HU230301B1 - Fertőzések enzimes kezelése - Google Patents
Fertőzések enzimes kezelése Download PDFInfo
- Publication number
- HU230301B1 HU230301B1 HU0203402A HUP0203402A HU230301B1 HU 230301 B1 HU230301 B1 HU 230301B1 HU 0203402 A HU0203402 A HU 0203402A HU P0203402 A HUP0203402 A HU P0203402A HU 230301 B1 HU230301 B1 HU 230301B1
- Authority
- HU
- Hungary
- Prior art keywords
- enzyme
- composition
- infection
- lake
- strain
- Prior art date
Links
- 108090000790 Enzymes Proteins 0.000 title claims description 93
- 102000004190 Enzymes Human genes 0.000 title claims description 93
- 208000015181 infectious disease Diseases 0.000 title claims description 45
- 238000011282 treatment Methods 0.000 title claims description 34
- 239000000203 mixture Substances 0.000 claims description 34
- 238000002360 preparation method Methods 0.000 claims description 19
- 241001465754 Metazoa Species 0.000 claims description 14
- 239000003814 drug Substances 0.000 claims description 12
- 150000001720 carbohydrates Chemical class 0.000 claims description 11
- 244000052769 pathogen Species 0.000 claims description 11
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 10
- 235000013305 food Nutrition 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 7
- 230000001717 pathogenic effect Effects 0.000 claims description 6
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 5
- 210000001035 gastrointestinal tract Anatomy 0.000 claims description 5
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 5
- 239000011707 mineral Substances 0.000 claims description 5
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims description 4
- 244000046052 Phaseolus vulgaris Species 0.000 claims description 4
- SRBFZHDQGSBBOR-IOVATXLUSA-N Xylose Natural products O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 4
- 239000004599 antimicrobial Substances 0.000 claims description 4
- 235000013339 cereals Nutrition 0.000 claims description 4
- 239000006260 foam Substances 0.000 claims description 4
- 229940088594 vitamin Drugs 0.000 claims description 4
- 235000013343 vitamin Nutrition 0.000 claims description 4
- 239000011782 vitamin Substances 0.000 claims description 4
- 229930003231 vitamin Natural products 0.000 claims description 4
- 241000233866 Fungi Species 0.000 claims description 3
- 229910019142 PO4 Inorganic materials 0.000 claims description 3
- 235000010582 Pisum sativum Nutrition 0.000 claims description 3
- 240000004713 Pisum sativum Species 0.000 claims description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 3
- 240000008042 Zea mays Species 0.000 claims description 3
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 3
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims description 3
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 3
- 238000009472 formulation Methods 0.000 claims description 3
- 229910052742 iron Inorganic materials 0.000 claims description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 3
- 239000010452 phosphate Substances 0.000 claims description 3
- 206010017964 Gastrointestinal infection Diseases 0.000 claims description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 2
- 235000021307 Triticum Nutrition 0.000 claims description 2
- 244000098338 Triticum aestivum Species 0.000 claims description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 2
- 235000005822 corn Nutrition 0.000 claims description 2
- 208000019836 digestive system infectious disease Diseases 0.000 claims description 2
- -1 dnktdz Natural products 0.000 claims description 2
- 150000002148 esters Chemical class 0.000 claims description 2
- 239000008103 glucose Substances 0.000 claims description 2
- 239000012678 infectious agent Substances 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims description 2
- 229940075554 sorbate Drugs 0.000 claims description 2
- 239000003381 stabilizer Substances 0.000 claims 3
- 244000075850 Avena orientalis Species 0.000 claims 2
- 235000007319 Avena orientalis Nutrition 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 244000052616 bacterial pathogen Species 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 239000007903 gelatin capsule Substances 0.000 claims 2
- 125000000969 xylosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)CO1)* 0.000 claims 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 1
- 241001135931 Anolis Species 0.000 claims 1
- 235000007558 Avena sp Nutrition 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 206010061692 Benign muscle neoplasm Diseases 0.000 claims 1
- 240000007124 Brassica oleracea Species 0.000 claims 1
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 claims 1
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 claims 1
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 claims 1
- 244000045195 Cicer arietinum Species 0.000 claims 1
- 235000010523 Cicer arietinum Nutrition 0.000 claims 1
- 240000005979 Hordeum vulgare Species 0.000 claims 1
- 235000007340 Hordeum vulgare Nutrition 0.000 claims 1
- 102000004882 Lipase Human genes 0.000 claims 1
- 108090001060 Lipase Proteins 0.000 claims 1
- 239000004367 Lipase Substances 0.000 claims 1
- 201000004458 Myoma Diseases 0.000 claims 1
- 206010028851 Necrosis Diseases 0.000 claims 1
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims 1
- 206010037742 Rabies Diseases 0.000 claims 1
- 108020004511 Recombinant DNA Proteins 0.000 claims 1
- 206010039509 Scab Diseases 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- 240000006394 Sorghum bicolor Species 0.000 claims 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 claims 1
- 235000019714 Triticale Nutrition 0.000 claims 1
- 208000025865 Ulcer Diseases 0.000 claims 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 230000002924 anti-infective effect Effects 0.000 claims 1
- 239000003429 antifungal agent Substances 0.000 claims 1
- 229940121375 antifungal agent Drugs 0.000 claims 1
- 125000003289 ascorbyl group Chemical group [H]O[C@@]([H])(C([H])([H])O*)[C@@]1([H])OC(=O)C(O*)=C1O* 0.000 claims 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
- 239000004067 bulking agent Substances 0.000 claims 1
- 239000004464 cereal grain Substances 0.000 claims 1
- 210000003022 colostrum Anatomy 0.000 claims 1
- 235000021277 colostrum Nutrition 0.000 claims 1
- 235000019788 craving Nutrition 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 239000003349 gelling agent Substances 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- ZVQYBVHPCSNWAU-UHFFFAOYSA-N icos-1-enylbenzene Chemical compound CCCCCCCCCCCCCCCCCCC=CC1=CC=CC=C1 ZVQYBVHPCSNWAU-UHFFFAOYSA-N 0.000 claims 1
- 229960000367 inositol Drugs 0.000 claims 1
- 235000019421 lipase Nutrition 0.000 claims 1
- 235000009973 maize Nutrition 0.000 claims 1
- 230000017074 necrotic cell death Effects 0.000 claims 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 235000019640 taste Nutrition 0.000 claims 1
- 241000228158 x Triticosecale Species 0.000 claims 1
- 238000012360 testing method Methods 0.000 description 30
- 230000000694 effects Effects 0.000 description 13
- 238000000034 method Methods 0.000 description 12
- 241000271566 Aves Species 0.000 description 10
- 206010052428 Wound Diseases 0.000 description 10
- 208000027418 Wounds and injury Diseases 0.000 description 10
- 239000002609 medium Substances 0.000 description 10
- 108090000623 proteins and genes Proteins 0.000 description 10
- 239000000126 substance Substances 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- 238000002474 experimental method Methods 0.000 description 9
- 239000000243 solution Substances 0.000 description 9
- 241000287828 Gallus gallus Species 0.000 description 8
- 235000014633 carbohydrates Nutrition 0.000 description 8
- 238000006243 chemical reaction Methods 0.000 description 8
- 235000013330 chicken meat Nutrition 0.000 description 8
- 229940079593 drug Drugs 0.000 description 8
- 230000012010 growth Effects 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 6
- 102000004169 proteins and genes Human genes 0.000 description 6
- 241000699670 Mus sp. Species 0.000 description 5
- 238000003556 assay Methods 0.000 description 5
- 230000005764 inhibitory process Effects 0.000 description 5
