HUE065439T2 - Ionizálható kationos lipid RNS szállítására - Google Patents
Ionizálható kationos lipid RNS szállításáraInfo
- Publication number
- HUE065439T2 HUE065439T2 HUE17826404A HUE17826404A HUE065439T2 HU E065439 T2 HUE065439 T2 HU E065439T2 HU E17826404 A HUE17826404 A HU E17826404A HU E17826404 A HUE17826404 A HU E17826404A HU E065439 T2 HUE065439 T2 HU E065439T2
- Authority
- HU
- Hungary
- Prior art keywords
- cationic lipid
- rna delivery
- ionizable cationic
- ionizable
- rna
- Prior art date
Links
- -1 cationic lipid Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
- C07C333/04—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/387,067 US10383952B2 (en) | 2016-12-21 | 2016-12-21 | Ionizable cationic lipid for RNA delivery |
PCT/US2017/015886 WO2018118102A1 (en) | 2016-12-21 | 2017-01-31 | Ionizable cationic lipid for rna delivery |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE065439T2 true HUE065439T2 (hu) | 2024-05-28 |
Family
ID=58191571
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE17826404A HUE065439T2 (hu) | 2016-12-21 | 2017-12-20 | Ionizálható kationos lipid RNS szállítására |
Country Status (18)
Country | Link |
---|---|
US (3) | US10383952B2 (hu) |
EP (3) | EP3558942B1 (hu) |
JP (6) | JP6905062B2 (hu) |
KR (3) | KR20190134593A (hu) |
CN (3) | CN110337429B (hu) |
AU (3) | AU2017379587B2 (hu) |
CA (2) | CA3047033A1 (hu) |
DK (1) | DK3558943T3 (hu) |
ES (1) | ES2969232T3 (hu) |
FI (1) | FI3558943T3 (hu) |
HR (1) | HRP20231742T1 (hu) |
HU (1) | HUE065439T2 (hu) |
IL (4) | IL267317B2 (hu) |
PL (1) | PL3558943T3 (hu) |
PT (1) | PT3558943T (hu) |
RS (1) | RS65078B1 (hu) |
SI (1) | SI3558943T1 (hu) |
WO (1) | WO2018118102A1 (hu) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
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CA2930602C (en) | 2013-11-18 | 2019-05-28 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for rna delivery |
US10383952B2 (en) * | 2016-12-21 | 2019-08-20 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
US10526284B2 (en) | 2016-12-21 | 2020-01-07 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
US11433143B2 (en) * | 2017-05-18 | 2022-09-06 | The Regents Of The University Of California | Nano-enabled immunotherapy in cancer |
US11939600B2 (en) | 2017-05-31 | 2024-03-26 | Arcturus Therapeutics, Inc. | Compositions and methods for treating phenylketonuria |
AR112706A1 (es) | 2017-05-31 | 2019-12-04 | Ultragenyx Pharmaceutical Inc | Productos terapéuticos para la glucogenosis tipo iii |
CN113166783B (zh) | 2018-10-09 | 2024-10-11 | 不列颠哥伦比亚大学 | 包含无有机溶剂和去污剂的转染活性囊泡的组合物和系统以及与之相关的方法 |
EP4299750A3 (en) | 2018-12-06 | 2024-07-10 | Arcturus Therapeutics, Inc. | Compositions and methods for treating ornithine transcarbamylase deficiency |
TW202114732A (zh) | 2019-06-20 | 2021-04-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | 遞送b型肝炎病毒(hbv)疫苗之脂質奈米顆粒或脂質體 |
US20220347298A1 (en) | 2019-10-04 | 2022-11-03 | Ultragenyx Pharmaceutical Inc. | Methods for improved therapeutic use of recombinant aav |
KR102433471B1 (ko) * | 2019-10-17 | 2022-08-18 | 한국과학기술원 | 지질이 접합된 유전자편집 단백질 기반 crispr 복합체 및 이의 제조방법 |
US11744887B2 (en) * | 2020-03-09 | 2023-09-05 | Arcturus Therapeutics, Inc. | Coronavirus vaccine compositions and methods |
EP4178613A1 (en) | 2020-07-08 | 2023-05-17 | Janssen Sciences Ireland Unlimited Company | Rna replicon vaccines against hbv |
WO2022133230A1 (en) | 2020-12-18 | 2022-06-23 | Janssen Pharmaceuticals, Inc. | Combination therapy for treating hepatitis b virus infection |
AU2021412833A1 (en) | 2020-12-28 | 2023-07-06 | Arcturus Therapeutics, Inc. | Transcription activator-like effector nucleases (talens) targeting hbv |
TW202313557A (zh) * | 2021-05-06 | 2023-04-01 | 美商亞克圖羅斯醫療公司 | 用於rna遞送之可離子化陽離子脂質 |
CN113633766B (zh) * | 2021-08-11 | 2023-06-30 | 通用生物(安徽)股份有限公司 | 一种脂质体核酸疫苗佐剂及其制备方法 |
IL309505A (en) | 2021-09-03 | 2024-02-01 | CureVac SE | Lipid nanoparticles for nucleic acid delivery |
AR127312A1 (es) | 2021-10-08 | 2024-01-10 | Suzhou Abogen Biosciences Co Ltd | Compuestos lipídicos ycomposiciones de nanopartículas lipídicas |
WO2023073228A1 (en) | 2021-10-29 | 2023-05-04 | CureVac SE | Improved circular rna for expressing therapeutic proteins |
IL313876A (en) * | 2021-12-27 | 2024-08-01 | Univ Texas | Compositions and methods for targeted delivery to cells |
WO2023144330A1 (en) | 2022-01-28 | 2023-08-03 | CureVac SE | Nucleic acid encoded transcription factor inhibitors |
CN116354836A (zh) * | 2022-03-25 | 2023-06-30 | 深圳市新合生物医疗科技有限公司 | 阳离子脂质化合物及其制备方法和应用、以及mRNA递送系统 |
WO2023218420A1 (en) | 2022-05-13 | 2023-11-16 | Janssen Pharmaceuticals, Inc. | Mrna compositions for inducing latent hiv-1 reversal |
WO2023227608A1 (en) | 2022-05-25 | 2023-11-30 | Glaxosmithkline Biologicals Sa | Nucleic acid based vaccine encoding an escherichia coli fimh antigenic polypeptide |
WO2023233290A1 (en) | 2022-05-31 | 2023-12-07 | Janssen Sciences Ireland Unlimited Company | Rnai agents targeting pd-l1 |
WO2024040195A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
WO2024089638A1 (en) | 2022-10-28 | 2024-05-02 | Glaxosmithkline Biologicals Sa | Nucleic acid based vaccine |
WO2024141784A2 (en) | 2022-12-29 | 2024-07-04 | Popvax Private Limited | Broadly protective betacoronavirus vaccines and compositions |
WO2024141786A2 (en) | 2022-12-29 | 2024-07-04 | Popvax Private Limited | Multitarget vaccines and therapeutics |
CN115745820B (zh) * | 2023-01-05 | 2023-04-28 | 北京悦康科创医药科技股份有限公司 | 长效低毒的新型阳离子脂质化合物及其组合物 |
CN116396178A (zh) * | 2023-01-05 | 2023-07-07 | 北京悦康科创医药科技股份有限公司 | 用于递送核酸的可电离阳离子脂质化合物和组合物及用途 |
WO2024184500A1 (en) | 2023-03-08 | 2024-09-12 | CureVac SE | Novel lipid nanoparticle formulations for delivery of nucleic acids |
Family Cites Families (27)
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FR1481016A (fr) | 1962-04-02 | 1967-05-19 | Bruneau & Cie Lab | Dérivés de la pipérazine et leur fabrication |
EP0079963B1 (en) | 1981-06-04 | 1986-08-27 | Delaware Chemicals Corporation | Pressurized container with dispensing pump |
JPS6189286A (ja) | 1984-10-08 | 1986-05-07 | Tokuyama Soda Co Ltd | 液晶組成物 |
JPS61136584A (ja) | 1984-12-07 | 1986-06-24 | Tokuyama Soda Co Ltd | 液晶組成物 |
US4778810A (en) | 1987-01-08 | 1988-10-18 | Nastech Pharmaceutical Co., Inc. | Nasal delivery of caffeine |
DE69123979T2 (de) | 1990-10-12 | 1997-04-30 | Max Planck Gesellschaft | Abgeänderte ribozyme |
US5652094A (en) | 1992-01-31 | 1997-07-29 | University Of Montreal | Nucleozymes |
US5849902A (en) | 1996-09-26 | 1998-12-15 | Oligos Etc. Inc. | Three component chimeric antisense oligonucleotides |
FR2858216B1 (fr) | 2003-07-31 | 2008-04-04 | Oreal | Composition contenant un 2-thioacetamide, son utilisation pour stimuler la pousse des fibres keratiniques et/ou freiner leur chute |
CN102215820A (zh) * | 2008-11-17 | 2011-10-12 | 安龙制药公司 | 用于核酸输送系统的可释放融合脂质 |
KR101727333B1 (ko) | 2008-11-26 | 2017-04-14 | 추가이 세이야쿠 가부시키가이샤 | 베시클 제제 |
EA028860B1 (ru) | 2009-06-10 | 2018-01-31 | Арбутус Биофарма Корпорэйшн | Улучшенная липидная композиция |
AU2011245987B2 (en) | 2010-04-28 | 2016-12-15 | Kyowa Hakko Kirin Co., Ltd | Cationic lipid |
WO2011136369A1 (ja) | 2010-04-28 | 2011-11-03 | 協和発酵キリン株式会社 | カチオン性脂質 |
AU2011261247B2 (en) | 2010-06-03 | 2016-08-25 | Alnylam Pharmaceuticals, Inc. | Biodegradable lipids for the delivery of active agents |
EP2629802B1 (en) | 2010-10-21 | 2019-12-04 | Sirna Therapeutics, Inc. | Low molecular weight cationic lipids for oligonucleotide delivery |
US9011903B2 (en) | 2011-06-08 | 2015-04-21 | Nitto Denko Corporation | Cationic lipids for therapeutic agent delivery formulations |
