DK573384A - Sphingosinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse derivater - Google Patents

Sphingosinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse derivater Download PDF

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Publication number
DK573384A
DK573384A DK573384A DK573384A DK573384A DK 573384 A DK573384 A DK 573384A DK 573384 A DK573384 A DK 573384A DK 573384 A DK573384 A DK 573384A DK 573384 A DK573384 A DK 573384A
Authority
DK
Denmark
Prior art keywords
derivatives
sphingosin
procedures
preparation
pharmaceutical compositions
Prior art date
Application number
DK573384A
Other languages
English (en)
Other versions
DK573384D0 (da
Inventor
Roland Tschannen
Wolfgang Fraefel
Richard Robert Schmidt
Rudolf Klaeger
Peter Zimmermann
Original Assignee
Solco Basel Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH6493/83A external-priority patent/CH679209A5/de
Application filed by Solco Basel Ag filed Critical Solco Basel Ag
Publication of DK573384D0 publication Critical patent/DK573384D0/da
Publication of DK573384A publication Critical patent/DK573384A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK573384A 1983-12-05 1984-12-03 Sphingosinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse derivater DK573384A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH6493/83A CH679209A5 (en) 1983-12-05 1983-12-05 New neutral glyco-sphingolipid derivs.
CH467184 1984-09-28

Publications (2)

Publication Number Publication Date
DK573384D0 DK573384D0 (da) 1984-12-03
DK573384A true DK573384A (da) 1985-06-06

Family

ID=25696036

Family Applications (1)

Application Number Title Priority Date Filing Date
DK573384A DK573384A (da) 1983-12-05 1984-12-03 Sphingosinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse derivater

Country Status (11)

