PT99775A - Processo para a preparacao de novos derivados de di-hidroisoquinolina - Google Patents
Processo para a preparacao de novos derivados de di-hidroisoquinolinaInfo
- Publication number
- PT99775A PT99775A PT99775A PT9977591A PT99775A PT 99775 A PT99775 A PT 99775A PT 99775 A PT99775 A PT 99775A PT 9977591 A PT9977591 A PT 9977591A PT 99775 A PT99775 A PT 99775A
- Authority
- PT
- Portugal
- Prior art keywords
- dihydroisoquinolin
- derivatives
- preparation
- new
- 4alkoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909027055A GB9027055D0 (en) | 1990-12-13 | 1990-12-13 | Organic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
PT99775A true PT99775A (pt) | 1992-11-30 |
PT99775B PT99775B (pt) | 1999-05-31 |
Family
ID=10686945
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99775A PT99775B (pt) | 1990-12-13 | 1991-12-12 | Processo para a preparacao de novos derivados de di-hidroisoquinolina |
Country Status (25)
Country | Link |
---|---|
US (1) | US5177085A (pt) |
EP (1) | EP0490823B1 (pt) |
JP (1) | JPH0764820B2 (pt) |
KR (1) | KR920012040A (pt) |
AT (1) | ATE145201T1 (pt) |
AU (1) | AU643575B2 (pt) |
CA (1) | CA2057524A1 (pt) |
CZ (1) | CZ281669B6 (pt) |
DE (1) | DE69123124T2 (pt) |
DK (1) | DK0490823T3 (pt) |
ES (1) | ES2093694T3 (pt) |
FI (1) | FI915844A (pt) |
GB (1) | GB9027055D0 (pt) |
GR (1) | GR3022034T3 (pt) |
HU (1) | HUT61729A (pt) |
IE (1) | IE914325A1 (pt) |
IL (1) | IL100328A (pt) |
MX (1) | MX9102502A (pt) |
MY (1) | MY129941A (pt) |
NZ (1) | NZ240936A (pt) |
PL (1) | PL168329B1 (pt) |
PT (1) | PT99775B (pt) |
RU (1) | RU2060992C1 (pt) |
TW (1) | TW201736B (pt) |
ZA (1) | ZA919858B (pt) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9212673D0 (en) * | 1992-06-15 | 1992-07-29 | Celltech Ltd | Chemical compounds |
GB9222253D0 (en) * | 1992-10-23 | 1992-12-09 | Celltech Ltd | Chemical compounds |
US5622977A (en) * | 1992-12-23 | 1997-04-22 | Celltech Therapeutics Limited | Tri-substituted (aryl or heteroaryl) derivatives and pharmaceutical compositions containing the same |
GB9226830D0 (en) * | 1992-12-23 | 1993-02-17 | Celltech Ltd | Chemical compounds |
GB9304919D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
GB9304920D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
GB9322828D0 (en) * | 1993-11-05 | 1993-12-22 | Sandoz Ltd | Organic compounds |
GB9326173D0 (en) * | 1993-12-22 | 1994-02-23 | Celltech Ltd | Chemical compounds and process |
ATE260911T1 (de) * | 1993-12-22 | 2004-03-15 | Celltech R&D Ltd | Trisubstituierte phenyl-derivate, verfahren zu deren herstellung und deren verwendung als phosphodiesterase (typ iv) hemmstoffe |
US5786354A (en) * | 1994-06-21 | 1998-07-28 | Celltech Therapeutics, Limited | Tri-substituted phenyl derivatives and processes for their preparation |
US6245774B1 (en) | 1994-06-21 | 2001-06-12 | Celltech Therapeutics Limited | Tri-substituted phenyl or pyridine derivatives |
GB9412571D0 (en) * | 1994-06-22 | 1994-08-10 | Celltech Ltd | Chemical compounds |
GB9412573D0 (en) * | 1994-06-22 | 1994-08-10 | Celltech Ltd | Chemical compounds |
GB9412672D0 (en) * | 1994-06-23 | 1994-08-10 | Celltech Ltd | Chemical compounds |
US5922751A (en) * | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
US5948820A (en) | 1994-08-22 | 1999-09-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzene compound and pharmaceutical use thereof |
DE69524962T4 (de) * | 1994-08-22 | 2003-08-28 | Mitsubishi Pharma Corp., Osaka | Benzolderivate und deren medizinische verwendung |
US6025361A (en) * | 1994-12-13 | 2000-02-15 | Euro-Celtique, S.A. | Trisubstituted thioxanthines |
ATE247655T1 (de) * | 1994-12-13 | 2003-09-15 | Euro Celtique Sa | Dreifachsubstituierte thioxanthine |
US6268373B1 (en) * | 1995-06-07 | 2001-07-31 | Euro-Celtique S.A. | Trisubstituted thioxanthines |
GB9523267D0 (en) * | 1995-11-14 | 1996-01-17 | Sandoz Ltd | Organic compounds |
GB9523675D0 (en) | 1995-11-20 | 1996-01-24 | Celltech Therapeutics Ltd | Chemical compounds |
GB9526246D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
GB9526245D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
GB9526243D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
AU2593997A (en) * | 1996-03-21 | 1997-10-10 | Trustees Of Columbia University In The City Of New York, The | Craf1 (traf-3) isoforms and uses thereof |
US6075016A (en) * | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
GB9608435D0 (en) * | 1996-04-24 | 1996-06-26 | Celltech Therapeutics Ltd | Chemical compounds |
GB9619284D0 (en) * | 1996-09-16 | 1996-10-30 | Celltech Therapeutics Ltd | Chemical compounds |
AU4674797A (en) * | 1996-10-22 | 1998-05-15 | Ortho Pharmaceutical Corporation | Phenylalaninol derivatives for the treatment of central nervous system disorders |
GB9622363D0 (en) * | 1996-10-28 | 1997-01-08 | Celltech Therapeutics Ltd | Chemical compounds |
GB9625184D0 (en) * | 1996-12-04 | 1997-01-22 | Celltech Therapeutics Ltd | Chemical compounds |
ID19155A (id) * | 1996-12-13 | 1998-06-18 | Tanabe Seiyaku Co | Turunan-turunan piridin, pembuatannya dan intermediet untuk pembuatannya |
EP0946523A1 (en) | 1996-12-23 | 1999-10-06 | Celltech Therapeutics Limited | Fused polycyclic 2-aminopyrimidine derivatives, their preparation and their use as protein tyrosine kinase inhibitors |
AU6230098A (en) * | 1997-02-27 | 1998-09-18 | Tanabe Seiyaku Co., Ltd. | Isoquinolinone derivatives, process for preparing the same, and their use as phosphodiesterase inhibitors |
GB9705361D0 (en) * | 1997-03-14 | 1997-04-30 | Celltech Therapeutics Ltd | Chemical compounds |
GB9713087D0 (en) * | 1997-06-20 | 1997-08-27 | Celltech Therapeutics Ltd | Chemical compounds |
PL190685B1 (pl) | 1997-07-25 | 2005-12-30 | Altana Pharma Ag | Nowe pochodne tetrazolu, środek farmaceutyczny oraz zastosowanie |
JP2001518468A (ja) * | 1997-09-30 | 2001-10-16 | モレキュラー デザインズ インターナショナル,インコーポレイテッド | β3アドレナリン受容体拮抗薬、拮抗薬合成物およびこれらの応用方法 |
IT1296985B1 (it) | 1997-12-19 | 1999-08-03 | Zambon Spa | Derivati benzazinici inibitori della fosfodiesterasi 4 |
IT1302677B1 (it) | 1998-10-15 | 2000-09-29 | Zambon Spa | Derivati benzazinici inibitori della fosfodiesterasi 4 |
GB9914258D0 (en) * | 1999-06-18 | 1999-08-18 | Celltech Therapeutics Ltd | Chemical compounds |