- 239000002054 inoculum Substances 0.000 description 5
- 150000003839 salts Chemical class 0.000 description 5
- 230000001580 bacterial effect Effects 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000003651 drinking water Substances 0.000 description 4
- 235000020188 drinking water Nutrition 0.000 description 4
- 238000011049 filling Methods 0.000 description 4
- 239000002244 precipitate Substances 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000009467 reduction Effects 0.000 description 4
- 239000004575 stone Substances 0.000 description 4
- 206010010904 Convulsion Diseases 0.000 description 3
- 241000699666 Mus <mouse, genus> Species 0.000 description 3
- 239000003242 anti bacterial agent Substances 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 229960005475 antiinfective agent Drugs 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 230000001413 cellular effect Effects 0.000 description 3
- 239000011436 cob Substances 0.000 description 3
- 230000003111 delayed effect Effects 0.000 description 3
- 210000002249 digestive system Anatomy 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000002255 enzymatic effect Effects 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 238000000855 fermentation Methods 0.000 description 3
- 230000004151 fermentation Effects 0.000 description 3
- 230000002458 infectious effect Effects 0.000 description 3
- 230000000968 intestinal effect Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000003973 paint Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- BFTGQIQVUVTBJU-UHFFFAOYSA-N 5,6-dihydroimidazo[2,1-c][1,2,4]dithiazole-3-thione Chemical compound C1CN2C(=S)SSC2=N1 BFTGQIQVUVTBJU-UHFFFAOYSA-N 0.000 description 2
- 208000018522 Gastrointestinal disease Diseases 0.000 description 2
- 206010022678 Intestinal infections Diseases 0.000 description 2
- 244000269722 Thea sinensis Species 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 230000002550 fecal effect Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000011081 inoculation Methods 0.000 description 2
- 239000010410 layer Substances 0.000 description 2
- 230000001338 necrotic effect Effects 0.000 description 2
- 239000013642 negative control Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 229960005486 vaccine Drugs 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 101150011516 xlnD gene Proteins 0.000 description 2
- 101150052264 xylA gene Proteins 0.000 description 2
- 101710139410 1-phosphatidylinositol phosphodiesterase Proteins 0.000 description 1
- 241000238876 Acari Species 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- 244000291564 Allium cepa Species 0.000 description 1
- 235000002732 Allium cepa var. cepa Nutrition 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
- 208000031295 Animal disease Diseases 0.000 description 1
- 241000205585 Aquilegia canadensis Species 0.000 description 1
- 241001132374 Asta Species 0.000 description 1
- KUVIULQEHSCUHY-XYWKZLDCSA-N Beclometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(OC(=O)CC)[C@@]1(C)C[C@@H]2O KUVIULQEHSCUHY-XYWKZLDCSA-N 0.000 description 1
- 102100032487 Beta-mannosidase Human genes 0.000 description 1
- 101150111062 C gene Proteins 0.000 description 1
- 101100310222 Caenorhabditis briggsae she-1 gene Proteins 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 description 1
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 description 1
- RAPBNVDSDCTNRC-UHFFFAOYSA-N Chlorobenzilate Chemical compound C=1C=C(Cl)C=CC=1C(O)(C(=O)OCC)C1=CC=C(Cl)C=C1 RAPBNVDSDCTNRC-UHFFFAOYSA-N 0.000 description 1
- 241000272470 Circus Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 239000004866 Hashish Substances 0.000 description 1
- 208000013016 Hypoglycemia Diseases 0.000 description 1
- 206010061217 Infestation Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 108010044467 Isoenzymes Proteins 0.000 description 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 1
- 241001061269 Lestes Species 0.000 description 1
- 240000006240 Linum usitatissimum Species 0.000 description 1
- 235000004431 Linum usitatissimum Nutrition 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 101100001347 Mus musculus Akt1s1 gene Proteins 0.000 description 1
- 241001274216 Naso Species 0.000 description 1
- 206010058803 Oesophageal infection Diseases 0.000 description 1
- 229920006926 PFC Polymers 0.000 description 1
- 241000282320 Panthera leo Species 0.000 description 1
- 201000005702 Pertussis Diseases 0.000 description 1
- 102000006486 Phosphoinositide Phospholipase C Human genes 0.000 description 1
- 108010044302 Phosphoinositide phospholipase C Proteins 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 102100037097 Protein disulfide-isomerase A3 Human genes 0.000 description 1
- 240000001987 Pyrus communis Species 0.000 description 1
- 241000208422 Rhododendron Species 0.000 description 1
- 244000264648 Rhus coriaria Species 0.000 description 1
- 235000013178 Rhus coriaria Nutrition 0.000 description 1
- 241000269821 Scombridae Species 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241000271567 Struthioniformes Species 0.000 description 1
- 239000006180 TBST buffer Substances 0.000 description 1
- 241000656145 Thyrsites atun Species 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 235000005072 Vigna sesquipedalis Nutrition 0.000 description 1
- 244000090207 Vigna sesquipedalis Species 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000005862 Whey Substances 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 108010046377 Whey Proteins Proteins 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 235000013334 alcoholic beverage Nutrition 0.000 description 1
- 238000005275 alloying Methods 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 229940126575 aminoglycoside Drugs 0.000 description 1
- 230000003109 amnesic effect Effects 0.000 description 1
- 238000000540 analysis of variance Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 239000002519 antifouling agent Substances 0.000 description 1
- 229910052785 arsenic Inorganic materials 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 238000013475 authorization Methods 0.000 description 1
- 235000015241 bacon Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 108010055059 beta-Mannosidase Proteins 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 239000011449 brick Substances 0.000 description 1
- 239000012267 brine Substances 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000006315 carbonylation Effects 0.000 description 1
- 238000005810 carbonylation reaction Methods 0.000 description 1
- 229940114116 carminate Drugs 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000007385 chemical modification Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 125000001309 chloro group Chemical group Cl* 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 238000010367 cloning Methods 0.000 description 1
- 239000000701 coagulant Substances 0.000 description 1
- 239000000571 coke Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- FHIVAFMUCKRCQO-UHFFFAOYSA-N diazinon Chemical compound CCOP(=S)(OCC)OC1=CC(C)=NC(C(C)C)=N1 FHIVAFMUCKRCQO-UHFFFAOYSA-N 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 229910052876 emerald Inorganic materials 0.000 description 1
- 239000010976 emerald Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000007824 enzymatic assay Methods 0.000 description 1
- 238000001952 enzyme assay Methods 0.000 description 1
- YQGOJNYOYNNSMM-UHFFFAOYSA-N eosin Chemical compound [Na+].OC(=O)C1=CC=CC=C1C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C(Br)C(O)=C(Br)C=C21 YQGOJNYOYNNSMM-UHFFFAOYSA-N 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000012526 feed medium Substances 0.000 description 1
- 235000019688 fish Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 239000000383 hazardous chemical Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 239000012943 hotmelt Substances 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000004900 laundering Methods 0.000 description 1
- 239000008297 liquid dosage form Substances 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 235000020640 mackerel Nutrition 0.000 description 1
- 240000004308 marijuana Species 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000005272 metallurgy Methods 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004660 morphological change Effects 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 235000021278 navy bean Nutrition 0.000 description 1
- 229910052754 neon Inorganic materials 0.000 description 1
- GKAOGPIIYCISHV-UHFFFAOYSA-N neon atom Chemical compound [Ne] GKAOGPIIYCISHV-UHFFFAOYSA-N 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 229940037201 oris Drugs 0.000 description 1
- 230000008775 paternal effect Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000001175 peptic effect Effects 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 238000004382 potting Methods 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 235000013594 poultry meat Nutrition 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 230000037390 scarring Effects 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000010802 sludge Substances 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
- 239000007909 solid dosage form Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000009987 spinning Methods 0.000 description 1
- 101150008563 spir gene Proteins 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 238000013517 stratification Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 210000005010 torso Anatomy 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 244000000190 yeast pathogen Species 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/04—Phosphoric diester hydrolases (3.1.4)
- C12Y301/04011—Phosphoinositide phospholipase C (3.1.4.11)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01078—Mannan endo-1,4-beta-mannosidase (3.2.1.78), i.e. endo-beta-mannanase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Husbandry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16993599P | 1999-12-10 | 1999-12-10 | |
| US60/169,935 | 1999-12-10 | ||
| PCT/US2000/033466 WO2001041785A2 (en) | 1999-12-10 | 2000-12-08 | Enzyme treatment for infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HUP0203402A2 HUP0203402A2 (hu) | 2003-02-28 |
| HUP0203402A3 HUP0203402A3 (en) | 2004-12-28 |
| HU230301B1 true HU230301B1 (hu) | 2015-12-28 |
Family
ID=22617824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0203402A HU230301B1 (hu) | 1999-12-10 | 2000-12-08 | Fertőzések enzimes kezelése |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US6780628B2 (enExample) |
| EP (1) | EP1239872B1 (enExample) |
| JP (1) | JP4871473B2 (enExample) |
| KR (1) | KR100639746B1 (enExample) |
| CN (3) | CN101327320A (enExample) |
| AR (2) | AR026764A1 (enExample) |
| AT (1) | ATE481981T1 (enExample) |
| AU (1) | AU782831B2 (enExample) |
| BR (1) | BRPI0016231B8 (enExample) |
| CA (1) | CA2394856C (enExample) |
| CL (1) | CL2008000057A1 (enExample) |
| CO (1) | CO5280226A1 (enExample) |
| CR (1) | CR6674A (enExample) |
| CZ (1) | CZ304925B6 (enExample) |
| DE (1) | DE60045010D1 (enExample) |
| DK (1) | DK1239872T3 (enExample) |
| ES (1) | ES2353371T3 (enExample) |
| HU (1) | HU230301B1 (enExample) |
| IL (2) | IL150048A0 (enExample) |
| IN (1) | IN247731B (enExample) |
| MX (1) | MX264033B (enExample) |
| MY (1) | MY124714A (enExample) |
| NZ (1) | NZ519404A (enExample) |
| PH (1) | PH12000003381B1 (enExample) |
| PL (1) | PL203054B1 (enExample) |
| PT (1) | PT1239872E (enExample) |
| RU (1) | RU2272419C2 (enExample) |
| SK (1) | SK287956B6 (enExample) |
| TW (1) | TWI255189B (enExample) |
| UA (1) | UA78486C2 (enExample) |
| WO (1) | WO2001041785A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA78486C2 (uk) | 1999-12-10 | 2007-04-10 | Хемджен Корпорейшн | Композиція для перорального введення птахам та тваринам для лікування або зниження ризику інфекції травного тракту (варіанти), її застосування (варіанти) та спосіб лікування або зниження ризику інфекцій травного тракту (варіанти) |
| US7247299B2 (en) * | 2002-11-27 | 2007-07-24 | Kemin Industries, Inc. | Antimicrobial compounds from Bacillus subtilis for use against animal and human pathogens |
| US7566447B2 (en) * | 2003-05-15 | 2009-07-28 | Iogenetics, Llc | Biocides |
| US20050014932A1 (en) * | 2003-05-15 | 2005-01-20 | Iogenetics, Llc | Targeted biocides |
| US8394379B2 (en) * | 2003-05-15 | 2013-03-12 | Iogenetics, Llc | Targeted cryptosporidium biocides |
| US8703134B2 (en) | 2003-05-15 | 2014-04-22 | Iogenetics, Llc | Targeted cryptosporidium biocides |
| US8388951B2 (en) | 2003-07-14 | 2013-03-05 | Cls Therapeutics Limited | Method for treating systemic DNA mutation disease |
| US9248166B2 (en) | 2003-07-14 | 2016-02-02 | Cls Therapeutics Limited | Method for treating oncological diseases |
| US8431123B2 (en) | 2003-07-14 | 2013-04-30 | Cls Therapeutics Limited | Method for treating systemic bacterial, fungal and protozoan infection |
| US8710012B2 (en) | 2003-07-14 | 2014-04-29 | Cls Therapeutics Limited | Method for treating oncological diseases |
| CA2585017A1 (en) * | 2004-10-20 | 2006-12-14 | Iogenetics, Llc | Biocides |
| EP1880733A4 (en) | 2005-04-25 | 2009-08-12 | Genkin Dmitry Dmitrievich | Method for increasing longevity of a human being and animals |
| MY145870A (en) * | 2005-12-15 | 2012-05-15 | Lilly Co Eli | Enzymes for reduced immunological stress |
| EP1981355B1 (en) * | 2006-01-23 | 2018-03-14 | Hill's Pet Nutrition, Inc. | Methods for reducing food intake and controlling the weight of animals |
| RU2319481C1 (ru) * | 2006-10-20 | 2008-03-20 | Илья Николаевич Медведев | Способ коррекции уровня оксида азота в крови поросят с острым катаральным энтеритом |
| KR20090087095A (ko) | 2006-11-28 | 2009-08-14 | 드미트리 드미트리에비치 겐킨 | 조직의 세포외공간에서 증가된 데옥시리보핵산 함량과 관련된 인간 질병을 치료하는 방법 및 이 방법을 수행하기 위한 약학 제제 |
| BRPI0812346B1 (pt) * | 2007-06-08 | 2019-01-22 | Australian Poultry Crc Pty Ltd | célula hospedeira, método para a produção de um polipeptídeo isolado, composição, vacinas, método de atenuação da virulência de uma bactéria, método para determinar se um indivíduo foi exposto a um patógeno e uso da célula hospedeira, das vacinas ou da bactéria |
| RU2440369C2 (ru) * | 2007-08-03 | 2012-01-20 | Бёрингер Ингельхайм Ветмедика Гмбх | ГЕНЫ И БЕЛКИ Brachyspira hyodysenteriae И ИХ ПРИМЕНЕНИЕ |
| RU2495098C2 (ru) * | 2007-12-20 | 2013-10-10 | ДАНИСКО ЮЖс ИНК. | Способ ферментативного удаления биопленки, композиция и набор |
| WO2009100456A2 (en) * | 2008-02-08 | 2009-08-13 | Prothera, Inc. | Inhibition and treatment of gastrointestinal biofilms |
| RU2380901C1 (ru) * | 2008-08-13 | 2010-02-10 | Государственное научное учреждение Ставропольский научно-исследовательский институт животноводства и кормопроизводства Российской академии сельскохозяйственных наук | Способ повышения однородности стада, живой массы, конверсии корма при выращивании цыплят |
| CA2864887C (en) | 2012-02-16 | 2017-04-25 | Eli Lilly And Company | Methods and compositions for reducing the environmental impact of animal waste |
| US10617743B2 (en) | 2014-06-19 | 2020-04-14 | Cls Therapeutics Limited | Method to improve safety and efficacy of anti-cancer therapy |
| TWI656872B (zh) | 2014-11-13 | 2019-04-21 | 美商益農美國公司 | 甲基鹽黴素於豬飼料中之抗病毒效果 |
| RU2726131C2 (ru) | 2015-05-22 | 2020-07-09 | Дмитрий Дмитриевич Генкин | Внеклеточная днк в качестве терапевтической мишени при нейродегенерации |
| CN106119221A (zh) * | 2016-06-28 | 2016-11-16 | 浙江省农业科学院 | 磷脂酰肌醇特异性磷脂酶c基因、载体、工程菌及应用 |
| CN106318925B (zh) * | 2016-08-19 | 2021-04-02 | 浙江省农业科学院 | 利用枯草芽孢杆菌高效表达pi-plc基因的方法 |
| CN106615691B (zh) * | 2016-10-11 | 2019-07-02 | 上海国龙生物技术集团有限公司 | 一种抗感染酶复合剂及其在饲料中的应用 |
| US10501730B2 (en) * | 2017-05-30 | 2019-12-10 | Ab Enzymes Oy | Mannanase variants |
| US11905522B2 (en) | 2018-01-16 | 2024-02-20 | Cls Therapeutics Limited | Treatment of diseases by liver expression of an enzyme which has a deoxyribonuclease (DNase) activity |
| US20210011027A1 (en) * | 2018-03-02 | 2021-01-14 | Evonik Operations Gmbh | In vitro method for detecting intestinal barrier failure in animals by determining ovotransferrin |
| MX2021006917A (es) | 2018-12-14 | 2021-07-07 | Evonik Operations Gmbh | Procedimiento in vitro para la deteccion de disbiosis intestinal aviar. |
