ATE233745T1 - Arzneistoffe - Google Patents

Arzneistoffe

Info

Publication number
ATE233745T1
ATE233745T1 AT96945283T AT96945283T ATE233745T1 AT E233745 T1 ATE233745 T1 AT E233745T1 AT 96945283 T AT96945283 T AT 96945283T AT 96945283 T AT96945283 T AT 96945283T AT E233745 T1 ATE233745 T1 AT E233745T1
Authority
AT
Austria
Prior art keywords
medicinal substances
cryptophycin compounds
novel cryptophycin
disrupting
administering
Prior art date
Application number
AT96945283T
Other languages
English (en)
Inventor
Chuan Shih
Original Assignee
Lilly Co Eli
Univ Hawaii
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Univ Hawaii, Univ Wayne State filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE233745T1 publication Critical patent/ATE233745T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AT96945283T 1995-12-22 1996-12-20 Arzneistoffe ATE233745T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US914595P 1995-12-22 1995-12-22
US2507996P 1996-08-30 1996-08-30
PCT/US1996/020633 WO1997023211A1 (en) 1995-12-22 1996-12-20 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
ATE233745T1 true ATE233745T1 (de) 2003-03-15

Family

ID=26679113

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96945283T ATE233745T1 (de) 1995-12-22 1996-12-20 Arzneistoffe

Country Status (8)

Country Link
EP (1) EP0869786B1 (de)
JP (1) JP2000502351A (de)
AT (1) ATE233745T1 (de)
AU (1) AU1469097A (de)
CA (1) CA2241086A1 (de)
DE (1) DE69626544T2 (de)
ES (1) ES2194129T3 (de)
WO (1) WO1997023211A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6680311B1 (en) 1996-08-30 2004-01-20 Eli Lilly And Company Cryptophycin compounds
CA2264063C (en) * 1996-08-30 2007-03-13 Eli Lilly And Company Cryptophycin compounds
JP2001500128A (ja) * 1996-09-06 2001-01-09 イーライ・リリー・アンド・カンパニー 薬用組成物を製造する方法
AU6338698A (en) * 1997-02-26 1998-09-18 Eli Lilly And Company Tripeptide and tetrapeptide pharmaceutical compounds
CA2281104A1 (en) * 1997-02-26 1998-09-03 University Of Hawaii Selective epoxidation process for preparing pharmaceutical compounds
EP0870506A1 (de) * 1997-04-11 1998-10-14 Eli Lilly And Company Zusammentsetzungen enthaltend ein Cryptophycin Derivat in Kombination mit einem synchronisierten Wirkstoff oder Aktivierungsmittel zur Behandlung von Krebs
US6376230B1 (en) 1998-10-16 2002-04-23 Eli Lilly And Company Stereoselective process for producing intermediates of cryptophycins
US6103913A (en) * 1998-10-16 2000-08-15 Eli Lilly And Company Process for preparing enollactone derivatives
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116954A (en) * 1988-04-06 1992-05-26 Lipha, Lyonnaise Industrielle Pharmaceutique Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety
GB8814813D0 (en) * 1988-06-22 1988-07-27 Beecham Group Plc Novel compounds
US4845086A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
US4845085A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
DE69427706T2 (de) * 1993-12-21 2001-10-25 University Of Hawaii, Honolulu Cryptophycine
WO1997008334A1 (en) * 1995-08-30 1997-03-06 University Of Hawaii Cryptophycins from aberrant biosynthesis
WO1998008506A1 (en) * 1996-08-30 1998-03-05 Eli Lilly And Company Pharmaceutical compounds
EP0923564A4 (de) * 1996-08-30 1999-12-08 Lilly Co Eli Pharmazeutische verbindungen

Also Published As

Publication number Publication date
AU1469097A (en) 1997-07-17
JP2000502351A (ja) 2000-02-29
WO1997023211A1 (en) 1997-07-03
EP0869786A1 (de) 1998-10-14
EP0869786B1 (de) 2003-03-05
DE69626544T2 (de) 2004-01-15
ES2194129T3 (es) 2003-11-16
DE69626544D1 (de) 2003-04-10
EP0869786A4 (de) 1999-04-14
CA2241086A1 (en) 1997-07-03

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties