HUE046982T2 - 3' UTR szekvenciák az RNA stabilizálására - Google Patents

3' UTR szekvenciák az RNA stabilizálására

Info

Publication number
HUE046982T2
HUE046982T2 HUE16778784A HUE16778784A HUE046982T2 HU E046982 T2 HUE046982 T2 HU E046982T2 HU E16778784 A HUE16778784 A HU E16778784A HU E16778784 A HUE16778784 A HU E16778784A HU E046982 T2 HUE046982 T2 HU E046982T2
Authority
HU
Hungary
Prior art keywords
rna
stabilization
utr sequences
utr
sequences
Prior art date
Application number
HUE16778784A
Other languages
English (en)
Inventor
Von Niessen Alexandra Orlandini
Stephanie Fesser
Britta Vallazza
Tim Beissert
Andreas Kuhn
Ugur Sahin
Marco Alexander Poleganov
Original Assignee
Biontech Rna Pharmaceuticals Gmbh
Tron Translationale Onkologie An Der Univ Der Johannes Gutenberg Univ Mainz Gemeinnuetzige Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biontech Rna Pharmaceuticals Gmbh, Tron Translationale Onkologie An Der Univ Der Johannes Gutenberg Univ Mainz Gemeinnuetzige Gmbh filed Critical Biontech Rna Pharmaceuticals Gmbh
Publication of HUE046982T2 publication Critical patent/HUE046982T2/hu

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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
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    • A47B2200/0018—Nodal leg assembly for table in two parts
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  • Organic Chemistry (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
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  • Biophysics (AREA)
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  • Communicable Diseases (AREA)
  • Developmental Biology & Embryology (AREA)
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HUE16778784A 2015-10-07 2016-10-05 3' UTR szekvenciák az RNA stabilizálására HUE046982T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2015/073180 WO2017059902A1 (en) 2015-10-07 2015-10-07 3' utr sequences for stabilization of rna

Publications (1)

Publication Number Publication Date
HUE046982T2 true HUE046982T2 (hu) 2020-04-28

Family

ID=54293227

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE19198322A HUE055152T2 (hu) 2015-10-07 2016-10-05 3'UTR szekvenciák az RNA stabilizálására
HUE16778784A HUE046982T2 (hu) 2015-10-07 2016-10-05 3' UTR szekvenciák az RNA stabilizálására

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE19198322A HUE055152T2 (hu) 2015-10-07 2016-10-05 3'UTR szekvenciák az RNA stabilizálására

Country Status (26)

Country Link
US (2) US11492628B2 (hu)
EP (3) EP3636764B1 (hu)
JP (5) JP7084302B2 (hu)
KR (2) KR20220025195A (hu)
CN (1) CN108291230B (hu)
AU (3) AU2016335029B2 (hu)
BR (2) BR122021025194B1 (hu)
CA (2) CA2998554C (hu)
CY (2) CY1122347T1 (hu)
DK (2) DK3337902T3 (hu)
ES (2) ES2753201T3 (hu)
HK (2) HK1256701A1 (hu)
HR (2) HRP20191907T1 (hu)
HU (2) HUE055152T2 (hu)
IL (3) IL293020A (hu)
LT (2) LT3636764T (hu)
MX (2) MX2018004160A (hu)
NZ (1) NZ740946A (hu)
PL (2) PL3337902T3 (hu)
PT (2) PT3636764T (hu)
RS (2) RS61684B1 (hu)
RU (1) RU2720934C2 (hu)
SG (1) SG10201912558YA (hu)
SI (2) SI3636764T1 (hu)
WO (2) WO2017059902A1 (hu)
ZA (1) ZA201800835B (hu)

Families Citing this family (98)

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WO2017059902A1 (en) * 2015-10-07 2017-04-13 Biontech Rna Pharmaceuticals Gmbh 3' utr sequences for stabilization of rna
EP3481430A4 (en) 2016-07-11 2020-04-01 Translate Bio Ma, Inc. NUCLEIC ACID CONJUGATES AND USES THEREOF
CA3072960A1 (en) * 2017-08-15 2019-02-21 Intellia Therapeutics, Inc. Stabilized nucleic acids encoding messenger ribonucleic acid (mrna)
CN111741764A (zh) 2018-02-12 2020-10-02 生物技术Rna制药有限公司 使用细胞因子编码rna的治疗
CN112771072A (zh) 2018-07-24 2021-05-07 生物技术Rna制药有限公司 Il2激动剂
TW202043272A (zh) 2019-01-14 2020-12-01 美商建南德克公司 使用pd-1軸結合拮抗劑及rna疫苗治療癌症之方法
KR20210124236A (ko) 2019-02-08 2021-10-14 비온테크 쎌 & 제네 테라피스 게엠베하 Car-조작된 t 세포 및 사이토카인을 수반한 치료
CA3133414A1 (en) 2019-03-18 2020-09-24 Biontech Cell & Gene Therapies Gmbh Interleukin-2 receptor (il2r) and interleukin-2 (il2) variants for specific activation of immune effector cells
WO2020200481A1 (en) 2019-04-05 2020-10-08 Biontech Rna Pharmaceuticals Gmbh Treatment involving interleukin-2 (il2) and interferon (ifn)
TW202115105A (zh) 2019-06-24 2021-04-16 德商拜恩迪克Ｒｎａ製藥有限公司 Ｉｌ２激動劑
EP4022068A1 (en) * 2019-08-29 2022-07-06 Universität Zürich Minimal messenger rnas and uses thereof
WO2021081261A1 (en) * 2019-10-22 2021-04-29 The Regents Of The University Of California Modulation of engineered immune cell receptor translation using noncoding sequence elements
MX2022009391A (es) 2020-01-31 2022-09-26 Genentech Inc Metodos para inducir linfocitos t especificos para neoepitopo con un antagonista de union al eje de pd-1 y una vacuna de arn.
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