MXPA02001830A (es) | 1999-08-21 | 2002-08-12 | Byk Gulden Lomberg Chem Fab | Combinacion sinergica de inhibidores de pde y agonista de beta 2 adrenoceptor. |
GB9924862D0 (en) * | 1999-10-20 | 1999-12-22 | Celltech Therapeutics Ltd | Chemical compounds |
US6924292B2 (en) * | 2000-03-23 | 2005-08-02 | Takeda Chemical Industries, Ltd. | Furoisoquinoline derivatives, process for producing the same and use thereof |
SK5782003A3 (en) | 2000-11-14 | 2003-10-07 | Altana Pharma Ag | 3,4-Dihydroisoquinoline and isoquinoline compounds, pharmaceutical composition comprising the same and their use |
AU2002224835A1 (en) * | 2000-11-14 | 2002-05-27 | Byk Gulden Lomberg Chemische Fabrik G.M.B.H. | Dihydroisoquinolines as novel phosphodiesterase inhibitors |
US6593341B2 (en) | 2001-03-29 | 2003-07-15 | Molecular Design International, Inc. | β3-adrenoreceptor agonists, agonist compositions and methods of making and using the same |
RU2330024C2 (ru) * | 2001-05-29 | 2008-07-27 | Шеринг Акциенгезельшафт | Ингибирующие cdk-киназы пиримидины, способ их получения и их применение в качестве лекарственных средств |
AU2003202495B2 (en) * | 2002-01-11 | 2006-07-20 | Sankyo Company, Limited | Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these |
US7745180B2 (en) * | 2002-04-24 | 2010-06-29 | Hitachi Chemical Co., Ltd. | Device and method for high-throughput quantification of mRNA from whole blood |
AU2003263216A1 (en) * | 2002-08-17 | 2004-03-11 | Nycomed Gmbh | Benzonaphthyridines with PDE 3/4 inhibiting activity |
PL374014A1 (en) * | 2002-08-17 | 2005-09-19 | Altana Pharma Ag | Novel phenanthridines having pde 3/4 inhibiting properties |
EP1539164B1 (en) | 2002-08-29 | 2006-12-20 | ALTANA Pharma AG | 2-hydroxy-6-phenylphenanthridines as pde-4 inhibitors |
JP4587295B2 (ja) | 2002-08-29 | 2010-11-24 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | Pde4インヒビターとしての3−ヒドロキシ−6−フェニルフェナントリジン |
US6596734B1 (en) | 2002-10-11 | 2003-07-22 | Molecular Design International, Inc. | Tetrahydroisoquinoline compounds for use as β3-adrenoreceptor agonists |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
EA200501548A1 (ru) | 2003-04-01 | 2006-02-24 | Апплайд Резеч Системз Арс Холдинг Н.В. | Ингибиторы фосфодиэстераз при бесплодии |
CA2556086C (en) | 2004-02-18 | 2014-04-01 | Altana Pharma Ag | Novel guanidinyl-substituted hydroxy-6-phenylphenenthridines as effective phosphodiesterase (pde) 4 inhibitors |
NZ549162A (en) | 2004-02-24 | 2009-12-24 | Sankyo Co | Amino-pyrrol alcohol compounds |
RS53543B1 (en) | 2004-03-03 | 2015-02-27 | Takeda Gmbh | NEW HYDROXY-6-HETEROARYLPHENANTRIDINES AND THEIR USE AS PDE4 INHIBITORS |
ATE450524T1 (de) | 2005-03-02 | 2009-12-15 | Nycomed Gmbh | (2r,4ar,10br)-6-(2,6-dimethoxypyridin-3-yl)-9- ethoxy-8-methoxy-1,2,3,4,4a,10b- hexahydrophenanthridin-2-ol hydrochloridsalz |
DK2170930T3 (da) | 2007-06-04 | 2012-11-05 | Synergy Pharmaceuticals Inc | Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
ES2664873T3 (es) | 2011-03-01 | 2018-04-23 | Synergy Pharmaceuticals Inc. | Proceso de preparación de agonistas de guanilato ciclasa C |
EP2958577A2 (en) | 2013-02-25 | 2015-12-30 | Synergy Pharmaceuticals Inc. | Guanylate cyclase receptor agonists for use in colonic cleansing |
