IS5486A - Heterósýklísk efnasambönd til að hindra magasýruflæði, aðferðir við framleiðslu þeirra og lyfjablöndur er innihalda þau - Google Patents

Heterósýklísk efnasambönd til að hindra magasýruflæði, aðferðir við framleiðslu þeirra og lyfjablöndur er innihalda þau

Info

Publication number
IS5486A
IS5486A IS5486A IS5486A IS5486A IS 5486 A IS5486 A IS 5486A IS 5486 A IS5486 A IS 5486A IS 5486 A IS5486 A IS 5486A IS 5486 A IS5486 A IS 5486A
Authority
IS
Iceland
Prior art keywords
pharmaceutical compositions
compositions containing
production methods
heterocyclic compounds
gastric acid
Prior art date
Application number
IS5486A
Other languages
English (en)
Inventor
Amin Kosrat
Dahlström Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IS5486A publication Critical patent/IS5486A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS5486A 1997-11-28 2000-05-10 Heterósýklísk efnasambönd til að hindra magasýruflæði, aðferðir við framleiðslu þeirra og lyfjablöndur er innihalda þau IS5486A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704404A SE9704404D0 (sv) 1997-11-28 1997-11-28 New compounds
PCT/SE1998/002091 WO1999028322A1 (en) 1997-11-28 1998-11-18 Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
IS5486A true IS5486A (is) 2000-05-10

Family

ID=20409181

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5486A IS5486A (is) 1997-11-28 2000-05-10 Heterósýklísk efnasambönd til að hindra magasýruflæði, aðferðir við framleiðslu þeirra og lyfjablöndur er innihalda þau

Country Status (32)

Country Link
US (1) US6518270B1 (is)
EP (1) EP1042324B1 (is)
JP (1) JP2001525322A (is)
KR (1) KR20010032559A (is)
CN (1) CN1142933C (is)
AR (1) AR016972A1 (is)
AT (1) ATE233263T1 (is)
AU (1) AU752187C (is)
BR (1) BR9814755A (is)
CA (1) CA2311798A1 (is)
CZ (1) CZ292349B6 (is)
DE (1) DE69811735T2 (is)
DK (1) DK1042324T3 (is)
EE (1) EE04060B1 (is)
ES (1) ES2191356T3 (is)
HU (1) HUP0100601A3 (is)
ID (1) ID24730A (is)
IL (1) IL136145A0 (is)
IS (1) IS5486A (is)
MY (1) MY121032A (is)
NO (1) NO315704B1 (is)
NZ (1) NZ504355A (is)
PL (1) PL340920A1 (is)
PT (1) PT1042324E (is)
RU (1) RU2241000C2 (is)
SE (1) SE9704404D0 (is)
SK (1) SK283904B6 (is)
TR (1) TR200001530T2 (is)
TW (1) TW515798B (is)
UA (1) UA70932C2 (is)
WO (1) WO1999028322A1 (is)
ZA (1) ZA9810468B (is)

