DE69807281T2 - Difluprednat enthaltende Zusammensetzungen - Google Patents

Difluprednat enthaltende Zusammensetzungen

Info

Publication number
DE69807281T2
DE69807281T2 DE69807281T DE69807281T DE69807281T2 DE 69807281 T2 DE69807281 T2 DE 69807281T2 DE 69807281 T DE69807281 T DE 69807281T DE 69807281 T DE69807281 T DE 69807281T DE 69807281 T2 DE69807281 T2 DE 69807281T2
Authority
DE
Germany
Prior art keywords
compositions containing
containing difluprednate
difluprednate
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69807281T
Other languages
English (en)
Other versions
DE69807281D1 (de
Inventor
Masako Kimura
Shin-Ichi Yasueda
Masazumi Yamaguchi
Katsuhiro Inada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Mitsubishi Chemical Corp
Original Assignee
Senju Pharmaceutical Co Ltd
Mitsubishi Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14884920&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69807281(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Senju Pharmaceutical Co Ltd, Mitsubishi Chemical Corp filed Critical Senju Pharmaceutical Co Ltd
Publication of DE69807281D1 publication Critical patent/DE69807281D1/de
Application granted granted Critical
Publication of DE69807281T2 publication Critical patent/DE69807281T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
DE69807281T 1997-05-14 1998-05-12 Difluprednat enthaltende Zusammensetzungen Expired - Lifetime DE69807281T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12441597 1997-05-14

Publications (2)

Publication Number Publication Date
DE69807281D1 DE69807281D1 (de) 2002-09-26
DE69807281T2 true DE69807281T2 (de) 2003-04-17

Family

ID=14884920

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69807281T Expired - Lifetime DE69807281T2 (de) 1997-05-14 1998-05-12 Difluprednat enthaltende Zusammensetzungen

Country Status (6)

Country Link
US (1) US6114319A (de)
EP (1) EP0878197B1 (de)
KR (1) KR19980087017A (de)
CN (1) CN1200926A (de)
CA (1) CA2237503A1 (de)
DE (1) DE69807281T2 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1613346T3 (da) 2003-04-04 2013-01-07 Pah Usa 15 Llc Mikrofluidiske olie-i-vand-emulsioner og vaccinesammensætninger
AU2005329255B2 (en) 2004-04-15 2010-09-30 Chiasma, Inc. Compositions capable of facilitating penetration across a biological barrier
AU2005304034B2 (en) 2004-11-09 2012-02-16 Santen Sas Ophthalmic emulsions containing an immunosuppressive agent
ES2314354T3 (es) 2004-11-09 2009-03-16 Novagali Pharma S.A. Emulsion de tipo aceite en agua con baja concentracion de agente cationico y potencial zeta positivo.
CN101137359B (zh) 2005-03-10 2011-01-12 3M创新有限公司 治疗耳感染的方法
US20070280902A1 (en) 2006-06-01 2007-12-06 Laura Rabinovich-Guilatt Method for treating eye disease or conditions affecting the posterior segment of the eye
WO2008035246A2 (en) 2006-07-28 2008-03-27 Novagali Pharma Sa Compositions containing quaternary ammonium compounds
US20090263345A1 (en) * 2008-01-28 2009-10-22 Foresight Biotherapeutics, Inc. Otic compositions for the treatment of infections of the internal and external ear in mammals
MX2011002836A (es) 2008-09-17 2011-04-28 Chiasma Inc Composiciones farmaceúticas y métodos de administración relacionados.
TW201105363A (en) 2009-07-14 2011-02-16 Univ Yamagata Eye drop for macular edema treatment
BR112013019257B1 (pt) 2011-01-26 2019-09-03 Allergan Inc composição de androgênio para tratar uma condição oftálmica
WO2013098841A1 (en) 2011-10-31 2013-07-04 Fdc Limited Nanodispersion of poorly water soluble drug(s)
CN103130859B (zh) * 2011-11-30 2015-12-02 天津金耀集团有限公司 二氟泼尼酯晶型i及其制备方法
CN103130857A (zh) * 2011-11-30 2013-06-05 天津金耀集团有限公司 二氟泼尼酯ⅱ晶型及其制备方法
CN103126983B (zh) * 2011-11-30 2016-02-03 天津金耀集团有限公司 二氟泼尼酯晶型i制备的乳剂
US9278132B2 (en) * 2012-02-13 2016-03-08 Bausch & Lomb Incorporated Ophthalmic pharmaceutical compositions and methods of making and using same
WO2013179253A1 (en) * 2012-06-02 2013-12-05 Micro Labs Limited Dose combination comprising nsaid and steroidal anti-inflammatory agent for treating post operative ocular inflammation
CN103919718B (zh) * 2013-01-11 2016-12-28 沈阳兴齐眼药股份有限公司 一种维生素a棕榈酸酯滴眼剂及其制备方法和用途
JP6226998B2 (ja) * 2013-02-15 2017-11-08 千寿製薬株式会社 抗菌性金属を含有するジフルプレドナートエマルション組成物
KR20150119315A (ko) * 2013-02-15 2015-10-23 센주 세이야꾸 가부시키가이샤 아연을 함유하는 디플루프레드네이트 유액 조성물
CN103364502B (zh) * 2013-07-04 2015-04-22 山东省医药工业研究所 一种二氟泼尼酯中有关物质的hplc测定方法
MA41462A (fr) 2015-02-03 2021-05-12 Chiasma Inc Méthode de traitement de maladies
WO2016127022A1 (en) 2015-02-06 2016-08-11 Foreman James Michael Preparation of an oil-in-water emulsion for polymer stabilized pharmaceutical formulations
WO2017064731A1 (en) 2015-10-16 2017-04-20 Sun Pharma Advanced Research Company Limited Ophthalmic solution of difluprednate
JP7044714B2 (ja) 2016-11-17 2022-03-30 千寿製薬株式会社 乳剤点眼液
US20240000802A1 (en) 2020-12-03 2024-01-04 Sun Pharma Advanced Research Company Limited Difluprednate for reducing the adverse effects of ocular inflammation
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3780177A (en) * 1967-06-16 1973-12-18 Warner Lambert Co 17-butyrate,21-ester derivatives of 6alpha,9alpha-difluoroprednisolone,compositions and use
JPS56135416A (en) * 1980-03-27 1981-10-22 Mitsubishi Chem Ind Ltd Pharmaceutical preparation for skin
JPH0543465A (ja) * 1991-08-08 1993-02-23 Mitsubishi Kasei Corp コルチコステロイド含有ローシヨン剤
AU684115B2 (en) * 1993-12-27 1997-12-04 Mitsubishi Chemical Corporation Ophthalmic suspension containing diflupredonate
WO1998030221A1 (fr) * 1997-01-10 1998-07-16 Wakamoto Pharmaceutical Co., Ltd. Composition de type emulsion huile/eau a usage ophtalmique et contenant du difluprednate

Also Published As

Publication number Publication date
DE69807281D1 (de) 2002-09-26
EP0878197A1 (de) 1998-11-18
US6114319A (en) 2000-09-05
EP0878197B1 (de) 2002-08-21
KR19980087017A (ko) 1998-12-05
CN1200926A (zh) 1998-12-09
CA2237503A1 (en) 1998-11-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition