HUP0300853A2 - Kemény kapszula - Google Patents
Kemény kapszulaInfo
- Publication number
- HUP0300853A2 HUP0300853A2 HU0300853A HUP0300853A HUP0300853A2 HU P0300853 A2 HUP0300853 A2 HU P0300853A2 HU 0300853 A HU0300853 A HU 0300853A HU P0300853 A HUP0300853 A HU P0300853A HU P0300853 A2 HUP0300853 A2 HU P0300853A2
- Authority
- HU
- Hungary
- Prior art keywords
- hard capsule
- fatty acid
- polyoxyethylene
- hard
- copolymerization
- Prior art date
Links
- 239000007902 hard capsule Substances 0.000 title abstract 4
- -1 poly(vinyl alcohol) Polymers 0.000 abstract 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 238000007334 copolymerization reaction Methods 0.000 abstract 1
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical class OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000006116 polymerization reaction Methods 0.000 abstract 1
- 229920002451 polyvinyl alcohol Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
- Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Polymerisation Methods In General (AREA)
- Graft Or Block Polymers (AREA)
Abstract
A találmány kemény kapszulára vonatkozik, amelyet főként le- galábbegy polimerizálható vinil monomer poli(vinil-alkohol) és/vagy annakegy származéka jelenlétében végzett polimerizálásával vagykopolimerizálásával kapott polimerből vagy kopolimerből állítanak elő.A hagyományos kemény kapszuláktól eltérően ez a kemény kapszulaoldószerrel, például polietilénglikollal, polioxietilén-szorbitón-zsírsav-észterrel, 6-12 szénatomos zsírsavval vagy sójával,polioxietilén-ricinusolajjal, dietilénglikolszármazékkal tölthető anehezen oldható hatóanyagok oldódásának elősegítésére. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000259830 | 2000-08-29 | ||
PCT/JP2001/007244 WO2002017848A1 (en) | 2000-08-29 | 2001-08-24 | Hard capsule |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0300853A2 true HUP0300853A2 (hu) | 2003-10-28 |
HUP0300853A3 HUP0300853A3 (en) | 2006-07-28 |
Family
ID=18747950
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0300853A HUP0300853A3 (en) | 2000-08-29 | 2001-08-24 | Hard capsule |
Country Status (15)
Country | Link |
---|---|
US (2) | US6967026B2 (hu) |
EP (1) | EP1323404B1 (hu) |
JP (1) | JP4596732B2 (hu) |
KR (1) | KR100829474B1 (hu) |
CN (1) | CN1209091C (hu) |
AU (2) | AU8013801A (hu) |
BR (1) | BR0113570A (hu) |
CA (1) | CA2419825C (hu) |
ES (1) | ES2437791T3 (hu) |
HU (1) | HUP0300853A3 (hu) |
MX (1) | MXPA03001854A (hu) |
RU (1) | RU2003108732A (hu) |
TW (1) | TWI249411B (hu) |
WO (1) | WO2002017848A1 (hu) |
ZA (1) | ZA200301319B (hu) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0005016D0 (en) * | 2000-03-01 | 2000-04-26 | Jumik Technologies Limited | PVA-Containing compositions |
US8802139B2 (en) | 2003-06-26 | 2014-08-12 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
WO2005000279A1 (ja) * | 2003-06-27 | 2005-01-06 | Wakunaga Pharmaceutical Co., Ltd. | 硬カプセル剤 |
WO2005019286A1 (ja) * | 2003-08-20 | 2005-03-03 | Shionogi & Co., Ltd. | 新規コーティング組成物 |