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US7312341B2 (en) 2002-09-09 2007-12-25 Cgi Pharmaceuticals, Inc. 6-aryl-imidazo[1,2-a] pyrazin-8-ylamines, method of making, and method of use thereof
AU2003266621A1 (en) * 2002-09-25 2004-04-19 Sankyo Company, Limited Medicinal composition for treatment for or prevention of visceral pain
AU2003266622A1 (en) * 2002-09-25 2004-04-19 Sankyo Company, Limited Medicinal composition for inhibiting increase in blood gastrin concentration
EP1575951B1 (en) 2002-12-06 2014-06-25 Debiopharm International SA Heterocyclic compounds, methods of making them and their use in therapy
WO2004072081A1 (en) 2003-02-10 2004-08-26 Cellular Genomics, Inc. Certain 8-heteroaryl-6-phenyl-imidazo[1,2-a]pyrazines as modulators of kinase activity
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
DE602004016831D1 (de) * 2003-03-17 2008-11-13 Affinium Pharm Inc Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend
US7405295B2 (en) 2003-06-04 2008-07-29 Cgi Pharmaceuticals, Inc. Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
US7393848B2 (en) 2003-06-30 2008-07-01 Cgi Pharmaceuticals, Inc. Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds
US7259164B2 (en) 2003-08-11 2007-08-21 Cgi Pharmaceuticals, Inc. Certain substituted imidazo[1,2-a]pyrazines, as modulators of kinase activity
EP1682133A1 (en) 2003-11-03 2006-07-26 AstraZeneca AB Imidazo 1,2-a pyridine derivatives for the treatment of silent gastro-esophageal reflux
EP2848614A3 (en) 2004-06-04 2015-07-29 Debiopharm International SA Acrylamide derivatives as antibiotic agents
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US20070287726A1 (en) * 2004-08-02 2007-12-13 Altana Pharma Ag 5-Substituted 1H-Pyrrolo [3,2-B] Pyridines
KR100958828B1 (ko) * 2004-09-03 2010-05-24 주식회사유한양행 피롤로[3,2-ｂ]피리딘 유도체 및 그의 제조방법
DK1784404T3 (da) 2004-09-03 2012-02-13 Yuhan Corp Pyrrolo[2,3-c]pyridinderivater samt fremgangsmåder til deres fremstilling
MX2007002214A (es) 2004-09-03 2007-05-07 Yuhan Corp Derivados de pirrolo[3,2-c]piridina y procesos para su preparacion.
ATE466013T1 (de) * 2004-09-03 2010-05-15 Yuhan Corp Pyrroloä3,2-cüpyridinderivate und verfahren zu deren herstellung
WO2007024294A2 (en) 2005-05-03 2007-03-01 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
US7709468B2 (en) 2005-09-02 2010-05-04 Abbott Laboratories Imidazo based heterocycles
EP1973902A2 (en) * 2005-12-05 2008-10-01 Affinium Pharmaceuticals, Inc. 3-heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
AR061229A1 (es) * 2006-06-06 2008-08-13 Schering Corp Imidazopirazinas como inhibidores de la proteina quinasa
EP2687533B1 (en) 2006-07-20 2017-07-19 Debiopharm International SA Acrylamide derivatives as FAB I inhibitors
WO2008098374A1 (en) 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
JP5496915B2 (ja) 2008-02-13 2014-05-21 シージーアイ ファーマシューティカルズ，インコーポレーテッド ６−アリール−イミダゾ［１，２−ａ］ピラジン誘導体、その製造方法、及びその使用方法
EA021293B1 (ru) 2008-12-08 2015-05-29 Джилид Коннектикут, Инк. ИМИДАЗОПИРАЗИНОВЫЕ ИНГИБИТОРЫ Syk, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ИМИДАЗОПИРАЗИНОВЫЕ ИНГИБИТОРЫ Syk, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
CN102307474B (zh) 2008-12-08 2015-04-01 吉利德康涅狄格股份有限公司 咪唑并吡嗪syk抑制剂
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
CN103168039B (zh) 2010-03-11 2016-08-03 吉利德康涅狄格公司 咪唑并吡啶类syk抑制剂
SI2861608T1 (sl) 2012-06-19 2019-08-30 Debiopharm International Sa Derivati predzdravila (E)-N-metil-N-((3-metilbenzofuran-2-IL)metil)- 3-(7-okso-5,6,7,8-tetrahidro-1 ,8-nafthiridin-3-il)akrilamid
EA029281B1 (ru) 2013-07-30 2018-03-30 Джилид Коннектикут, Инк. Полиморф ингибиторов syk
CA2919522C (en) 2013-07-30 2019-02-26 Gilead Connecticut, Inc. Formulation of syk inhibitors
CN105764516A (zh) 2013-12-04 2016-07-13 吉利德科学公司 治疗癌症的方法
GB201321738D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic Agents
TWI662037B (zh) 2013-12-23 2019-06-11 美商基利科學股份有限公司 脾酪胺酸激酶抑制劑
US9290505B2 (en) 2013-12-23 2016-03-22 Gilead Sciences, Inc. Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
BR112016028641A2 (pt) 2014-07-14 2017-08-22 Gilead Sciences Inc ?método para tratar câncer?
BR122023021456A2 (pt) 2016-02-26 2024-02-20 Debiopharm International S.A. Uso de di-hidrogeno fosfato de {6- [(e)-3-{metil[(3-metil-1-benfofuran-2- iol)metil]amino)-3- oxopro-1-en-1-il]-2-oxo-3,4-di-hidro-1,8-naftiridin-1(2h)- il}metila para tratamento de osteomielite do pé diabético e composição farmacêutica
CA3073871A1 (en) 2017-08-25 2019-02-28 Gilead Sciences, Inc. Polymorphs of syk inhibitors
LT3923914T (lt) 2019-02-14 2023-07-25 Debiopharm International S.A. Afabicino kompozicija, jos gamybos būdas
CN113950479A (zh) 2019-02-22 2022-01-18 克洛诺斯生物股份有限公司 作为syk抑制剂的缩合吡嗪的固体形式
CN113939306B (zh) 2019-06-14 2024-07-19 德彪药业国际股份公司 用于治疗涉及生物膜的细菌感染的药物及其用途

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DE3269604D1 (en) * 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
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SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds

Also Published As

Publication number Publication date
CZ292349B6 (cs) 2003-09-17
CN1284078A (zh) 2001-02-14
HK1030216A1 (en) 2001-04-27
HUP0100601A3 (en) 2002-10-28
US6518270B1 (en) 2003-02-11
TW515798B (en) 2003-01-01
NO20002721L (no) 2000-07-28
AR016972A1 (es) 2001-08-01
HUP0100601A2 (hu) 2001-09-28
TR200001530T2 (tr) 2000-11-21
PL340920A1 (en) 2001-03-12
JP2001525322A (ja) 2001-12-11
ID24730A (id) 2000-08-03
BR9814755A (pt) 2000-10-03
PT1042324E (pt) 2003-06-30
SE9704404D0 (sv) 1997-11-28
ES2191356T3 (es) 2003-09-01
CA2311798A1 (en) 1999-06-10
SK6742000A3 (en) 2001-03-12
EE200000315A (et) 2001-10-15
EP1042324A1 (en) 2000-10-11
RU2241000C2 (ru) 2004-11-27
NO20002721D0 (no) 2000-05-26
AU752187C (en) 2003-09-18
ZA9810468B (en) 1999-05-21
IL136145A0 (en) 2001-05-20
MY121032A (en) 2005-12-30
EE04060B1 (et) 2003-06-16
NO315704B1 (no) 2003-10-13
AU752187B2 (en) 2002-09-12
CN1142933C (zh) 2004-03-24
WO1999028322A1 (en) 1999-06-10
ATE233263T1 (de) 2003-03-15
DE69811735T2 (de) 2003-12-18
CZ20001947A3 (cs) 2000-11-15
SK283904B6 (sk) 2004-04-06
EP1042324B1 (en) 2003-02-26
UA70932C2 (uk) 2004-11-15
KR20010032559A (ko) 2001-04-25
AU1356599A (en) 1999-06-16
DK1042324T3 (da) 2003-05-05
NZ504355A (en) 2001-12-21
DE69811735D1 (de) 2003-04-03

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