HRP20100644T1 - Cijepivo kombinacije peptida protiv alergije na macke - Google Patents
Cijepivo kombinacije peptida protiv alergije na macke Download PDFInfo
- Publication number
- HRP20100644T1 HRP20100644T1 HR20100644T HRP20100644T HRP20100644T1 HR P20100644 T1 HRP20100644 T1 HR P20100644T1 HR 20100644 T HR20100644 T HR 20100644T HR P20100644 T HRP20100644 T HR P20100644T HR P20100644 T1 HRP20100644 T1 HR P20100644T1
- Authority
- HR
- Croatia
- Prior art keywords
- composition
- polypeptide
- prevention
- treatment
- seq
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract 23
- 241000282326 Felis catus Species 0.000 title claims abstract 11
- 206010020751 Hypersensitivity Diseases 0.000 title claims abstract 10
- 208000026935 allergic disease Diseases 0.000 title claims abstract 10
- 230000007815 allergy Effects 0.000 title claims abstract 10
- 229960005486 vaccine Drugs 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract 19
- 239000000203 mixture Substances 0.000 claims abstract 17
- 229920001184 polypeptide Polymers 0.000 claims 15
- 102000040430 polynucleotide Human genes 0.000 claims 8
- 108091033319 polynucleotide Proteins 0.000 claims 8
- 239000002157 polynucleotide Substances 0.000 claims 8
- 230000002265 prevention Effects 0.000 claims 8
- 239000000047 product Substances 0.000 claims 5
- 210000001744 T-lymphocyte Anatomy 0.000 claims 4
- 239000013598 vector Substances 0.000 claims 4
- 239000013566 allergen Substances 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 230000005867 T cell response Effects 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 239000004475 Arginine Substances 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 230000021736 acetylation Effects 0.000 claims 1
- 238000006640 acetylation reaction Methods 0.000 claims 1
- 230000002009 allergenic effect Effects 0.000 claims 1
- 230000000172 allergic effect Effects 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000009435 amidation Effects 0.000 claims 1
- 238000007112 amidation reaction Methods 0.000 claims 1
- 150000001412 amines Chemical group 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 230000013595 glycosylation Effects 0.000 claims 1
- 238000006206 glycosylation reaction Methods 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 230000026731 phosphorylation Effects 0.000 claims 1
- 238000006366 phosphorylation reaction Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 230000004044 response Effects 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56977—HLA or MHC typing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/577—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0710529.9A GB0710529D0 (en) | 2007-06-01 | 2007-06-01 | Vaccine |
| PCT/GB2008/001827 WO2008145998A1 (fr) | 2007-06-01 | 2008-05-30 | Combinaisons de vaccin contre une allergie aux chats |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20100644T1 true HRP20100644T1 (hr) | 2011-01-31 |
Family
ID=38289716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20100644T HRP20100644T1 (hr) | 2007-06-01 | 2010-11-24 | Cijepivo kombinacije peptida protiv alergije na macke |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US8551492B2 (fr) |
| EP (3) | EP2079481B2 (fr) |
| JP (2) | JP5366936B2 (fr) |
| CN (2) | CN104027801A (fr) |
| AT (1) | ATE481984T1 (fr) |
| AU (1) | AU2008256524B2 (fr) |
| CA (1) | CA2689260C (fr) |
| CY (1) | CY1110980T1 (fr) |
| DE (1) | DE602008002693D1 (fr) |
| DK (1) | DK2079481T4 (fr) |
| ES (2) | ES2353360T5 (fr) |
| GB (1) | GB0710529D0 (fr) |
| HK (1) | HK1132935A1 (fr) |
| HR (1) | HRP20100644T1 (fr) |
| PL (1) | PL2079481T3 (fr) |
| PT (1) | PT2079481E (fr) |
| SI (1) | SI2079481T1 (fr) |
| WO (2) | WO2008146003A1 (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0710529D0 (en) | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
| AU2008288283B2 (en) | 2007-08-15 | 2013-01-31 | Circassia Limited | Peptides for desensibilization against allergens |
| DK2153841T4 (en) | 2008-08-15 | 2016-02-15 | Circassia Ltd | Vaccine comprising Amb a 1 peptides for use in the treatment of ambrosieallergi |
| EP2331124A1 (fr) | 2008-08-15 | 2011-06-15 | Circassia Limited | Peptide de l antigène des cellules t d allergène destiné à stimuler la production d il-10 |
| GB0821806D0 (en) | 2008-11-28 | 2009-01-07 | Circassia Ltd | Compositions with reduced dimer formation |
| PL2393830T3 (pl) | 2009-02-05 | 2015-07-31 | Circassia Ltd | Peptydy traw dla szczepionki |
| GB201002559D0 (en) * | 2010-02-15 | 2010-03-31 | Circassia Ltd | Birch peptides for vaccine |
| JO3820B1 (ar) | 2012-05-03 | 2021-01-31 | Regeneron Pharma | أجسام مضادة بشرية لـ fel d1وطرق لاستخدامها |
| GB201208293D0 (en) * | 2012-05-11 | 2012-06-20 | Circassia Ltd | Hydrochlorice salt of peptide |
| BR112015009883A2 (pt) | 2012-10-30 | 2017-08-22 | Univ Monash | Novas moléculas imunoterapêuticas e os usos das mesmas |
| CA2922113C (fr) | 2013-08-23 | 2023-05-23 | Regeneron Pharmaceuticals, Inc. | Tests diagnostiques et methodes pour evaluer l'innocuite, l'efficacite ou le resultat d'une immunotherapie specifique de l'allergene (its) |
| WO2015042664A1 (fr) | 2013-09-25 | 2015-04-02 | Monash University | Nouvelle composition immunothérapeutique et utilisations associées |
| GB2523399B (en) | 2014-02-25 | 2019-03-13 | Orban Tihamer | A composition comprising ten overlapping peptide fragments of the entire preproinsulin sequence |
| GB2559499A (en) * | 2014-02-25 | 2018-08-08 | Orban Tihamer | Immunomodulatory therapy for type 1 diabetes mellitus autoimmunity |
| EP3355917A1 (fr) * | 2015-09-30 | 2018-08-08 | Boehringer Ingelheim Vetmedica GmbH | Molécules de transport d'antigène modulaire améliorées et leurs utilisations chez des animaux |
| US20190070287A1 (en) * | 2016-02-12 | 2019-03-07 | Virtici, Llc | Tolerance therapeutic for treating polypeptide induced immune activation |
| US11352417B2 (en) | 2016-12-22 | 2022-06-07 | Regeneron Pharmaceuticals, Inc. | Method of treating an allergy with allergen-specific monoclonal antibodies |
| US20240228556A9 (en) * | 2021-02-23 | 2024-07-11 | Specialites Pet Food | Novel canine odorant binding proteins |
| CN117627400B (zh) * | 2024-01-26 | 2024-04-12 | 辽宁美耐金属建筑系统有限公司 | 一种金属屋面屋脊防坠落系统及防坠方法 |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0044532B1 (fr) | 1980-07-18 | 1986-04-23 | E.I. Du Pont De Nemours And Company | Monothioglycérol comme protecteur du groupe thiol dans des produits lyophilisés |
| US4442212A (en) * | 1980-11-10 | 1984-04-10 | E. I. Du Pont De Nemours & Company | Monothioglycerol as thiol-protector in lyophilized materials |
| US4855407A (en) | 1985-04-11 | 1989-08-08 | Alpha-1 Biomedicals, Inc. | Solid phase process for synthesizing peptides |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5547669A (en) * | 1989-11-03 | 1996-08-20 | Immulogic Pharma Corp | Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I |
| US6019972A (en) * | 1989-11-03 | 2000-02-01 | Immulogic Pharmaceutical Corporation | Peptides of human T cell reactive feline protein (TRFP) |
| DE69033949T2 (de) | 1989-11-03 | 2002-11-14 | Immulogic Pharmaceutical Corp., Cambridge | Aus hausstaub isoliertes t-zellreaktives katzenprotein, und dessen verwendungen |
| US5593698A (en) | 1990-10-31 | 1997-01-14 | Autoimmune, Inc. | Suppression of proliferative response and induction of tolerance with polymorphic class II MHC allopeptides |
| US6982326B1 (en) * | 1991-07-12 | 2006-01-03 | Immulogic Pharmaceutical Corporation | Allergenic proteins and peptides from Japanese cedar pollen |
| US6555116B1 (en) | 1991-10-12 | 2003-04-29 | Regents Of The University Of California | Alleviation of the allergenic potential of airborne and contact allergens by thioredoxin |
| WO1994024281A1 (fr) | 1993-04-14 | 1994-10-27 | Immulogic Pharmaceutical Corporation | Epitopes de lymphocytes t des principaux allergenes de dermatophagoides (acariens detriticoles) |
| EP0623168B1 (fr) | 1991-10-16 | 2009-09-30 | Merck Patent GmbH | Epitopes de lymphocytes t des allergenes principaux des dermatophagoides (acariens de la poussiere) |
| JPH07507924A (ja) | 1992-04-09 | 1995-09-07 | イミュロジック ファーマスーティカル コーポレイション | アンブロシア・アルテミシフォリア由来の主要アレルゲンのｔ細胞エピトープ |
| US5480972A (en) | 1992-10-30 | 1996-01-02 | The University Of Melbourne | Allergenic proteins from Johnson grass pollen |
| ES2260756T3 (es) | 1992-12-31 | 2006-11-01 | Heska Corporation | Proteina y peptidos alergenicos de caspa de perro y sus usos. |
| US5697103A (en) | 1993-01-11 | 1997-12-16 | Personal Expression I, Inc. | Therapeutic glove |
| JPH08509966A (ja) | 1993-03-12 | 1996-10-22 | イミュロジック ファーマスーティカル コーポレイション | ライグラス花粉アレルゲンのｔ細胞エピトープ |
| WO1994027634A1 (fr) | 1993-06-02 | 1994-12-08 | Institute For Child Health Research | Peptides caches permettant d'induire une tolerance immunologique |
| NZ271818A (en) | 1993-08-13 | 1997-11-24 | Immulogic Pharma Corp | T cell epitopes of ryegrass pollen antigen |
| JPH07215996A (ja) | 1994-01-31 | 1995-08-15 | Torii Yakuhin Kk | ダニアレルゲンのｂ細胞エピトープ |
| US5820862A (en) * | 1994-04-14 | 1998-10-13 | Immulogic Pharmaceutical Corporation | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| ATE359296T1 (de) | 1994-04-14 | 2007-05-15 | Merck Patent Gmbh | Pharmazeutische peptide formulierungen zur behandlung von staubmilben allergie |
| JPH10505356A (ja) | 1994-09-02 | 1998-05-26 | イミユロジク・フアーマシユーチカル・コーポレーシヨン | ヒトへの投与のための組成物および方法、抗原特異的免疫応答のダウンレギュレーションを行うことが可能なペプチド |
| IL115744A (en) | 1994-10-27 | 2000-07-16 | Akzo Nobel Nv | Peptides comprising a subsequence of human cartilage glycoprotein - 39 |
| DE19508192A1 (de) * | 1995-03-09 | 1996-09-12 | Behringwerke Ag | Stabile Transglutaminasepräparate und Verfahren zu ihrer Herstellung |
| JP4340329B2 (ja) | 1996-03-21 | 2009-10-07 | サーカッシア リミテッド | 潜在ペプチドならびにそれらの同定方法 |
| US6238888B1 (en) | 1997-12-22 | 2001-05-29 | Human Genone Sciences, Inc. | Keratinocyte growth factor-2 formulations |
| CA2317724A1 (fr) | 1998-01-09 | 1999-07-15 | Circassia Limited | Procedes et compositions de desensibilisation |
| AU2001278637B2 (en) | 2000-08-21 | 2006-05-25 | Apitope Technology (Bristol) Limited | Peptide selection method |
| AU2001286996A1 (en) * | 2000-08-31 | 2002-03-13 | Chiron Corporation | Stabilized fgf formulations containing reducing agents |
| US7786257B2 (en) * | 2000-12-18 | 2010-08-31 | University Of Kansas | Signal-1/signal-2 bifunctional peptide inhibitors |
| FR2820425B1 (fr) | 2001-02-08 | 2004-01-02 | Commissariat Energie Atomique | Melange de peptides issus d'une proteine nef et leurs applications |
| AU2002305138A1 (en) | 2001-04-09 | 2002-10-21 | Mayo Foundation For Medical Education And Research | Methods and materials for cancer treatment |
| PT1450847E (pt) | 2001-11-13 | 2011-01-05 | Genentech Inc | Formulações de ligando de apo2/trail e suas utilizações |
| ES2316632T3 (es) | 2001-12-05 | 2009-04-16 | Circassia Limited | Metodos y sistemas inmunoterapeuticos. |
| AUPS148202A0 (en) | 2002-04-02 | 2002-05-09 | Monash University | Immunotherapeutic and immunoprophylactic reagents |
| CA2485217C (fr) | 2002-05-06 | 2012-05-01 | Thomas Jefferson University | Peptides lies a l'insuline ayant des effets sur la sante cerebrale |
| US20040071718A1 (en) * | 2002-09-18 | 2004-04-15 | Jaw-Ji Tsai | Local nasal immunotherapy for allergen-induced airway inflammation |
| CA2518187A1 (fr) | 2003-03-07 | 2004-09-16 | London Health Sciences Centre Reseach, Inc. | Peptides associes a des molecules hla-dr mhc de classe ii impliquees dans des maladies auto-immunes |
| US7923209B2 (en) * | 2003-03-14 | 2011-04-12 | Anergis, S.A. | Allergen peptide fragments and use thereof |
| EP1636261B1 (fr) | 2003-06-26 | 2007-08-01 | MERCK PATENT GmbH | Proteines de thrombopoietine a proprietes ameliorees |
| GB0315754D0 (en) | 2003-07-04 | 2003-08-13 | Univ Aberdeen | Pharmaceutical compositions |
| EP1685160A1 (fr) | 2003-11-10 | 2006-08-02 | Arriva-Prometic Inc. | Preparation seche de alpha 1-antitrypsine humaine obtenue par recombinaison |
| WO2005065706A1 (fr) | 2003-12-31 | 2005-07-21 | Orthologic Corp. | Composition pharmaceutique pour derives peptidiques de la thrombine |
| US20060029551A1 (en) | 2004-08-05 | 2006-02-09 | Kui Liu | Stable particle formulations of erythropoietin receptor agonists |
| WO2006075253A2 (fr) | 2005-01-11 | 2006-07-20 | Commissariat A L'energie Atomique | Peptides destines a desensibiliser des sujets allergiques au poil de chien ou aux squames, et compositions contenant ces peptides |
| AU2006210895A1 (en) | 2005-02-01 | 2006-08-10 | Attenuon, Llc | Compositions containing the anti-angiogenic PHSCN-peptide |
