremstille farmasöytiske forbindelser
NO994083A NO994083L (no) 1997-02-26 1999-08-24 Selektiv epoksideringsmetode for fremstilling av farmasöytiske forbindelser

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO994049A NO994049L (no) 1997-02-26 1999-08-23 Metode for aa fremstille farmasöytiske forbindelser

Country Status (17)

Country Link
US (1) US6143909A (no)
EP (2) EP0861839A1 (no)
JP (2) JP2002513403A (no)
KR (2) KR20000075623A (no)
CN (2) CN1252788A (no)
AU (2) AU6667198A (no)
BR (2) BR9811252A (no)
CA (2) CA2281108A1 (no)
CZ (1) CZ9902998A3 (no)
EA (2) EA199900770A1 (no)
ID (2) ID22984A (no)
IL (2) IL131205A0 (no)
NO (2) NO994049L (no)
NZ (1) NZ336918A (no)
PL (2) PL335478A1 (no)
TR (2) TR199902065T2 (no)
WO (2) WO1998038164A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977387A (en) * 1996-08-30 1999-11-02 Eli Lilly And Company Process for preparing pharmaceutical compounds
CA2264557A1 (en) * 1996-09-06 1998-03-12 Eli Lilly And Company Process and novel intermediates
KR20010099699A (ko) * 1998-10-16 2001-11-09 웨인 스테이트 유니버시티 크립토피신의 입체선택적 제조 방법
WO2000034253A2 (en) * 1998-12-07 2000-06-15 Eli Lilly And Company Intermediates and reaction sequence to produce said intermediates useful for the preparation of antineoplastic and antifungal cryptophycin derivatives
WO2000034252A2 (en) * 1998-12-07 2000-06-15 Eli Lilly And Company Process for the preparation of cryptophycin derivatives
WO2001024763A2 (en) 1999-10-01 2001-04-12 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
EP1751279A4 (en) * 2004-05-05 2008-03-19 Univ Minnesota NUCLEIC ACIDS AND POLYPEPTIDES INVOLVED IN THE PREPARATION OF CRYPTOPHYCIN
CN101962323B (zh) * 2010-07-16 2013-06-05 中国人民解放军第二军医大学 2-丙烯酰x基-3-取代苯基丙酸类化合物及其用途
CN111333560B (zh) * 2020-04-13 2024-01-23 合肥工业大学 一种制备螺环β-内酰胺的方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946835A (en) * 1988-07-15 1990-08-07 Merck & Co., Inc. Antifungal fermentation product and method
US4868208A (en) * 1988-07-15 1989-09-19 Merck & Co., Inc. Antifungal agent and method
US4845086A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
US4845085A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
NZ232562A (en) * 1989-02-17 1992-10-28 Coselco Mimotopes Pty Ltd Immobilised peptide - solid support comprising a cleavable ester link between the peptide carboxy terminus and the solid support
US5256802A (en) * 1990-04-03 1993-10-26 Miles Inc. Process for the production of oxiranes
NZ257077A (en) * 1992-11-06 1997-05-26 Chiron Mimotopes Pty Ltd Support for synthesis of modular polymers
GB2282384B8 (en) * 1993-08-18 1997-09-04 Europ Economic Community Drug delivery agents incorporating mitomycin
US5952298A (en) * 1993-12-21 1999-09-14 The University Of Hawaii Cryptophycins
CA2179490A1 (en) * 1993-12-21 1995-06-29 Trimurtulu Golakoti New cryptophycins
DE69516415T2 (de) * 1994-10-14 2000-09-14 Stratagene La Jolla Porphyrin-markierung von polynukleotiden
DE69633667T2 (de) * 1995-03-07 2006-03-02 University Of Hawaii, Honolulu Neue synthetische cryptophycine
AU716620B2 (en) * 1995-03-31 2000-03-02 Nippon Chemiphar Co. Ltd. Epoxysuccinic acid derivatives
US5700826A (en) * 1995-06-07 1997-12-23 Ontogen Corporation 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
CA2230540A1 (en) * 1995-08-30 1997-03-06 Eli Lilly And Company Pharmaceutical compounds
AU1469097A (en) * 1995-12-22 1997-07-17 Eli Lilly And Company Pharmaceutical compounds
US5843865A (en) * 1996-02-07 1998-12-01 Buckman Laboratories International, Inc. Synergistic antimicrobial compositions containing an ionene polymer and a salt of dodecylamine and methods of using the same
ES2156338T3 (es) * 1996-02-27 2001-06-16 Lilly Co Eli Derivados de criptoficina y su uso como agentes antimicrotubulos.
CA2264297A1 (en) * 1996-08-30 1998-03-05 Chuan Shih Pharmaceutical compounds
AU4330097A (en) * 1996-08-30 1998-03-19 Eli Lilly And Company Pharmaceutical compounds
CN100356916C (zh) * 1996-08-30 2007-12-26 夏威夷大学 药物化合物
US6025506A (en) * 1997-02-21 2000-02-15 Dsm N.V. Process for preparing an optically active phenylglycidyl acid derivative
TW438787B (en) * 1997-02-27 2001-06-07 Tanabe Seiyaku Co Process for preparing optically active trans-3-substituted glycidic acid ester

Also Published As

Publication number Publication date
NZ336918A (en) 2001-11-30
EA199900772A1 (ru) 2000-04-24
NO994049D0 (no) 1999-08-23
TR199902065T2 (xx) 2000-02-21
WO1998038164A1 (en) 1998-09-03
US6143909A (en) 2000-11-07
AU6667298A (en) 1998-09-18
BR9811252A (pt) 2000-09-26
PL335478A1 (en) 2000-04-25
EA199900770A1 (ru) 2000-04-24
WO1998038158A1 (en) 1998-09-03
TR199902064T2 (xx) 2001-10-22
NO994083L (no) 1999-10-25
CA2281104A1 (en) 1998-09-03
IL131205A0 (en) 2001-01-28
EA002547B1 (ru) 2002-06-27
CN1255121A (zh) 2000-05-31
KR20000075671A (ko) 2000-12-26
ID24527A (id) 2000-07-20
CZ9902998A3 (cs) 2002-10-16
NO994049L (no) 1999-08-23
JP2002513403A (ja) 2002-05-08
CA2281108A1 (en) 1998-09-03
EP0861838A3 (en) 1998-12-09
PL335347A1 (en) 2000-04-25
CN1252788A (zh) 2000-05-10
EP0861839A1 (en) 1998-09-02
IL131162A0 (en) 2001-01-28
JP2002512603A (ja) 2002-04-23
BR9807265A (pt) 2000-05-23
KR20000075623A (ko) 2000-12-26
EP0861838A2 (en) 1998-09-02
AU6667198A (en) 1998-09-18
AU738999B2 (en) 2001-10-04
ID22984A (id) 1999-12-23

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