HUE049352T2 - Anyagok és módszerek egy vízoldható zsírsavszármazéknak egy fehérjéhez való konjugálására - Google Patents

Anyagok és módszerek egy vízoldható zsírsavszármazéknak egy fehérjéhez való konjugálására

Info

Publication number
HUE049352T2
HUE049352T2 HUE11806103A HUE11806103A HUE049352T2 HU E049352 T2 HUE049352 T2 HU E049352T2 HU E11806103 A HUE11806103 A HU E11806103A HU E11806103 A HUE11806103 A HU E11806103A HU E049352 T2 HUE049352 T2 HU E049352T2
Authority
HU
Hungary
Prior art keywords
conjugating
protein
materials
methods
fatty acid
Prior art date
Application number
HUE11806103A
Other languages
English (en)
Inventor
Juergen Siekmann
Richard Scheinecker
Hanspeter Rottensteiner
Peter Turecek
Original Assignee
Baxalta GmbH
Baxalta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta GmbH, Baxalta Inc filed Critical Baxalta GmbH
Publication of HUE049352T2 publication Critical patent/HUE049352T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
HUE11806103A 2010-12-22 2011-12-16 Anyagok és módszerek egy vízoldható zsírsavszármazéknak egy fehérjéhez való konjugálására HUE049352T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201061426356P 2010-12-22 2010-12-22

Publications (1)

Publication Number Publication Date
HUE049352T2 true HUE049352T2 (hu) 2020-09-28

Family

ID=45464916

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE11806103A HUE049352T2 (hu) 2010-12-22 2011-12-16 Anyagok és módszerek egy vízoldható zsírsavszármazéknak egy fehérjéhez való konjugálására

Country Status (20)

Country Link
US (1) US8945897B2 (hu)
EP (2) EP3673921A1 (hu)
JP (1) JP6138052B2 (hu)
KR (1) KR102025442B1 (hu)
CN (1) CN103269723B (hu)
AR (1) AR084576A1 (hu)
AU (2) AU2011349574B9 (hu)
BR (1) BR112013015898A2 (hu)
CA (1) CA2822591C (hu)
DK (1) DK2654794T3 (hu)
EA (1) EA032056B1 (hu)
ES (1) ES2800983T3 (hu)
HU (1) HUE049352T2 (hu)
MX (1) MX345608B (hu)
NZ (1) NZ612320A (hu)
PL (1) PL2654794T3 (hu)
PT (1) PT2654794T (hu)
SG (1) SG191298A1 (hu)
TW (1) TWI546279B (hu)
WO (1) WO2012087838A1 (hu)

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