HUP0100095A2 - Kettős kapszula hatóanyagok adagolására többhatóanyagos terápiában - Google Patents
Kettős kapszula hatóanyagok adagolására többhatóanyagos terápiábanInfo
- Publication number
- HUP0100095A2 HUP0100095A2 HU0100095A HUP0100095A HUP0100095A2 HU P0100095 A2 HUP0100095 A2 HU P0100095A2 HU 0100095 A HU0100095 A HU 0100095A HU P0100095 A HUP0100095 A HU P0100095A HU P0100095 A2 HUP0100095 A2 HU P0100095A2
- Authority
- HU
- Hungary
- Prior art keywords
- capsule
- active
- administration
- dosage form
- double
- Prior art date
Links
- 239000002775 capsule Substances 0.000 title abstract 7
- 238000002560 therapeutic procedure Methods 0.000 title abstract 4
- 239000002552 dosage form Substances 0.000 abstract 3
- 241000590002 Helicobacter pylori Species 0.000 abstract 2
- 229940037467 helicobacter pylori Drugs 0.000 abstract 2
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 abstract 1
- 239000004098 Tetracycline Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229960004645 bismuth subcitrate Drugs 0.000 abstract 1
- ZQUAVILLCXTKTF-UHFFFAOYSA-H bismuth;tripotassium;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [K+].[K+].[K+].[Bi+3].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O ZQUAVILLCXTKTF-UHFFFAOYSA-H 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000008029 eradication Effects 0.000 abstract 1
- 210000002425 internal capsule Anatomy 0.000 abstract 1
- 229960000282 metronidazole Drugs 0.000 abstract 1
- VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 229960000381 omeprazole Drugs 0.000 abstract 1
- 229960002180 tetracycline Drugs 0.000 abstract 1
- 229930101283 tetracycline Natural products 0.000 abstract 1
- 235000019364 tetracycline Nutrition 0.000 abstract 1
- 150000003522 tetracyclines Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
A találmány tárgya olyan gyógyszeradagoló forma, amely különösenalkalmas hatóanyagoknak az adagolására több hatóanyagos terápiáseljárásokban. Ez a gyógyszeradagoló forma kettős kapszula, ahol egybelső kapszulát egy külső kapszulába helyeznek. Mind a külső, mind abelső kapszula egy vagy több hatóanyagot tartalmaz. Egy találmányszerinti kettős kapszula előnyösen alkalmazható három hatóanyagos vagynégy hatóanyagos terápiában a Helicobacter pylori mikroorganizmusokellen. A találmány egyik előnyös kiviteli formájában agyógyszeradagoló forma áll egy külső kapszulából, amely bizmut-szubcitrátot és metronidazolt tartalmaz; valamint egy belsőkapszulából, amely tetraciklint és adott esetben omeprazolt tartalmaz,melyet a Helicobacter pylori kiirtását eredményező terápiábanalkalmaznak. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT97MI002788A IT1296980B1 (it) | 1997-12-17 | 1997-12-17 | Capsula doppia come forma farmaceutica per la somministrazione di principi attivi in terapie multiple |
PCT/EP1998/008167 WO1999030693A2 (en) | 1997-12-17 | 1998-12-14 | A double capsule for the administration of active principles in multiple therapies |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0100095A2 true HUP0100095A2 (hu) | 2001-06-28 |
HUP0100095A3 HUP0100095A3 (en) | 2001-12-28 |
HU225690B1 HU225690B1 (en) | 2007-06-28 |
Family
ID=11378381
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0100095A HU225690B1 (en) | 1997-12-17 | 1998-12-14 | A double capsule for the administration of active principles in multiple therapies |
Country Status (26)
Country | Link |
---|---|
US (1) | US6350468B1 (hu) |
EP (1) | EP1037614B1 (hu) |
JP (1) | JP4615713B2 (hu) |
KR (1) | KR100509351B1 (hu) |
CN (1) | CN1147292C (hu) |
AR (1) | AR014126A1 (hu) |
AT (1) | ATE254910T1 (hu) |
AU (1) | AU743090B2 (hu) |
BR (1) | BR9812803A (hu) |
CA (1) | CA2315408C (hu) |
CZ (1) | CZ299181B6 (hu) |
DE (1) | DE69820108T2 (hu) |
DK (1) | DK1037614T3 (hu) |
ES (1) | ES2212391T3 (hu) |
HK (1) | HK1034897A1 (hu) |
HU (1) | HU225690B1 (hu) |
ID (1) | ID26340A (hu) |
IT (1) | IT1296980B1 (hu) |
MY (1) | MY121713A (hu) |
NO (1) | NO329126B1 (hu) |
NZ (1) | NZ505655A (hu) |
PE (1) | PE20000512A1 (hu) |
PL (1) | PL192541B1 (hu) |