DE10358799A1 (de) * | 2003-12-12 | 2005-07-14 | Basf Ag | Verwendung von wasserdispergierbaren Copolymerisaten von Hydroxyalkyl(meth)acrylaten zur Herstellung von Hartkapseln |
JPWO2005113010A1 (ja) * | 2004-05-24 | 2008-07-31 | クオリカプス株式会社 | 表面改質および溶解性が改善された硬カプセル |
US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
JPWO2006070578A1 (ja) * | 2004-12-28 | 2008-06-12 | クオリカプス株式会社 | 硬カプセルのバンドシール |
JPWO2006106799A1 (ja) * | 2005-03-31 | 2008-09-11 | 塩野義製薬株式会社 | ポリビニルアルコール共重合体を用いたマイクロカプセル |
JP2007091670A (ja) * | 2005-09-29 | 2007-04-12 | Shionogi & Co Ltd | 退色が抑制された着色カプセル |
US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
DK1993559T3 (en) | 2006-02-03 | 2016-10-03 | Opko Renal Llc | Treatment of vitamin D deficiency and MALFUNCTION with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 |
JP2007230948A (ja) * | 2006-03-02 | 2007-09-13 | Univ Meijo | 腸溶性化硬カプセル |
WO2007112581A1 (en) | 2006-04-03 | 2007-10-11 | Isa Odidi | Controlled release delivery device comprising an organosol coat |
KR100721431B1 (ko) * | 2006-04-19 | 2007-05-25 | 학교법인 포항공과대학교 | 고분자 캡슐 및 그 제조방법 |
US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
EP2057985B1 (en) | 2006-06-13 | 2013-10-16 | Nippon Shinyaku Co., Ltd. | Tablet coated with a polyvinyl alcohol copolymer |
ES2670029T3 (es) | 2006-06-21 | 2018-05-29 | Opko Ireland Global Holdings, Ltd. | Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D |
WO2008018825A1 (en) * | 2006-08-10 | 2008-02-14 | Astrazeneca Ab | Oral polyvinyl alcohol capsules comprising proton pump inhibitors |
ES2605962T3 (es) | 2007-02-15 | 2017-03-17 | Qualicaps Co., Ltd. | Elemento de sellado en banda para una cápsula dura llena de PEG |
JP5140804B2 (ja) * | 2007-02-27 | 2013-02-13 | 国立大学法人広島大学 | 生体再生カプセル |
EP2140883B1 (en) | 2007-04-20 | 2012-10-31 | Daido Chemical Corporation | Novel base for dry solid dispersion, solid dispersion containing the base, and composition containing the dispersion |
KR101495578B1 (ko) | 2007-04-25 | 2015-02-25 | 사이토크로마 인코포레이티드 | 비타민 d 부족 및 결핍의 치료 방법 |
EP3225243A1 (en) | 2007-04-25 | 2017-10-04 | Opko Renal, LLC | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
DK2481400T3 (da) | 2007-04-25 | 2014-09-29 | Opko Ip Holdings Ii Inc | Orale præparater med kontrolleret frigivelse omfattende en vitamin D-forbindelse og en voksagtig bærer |
ES2954932T3 (es) | 2008-04-02 | 2023-11-27 | Eirgen Pharma Ltd | Métodos, composiciones, usos y kits útiles para la deficiencia de vitamina D y trastornos relacionados |
JP5289429B2 (ja) * | 2008-04-10 | 2013-09-11 | クオリカプス株式会社 | 硬質カプセル剤 |
WO2009125485A1 (ja) * | 2008-04-10 | 2009-10-15 | クオリカプス株式会社 | 硬質カプセル剤 |
WO2009128433A1 (ja) | 2008-04-15 | 2009-10-22 | 塩野義製薬株式会社 | フィルム状組成物 |
JP5498387B2 (ja) | 2008-09-12 | 2014-05-21 | 第一三共ヘルスケア株式会社 | 変色が抑制された安定な医薬製剤 |
IT1393524B1 (it) * | 2009-01-30 | 2012-04-27 | Altergon Sa | Contenitore per uso farmaceutico atto al rilascio quantitativo di una monodose per somministrazione orale di ormoni tiroidei t3 e t4 in soluzione |
JPWO2010093020A1 (ja) | 2009-02-13 | 2012-08-16 | 日新化成株式会社 | 硬カプセル |
CN102369022A (zh) * | 2009-04-03 | 2012-03-07 | 日新化成株式会社 | 硬胶囊 |
CN102470177A (zh) * | 2009-08-31 | 2012-05-23 | 日新化成株式会社 | 包衣用组合物 |
JP5705206B2 (ja) * | 2010-02-26 | 2015-04-22 | 日新化成株式会社 | 硬カプセルおよびその製造方法 |
CN105796530A (zh) | 2010-03-29 | 2016-07-27 | 赛特克罗公司 | 用于降低甲状旁腺水平的方法和组合物 |
KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
SI2946774T1 (sl) * | 2014-05-19 | 2020-07-31 | Tillotts Pharma Ag | Obložene kapsule s prirejenim sproščanjem |
CA2910865C (en) | 2014-07-15 | 2016-11-29 | Isa Odidi | Compositions and methods for reducing overdose |
US10220047B2 (en) | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
CN104530320B (zh) * | 2014-12-26 | 2017-06-23 | 中科院广州化学有限公司 | 一种丙烯酸接枝聚乙烯醇增强剂及其制备方法和应用 |
JP6646469B2 (ja) * | 2015-02-23 | 2020-02-14 | 株式会社Nbcメッシュテック | 抗ウイルス性を有する吸水性高分子 |
IL290855B2 (en) | 2016-03-28 | 2024-06-01 | Eirgen Pharma Ltd | Treatment methods using vitamin D |
EP3485911A4 (en) | 2016-07-06 | 2020-02-19 | Qualicaps Co., Ltd. | HARD CAPSULE WITH IMPROVED HARDNESS AND MANUFACTURING METHOD THEREOF |
JP7174383B2 (ja) * | 2017-06-09 | 2022-11-17 | 富士カプセル株式会社 | シームレスカプセル皮膜用組成物及びシームレスカプセル |
US20210369625A1 (en) | 2018-10-02 | 2021-12-02 | Qualicaps Co., Ltd. | Improved-strength hard capsule and production method for same |
WO2020071393A1 (ja) | 2018-10-02 | 2020-04-09 | クオリカプス株式会社 | 強度が改善された硬質カプセル、及びその製造方法 |
CN109060540A (zh) * | 2018-10-11 | 2018-12-21 | 湖北中烟工业有限责任公司 | 一种烟用爆珠表面压陷值的检测装置 |
CN113447356B (zh) * | 2021-07-12 | 2022-02-18 | 广州白云山星群(药业)股份有限公司 | 一种软胶囊囊皮机械性能测试方法及设备 |
CN113999668B (zh) * | 2021-08-18 | 2023-12-19 | 江苏集萃先进高分子材料研究所有限公司 | 一种不可逆变色微胶囊及其制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3300546A (en) * | 1965-10-05 | 1967-01-24 | American Cyanamid Co | Water soluble envelope prepared from a graft polymer of alkyl acrylate on a polyvinyl alcohol/polyvinyl acetate co-polymer |
US3630955A (en) * | 1968-01-29 | 1971-12-28 | Ncr Co | Graft polymerization as a capsule wall treating process |
DE2363853A1 (de) * | 1973-12-21 | 1975-07-03 | Hoechst Ag | Selbsttragende packungen oder kapseln zum umhuellen von medikamenten |
JPS5586463A (en) * | 1978-12-22 | 1980-06-30 | Shinetsu Chemical Co | Enteric coating hard capsule |
JPS6176413A (ja) * | 1984-09-21 | 1986-04-18 | Junzo Sunamoto | 吸水性高分子によりカプセル化されたリポソ−ムの製造法 |
GB2214918B (en) * | 1988-02-03 | 1992-10-07 | Warner Lambert Co | Polymeric materials made from starch and at least one synthetic thermoplastic polymeric material |
US5095054A (en) * | 1988-02-03 | 1992-03-10 | Warner-Lambert Company | Polymer compositions containing destructurized starch |
US5281356A (en) * | 1993-03-25 | 1994-01-25 | Lever Brothers Company | Heavy duty liquid detergent compositions containing non-proteolytic enzymes comprising capsules comprising proteolytic enzyme and composite polymer |
US5424265A (en) * | 1993-06-15 | 1995-06-13 | Safetec Of America | Capsule for absorbing liquid waste in a suction canister |
JPH09216818A (ja) * | 1995-12-04 | 1997-08-19 | Kyowa Hakko Kogyo Co Ltd | 硬カプセル剤 |
DE69937549T2 (de) | 1998-03-11 | 2008-09-04 | Warner-Lambert Company Llc | Polyvinylalkohol-zusammensetzungen |
EP1124541B1 (de) * | 1998-09-30 | 2003-11-26 | Basf Aktiengesellschaft | Verwendung von wasserlöslichen oder wasserdispergierbaren polyether-haltigen pfropfpolymerisaten als überzugsmittel, bindemittel und/oder filmbildender hilfsstoff in pharmazeutischen darreichungsformen |
DE19932144A1 (de) * | 1999-07-09 | 2001-01-11 | Basf Ag | Mikrokapselzubereitungen und Mikrokapseln enthaltende Wasch- und Reinigungsmittel |
JP2001170137A (ja) | 1999-12-16 | 2001-06-26 | Shionogi Qualicaps Kk | 硬質カプセル及びその製造方法 |
-
2001
- 2001-08-24 MX MXPA03001854A patent/MXPA03001854A/es unknown
- 2001-08-24 CN CNB018147372A patent/CN1209091C/zh not_active Expired - Fee Related
- 2001-08-24 CA CA2419825A patent/CA2419825C/en not_active Expired - Fee Related
- 2001-08-24 JP JP2002522823A patent/JP4596732B2/ja not_active Expired - Fee Related
- 2001-08-24 HU HU0300853A patent/HUP0300853A3/hu unknown
- 2001-08-24 RU RU2003108732/15A patent/RU2003108732A/ru not_active Application Discontinuation
- 2001-08-24 WO PCT/JP2001/007244 patent/WO2002017848A1/ja active IP Right Grant
- 2001-08-24 BR BR0113570-8A patent/BR0113570A/pt not_active Application Discontinuation
- 2001-08-24 ES ES01958454.9T patent/ES2437791T3/es not_active Expired - Lifetime
- 2001-08-24 AU AU8013801A patent/AU8013801A/xx active Pending
- 2001-08-24 AU AU2001280138A patent/AU2001280138B2/en not_active Ceased
- 2001-08-24 KR KR1020037002968A patent/KR100829474B1/ko not_active IP Right Cessation
- 2001-08-24 US US10/362,114 patent/US6967026B2/en not_active Expired - Fee Related
- 2001-08-24 EP EP01958454.9A patent/EP1323404B1/en not_active Expired - Lifetime
- 2001-08-28 TW TW090121157A patent/TWI249411B/zh not_active IP Right Cessation
-
2003
- 2003-02-18 ZA ZA200301319A patent/ZA200301319B/en unknown
-
2005
- 2005-04-20 US US11/110,428 patent/US20050186268A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MXPA03001854A (es) | 2004-12-03 |
AU2001280138B2 (en) | 2006-03-16 |
EP1323404A8 (en) | 2004-02-25 |
US6967026B2 (en) | 2005-11-22 |
BR0113570A (pt) | 2004-07-06 |
TWI249411B (en) | 2006-02-21 |
CA2419825A1 (en) | 2003-02-18 |
AU8013801A (en) | 2002-03-13 |
KR100829474B1 (ko) | 2008-05-16 |
CN1449272A (zh) | 2003-10-15 |
RU2003108732A (ru) | 2004-07-27 |
WO2002017848A1 (en) | 2002-03-07 |
ZA200301319B (en) | 2004-02-10 |
EP1323404A1 (en) | 2003-07-02 |
ES2437791T3 (es) | 2014-01-14 |
CN1209091C (zh) | 2005-07-06 |
JP4596732B2 (ja) | 2010-12-15 |
EP1323404B1 (en) | 2013-10-16 |
CA2419825C (en) | 2010-05-25 |
US20050186268A1 (en) | 2005-08-25 |
EP1323404A4 (en) | 2005-06-22 |
US20030166763A1 (en) | 2003-09-04 |
KR20030026358A (ko) | 2003-03-31 |
HUP0300853A3 (en) | 2006-07-28 |
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