HUT61729A - Process for producing dihydroisoquinoline derivatives and pharmaceutical compositions comprising such compounds - Google Patents

Process for producing dihydroisoquinoline derivatives and pharmaceutical compositions comprising such compounds Download PDF

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Publication number
HUT61729A
HUT61729A HU913760A HU376091A HUT61729A HU T61729 A HUT61729 A HU T61729A HU 913760 A HU913760 A HU 913760A HU 376091 A HU376091 A HU 376091A HU T61729 A HUT61729 A HU T61729A
Authority
HU
Hungary
Prior art keywords
formula
physiologically acceptable
compounds
acid addition
compound
Prior art date
Application number
HU913760A
Other languages
English (en)
Hungarian (hu)
Other versions
HU913760D0 (en
Inventor
Reto Naef
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HU913760D0 publication Critical patent/HU913760D0/hu
Publication of HUT61729A publication Critical patent/HUT61729A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
HU913760A 1990-12-13 1991-12-02 Process for producing dihydroisoquinoline derivatives and pharmaceutical compositions comprising such compounds HUT61729A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909027055A GB9027055D0 (en) 1990-12-13 1990-12-13 Organic compounds

Publications (2)

Publication Number Publication Date
HU913760D0 HU913760D0 (en) 1992-02-28
HUT61729A true HUT61729A (en) 1993-03-01

Family

ID=10686945

Family Applications (1)

Application Number Title Priority Date Filing Date
HU913760A HUT61729A (en) 1990-12-13 1991-12-02 Process for producing dihydroisoquinoline derivatives and pharmaceutical compositions comprising such compounds

Country Status (25)

Country Link
US (1) US5177085A (OSRAM)
EP (1) EP0490823B1 (OSRAM)
JP (1) JPH0764820B2 (OSRAM)
KR (1) KR920012040A (OSRAM)
AT (1) ATE145201T1 (OSRAM)
AU (1) AU643575B2 (OSRAM)
CA (1) CA2057524A1 (OSRAM)
CZ (1) CZ281669B6 (OSRAM)
DE (1) DE69123124T2 (OSRAM)
DK (1) DK0490823T3 (OSRAM)
ES (1) ES2093694T3 (OSRAM)
FI (1) FI915844A7 (OSRAM)
GB (1) GB9027055D0 (OSRAM)
GR (1) GR3022034T3 (OSRAM)
HU (1) HUT61729A (OSRAM)
IE (1) IE914325A1 (OSRAM)
IL (1) IL100328A (OSRAM)
MX (1) MX9102502A (OSRAM)
MY (1) MY129941A (OSRAM)
NZ (1) NZ240936A (OSRAM)
PL (1) PL168329B1 (OSRAM)
PT (1) PT99775B (OSRAM)
RU (1) RU2060992C1 (OSRAM)
TW (1) TW201736B (OSRAM)
ZA (1) ZA919858B (OSRAM)

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US5948820A (en) * 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
WO1996006068A1 (en) * 1994-08-22 1996-02-29 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and medicinal use thereof
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WO1997034473A1 (en) * 1996-03-21 1997-09-25 The Trustees Of Columbia University In The City Of New York Craf1 (traf-3) isoforms and uses thereof
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JP2001507349A (ja) 1996-12-23 2001-06-05 セルテック セラピューティックス リミテッド 縮合多環式２−アミノピリミジン誘導体、それらの製造およびたんぱく質チロシンキナーゼ抑制因子としてのそれらの使用
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JP2001518468A (ja) * 1997-09-30 2001-10-16 モレキュラー デザインズ インターナショナル，インコーポレイテッド β３アドレナリン受容体拮抗薬、拮抗薬合成物およびこれらの応用方法
IT1296985B1 (it) 1997-12-19 1999-08-03 Zambon Spa Derivati benzazinici inibitori della fosfodiesterasi 4
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HU229439B1 (hu) 1999-08-21 2013-12-30 Takeda Gmbh Roflumilast és salmeterol szinergetikus kombinációja
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GB8800397D0 (en) * 1988-01-08 1988-02-10 Sandoz Ltd Improvements in/relating to organic compounds

Also Published As

Publication number Publication date
US5177085A (en) 1993-01-05
IE914325A1 (en) 1992-06-17
HU913760D0 (en) 1992-02-28
ATE145201T1 (de) 1996-11-15
CZ281669B6 (cs) 1996-12-11
AU8898591A (en) 1992-06-18
NZ240936A (en) 1993-09-27
AU643575B2 (en) 1993-11-18
FI915844A0 (fi) 1991-12-11
RU2060992C1 (ru) 1996-05-27
EP0490823A1 (en) 1992-06-17
PL168329B1 (pl) 1996-02-29
IL100328A0 (en) 1992-09-06
MY129941A (en) 2007-05-31
MX9102502A (es) 1992-06-01
PL292738A1 (en) 1992-12-14
FI915844L (fi) 1992-06-14
JPH0764820B2 (ja) 1995-07-12
TW201736B (OSRAM) 1993-03-11
PT99775A (pt) 1992-11-30
KR920012040A (ko) 1992-07-25
ZA919858B (en) 1993-06-14
FI915844A7 (fi) 1992-06-14
DE69123124T2 (de) 1997-05-15
DK0490823T3 (OSRAM) 1997-02-17
EP0490823B1 (en) 1996-11-13
GB9027055D0 (en) 1991-02-06
CS375791A3 (en) 1992-06-17
PT99775B (pt) 1999-05-31
ES2093694T3 (es) 1997-01-01
DE69123124D1 (de) 1996-12-19
IL100328A (en) 1995-12-08
JPH04275276A (ja) 1992-09-30
CA2057524A1 (en) 1992-06-14
GR3022034T3 (en) 1997-03-31

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Owner name: NOVARTIS AG., CH

DFC4 Cancellation of temporary protection due to refusal