IT1263840B - Formulazioni orali di ubidecarenone in forma di capsule - Google Patents

Formulazioni orali di ubidecarenone in forma di capsule

Info

Publication number
IT1263840B
IT1263840B ITMI930605A ITMI930605A IT1263840B IT 1263840 B IT1263840 B IT 1263840B IT MI930605 A ITMI930605 A IT MI930605A IT MI930605 A ITMI930605 A IT MI930605A IT 1263840 B IT1263840 B IT 1263840B
Authority
IT
Italy
Prior art keywords
capsules
ubidecarenone
oral formulations
active ingredient
isopropyl
Prior art date
Application number
ITMI930605A
Other languages
English (en)
Inventor
Giuseppe Furiosi
Original Assignee
Giuseppe Furiosi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giuseppe Furiosi filed Critical Giuseppe Furiosi
Priority to ITMI930605A priority Critical patent/IT1263840B/it
Publication of ITMI930605A0 publication Critical patent/ITMI930605A0/it
Priority to EP94104406A priority patent/EP0617957A1/en
Priority to JP6058591A priority patent/JPH0769874A/ja
Priority to FI941447A priority patent/FI941447A/fi
Priority to KR1019940006376A priority patent/KR940021054A/ko
Priority to AU59119/94A priority patent/AU5911994A/en
Priority to US08/220,258 priority patent/US5443842A/en
Publication of ITMI930605A1 publication Critical patent/ITMI930605A1/it
Application granted granted Critical
Publication of IT1263840B publication Critical patent/IT1263840B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

Vengono descritte formulazioni farmaceutiche in forma di capsule ad uso orale, contenenti come principio attivo ubidecarenone, caratterizzate dal fatto che il principio attivo è disperso in una miscela di isopropile miristato o isopropile palmitato con olii di ricino polietossilati, idrogenati o non idrogenati.
ITMI930605A 1993-03-30 1993-03-30 Formulazioni orali di ubidecarenone in forma di capsule IT1263840B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI930605A IT1263840B (it) 1993-03-30 1993-03-30 Formulazioni orali di ubidecarenone in forma di capsule
EP94104406A EP0617957A1 (en) 1993-03-30 1994-03-21 Oral formulations of ubidecarenone in form of capsules
JP6058591A JPH0769874A (ja) 1993-03-30 1994-03-29 カプセル形態のユビデカレノン経口製剤
FI941447A FI941447A (fi) 1993-03-30 1994-03-29 Suun kautta annettavat, kapseleina olevat ubidekarenonivalmisteet
KR1019940006376A KR940021054A (ko) 1993-03-30 1994-03-29 캡슐형 유비데카레논 경구 제제
AU59119/94A AU5911994A (en) 1993-03-30 1994-03-29 Oral formulations of ubidecarenone in the form of capsules
US08/220,258 US5443842A (en) 1993-03-30 1994-03-30 Oral formulations of ubidecarenone in form of capsules

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI930605A IT1263840B (it) 1993-03-30 1993-03-30 Formulazioni orali di ubidecarenone in forma di capsule

Publications (3)

Publication Number Publication Date
ITMI930605A0 ITMI930605A0 (it) 1993-03-30
ITMI930605A1 ITMI930605A1 (it) 1994-09-30
IT1263840B true IT1263840B (it) 1996-09-04

Family

ID=11365545

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI930605A IT1263840B (it) 1993-03-30 1993-03-30 Formulazioni orali di ubidecarenone in forma di capsule

Country Status (7)

Country Link
US (1) US5443842A (it)
EP (1) EP0617957A1 (it)
JP (1) JPH0769874A (it)
KR (1) KR940021054A (it)
AU (1) AU5911994A (it)
FI (1) FI941447A (it)
IT (1) IT1263840B (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10133305B4 (de) 2001-07-12 2004-06-03 Aquanova German Solubilisate Technologies (Agt) Gmbh Ubichinon Konzentrat
JP3822479B2 (ja) 2001-10-10 2006-09-20 株式会社カネカ 還元型補酵素ｑ水溶液の安定化組成
CN101084016A (zh) 2004-04-15 2007-12-05 克艾思马有限公司 能够容易穿透生物学障碍的组合物
CN101119710B (zh) * 2004-11-16 2013-03-27 生物利用股份有限公司 用于营养用途的高浓度自微乳化辅酶q10制剂
US8252326B2 (en) * 2005-06-01 2012-08-28 Catalent Australia Pty Ltd. Self-microemulsifying dosage forms of low solubility active ingredients such as co-enzyme Q10
CN101272769B (zh) * 2005-07-28 2013-04-24 Isp投资有限公司 生物利用度提高的苯醌类化合物
KR101320016B1 (ko) * 2005-12-14 2013-10-29 주식회사 대웅 안정화된 코엔자임ｑ10, 종합 비타민 및 미네랄 성분을함유하는 복합제제
CA2637275C (en) * 2006-01-24 2014-12-09 R-Tech Ueno, Ltd. Pharmaceutical composition comprising a bi-cyclic compound and method for stabilizing the bi-cyclic compound
MY153288A (en) * 2006-06-28 2015-01-29 Hovid Berhad An effective pharmaceutical carrier for poorly bioavailable drugs
WO2008076780A2 (en) * 2006-12-14 2008-06-26 Isp Investments Inc. Amorphous valsartan and the production thereof
WO2008080037A2 (en) * 2006-12-21 2008-07-03 Isp Investments Inc. Carotenoids of enhanced bioavailability
US20080181961A1 (en) * 2007-01-26 2008-07-31 Isp Investments, Inc. Amorphous oxcarbazepine and the production thereof
US10189957B2 (en) * 2007-01-26 2019-01-29 Isp Investments Llc Formulation process method to produce spray dried products
KR100869444B1 (ko) * 2007-07-11 2008-11-18 주식회사 중외제약 유비데카레논을 함유하는 다층정 비타민 복합제제
US20090060993A1 (en) * 2007-09-04 2009-03-05 Joseph Schwarz Solid pharmaceutical composition for enhanced delivery of coenzyme q-10 and ubiquinones
BRPI0918652B1 (pt) 2008-09-17 2021-10-19 Chiasma, Inc. Composição farmacêutica compreendendo um meio hidrofóbico e uma forma sólida que compreende polipeptídeo e sal de ácido graxo de cadeia média, processo de produção da mesma e forma de dosagem oral
EP3253401A4 (en) 2015-02-03 2018-11-21 Chiasma Inc. Method of treating diseases
FR3037246B1 (fr) * 2015-06-09 2017-07-21 Laboratoires Iphym Composition comprenant un extrait de chrysanthellum et de l'ubidecarenone
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5581813A (en) * 1978-12-16 1980-06-20 Nisshin Flour Milling Co Ltd Composition containing coenzyme q10 and its perparation
JPS55153717A (en) * 1979-05-18 1980-11-29 Tokai Kapuseru Kk Preparation of ubidecarenone soft capsule
JPS59148718A (ja) * 1983-02-10 1984-08-25 Fujisawa Pharmaceut Co Ltd ユビデカレノン組成物
DE3588023D1 (de) * 1984-01-28 1995-06-29 Roshdy Ismail Mittel zur Behandlung von Herzerkrankungen.
IT1191608B (it) * 1985-02-01 1988-03-23 Zambon Spa Composizione farmaceutica e forme farmaceutiche che la contengono
US5140021A (en) * 1986-04-16 1992-08-18 Genesis Systems Corporation Method and dosage form for treatment of premenstrual syndrome
JPH0774145B2 (ja) * 1986-12-15 1995-08-09 株式会社資生堂 結晶性薬物含有乳化組成物
GB8630273D0 (en) * 1986-12-18 1987-01-28 Til Medical Ltd Pharmaceutical delivery systems
GB8701332D0 (en) * 1987-01-21 1987-02-25 Lilly Industries Ltd Capsule filling
KR880012221A (ko) * 1987-04-13 1988-11-26 사노 가즈오 에스테르 또는 아미드를 활성성분으로 함유하는 약제 조성물
DE3738236A1 (de) * 1987-11-11 1989-05-24 Euro Celtique Sa Beisskapsel
FI96169C (fi) * 1989-07-10 1996-05-27 Eisai Co Ltd Menetelmä polyprenyyliyhdistettä sisältävän farmaseuttisen koostumuksen valmistamiseksi
IT1250672B (it) * 1991-07-11 1995-04-21 Idb Holding Spa Formulazioni orali di ubidecarenone in soluzione acquosa
US5206219A (en) * 1991-11-25 1993-04-27 Applied Analytical Industries, Inc. Oral compositions of proteinaceous medicaments

Also Published As

Publication number Publication date
JPH0769874A (ja) 1995-03-14
ITMI930605A0 (it) 1993-03-30
KR940021054A (ko) 1994-10-17
FI941447A (fi) 1994-10-01
US5443842A (en) 1995-08-22
FI941447A0 (fi) 1994-03-29
ITMI930605A1 (it) 1994-09-30
EP0617957A1 (en) 1994-10-05
AU5911994A (en) 1994-10-06

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970328