ES2194129T3 - Compuestos farmaceuticos. - Google Patents

Compuestos farmaceuticos.

Info

Publication number
ES2194129T3
ES2194129T3 ES96945283T ES96945283T ES2194129T3 ES 2194129 T3 ES2194129 T3 ES 2194129T3 ES 96945283 T ES96945283 T ES 96945283T ES 96945283 T ES96945283 T ES 96945283T ES 2194129 T3 ES2194129 T3 ES 2194129T3
Authority
ES
Spain
Prior art keywords
pharmaceutical compounds
cryptophycin compounds
novel cryptophycin
compounds
disrupting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96945283T
Other languages
English (en)
Inventor
Chuan Shih
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Hawaii
Wayne State University
Original Assignee
University of Hawaii
Wayne State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Hawaii, Wayne State University filed Critical University of Hawaii
Application granted granted Critical
Publication of ES2194129T3 publication Critical patent/ES2194129T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA INVENCION DESCRIBE NUEVOS COMPUESTOS DE CRIPTOFICINA QUE PUEDEN RESULTAR UTILES PARA INTERRUMPIR EL SISTEMA DE MICROTUBULINA, COMO AGENTES ANTINEOPLASICOS Y PARA EL TRATAMIENTO DEL CANCER. LA INVENCION INCLUYE ADEMAS UN FORMULADO PARA ADMINISTRAR LOS NUEVOS COMPUESTOS DE CRIPTOFICINA.
ES96945283T 1995-12-22 1996-12-20 Compuestos farmaceuticos. Expired - Lifetime ES2194129T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US914595P 1995-12-22 1995-12-22
US2507996P 1996-08-30 1996-08-30

Publications (1)

Publication Number Publication Date
ES2194129T3 true ES2194129T3 (es) 2003-11-16

Family

ID=26679113

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96945283T Expired - Lifetime ES2194129T3 (es) 1995-12-22 1996-12-20 Compuestos farmaceuticos.

Country Status (8)

Country Link
EP (1) EP0869786B1 (es)
JP (1) JP2000502351A (es)
AT (1) ATE233745T1 (es)
AU (1) AU1469097A (es)
CA (1) CA2241086A1 (es)
DE (1) DE69626544T2 (es)
ES (1) ES2194129T3 (es)
WO (1) WO1997023211A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA001913B1 (ru) * 1996-08-30 2001-10-22 Эли Лилли Энд Компани Фармацевтические соединения
US6680311B1 (en) 1996-08-30 2004-01-20 Eli Lilly And Company Cryptophycin compounds
CA2264527A1 (en) * 1996-09-06 1998-03-12 Eric David Moher Process to prepare pharmaceutical compounds
WO1998038178A1 (en) * 1997-02-26 1998-09-03 Eli Lilly And Company Tripeptide and tetrapeptide pharmaceutical compounds
EP0861838A3 (en) * 1997-02-26 1998-12-09 Eli Lilly And Company Process and intermediates for preparing cryptophycin compounds
EP0870506A1 (en) * 1997-04-11 1998-10-14 Eli Lilly And Company Compositions comprising a cryptophycin compound in combination with a synchronizing or activating agent for treating cancer
US6376230B1 (en) 1998-10-16 2002-04-23 Eli Lilly And Company Stereoselective process for producing intermediates of cryptophycins
US6103913A (en) * 1998-10-16 2000-08-15 Eli Lilly And Company Process for preparing enollactone derivatives
JP4776843B2 (ja) 1999-10-01 2011-09-21 イムノゲン インコーポレーティッド 免疫複合体及び化学療法剤を用いる癌治療用組成物及び方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116954A (en) * 1988-04-06 1992-05-26 Lipha, Lyonnaise Industrielle Pharmaceutique Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety
GB8814813D0 (en) * 1988-06-22 1988-07-27 Beecham Group Plc Novel compounds
US4845085A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
US4845086A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
JPH09510436A (ja) * 1993-12-21 1997-10-21 ユニバーシティー オブ ハワイ 新規なクリプトフィシン類
EP0850316A4 (en) * 1995-08-30 2000-08-23 Univ Hawaii CRYPTOPHYCINS OBTAINED FROM AN ABERRANT BIOSYNTHESIS
AU4330097A (en) * 1996-08-30 1998-03-19 Eli Lilly And Company Pharmaceutical compounds
CA2264297A1 (en) * 1996-08-30 1998-03-05 Chuan Shih Pharmaceutical compounds

Also Published As

Publication number Publication date
WO1997023211A1 (en) 1997-07-03
ATE233745T1 (de) 2003-03-15
EP0869786A4 (en) 1999-04-14
AU1469097A (en) 1997-07-17
DE69626544T2 (de) 2004-01-15
DE69626544D1 (de) 2003-04-10
CA2241086A1 (en) 1997-07-03
EP0869786B1 (en) 2003-03-05
JP2000502351A (ja) 2000-02-29
EP0869786A1 (en) 1998-10-14

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