Country Link
US (1) US4952683A (da)
EP (1) EP0146810A3 (da)
AU (1) AU570087B2 (da)
CA (1) CA1259610A (da)
DK (1) DK573384A (da)
ES (2) ES8604986A1 (da)
FI (1) FI844775L (da)
HU (1) HU195516B (da)
NO (1) NO844815L (da)
PL (1) PL143901B1 (da)
YU (2) YU202784A (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
DK17885D0 (da) * 1985-01-14 1985-01-14 Karlsson Karl Anders Antiviralt middel
DE3683214D1 (de) * 1985-08-13 1992-02-13 Solco Basel Ag Neues verfahren zur herstellung von sphingosinderivaten.
US4769362A (en) * 1985-10-01 1988-09-06 Trustees Of Boston University Increased vascular perfusion following administration of lipids
JPH07116209B2 (ja) * 1986-04-11 1995-12-13 メクト株式会社 シアロシルセラミド類及びその製造方法
EP0508493A1 (en) * 1986-08-06 1992-10-14 Mect Corporation Ganglioside related compounds and method of producing the same
EP0299201A3 (de) * 1987-06-12 1990-08-22 Wilhelm Dr. Hoerrmann Fett-Aminoalkohol enthaltendes Arzneimittel
ATE115859T1 (de) * 1987-06-26 1995-01-15 Solco Basel Ag Neue pharmazeutische präparate sowie neue lactosylverbindungen und ihre herstellung.
US4957741A (en) * 1988-08-02 1990-09-18 Angio-Medical Corp. Method for the treatment of gastric ulcer
US5066496A (en) * 1988-08-03 1991-11-19 Angio-Medical Corporation Composition and method for treatment of gastric and duodenal ulcers and mucosal erosions
IT1235162B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisosfingolipidi
DE3916072A1 (de) * 1989-05-17 1990-11-22 Thera Ges Fuer Patente Ceramidderivate und ihre verwendung als inhibitoren der sphingolipidsynthese
DE4102817A1 (de) * 1991-01-31 1992-08-06 Merck Patent Gmbh Verfahren zur stereoselektiven herstellung von (beta)-fucopyranosyl-phosphaten und sehr reiner gdp-fucose
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
TW261533B (da) * 1992-07-16 1995-11-01 Kirin Brewery
AU683026B2 (en) * 1992-10-22 1997-10-30 Kirin Pharma Kabushiki Kaisha Novel shingoglycolipid and use thereof
CA2160566C (en) * 1993-04-15 2004-07-13 Tatsuo Higa Novel sphingoglycolipids and uses thereof
EP0716589A4 (en) * 1993-07-23 1997-06-11 Morris Herstein COSMETIC COMPOSITION STIMULATING THE RENEWAL OF THE SKIN WITH A PROLONGED IRRITATION ELIMINATION EFFECT
CA2142153A1 (en) * 1994-03-04 1995-09-05 Jacques Banville Sulfated .beta.-glycolipid derivatives as cell adhesion inhibitors
US5663151A (en) * 1994-03-04 1997-09-02 Bristol-Myers Squibb Company Sulfated α-glycolipid derivatives as cell adhesion inhibitors
US5686426A (en) * 1994-11-17 1997-11-11 Bristol-Myers Squibb Company Dicarboxymethylated glycolipid derivatives as cell adhesion inhibitors
JPH10501554A (ja) * 1995-02-03 1998-02-10 コリア インスティテュート オブ サイエンス アンド テクノロジー 新規な止血剤組成物
CA2230738A1 (en) 1997-03-03 1998-09-03 Hiromichi Ohta Production of optically active sphingoid compound
JP4553488B2 (ja) 1998-09-21 2010-09-29 大塚製薬株式会社 カルボキシメチルガラクトース誘導体
US20040180852A1 (en) * 2003-03-10 2004-09-16 Cara-Lynne Schengrund Use of multivalent glycodendrimers to inhibit the activity of human immunodeficiency virus
DE102004025000A1 (de) * 2004-05-21 2005-12-08 Bayer Technology Services Gmbh Verfahren zur Herstellung von chemischen und pharmazeutischen Produkten mit integrierter Mehrsäulen-Chromatographie
CN101460458A (zh) 2006-02-15 2009-06-17 阿勒根公司 具有1－磷酸－鞘氨醇(s1p)受体拮抗剂生物活性的带芳基或者杂芳基基团的吲哚－3－羧酸的酰胺、酯、硫代酰胺和硫羟酸酯化合物
US8097644B2 (en) * 2006-03-28 2012-01-17 Allergan, Inc. Indole compounds having sphingosine-1-phosphate (S1P) receptor antagonist
AU2007269299B2 (en) * 2006-06-30 2013-01-17 Brigham Young University Adjuvants and methods of use
JP2010515750A (ja) 2007-01-11 2010-05-13 アラーガン インコーポレイテッド スフィンゴシン−１−ホスフェート（ｓ１ｐ）受容体アンタゴニスト生物活性を有する６−置換インドール−３−カルボン酸アミド化合物
US8524917B2 (en) * 2007-01-11 2013-09-03 Allergan, Inc. 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity
CN101918360A (zh) * 2007-09-24 2010-12-15 阿勒根公司 具有1-磷酸-鞘氨醇(s1p)受体生物学活性的带芳基或者杂芳基基团的吲哚化合物
US8143291B2 (en) 2008-05-09 2012-03-27 Allergan, Inc. Indole compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (S1P) receptor biological activity
EP2328863A1 (en) * 2008-08-12 2011-06-08 Allergan, Inc. Sphingosine-1-phosphate (s1p) receptor antagonists and methods for use thereof
WO2011008475A1 (en) 2009-06-30 2011-01-20 Allergan, Inc. Optionally substituted 2-(arylmethyl, aryloxy or arylthio) -n- pyridin-2 -yl-aryl acetamide or 2, 2-bis (aryl) -n-pyridin-2-yl acetamide compounds as medicaments for the treatment of eye diseases
US8168795B2 (en) * 2009-08-11 2012-05-01 Allergan, Inc. Selective sphingosine-1-phosphate receptor antagonists
WO2011028927A1 (en) 2009-09-04 2011-03-10 Allergan, Inc. Selective sphingosine-1-phosphate receptor antagonists
AU2010300791A1 (en) 2009-09-29 2012-04-19 Allergan, Inc. Condensed ring pyridine compounds as subtype-selective modulators of sphingosine-1-phosphate-2 (S1P2) receptors
US8741875B2 (en) 2009-11-24 2014-06-03 Allergan, Inc. Compounds as receptor modulators with therapeutic utility
EP2504328A1 (en) 2009-11-24 2012-10-03 Allergan, Inc. Novel compounds as receptor modulators with therapeutic utility
CA2818751A1 (en) 2010-11-22 2012-05-31 Allergan, Inc. Novel compounds as receptor modulators with therapeutic utility
US9708354B2 (en) 2013-03-15 2017-07-18 Cerenis Therapeutics Holding Sa Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
US20140316154A1 (en) 2013-03-15 2014-10-23 Cerenis Therapeutics Holding Sa Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
US20240132440A1 (en) 2021-01-25 2024-04-25 Carbocode S.A. Method for the production of d-erythro-sphingosine and analogs thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1495548A (en) * 1974-04-16 1977-12-21 Tate & Lyle Ltd Sugar derivative containing vinyl groups and copolymers thereof
US4362720A (en) * 1977-04-14 1982-12-07 Chembiomed Ltd. Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals

Also Published As

Publication number Publication date
FI844775A7 (fi) 1985-06-06
AU3628684A (en) 1985-06-13
ES8604986A1 (es) 1986-03-16
PL143901B1 (en) 1988-03-31
US4952683A (en) 1990-08-28
FI844775L (fi) 1985-06-06
DK573384D0 (da) 1984-12-03
ES538231A0 (es) 1986-03-16
AU570087B2 (en) 1988-03-03
YU189686A (en) 1987-12-31
ES548901A0 (es) 1986-04-16
NO844815L (no) 1985-06-06
CA1259610A (en) 1989-09-19
EP0146810A3 (de) 1987-05-13
ES8606373A1 (es) 1986-04-16
YU202784A (en) 1987-02-28
HUT36833A (en) 1985-10-28
EP0146810A2 (de) 1985-07-03
PL250710A1 (en) 1985-07-16
HU195516B (en) 1988-05-30
FI844775A0 (fi) 1984-12-04

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