KR100639746B1 - 감염에 대한 효소 치료법 - Google Patents

감염에 대한 효소 치료법 Download PDF

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Publication number
KR100639746B1
KR100639746B1 KR1020027007363A KR20027007363A KR100639746B1 KR 100639746 B1 KR100639746 B1 KR 100639746B1 KR 1020027007363 A KR1020027007363 A KR 1020027007363A KR 20027007363 A KR20027007363 A KR 20027007363A KR 100639746 B1 KR100639746 B1 KR 100639746B1
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KR
South Korea
Prior art keywords
enzyme
composition
infection
feed
plc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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KR1020027007363A
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English (en)
Korean (ko)
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KR20020069204A (ko
Inventor
데이비드 엠. 앤더슨
린 리우
훔그-유 시아오
더글라스 더블유. 포지
Original Assignee
켐젠 코포레이션
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22617824&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100639746(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 켐젠 코포레이션 filed Critical 켐젠 코포레이션
Publication of KR20020069204A publication Critical patent/KR20020069204A/ko
Application granted granted Critical
Publication of KR100639746B1 publication Critical patent/KR100639746B1/ko
Assigned to 일라이 릴리 앤드 캄파니 reassignment 일라이 릴리 앤드 캄파니 권리의 전부이전등록 Assignors: 켐젠 코포레이션
Assigned to 엘랑코 유에스 인코포레이티드 reassignment 엘랑코 유에스 인코포레이티드 권리의 전부이전등록 Assignors: 일라이 릴리 앤드 캄파니
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/04—Phosphoric diester hydrolases (3.1.4)
    • C12Y301/04011—Phosphoinositide phospholipase C (3.1.4.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01078—Mannan endo-1,4-beta-mannosidase (3.2.1.78), i.e. endo-beta-mannanase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Husbandry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
KR1020027007363A 1999-12-10 2000-12-08 감염에 대한 효소 치료법 Expired - Lifetime KR100639746B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16993599P 1999-12-10 1999-12-10
US60/169,935 1999-12-10

Publications (2)

Publication Number Publication Date
KR20020069204A KR20020069204A (ko) 2002-08-29
KR100639746B1 true KR100639746B1 (ko) 2006-10-30

Family

ID=22617824

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027007363A Expired - Lifetime KR100639746B1 (ko) 1999-12-10 2000-12-08 감염에 대한 효소 치료법

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Country Link
US (2) US6780628B2 (enExample)
EP (1) EP1239872B1 (enExample)
JP (1) JP4871473B2 (enExample)
KR (1) KR100639746B1 (enExample)
CN (3) CN101327320A (enExample)
AR (2) AR026764A1 (enExample)
AT (1) ATE481981T1 (enExample)
AU (1) AU782831B2 (enExample)
BR (1) BRPI0016231B8 (enExample)
CA (1) CA2394856C (enExample)
CL (1) CL2008000057A1 (enExample)
CO (1) CO5280226A1 (enExample)
CR (1) CR6674A (enExample)
CZ (1) CZ304925B6 (enExample)
DE (1) DE60045010D1 (enExample)
DK (1) DK1239872T3 (enExample)
ES (1) ES2353371T3 (enExample)
HU (1) HU230301B1 (enExample)
IL (2) IL150048A0 (enExample)
IN (1) IN247731B (enExample)
MX (1) MX264033B (enExample)
MY (1) MY124714A (enExample)
NZ (1) NZ519404A (enExample)
PH (1) PH12000003381B1 (enExample)
PL (1) PL203054B1 (enExample)
PT (1) PT1239872E (enExample)
RU (1) RU2272419C2 (enExample)
SK (1) SK287956B6 (enExample)
TW (1) TWI255189B (enExample)
UA (1) UA78486C2 (enExample)
WO (1) WO2001041785A2 (enExample)

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UA78486C2 (uk) 1999-12-10 2007-04-10 Хемджен Корпорейшн Композиція для перорального введення птахам та тваринам для лікування або зниження ризику інфекції травного тракту (варіанти), її застосування (варіанти) та спосіб лікування або зниження ризику інфекцій травного тракту (варіанти)
US7247299B2 (en) * 2002-11-27 2007-07-24 Kemin Industries, Inc. Antimicrobial compounds from Bacillus subtilis for use against animal and human pathogens
US7566447B2 (en) * 2003-05-15 2009-07-28 Iogenetics, Llc Biocides
US20050014932A1 (en) * 2003-05-15 2005-01-20 Iogenetics, Llc Targeted biocides
US8394379B2 (en) * 2003-05-15 2013-03-12 Iogenetics, Llc Targeted cryptosporidium biocides
US8703134B2 (en) 2003-05-15 2014-04-22 Iogenetics, Llc Targeted cryptosporidium biocides
US8388951B2 (en) 2003-07-14 2013-03-05 Cls Therapeutics Limited Method for treating systemic DNA mutation disease
US9248166B2 (en) 2003-07-14 2016-02-02 Cls Therapeutics Limited Method for treating oncological diseases
US8431123B2 (en) 2003-07-14 2013-04-30 Cls Therapeutics Limited Method for treating systemic bacterial, fungal and protozoan infection
US8710012B2 (en) 2003-07-14 2014-04-29 Cls Therapeutics Limited Method for treating oncological diseases
CA2585017A1 (en) * 2004-10-20 2006-12-14 Iogenetics, Llc Biocides
EP1880733A4 (en) 2005-04-25 2009-08-12 Genkin Dmitry Dmitrievich Method for increasing longevity of a human being and animals
MY145870A (en) * 2005-12-15 2012-05-15 Lilly Co Eli Enzymes for reduced immunological stress
EP1981355B1 (en) * 2006-01-23 2018-03-14 Hill's Pet Nutrition, Inc. Methods for reducing food intake and controlling the weight of animals
RU2319481C1 (ru) * 2006-10-20 2008-03-20 Илья Николаевич Медведев Способ коррекции уровня оксида азота в крови поросят с острым катаральным энтеритом
KR20090087095A (ko) 2006-11-28 2009-08-14 드미트리 드미트리에비치 겐킨 조직의 세포외공간에서 증가된 데옥시리보핵산 함량과 관련된 인간 질병을 치료하는 방법 및 이 방법을 수행하기 위한 약학 제제
BRPI0812346B1 (pt) * 2007-06-08 2019-01-22 Australian Poultry Crc Pty Ltd célula hospedeira, método para a produção de um polipeptídeo isolado, composição, vacinas, método de atenuação da virulência de uma bactéria, método para determinar se um indivíduo foi exposto a um patógeno e uso da célula hospedeira, das vacinas ou da bactéria
RU2440369C2 (ru) * 2007-08-03 2012-01-20 Бёрингер Ингельхайм Ветмедика Гмбх ГЕНЫ И БЕЛКИ Brachyspira hyodysenteriae И ИХ ПРИМЕНЕНИЕ
RU2495098C2 (ru) * 2007-12-20 2013-10-10 ДАНИСКО ЮЖс ИНК. Способ ферментативного удаления биопленки, композиция и набор
WO2009100456A2 (en) * 2008-02-08 2009-08-13 Prothera, Inc. Inhibition and treatment of gastrointestinal biofilms
RU2380901C1 (ru) * 2008-08-13 2010-02-10 Государственное научное учреждение Ставропольский научно-исследовательский институт животноводства и кормопроизводства Российской академии сельскохозяйственных наук Способ повышения однородности стада, живой массы, конверсии корма при выращивании цыплят
CA2864887C (en) 2012-02-16 2017-04-25 Eli Lilly And Company Methods and compositions for reducing the environmental impact of animal waste
US10617743B2 (en) 2014-06-19 2020-04-14 Cls Therapeutics Limited Method to improve safety and efficacy of anti-cancer therapy
TWI656872B (zh) 2014-11-13 2019-04-21 美商益農美國公司 甲基鹽黴素於豬飼料中之抗病毒效果
RU2726131C2 (ru) 2015-05-22 2020-07-09 Дмитрий Дмитриевич Генкин Внеклеточная днк в качестве терапевтической мишени при нейродегенерации
CN106119221A (zh) * 2016-06-28 2016-11-16 浙江省农业科学院 磷脂酰肌醇特异性磷脂酶c基因、载体、工程菌及应用
CN106318925B (zh) * 2016-08-19 2021-04-02 浙江省农业科学院 利用枯草芽孢杆菌高效表达pi-plc基因的方法
CN106615691B (zh) * 2016-10-11 2019-07-02 上海国龙生物技术集团有限公司 一种抗感染酶复合剂及其在饲料中的应用
US10501730B2 (en) * 2017-05-30 2019-12-10 Ab Enzymes Oy Mannanase variants
US11905522B2 (en) 2018-01-16 2024-02-20 Cls Therapeutics Limited Treatment of diseases by liver expression of an enzyme which has a deoxyribonuclease (DNase) activity
US20210011027A1 (en) * 2018-03-02 2021-01-14 Evonik Operations Gmbh In vitro method for detecting intestinal barrier failure in animals by determining ovotransferrin
MX2021006917A (es) 2018-12-14 2021-07-07 Evonik Operations Gmbh Procedimiento in vitro para la deteccion de disbiosis intestinal aviar.
RU2720471C1 (ru) * 2019-03-21 2020-04-30 Федеральное Государственное бюджетное научное учреждение "Федеральный научный центр биологических систем и агротехнологий российской академии наук" Кормовая добавка для цыплят-бройлеров

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Also Published As

Publication number Publication date
CR6674A (es) 2007-02-22
WO2001041785A2 (en) 2001-06-14
BR0016231A (pt) 2003-06-24
IN247731B (enExample) 2011-05-13
DK1239872T3 (da) 2010-10-25
CN102172262B (zh) 2014-03-05
CL2008000057A1 (es) 2008-03-14
ES2353371T3 (es) 2011-03-01
JP2003520207A (ja) 2003-07-02
IN2002DE00585A (enExample) 2009-03-20
PL203054B1 (pl) 2009-08-31
TWI255189B (en) 2006-05-21
MXPA02005735A (es) 2003-10-14
CZ20022007A3 (cs) 2002-11-13
DE60045010D1 (de) 2010-11-04
AR026764A1 (es) 2003-02-26
CA2394856C (en) 2011-05-10
US20040223961A1 (en) 2004-11-11
HUP0203402A2 (hu) 2003-02-28
IL150048A0 (en) 2002-12-01
PH12000003381B1 (en) 2010-04-16
BRPI0016231B1 (pt) 2016-10-04
MY124714A (en) 2006-06-30
SK287956B6 (sk) 2012-07-03
US7723091B2 (en) 2010-05-25
CN1433319A (zh) 2003-07-30
AU2577601A (en) 2001-06-18
US6780628B2 (en) 2004-08-24
RU2272419C2 (ru) 2006-03-27
HU230301B1 (hu) 2015-12-28
CZ304925B6 (cs) 2015-01-28
CN101327320A (zh) 2008-12-24
EP1239872B1 (en) 2010-09-22
BRPI0016231B8 (pt) 2021-05-25
MX264033B (es) 2009-01-22
NZ519404A (en) 2004-05-28
AU782831B2 (en) 2005-09-01
AR089799A2 (es) 2014-09-17
ATE481981T1 (de) 2010-10-15
PL356175A1 (en) 2004-06-14
SK8262002A3 (en) 2002-12-03
CN102172262A (zh) 2011-09-07
IL150048A (en) 2016-09-29
KR20020069204A (ko) 2002-08-29
PT1239872E (pt) 2010-12-03
HUP0203402A3 (en) 2004-12-28
UA78486C2 (uk) 2007-04-10
CO5280226A1 (es) 2003-05-30
JP4871473B2 (ja) 2012-02-08
EP1239872A2 (en) 2002-09-18
CA2394856A1 (en) 2001-06-14
WO2001041785A3 (en) 2002-01-24
US20020048576A1 (en) 2002-04-25

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