HUP0303037A2 - Alzheimer-kór kezelésére alkalmas vegyületek és ezeket tartalmazó gyógyszerkészítmények - Google Patents

Alzheimer-kór kezelésére alkalmas vegyületek és ezeket tartalmazó gyógyszerkészítmények

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Publication number
HUP0303037A2
HUP0303037A2 HU0303037A HUP0303037A HUP0303037A2 HU P0303037 A2 HUP0303037 A2 HU P0303037A2 HU 0303037 A HU0303037 A HU 0303037A HU P0303037 A HUP0303037 A HU P0303037A HU P0303037 A2 HUP0303037 A2 HU P0303037A2
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HU
Hungary
Prior art keywords
optionally substituted
group
optionally
heteroaryl
aryl
Prior art date
Application number
HU0303037A
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English (en)
Inventor
James P. Beck
Lawrence Y. Fang
John N. Freskos
Andrea Gailunas
Roy Hom
Barbara Jagodzinska
Michel Maillard
Shon R. Pulley
Ruth E. Tenbrink
John Varghese
Original Assignee
Elan Pharmaceuticals, Inc.
Pharmacia & Upjohn Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharmaceuticals, Inc., Pharmacia & Upjohn Co. filed Critical Elan Pharmaceuticals, Inc.
Publication of HU0303037D0 publication Critical patent/HU0303037D0/hu
Publication of HUP0303037A2 publication Critical patent/HUP0303037A2/hu
Publication of HUP0303037A3 publication Critical patent/HUP0303037A3/hu

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Abstract

A találmány szerinti vegyületek (X) és (X') általános képletében Rljelentése adott esetben szubsztituált és adott esetben S, SO vagy SO2csoporttal megszakított alkilcsoport, adott esetben szubsztituáltalkenil- vagy alkinilcsoport, vagy adott esetben szubsztituált ésadott esetben alkilénláncon keresztül kapcsolódó aril-, heteroaril-vagy heterociklusos csoport, R2 jelentése hidrogénatom, adott esetbenszubsztituált alkil-, alkenil- vagy alkinilcsoport, vagy adott esetbenszubsztituált és adott esetben alkilénláncon keresztül kapcsolódóaril-, heteroaril-, heterociklusos vagy cikloalkilcsoport, R3jelentése hidrogénatom, adott esetben szubsztituált alkilcsoport,alkenil- vagy alkinilcsoport, vagy adott esetben szubsztituált ésadott esetben alkilénláncon keresztül kapcsolódó aril-, heteroaril-vagy cikloalkilcsoport, vagy R2 és R3 jelentése a kapcsolódószénatommal együtt adott esetben heteroatomot vagy csoportottartalmazó gyűrű, RC jelentése adott esetben szubsztituáltalkilcsoport, vagy adott esetben szubsztituált és adott esetbenalkilénláncon keresztül kapcsolódó aril-, heteroaril-, heterociklusosvagy cikloalkilcsoport, RN jelentése adott esetben szubsztituált ésadott esetben CO, SO2 és/vagy alkilénláncon keresztül kapcsolódóaril-, heteroaril-, heterociklusos, alkil- vagy cikloalkilcsoport, Ajelentése adott esetben szubsztituált fenil- vagy nafilcsoport. Atalálmány szerinti vegyületek felhasználhatók Alzheimer-kór és hasonlóbetegségek kezelésére. A találmány kiterjed a vegyületeket tartalmazógyógyszerkészítményekre. Ó
HU0303037A 2000-06-30 2001-06-29 Compounds to treat alzheimer's disease and pharmaceutical compositions containing them HUP0303037A3 (en)

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AU2001273137A1 (en) 2002-01-14
NZ522899A (en) 2005-06-24
KR20030058960A (ko) 2003-07-07
BR0112000A (pt) 2003-06-03
NO20026199D0 (no) 2002-12-23
WO2002002512A2 (en) 2002-01-10
NZ538542A (en) 2006-09-29
HUP0303037A3 (en) 2006-02-28
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HU0303037D0 (en) 2003-11-28
NO20026199L (no) 2003-02-21
US20020128255A1 (en) 2002-09-12
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EP1353898A2 (en) 2003-10-22
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UY26813A1 (es) 2002-01-31
US7214715B2 (en) 2007-05-08
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