PT (1) | PT1037614E (hu) |
TR (1) | TR200001761T2 (hu) |
WO (1) | WO1999030693A2 (hu) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
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US6428809B1 (en) | 1999-08-18 | 2002-08-06 | Microdose Technologies, Inc. | Metering and packaging of controlled release medication |
WO2002007710A2 (en) * | 2000-07-20 | 2002-01-31 | Mw Encap Limited | Delivery device |
GB0017673D0 (en) * | 2000-07-20 | 2000-09-06 | Mw Encap Limited | Delivery device |
US20040131670A1 (en) * | 2001-04-17 | 2004-07-08 | Ping Gao | Pellicle-resistant gelatin capsule |
US20040105885A1 (en) * | 2001-04-17 | 2004-06-03 | Ping Gao | Gelatin capsule exhibiting reduced cross-linking |
US20040105883A1 (en) * | 2001-04-17 | 2004-06-03 | Ping Gao | Pharmaceutical dosage form capable of maintaining stable dissolution profile upon storage |
US20070087048A1 (en) * | 2001-05-31 | 2007-04-19 | Abrams Andrew L | Oral dosage combination pharmaceutical packaging |
US6726809B2 (en) * | 2001-09-26 | 2004-04-27 | Albany International Corp. | Industrial process fabric |
US7670612B2 (en) * | 2002-04-10 | 2010-03-02 | Innercap Technologies, Inc. | Multi-phase, multi-compartment capsular delivery apparatus and methods for using same |
AU2003290377A1 (en) * | 2003-01-03 | 2004-07-29 | Marton Milankovits | Pharmaceutical compositions comprising an antibacterial agent nd antifungal agent and a nitroimidazole for the treatment and prevention of genitourinary infections and their extragenital complications |
US20050053648A1 (en) * | 2003-09-08 | 2005-03-10 | Chalmers Anne Marie | Medication delivery device |
EP1682063A1 (en) * | 2003-10-21 | 2006-07-26 | Ambo Innovation LLC | Digestible and volume adjustable multi medication delivery device |
US7803817B2 (en) * | 2005-05-11 | 2010-09-28 | Vecta, Ltd. | Composition and methods for inhibiting gastric acid secretion |
US7981908B2 (en) * | 2005-05-11 | 2011-07-19 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acid secretion |
CN100350900C (zh) * | 2005-05-23 | 2007-11-28 | 江西本草天工科技有限责任公司 | 复方降香双相胶囊及其制备方法 |
CN100350899C (zh) * | 2005-05-23 | 2007-11-28 | 江西本草天工科技有限责任公司 | 冠心丹参双相胶囊及其制备方法 |
CN100350898C (zh) * | 2005-05-23 | 2007-11-28 | 江西本草天工科技有限责任公司 | 复方三七双相胶囊及其制备方法 |
US8865197B2 (en) * | 2005-09-06 | 2014-10-21 | Israel Oceanographic And Limnological Research Ltd. | Food formulation for aquatic animals with integrated targeted delivery of bioactive agents |
JP2009511191A (ja) * | 2005-10-14 | 2009-03-19 | マイクロドース・テクノロジーズ・インコーポレーテッド | 経口投与剤組合せ型医薬パッケージ法 |
CN100393359C (zh) * | 2005-12-13 | 2008-06-11 | 济南百诺医药科技开发有限公司 | 根除幽门螺旋杆菌的多单元组合物 |
US8784886B2 (en) * | 2006-03-09 | 2014-07-22 | GlaxoSmithKline, LLC | Coating capsules with active pharmaceutical ingredients |
EP2081550B2 (en) | 2006-03-09 | 2021-05-26 | Reliant Pharmaceuticals, Inc. | Coating capsules with active pharmaceutical ingredients |
RU2467747C2 (ru) * | 2006-07-25 | 2012-11-27 | Векта Лтд. | Композиции и способы для ингибирования секреции желудочной кислоты с использованием производных малых дикарбоновых кислот в сочетании с ppi |
US20090087483A1 (en) * | 2007-09-27 | 2009-04-02 | Sison Raymundo A | Oral dosage combination pharmaceutical packaging |
US8439033B2 (en) | 2007-10-09 | 2013-05-14 | Microdose Therapeutx, Inc. | Inhalation device |
CN101513395B (zh) * | 2008-02-20 | 2011-01-12 | 单宝华 | 紫杉醇类双层软胶囊口服制剂药物 |
DE102009001334B4 (de) | 2009-03-04 | 2017-02-23 | Stefan Brosig | Einfache magensaftresistente Verkapselung, z.B. von Ingwer und anderen empfindlichen Stoffen |
CN101607086B (zh) * | 2009-07-21 | 2011-11-02 | 山西安特生物制药股份有限公司 | 一种复方铋剂组合物及其制备方法 |
TWI463998B (zh) * | 2009-12-31 | 2014-12-11 | Synmosa Biopharma Corp | Amoxicillin and clomycin have a high absorption rate of pharmaceutical ingredients |
CN105381524A (zh) | 2010-01-05 | 2016-03-09 | 微剂量治疗技术公司 | 吸入设备和方法 |
CN102349887A (zh) * | 2011-08-02 | 2012-02-15 | 天津市嵩锐医药科技有限公司 | 双氯芬酸钠对乙酰氨基酚胃肠型胶囊药物组合物 |
ITMI20120350A1 (it) * | 2012-03-06 | 2013-09-07 | Ultimate Italia S A S Di Levantino Enrico E C | Forma di dosaggio per somministrazione orale di principi attivi |
