DE69626544D1 - Arzneistoffe - Google Patents

Arzneistoffe

Info

Publication number
DE69626544D1
DE69626544D1 DE69626544T DE69626544T DE69626544D1 DE 69626544 D1 DE69626544 D1 DE 69626544D1 DE 69626544 T DE69626544 T DE 69626544T DE 69626544 T DE69626544 T DE 69626544T DE 69626544 D1 DE69626544 D1 DE 69626544D1
Authority
DE
Germany
Prior art keywords
drug substances
cryptophycin compounds
novel cryptophycin
disrupting
administering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69626544T
Other languages
English (en)
Other versions
DE69626544T2 (de
Inventor
Chuan Shih
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Hawaii
Wayne State University
Eli Lilly and Co
Original Assignee
University of Hawaii
Wayne State University
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Hawaii, Wayne State University, Eli Lilly and Co filed Critical University of Hawaii
Publication of DE69626544D1 publication Critical patent/DE69626544D1/de
Application granted granted Critical
Publication of DE69626544T2 publication Critical patent/DE69626544T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE69626544T 1995-12-22 1996-12-20 Arzneistoffe Expired - Fee Related DE69626544T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US914595P 1995-12-22 1995-12-22
US2507996P 1996-08-30 1996-08-30
PCT/US1996/020633 WO1997023211A1 (en) 1995-12-22 1996-12-20 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
DE69626544D1 true DE69626544D1 (de) 2003-04-10
DE69626544T2 DE69626544T2 (de) 2004-01-15

Family

ID=26679113

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69626544T Expired - Fee Related DE69626544T2 (de) 1995-12-22 1996-12-20 Arzneistoffe

Country Status (8)

Country Link
EP (1) EP0869786B1 (de)
JP (1) JP2000502351A (de)
AT (1) ATE233745T1 (de)
AU (1) AU1469097A (de)
CA (1) CA2241086A1 (de)
DE (1) DE69626544T2 (de)
ES (1) ES2194129T3 (de)
WO (1) WO1997023211A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6680311B1 (en) 1996-08-30 2004-01-20 Eli Lilly And Company Cryptophycin compounds
ATE328592T1 (de) * 1996-08-30 2006-06-15 Univ Hawaii Neue cryptophycin-derivate als antineoplastika
IL128643A0 (en) * 1996-09-06 2000-01-31 Lilly Co Eli Process to prepare pharmaceutical compounds
IL131162A0 (en) * 1997-02-26 2001-01-28 Lilly Co Eli Selective epoxidation process for preparing pharmaceutical compounds
CA2281107A1 (en) * 1997-02-26 1998-09-03 Eli Lilly And Company Tripeptide and tetrapeptide pharmaceutical compounds
EP0870506A1 (de) * 1997-04-11 1998-10-14 Eli Lilly And Company Zusammentsetzungen enthaltend ein Cryptophycin Derivat in Kombination mit einem synchronisierten Wirkstoff oder Aktivierungsmittel zur Behandlung von Krebs
US6376230B1 (en) 1998-10-16 2002-04-23 Eli Lilly And Company Stereoselective process for producing intermediates of cryptophycins
US6103913A (en) * 1998-10-16 2000-08-15 Eli Lilly And Company Process for preparing enollactone derivatives
EP1229934B1 (de) 1999-10-01 2014-03-05 Immunogen, Inc. Zusammensetzungen und verfahren zur behandlung von krebs mittels immunkonjugaten und chemotherapeutischen agenzien

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116954A (en) * 1988-04-06 1992-05-26 Lipha, Lyonnaise Industrielle Pharmaceutique Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety
GB8814813D0 (en) * 1988-06-22 1988-07-27 Beecham Group Plc Novel compounds
US4845086A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
US4845085A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
CA2179490A1 (en) * 1993-12-21 1995-06-29 Trimurtulu Golakoti New cryptophycins
AU6904896A (en) * 1995-08-30 1997-03-19 Eli Lilly And Company Pharmaceutical compounds
AU4330097A (en) * 1996-08-30 1998-03-19 Eli Lilly And Company Pharmaceutical compounds
CA2264297A1 (en) * 1996-08-30 1998-03-05 Chuan Shih Pharmaceutical compounds

Also Published As

Publication number Publication date
EP0869786A4 (de) 1999-04-14
AU1469097A (en) 1997-07-17
WO1997023211A1 (en) 1997-07-03
ES2194129T3 (es) 2003-11-16
CA2241086A1 (en) 1997-07-03
EP0869786B1 (de) 2003-03-05
JP2000502351A (ja) 2000-02-29
DE69626544T2 (de) 2004-01-15
EP0869786A1 (de) 1998-10-14
ATE233745T1 (de) 2003-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee