HUE033611T2 - Gyógyszerészeti készítmények és a kapcsolódó adagolási eljárások - Google Patents

Gyógyszerészeti készítmények és a kapcsolódó adagolási eljárások Download PDF

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Publication number
HUE033611T2
HUE033611T2 HUE09814164A HUE09814164A HUE033611T2 HU E033611 T2 HUE033611 T2 HU E033611T2 HU E09814164 A HUE09814164 A HU E09814164A HU E09814164 A HUE09814164 A HU E09814164A HU E033611 T2 HUE033611 T2 HU E033611T2
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Hungary
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formulation
ahol ahol
formulations
administration
composition
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HUE09814164A
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English (en)
Inventor
Paul Salama
Roni Mamluk
Karen Marom
Irina Weinstein
Moshe Tzabari
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Chiasma Inc
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41277888&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE033611(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiasma Inc filed Critical Chiasma Inc
Publication of HUE033611T2 publication Critical patent/HUE033611T2/hu

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Claims (4)

  1. Saabadalto; igetsyptmlok
  2. 5. Setssapeoalsk farté kA&Só kesasomm: antely sausapestaió .iartalfóaaaa nisStOfob liöeag és sasiábd sorosa kervsekás. aboi a sábárd forrná noe-kssaasa icog-iás - -1:5 terápiásad hatásos oa-susyoegA -A kóáepes Istaéú ysPsav legalább egy sój-H. és ahol a köáópás kbseá asltsa v súg; « késaltátestybe!· 10 Sösoagvá vágy eáoel svsgyobb so eo hy kságbá ss van je less, ahol a setApsas :;:··χ·γ ok tivoliik 2. A:·· 1 igéisypom saeriotyksaaidyeay, ahol asaslard lossaa íariylnsaa résaecskei éAvagy port. 3. A? g. vagy a, i-esp-p-vsS ssa.v.riso: A:;; /ösvény. ahoi a gyógyxaerésaetl kessaäoK-sphers a vAinnakno kb. 6 tomegká-isál kisebb vagy kb, 2 íösnag>é-sms kisebb, 'vagy ahoi :.s sailásd ibnoslbsso a vAnsossksso kh 6 sosoeoA.-sv-i k Aol-b vágj ide 2 ;ö!oeg%-rsál kisebb. -i. A? 1-4. iggssypoosok i;ab::oesy|ke yaeslnsi késáltorásty, aboi a kbaapas iaaeô /Ársáv sOiá kb. 6-1-4 sábnaussssey lástchossaíkAggid svssdAkaaá·:. vápából a köaepes láncú asirsav »ója a nalriam-hevaoosy oáhits-rr-hepissooáb nátna-o-oksaanái. 'nátrium-nnasnoat nátti'um-dekanoák ssáíriiun-uodekénoál, Mirium-dodekaswsi ssáítioto-indekasutás vagy nán-Hots--íeífsssdeksmoáp vagya sroigfekbö ksikn«-- vagy bútoré· vagy amosdnhánsó vagy caak komhmáelsljá.
    5. Aa I -4, sgostypstmok bármelyike saarinb kesaan:éííy, aboi a kőáepes; lassest ásslrsstv apja a kisdiméoybea I 490 !Ömeg% vagy 1244 kian.grA otéstssyiségbes; vau jálésy vágy ahol a kösepes tásseá ®»i?sav soiá ä sailárd f<s rutában 50-90 tosncsyA vagy 20-40 :öhseg% Snennyiségbess Via: jeleik ó. Aa i-5, sgáhyptssuok bársneiyike saerlnp kbsastisAsiy.. asltsdy balabpaá továbbá spápaas)! kialakító pulimért, stniely a kásái tsnásty bee 5 Ulssvsg'A vagy emséi Stagyobb bssPtaySsbgbeis vast jeieOi ?. A 0, igánypom sAájnb késaiohépy, áltól á mátrixot kialákitó polimer a sieafrsiit, poiiymsIpisTöisstoss, i'PVP), iostoa vagy sstpleges poibssmssharsd-A. pakaksilsav. ppIk-ípetaki'ilsáv-sááláTSíraókPk vagy pobysílibalkobols 4. A 1, igenypoöt szesinb kesáihrséoy. aboi a poliviniipirroláfon a kásálOTíányben kb. 2~2ö sotneg%. 54S tbmeg% vagy kb, 10 sörssegA, ntimtsyAégbeti vats jelen, 9. A / vagy 4. Iggeypoas szerinti kbsaione-p, alsói a pokvinlipirroilsior; a PVP-12 és/vagy a pollvií-iiplí'robdoií irioiektikrOotuge kb. -000.
  3. 16. Aa 49. i'génypo«tok banesbyike saerisOi kés.aioTsény, sthol g bidtofób kOáag iytaabsnsá rtomusóléjst vagy giieeni-lrlkapnlams vagy giieerllAdbmbáíoi vagy eaek kombinációját. 1 ;. A a i-iö. sgáítypoótok bámielyiks r.ávthni kéyálopéáy, óból á bibrxsíób köaeg töomg saerinfi ISkoípponeáse ybs;esíl-!íiksipíilás, vagy ahol s hidroíbb koasg álápvatóéh gHeerls-trlkaprlsatbssi áll.
    12. Αχ ΙΊ1. igánypssiitsík bórovdvlke saetipti kèsaiotiény. ssbol a hidtítfób köaeg laiValsrsa* aiiibs. olebn. éiklusos vagy aromás yegyöletes, vagy aboi s. hídrofób kóaeg tortai-max ásvasiyi olaja·, p.soOÍ'ink asíltsovas, mini :példáál ssktásmíivss·, •«öíKsgiieenoci, dlglíeetseeo irigbeerides, átess vagy ess 1st; vagy exek kostsl>its;k.ió;ái. előnyös«.'» ahol » nidtoföb közeg tartalmaz trigiiectidet amely hosszá: iónén logíiecnsL közepes lánc» g! d W á'tv S'- ' ·'* '('v\^<vv V isié ig Μ’Ά igestygenipk bármelyike smrinb készítmény. ahol a hkiroöüb leiöiíkakiéyagyagát vagy sum:-ionos îcHsieUâki· v anyagot. !y4:,,¾ ill, igénypont v zen mi készamém. ahol a íolütetaköv anyag a k-mím vagy epeso ν'*ϋ·> üeíergcsts. sage ahoi » ieiölesakds an>ag égy monogkeerid, eremopliof, poiiehiéB-gbkobzsiraíkoi'mi^t'· sKOí'biiiáS· zskbayksáfák |Cs.i>^:Sï?iίίΐriKVíi.>:§i^0?íí?:NáiíÍl'^ifí’liEíii.iiíéSíííéry. ié-isMtvsiszieaHnsav pohosáét! lén ész.-era, vagy pok»m.mer vagy 1 ôj îî , előnyösen • aboi a monogtkerni giBerinösonokaprilsk igiinorilrnisnookkänöPk gbcerrMTarnodek^nosi, glscsríl· tapPölanröt. giscofii-niooooiir-s/nif. gitcerikmwöpalronái vagy gii een krnonoö Icát vagy sdiestbemonoszteank Vagy ezek kombinációja, vagy • ahol « szorbiíáB-z:sitva'.msz.ier taríakvtsz szorbttáts-monolaormoí, szöíbííánYmonoöieáiöí: vagy ntonopsbeitátot vagy ezek kombináció««!, vagy > ahol ;; poíioxletóén-szorbúámzalrsavészter íanshnaz polnmkblén-szorbhán-monoolcáíok podt-moakiém .szorbitáír-mmRezimaátot vagy poMöNiettíén-szorbisáB-nionopalmitáK» vagy ezek kombinációját
    15. Λ ii'ik.: igénypont szerinti készítmény: ahol a hidtolöb közeg tanaitnaz továbbá ncinusoiajat és/vagy gbegyiiibonökniki iósbk 16. kijárás az. Mg. igénypontok bittnclyihe szerinti gyógyszefészeti ivás/ámány előállítására. amely eljápiá tapaimázza oktreotip terápiása» hatás«;; mennyisége szilárd iförmöjlnák ás közepes láncé zsírsav sói; taríaitnazó szilárd lopna biztosítása;. es a smmrd tormák Seisznrzpeudálávát hkirolob közegben, és így SzusgpepKiőt: áilfíuiife elő, amely tartalmazza szilárd tormában az okireotidet ás a közepes láncú zsírsav sót. és száká! giyögyszercszeti Iseszilrnoiryä álbtnnk élö. aboi a gyögyszerépöii MSzlúTtéíty JíHömegSá vágy ennél több közepes iánaá zsksav soi taslalmaz. 17. : Az. i-;?. igénypontok bármelyike szerinti készkmérp ; antÇly iäpaimagza &amp; következőket 1 0-2<}%. előnyösen :0-1:1%. előnyősért ΙίΊδ közepes láncú zsirs&amp;v sö, előnyösáh nánmm-olaanoat. S~i0%. előnyőseit !ú% kVl--i2. éy ahol a bidrefőö közeg:iiiartslmáz 20-80%, előnyösen 10-70¾ íriglmerkSet. előnyösen giicedl· ír ikajtrt látót vagy giiceril'-iribntirhtei vagy tidnpaplaiiai vagy ezek keverékét, Időéi télötdáMv anyagok előnyösemööá glieeril'-monokapniátoi éir:ροIízt1-¾1:¾ tÖZOk és ahol az::.ö:klreoiió; aflf-nsi kisebb vagy 2á%-»si kisebb vagy ifi őo-ná! kisebb vagy Ifá-Oál kó.nbb vagy (r l%--nái kisebb mennyise gbesv van jel en. 11, az isi 5. vagy íX, fgéfiypontois: bármelyike szeriről készítményt, amely adott e-ictben lehel kapsznla és lehel kömény oéikapxznia vagy lágy gélkaps/uia. es amely adott esetben lehet belh-m oldód« be vonallal ellátott 1» Készítmény az. 1-is. vagy 17. igény pontok hát melyike szerint akromegáiia kezeléseket; történő alkalmazásra.
  4. 20. Készítmény alkaünazássa a 1 0. igénypont szerint, aboi a készítmény egy orális öözmlörma.
HUE09814164A 2008-09-17 2009-09-17 Gyógyszerészeti készítmények és a kapcsolódó adagolási eljárások HUE033611T2 (hu)

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