US20160008371A1 (en) * | 2014-07-14 | 2016-01-14 | Autotelic Llc | Fixed dose combination for pain relief without edema |
US9700514B1 (en) * | 2014-08-20 | 2017-07-11 | Darren Rubin | Single solid oral dosage forms for treating Helicobacter pylori infection and duodenal ulcer disease |
CN105106162A (zh) * | 2015-08-21 | 2015-12-02 | 四川百利药业有限责任公司 | 一种治疗幽门螺杆菌所引起溃疡的复方片剂及其制备方法 |
WO2017223043A1 (en) * | 2016-06-22 | 2017-12-28 | University Of Florida Research Foundation, Inc. | Pharmaceutical capsules for medication adherence monitoring and methods of forming the same |
CN108186968B (zh) * | 2018-01-08 | 2021-07-20 | 江苏聚荣制药集团有限公司 | 温胃舒胶囊 |
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GB825480A (en) | 1957-07-13 | 1959-12-16 | Johann Carl Pflueger | Improvements in or relating to ingestible dry micro-organism preparations and method for producing the same |
FR1454013A (fr) * | 1965-08-18 | 1966-07-22 | Pluripharm | Mode de présentation de deux médicaments associés |
DE2729068A1 (de) | 1977-06-28 | 1979-01-11 | Rainer Dr Med Liedtke | Verfahren zur freisetzungssteuerung von arzneimitteln aus kapseln |
CA1143287A (en) * | 1981-08-11 | 1983-03-22 | William C. Stewart | Waterproof edible encapsulation for prophylactic drugs |
DK150008C (da) | 1981-11-20 | 1987-05-25 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat |
US4642233A (en) | 1982-03-22 | 1987-02-10 | Alza Corporation | Gastrointestinal drug delivery system comprising a hydrogel reservoir containing a plurality of tiny pills |
FR2524311A1 (fr) * | 1982-04-05 | 1983-10-07 | Azalbert Gilles | Gelule compartimentee aux fins d'ingestions simultanees a effets differes |
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AU7966694A (en) | 1993-07-21 | 1996-05-02 | University Of Kentucky Research Foundation, The | A multicompartment hard capsule with control release properties |
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-
1997
- 1997-12-17 IT IT97MI002788A patent/IT1296980B1/it active IP Right Grant
-
1998
- 1998-12-11 MY MYPI98005603A patent/MY121713A/en unknown
- 1998-12-14 PL PL341737A patent/PL192541B1/pl unknown
- 1998-12-14 TR TR2000/01761T patent/TR200001761T2/xx unknown
- 1998-12-14 HU HU0100095A patent/HU225690B1/hu unknown
- 1998-12-14 CN CNB988130602A patent/CN1147292C/zh not_active Expired - Lifetime
- 1998-12-14 CZ CZ20002231A patent/CZ299181B6/cs not_active IP Right Cessation
- 1998-12-14 AT AT98966618T patent/ATE254910T1/de active
- 1998-12-14 WO PCT/EP1998/008167 patent/WO1999030693A2/en active IP Right Grant
- 1998-12-14 CA CA002315408A patent/CA2315408C/en not_active Expired - Lifetime
- 1998-12-14 DK DK98966618T patent/DK1037614T3/da active
- 1998-12-14 PT PT98966618T patent/PT1037614E/pt unknown
- 1998-12-14 AU AU24135/99A patent/AU743090B2/en not_active Expired
- 1998-12-14 EP EP98966618A patent/EP1037614B1/en not_active Expired - Lifetime
- 1998-12-14 ES ES98966618T patent/ES2212391T3/es not_active Expired - Lifetime
- 1998-12-14 NZ NZ505655A patent/NZ505655A/en not_active IP Right Cessation
- 1998-12-14 BR BR9812803-5A patent/BR9812803A/pt not_active Application Discontinuation
- 1998-12-14 KR KR10-2000-7006668A patent/KR100509351B1/ko active IP Right Grant
- 1998-12-14 US US09/581,721 patent/US6350468B1/en not_active Expired - Lifetime
- 1998-12-14 DE DE69820108T patent/DE69820108T2/de not_active Expired - Lifetime
- 1998-12-14 ID IDW20001355A patent/ID26340A/id unknown
- 1998-12-14 JP JP2000538676A patent/JP4615713B2/ja not_active Expired - Lifetime
- 1998-12-16 AR ARP980106414A patent/AR014126A1/es unknown
- 1998-12-16 PE PE1998001235A patent/PE20000512A1/es not_active IP Right Cessation
-
2000
- 2000-06-16 NO NO20003159A patent/NO329126B1/no not_active IP Right Cessation
-
2001
- 2001-07-27 HK HK01105239A patent/HK1034897A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC9A | Change of name, address |
Owner name: APTALIS PHARMA CANADA INC., CA Free format text: FORMER OWNER(S): AXCAN PHARMA INC., CA |