RU2769872C2 (ru) | 2011-06-08 | 2022-04-07 | Нитто Денко Корпорейшн | СОЕДИНЕНИЯ ДЛЯ НАЦЕЛЕННОЙ ДОСТАВКИ ЛЕКАРСТВЕННОГО СРЕДСТВА И УСИЛЕНИЯ АКТИВНОСТИ siPHK |
JP2013095755A (ja) * | 2011-11-02 | 2013-05-20 | Kyowa Hakko Kirin Co Ltd | カチオン性脂質 |
US9579338B2 (en) | 2011-11-04 | 2017-02-28 | Nitto Denko Corporation | Method of producing lipid nanoparticles for drug delivery |
US20140308304A1 (en) | 2011-12-07 | 2014-10-16 | Alnylam Pharmaceuticals, Inc. | Lipids for the delivery of active agents |
RU2658007C2 (ru) * | 2012-06-08 | 2018-06-19 | Нитто Денко Корпорейшн | Липиды для композиций для доставки терапевтических агентов |
US9365610B2 (en) | 2013-11-18 | 2016-06-14 | Arcturus Therapeutics, Inc. | Asymmetric ionizable cationic lipid for RNA delivery |
CA2930602C (en) | 2013-11-18 | 2019-05-28 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for rna delivery |
JP6637988B2 (ja) | 2014-11-18 | 2020-01-29 | アークトゥルス セラピューティクス, インコーポレイテッド | Rna送達のためのイオン化可能カチオン性脂質 |
US10383952B2 (en) * | 2016-12-21 | 2019-08-20 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
US10526284B2 (en) | 2016-12-21 | 2020-01-07 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
-
2016
- 2016-12-21 US US15/387,067 patent/US10383952B2/en active Active
-
2017
- 2017-01-31 EP EP17708003.3A patent/EP3558942B1/en active Active
- 2017-01-31 JP JP2019533351A patent/JP6905062B2/ja active Active
- 2017-01-31 KR KR1020197021153A patent/KR20190134593A/ko not_active Application Discontinuation
- 2017-01-31 CN CN201780087021.3A patent/CN110337429B/zh active Active
- 2017-01-31 IL IL267317A patent/IL267317B2/en unknown
- 2017-01-31 CA CA3047033A patent/CA3047033A1/en not_active Abandoned
- 2017-01-31 AU AU2017379587A patent/AU2017379587B2/en active Active
- 2017-01-31 WO PCT/US2017/015886 patent/WO2018118102A1/en unknown
- 2017-12-20 HR HRP20231742TT patent/HRP20231742T1/hr unknown
- 2017-12-20 EP EP23196560.9A patent/EP4310075A3/en active Pending
- 2017-12-20 EP EP17826404.0A patent/EP3558943B1/en active Active
- 2017-12-20 SI SI201731472T patent/SI3558943T1/sl unknown
- 2017-12-20 AU AU2017379059A patent/AU2017379059B2/en active Active
- 2017-12-20 DK DK17826404.0T patent/DK3558943T3/da active
- 2017-12-20 CA CA3046885A patent/CA3046885C/en active Active
- 2017-12-20 PT PT178264040T patent/PT3558943T/pt unknown
- 2017-12-20 IL IL306099A patent/IL306099A/en unknown
- 2017-12-20 FI FIEP17826404.0T patent/FI3558943T3/fi active
- 2017-12-20 IL IL290592A patent/IL290592B2/en unknown
- 2017-12-20 ES ES17826404T patent/ES2969232T3/es active Active
- 2017-12-20 CN CN201780086949.XA patent/CN110325511B/zh active Active
- 2017-12-20 JP JP2019533410A patent/JP7437935B2/ja active Active
- 2017-12-20 KR KR1020197021199A patent/KR102299053B1/ko active IP Right Grant
- 2017-12-20 PL PL17826404.0T patent/PL3558943T3/pl unknown
- 2017-12-20 KR KR1020217027797A patent/KR102385562B1/ko active IP Right Grant
- 2017-12-20 RS RS20240048A patent/RS65078B1/sr unknown
- 2017-12-20 CN CN202210319695.4A patent/CN114917203A/zh active Pending
- 2017-12-20 HU HUE17826404A patent/HUE065439T2/hu unknown
-
2019
- 2019-06-19 IL IL267511A patent/IL267511B/en unknown
- 2019-07-31 US US16/527,955 patent/US10980895B2/en active Active
-
2021
- 2021-01-29 JP JP2021013021A patent/JP2021073263A/ja not_active Withdrawn
- 2021-02-02 AU AU2021200663A patent/AU2021200663B2/en active Active
- 2021-02-22 JP JP2021026300A patent/JP2021088588A/ja not_active Withdrawn
- 2021-04-19 US US17/234,571 patent/US20210252163A1/en active Pending
-
2023
- 2023-03-08 JP JP2023035778A patent/JP2023071947A/ja active Pending
- 2023-03-08 JP JP2023035835A patent/JP2023071950A/ja active Pending
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