| RU2720471C1 (ru) * | 2019-03-21 | 2020-04-30 | Федеральное Государственное бюджетное научное учреждение "Федеральный научный центр биологических систем и агротехнологий российской академии наук" | Кормовая добавка для цыплят-бройлеров |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1509866A (en) | 1975-06-10 | 1978-05-04 | Johnson & Johnson | Enteric coated digestive enzyme compositions |
| JPS5534039A (en) | 1978-08-30 | 1980-03-10 | Hiroo Ikezawa | Preparation of phsophatidylinositol phospholipase c from bacillus thuringiensis |
| ATE68524T1 (de) | 1985-07-09 | 1991-11-15 | Quadrant Bioresources Ltd | Beschuetzung von proteinen und aehnlichem. |
| US5049379A (en) | 1987-07-27 | 1991-09-17 | Wisconsin Alumni Research Foundation | Fungicidal toxin and method and inoculum for controlling root rot and damping off |
| US4877738A (en) | 1986-07-25 | 1989-10-31 | Wisconsin Alumni Research Foundation | Biological control of damping off and root rot and inoculum preparation therefor |
| JPH0338530A (ja) * | 1989-07-03 | 1991-02-19 | Ajinomoto Co Inc | 抗真菌剤 |
| US5487897A (en) * | 1989-07-24 | 1996-01-30 | Atrix Laboratories, Inc. | Biodegradable implant precursor |
| JP3608620B2 (ja) * | 1990-05-29 | 2005-01-12 | ケムジエン・コーポレイシヨン | ヘミセルロース含有食品及び動物用飼料のエネルギー効率を改善するためのヘミセルラーゼ補充物 |
| EP0477739A3 (en) * | 1990-09-27 | 1992-12-09 | F. Hoffmann-La Roche Ag | Glycosyl-phosphatidylinositol-specific phospholipase d |
| WO1993001800A1 (en) * | 1991-07-24 | 1993-02-04 | Thomas Sai Ying Ko | Therapeutic compositions and methods |
| JPH07184642A (ja) * | 1993-12-27 | 1995-07-25 | Toagosei Co Ltd | ホスホリパーゼｃの生産方法 |
| EP0743017B1 (en) * | 1995-05-15 | 2004-09-29 | DSM IP Assets B.V. | Application of phospholipases in animal feed |
| MY134684A (en) * | 1995-05-15 | 2007-12-31 | Gist Brocades Bv | Application of phospholipases in animal feed |
| JPH08332032A (ja) * | 1995-06-12 | 1996-12-17 | Showa Denko Kk | 動物経口物用酵素剤及びその用途 |
| JP3914585B2 (ja) * | 1995-10-19 | 2007-05-16 | イーエヌ大塚製薬株式会社 | マクロファージ一酸化窒素産生亢進剤 |
| CN1092495C (zh) * | 1996-05-03 | 2002-10-16 | 开姆根有限公司 | 半纤维素酶在低热焓饲料中的应用 |
| US6162473A (en) * | 1996-05-03 | 2000-12-19 | Chemgen Corporation | Hemicellulase use in feeds with low caloric content |
| JPH1045581A (ja) * | 1996-07-29 | 1998-02-17 | Hideyo Yamaguchi | 好中球機能低下抑制剤又は感染防御剤 |
| WO1998018912A1 (en) * | 1996-10-31 | 1998-05-07 | Novo Nordisk A/S | Novel phospholipase, production and use thereof |
| JP2002527046A (ja) * | 1998-10-15 | 2002-08-27 | デーエスエム・ナムローゼ・フェンノートシャップ | 動物飼料中における抗微生物酵素 |
| UA78486C2 (uk) | 1999-12-10 | 2007-04-10 | Хемджен Корпорейшн | Композиція для перорального введення птахам та тваринам для лікування або зниження ризику інфекції травного тракту (варіанти), її застосування (варіанти) та спосіб лікування або зниження ризику інфекцій травного тракту (варіанти) |
| US20020116028A1 (en) * | 2001-02-20 | 2002-08-22 | Wilson Greatbatch | MRI-compatible pacemaker with pulse carrying photonic catheter providing VOO functionality |
-
2000
- 2000-08-12 UA UA2002075677A patent/UA78486C2/uk unknown
- 2000-12-07 CO CO00093684A patent/CO5280226A1/es not_active Application Discontinuation
- 2000-12-07 AR ARP000106541A patent/AR026764A1/es not_active Application Discontinuation
- 2000-12-08 CN CNA2008101259037A patent/CN101327320A/zh active Pending
- 2000-12-08 US US09/731,971 patent/US6780628B2/en not_active Expired - Lifetime
- 2000-12-08 WO PCT/US2000/033466 patent/WO2001041785A2/en not_active Ceased
- 2000-12-08 CN CN00818851A patent/CN1433319A/zh active Pending
- 2000-12-08 EP EP00989240A patent/EP1239872B1/en not_active Expired - Lifetime
- 2000-12-08 DK DK00989240.7T patent/DK1239872T3/da active
- 2000-12-08 MY MYPI20005779A patent/MY124714A/en unknown
- 2000-12-08 JP JP2001543129A patent/JP4871473B2/ja not_active Expired - Lifetime
- 2000-12-08 CZ CZ2002-2007A patent/CZ304925B6/cs not_active IP Right Cessation
- 2000-12-08 PH PH12000003381A patent/PH12000003381B1/en unknown
- 2000-12-08 SK SK826-2002A patent/SK287956B6/sk not_active IP Right Cessation
- 2000-12-08 NZ NZ519404A patent/NZ519404A/en not_active IP Right Cessation
- 2000-12-08 KR KR1020027007363A patent/KR100639746B1/ko not_active Expired - Lifetime
- 2000-12-08 ES ES00989240T patent/ES2353371T3/es not_active Expired - Lifetime
- 2000-12-08 HU HU0203402A patent/HU230301B1/hu unknown
- 2000-12-08 AU AU25776/01A patent/AU782831B2/en not_active Expired
- 2000-12-08 CA CA2394856A patent/CA2394856C/en not_active Expired - Lifetime
- 2000-12-08 RU RU2002118694/13A patent/RU2272419C2/ru active
- 2000-12-08 AT AT00989240T patent/ATE481981T1/de active
- 2000-12-08 DE DE60045010T patent/DE60045010D1/de not_active Expired - Lifetime
- 2000-12-08 CN CN201110076924.6A patent/CN102172262B/zh not_active Expired - Lifetime
- 2000-12-08 MX MXPA02005735 patent/MX264033B/es active IP Right Grant
- 2000-12-08 PT PT00989240T patent/PT1239872E/pt unknown
- 2000-12-08 IL IL15004800A patent/IL150048A0/xx unknown
- 2000-12-08 BR BRPI0016231A patent/BRPI0016231B8/pt not_active IP Right Cessation
- 2000-12-08 PL PL356175A patent/PL203054B1/pl unknown
-
2001
- 2001-03-07 TW TW089126252A patent/TWI255189B/zh not_active IP Right Cessation
-
2002
- 2002-06-05 IL IL150048A patent/IL150048A/en active IP Right Grant
- 2002-06-06 IN IN585DE2002 patent/IN247731B/en unknown
- 2002-06-07 CR CR6674A patent/CR6674A/es unknown
-
2004
- 2004-05-28 US US10/855,416 patent/US7723091B2/en not_active Expired - Lifetime
-
2008
- 2008-01-09 CL CL200800057A patent/CL2008000057A1/es unknown
-
2013
- 2013-01-24 AR ARP130100218A patent/AR089799A2/es not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Krishnani et al. | Metallic and non-metallic nanoparticles from plant, animal, and fisheries wastes: potential and valorization for application in agriculture | |
| JP4704377B2 (ja) | 発酵及び培養方法、植物発酵エキス、植物発酵エキス末並びに該植物発酵エキス配合物 | |
| ES2613805T3 (es) | Composición de bacillus resistente a la bilis | |
| HU228503B1 (hu) | Gombaölõ heterociklusos aromás amidok, ezeket tartalmazó készítmények és eljárás alkalmazásukra | |
| BR112019007616A2 (pt) | composição de alimentação para prevenir ou tratar doença de necrose hepatopancreática aguda (ahpnd) ou síndrome da mancha branca (wss) que compreende uma cepa de bacillus subtilis, uma cepa de bacillus pumilus, e uma cepa de bacillus licheniformis como ingredientes ativos | |
| CN104068217B (zh) | 一种牛用抗霉菌毒素饲料添加剂 | |
| CN109561712A (zh) | 直接喂饲的微生物 | |
| CN107266183A (zh) | 鸡粪有机肥及其制备方法 | |
| RU2437563C1 (ru) | Пробиотическая кормовая добавка | |
| WO2017031371A1 (en) | Formulations and methods for promoting honeybee health | |
| CN102513174A (zh) | 一种小麦调质灭菌方法 | |
| Sudpraseart et al. | Efficacy of Rhodobacter sphaeroides TISTR 1529 on the growth performance, immune response, and amino acid profile of Pacific whiteleg shrimp, Penaeus vannamei | |
| CN106577480A (zh) | 一种提高黄牛抗病力的养殖方法 | |
| KR101773762B1 (ko) | 비특이성 면역증강제 조성물 및 그 제조방법, 그리고 그 용도 | |
| CN101708187B (zh) | 一种用于防治水产动物水霉病的干粉制剂及其制备方法 | |
| CN104304169A (zh) | 有机富硒肉猪的养殖方法 | |
| US12016334B2 (en) | Composition comprising sulphated galactose, and implementations thereof | |
| KR100939985B1 (ko) | 술지게미를 이용한 가축사료 조성물 및 그 제조방법 | |
| CN109803669A (zh) | 用于抑制生物膜沉积和产生的组合物和方法 | |
| JP4052535B2 (ja) | 動物用薬剤及び動物用飼料 | |
| CN106615922A (zh) | 一种降低肉鸡包涵体肝炎发病率的饲料 | |
| CN105725013A (zh) | 一种无色的低糖型氨基酸饮品及其制备工艺 | |
| CN108740497A (zh) | 一种提高蛋鸡肠道健康状态的饲料添加剂及其制备方法 | |
| CN108850640A (zh) | 表达人溶菌酶的毕赤酵母发酵产品在肉鸡饲料添加剂中的应用 | |
| CN105920033A (zh) | 一种防治腹泻的口服纳米蒙脱石混悬液制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB9A | Succession in title |
Owner name: ELI LILLY AND COMPANY, US Free format text: FORMER OWNER(S): CHEMGEN CORPORATION, US |
|
| FH91 | Appointment of a representative |
Representative=s name: S.B.G. & K. SZABADALMI UEGYVIVOEI IRODA, HU |
|
| GB9A | Succession in title |
Owner name: ELANCO US INC., US Free format text: FORMER OWNER(S): CHEMGEN CORPORATION, US; ELI LILLY AND COMPANY, US |
|
| FH91 | Appointment of a representative |
Free format text: FORMER REPRESENTATIVE(S): SBGK SZABADALMI UEGYVIVOEI IRODA, HU Representative=s name: SBGK SZABADALMI UEGYVIVOEI IRODA, HU |
|
| FH92 | Termination of representative |
Representative=s name: SBGK SZABADALMI UEGYVIVOEI IRODA, HU |