US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
KR102272746B1 (ko) | 2013-06-05 | 2021-07-08 | 보슈 헬스 아일랜드 리미티드 | 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법 |
KR20220147691A (ko) | 2013-08-09 | 2022-11-03 | 알데릭스, 인코포레이티드 | 인산염 수송을 억제하기 위한 화합물 및 방법 |
WO2015022418A1 (en) | 2013-08-16 | 2015-02-19 | Takeda Gmbh | Treatment of cognitive impairment with pde4 inhibitor |
JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス, インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1400425A (en) * | 1971-09-22 | 1975-07-16 | Rolland Sa A | Substituted 3-hydroxymethyl-isoquinolines and derivatives |
PH25651A (en) * | 1986-05-21 | 1991-08-21 | Duphar Int Res | New di, tetrahydroisoquinoline derivatives |
HU196758B (en) * | 1986-05-21 | 1989-01-30 | Gyogyszerkutato Intezet | Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them |
GB8800397D0 (en) * | 1988-01-08 | 1988-02-10 | Sandoz Ltd | Improvements in/relating to organic compounds |
-
1990
- 1990-12-13 GB GB909027055A patent/GB9027055D0/en active Pending
-
1991
- 1991-12-02 HU HU913760A patent/HUT61729A/hu unknown
- 1991-12-09 DE DE69123124T patent/DE69123124T2/de not_active Expired - Fee Related
- 1991-12-09 ES ES91810954T patent/ES2093694T3/es not_active Expired - Lifetime
- 1991-12-09 EP EP91810954A patent/EP0490823B1/en not_active Expired - Lifetime
- 1991-12-09 AT AT91810954T patent/ATE145201T1/de not_active IP Right Cessation
- 1991-12-09 DK DK91810954.7T patent/DK0490823T3/da active
- 1991-12-10 MY MYPI91002283A patent/MY129941A/en unknown
- 1991-12-11 FI FI915844A patent/FI915844A/fi not_active Application Discontinuation
- 1991-12-11 AU AU88985/91A patent/AU643575B2/en not_active Ceased
- 1991-12-11 MX MX9102502A patent/MX9102502A/es unknown
- 1991-12-11 NZ NZ240936A patent/NZ240936A/xx unknown
- 1991-12-11 IL IL10032891A patent/IL100328A/en not_active IP Right Cessation
- 1991-12-11 CZ CS913757A patent/CZ281669B6/cs unknown
- 1991-12-12 US US07/805,662 patent/US5177085A/en not_active Expired - Fee Related
- 1991-12-12 IE IE432591A patent/IE914325A1/en unknown
- 1991-12-12 RU SU915010401A patent/RU2060992C1/ru active
- 1991-12-12 KR KR1019910022728A patent/KR920012040A/ko not_active Application Discontinuation
- 1991-12-12 PL PL91292738A patent/PL168329B1/pl unknown
- 1991-12-12 JP JP3328665A patent/JPH0764820B2/ja not_active Expired - Lifetime
- 1991-12-12 CA CA002057524A patent/CA2057524A1/en not_active Abandoned
- 1991-12-12 PT PT99775A patent/PT99775B/pt not_active IP Right Cessation
- 1991-12-13 TW TW080109769A patent/TW201736B/zh active
- 1991-12-13 ZA ZA919858A patent/ZA919858B/xx unknown
-
1996
- 1996-12-13 GR GR960403459T patent/GR3022034T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
KR920012040A (ko) | 1992-07-25 |
DE69123124T2 (de) | 1997-05-15 |
AU643575B2 (en) | 1993-11-18 |
GR3022034T3 (en) | 1997-03-31 |
IL100328A0 (en) | 1992-09-06 |
ES2093694T3 (es) | 1997-01-01 |
ATE145201T1 (de) | 1996-11-15 |
CZ281669B6 (cs) | 1996-12-11 |
AU8898591A (en) | 1992-06-18 |
CS375791A3 (en) | 1992-06-17 |
CA2057524A1 (en) | 1992-06-14 |
FI915844A (fi) | 1992-06-14 |
ZA919858B (en) | 1993-06-14 |
MX9102502A (es) | 1992-06-01 |
TW201736B (pt) | 1993-03-11 |
HUT61729A (en) | 1993-03-01 |
US5177085A (en) | 1993-01-05 |
RU2060992C1 (ru) | 1996-05-27 |
JPH04275276A (ja) | 1992-09-30 |
NZ240936A (en) | 1993-09-27 |
DE69123124D1 (de) | 1996-12-19 |
PL168329B1 (pl) | 1996-02-29 |
FI915844A0 (fi) | 1991-12-11 |
EP0490823B1 (en) | 1996-11-13 |
IL100328A (en) | 1995-12-08 |
DK0490823T3 (pt) | 1997-02-17 |
HU913760D0 (en) | 1992-02-28 |
PL292738A1 (en) | 1992-12-14 |
IE914325A1 (en) | 1992-06-17 |
MY129941A (en) | 2007-05-31 |
GB9027055D0 (en) | 1991-02-06 |
EP0490823A1 (en) | 1992-06-17 |
PT99775B (pt) | 1999-05-31 |
JPH0764820B2 (ja) | 1995-07-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT99775A (pt) | Processo para a preparacao de novos derivados de di-hidroisoquinolina | |
ES2040261T3 (es) | Procedimiento para preparar acidos 6-fluor-4-oxo-1,4-dihidroquinolina-3-carboxilicos sustituidos y acidos 9-fluor-3-metil-7-oxo-2,3-dihidro-7h-pirido(1,2,3-de)(1,4)benzoxazina-6-carboxilico sustituidos. | |
DK0423714T3 (da) | Hårrevitaliseringsmiddel | |
PT82610B (pt) | Processo para a preparacao de tiazolidino-dionas hipoglicemicas | |
NO2004004I1 (no) | Bortezomib eller en farmasøytisk akseptabel ester derav, eventuelt i form av et farmasøytisk akseptabelt salt derav | |
PT94085A (pt) | Processo para a preparacao de derivados de amino-fenol anti-inflamatorios | |
ES2105362T3 (es) | Nuevos derivados de acidos quinolon- y naftiridoncarboxilicos. | |
SE8600017D0 (sv) | New compound | |
NO301767B1 (no) | Salt av clavulansyre | |
SE9300758D0 (sv) | Process for the production of clavulanic acid | |
PT92952A (pt) | Processo para a preparacao de acidos 3-fenil-5,6-di-hidrobenz { c }acridina-7- carboxilicos, de compostos relacionados e de composicoes farmaceuticas que os contem | |
PT93450A (pt) | Processo para a preparacao de novos derivados azetidinicos de acidos piridinocarboxilicos e de composicoes farmaceuticas que os contem | |
PT82550B (pt) | Processo de preparacao de derivados de 1,3-oxatiano e de composicoes farmaceuticas que os contem | |
PT87563A (pt) | Process for the preparation of vinylcephalosporins useful as medicaments | |
PT95519A (pt) | Processo para a preparacao de derivados de 1,4-di-hidro-4-oxo-3-quinolina uteiscomo agentes antibacterianos selectivos em mamiferos | |
IT1229846B (it) | Esteri di catecolammine. | |
ATE3112T1 (de) | 1-benzylierte ergometrinderivate, verfahren zu ihrer herstellung sowie diese enthaltende pharmazeutische zusammensetzungen. | |
ATE129244T1 (de) | 4-((thiophen-2-carbonyl)oxy>pyrrolidin-2- carbonsäure, deren herstellung und deren verwendung als entzündungshemmendes und wundheilendes mittel. | |
ES2052812T3 (es) | Un procedimiento para la preparacion de derivados de pirrolizina. | |
ATA452779A (de) | Verfahren zur herstellung von neuen 4,5,6,7- tetrahydro-2h-benzo(c)pyrrolderivaten und ihren pharmazeutisch annehmbaren saeureadditionssalzen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19920707 |
|
FG3A | Patent granted, date of granting |
Effective date: 19990222 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20000831 |