| FR2881746B1 (fr) | 2005-02-07 | 2007-04-13 | Centre Nat Rech Scient | Epitopes t cd4+des antigenes de latence de type i et ii du virus epstein-barr aptes a etre reconnus par la majorite des individus de la population caucasienne et leurs applications |
| WO2006127910A2 (fr) | 2005-05-25 | 2006-11-30 | Neose Technologies, Inc. | Formulations d'erythropoietine glycopegylees |
| EP1956985A2 (fr) * | 2005-11-23 | 2008-08-20 | Universität Zürich | Traitement d'une allergie par administration épicutanée d'un allergène |
| CN1840708A (zh) * | 2006-01-23 | 2006-10-04 | 南开大学 | 用于治疗免疫耐受相关疾病的基因的筛选和鉴定方法 |
| GB0609121D0 (en) | 2006-05-09 | 2006-06-21 | Univ Birmingham | Peptide Therapy |
| GB0701048D0 (en) | 2007-01-18 | 2007-02-28 | Univ Aberdeen | A composition |
| EP1958645A1 (fr) | 2007-02-13 | 2008-08-20 | Biomay AG | Peptides dérivés du allergène majeur de l'ambrosie (Ambrosia artemisiifolia) et leur utilisation |
| US8148105B2 (en) | 2007-03-16 | 2012-04-03 | The Board Of Trustees Of The Leland Stanford Junior University | Scaleable manufacturing process for cysteine endoprotease B, isoform 2 |
| GB0710529D0 (en) * | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
| AU2008288283B2 (en) | 2007-08-15 | 2013-01-31 | Circassia Limited | Peptides for desensibilization against allergens |
-
2007
- 2007-06-01 GB GBGB0710529.9A patent/GB0710529D0/en not_active Ceased
-
2008
- 2008-05-30 JP JP2010509893A patent/JP5366936B2/ja not_active Expired - Fee Related
- 2008-05-30 CA CA2689260A patent/CA2689260C/fr active Active
- 2008-05-30 CN CN201410081704.6A patent/CN104027801A/zh active Pending
- 2008-05-30 AT AT08762207T patent/ATE481984T1/de active
- 2008-05-30 PT PT08762207T patent/PT2079481E/pt unknown
- 2008-05-30 ES ES08762207.2T patent/ES2353360T5/es active Active
- 2008-05-30 ES ES11182398.5T patent/ES2573700T3/es active Active
- 2008-05-30 DK DK08762207.2T patent/DK2079481T4/en active
- 2008-05-30 SI SI200830096T patent/SI2079481T1/sl unknown
- 2008-05-30 WO PCT/GB2008/001833 patent/WO2008146003A1/fr active Application Filing
- 2008-05-30 EP EP08762207.2A patent/EP2079481B2/fr not_active Not-in-force
- 2008-05-30 DE DE602008002693T patent/DE602008002693D1/de active Active
- 2008-05-30 PL PL08762207T patent/PL2079481T3/pl unknown
- 2008-05-30 EP EP10006684A patent/EP2380591A3/fr not_active Withdrawn
- 2008-05-30 AU AU2008256524A patent/AU2008256524B2/en not_active Ceased
- 2008-05-30 CN CN200880101107.8A patent/CN101808660B/zh active Active
- 2008-05-30 WO PCT/GB2008/001827 patent/WO2008145998A1/fr active Application Filing
- 2008-05-30 EP EP11182398.5A patent/EP2428222B1/fr not_active Not-in-force
- 2008-05-30 US US12/602,313 patent/US8551492B2/en active Active
-
2009
- 2009-12-30 HK HK09112345.8A patent/HK1132935A1/xx not_active IP Right Cessation
-
2010
- 2010-11-24 HR HR20100644T patent/HRP20100644T1/hr unknown
- 2010-12-07 CY CY20101101126T patent/CY1110980T1/el unknown
-
2013
- 2013-07-19 JP JP2013150710A patent/JP5857002B2/ja not_active Expired - Fee Related
- 2013-08-22 US US13/973,117 patent/US9168295B2/en active Active
-
2015
- 2015-09-11 US US14/851,842 patent/US20160120965A1/en not_active Abandoned
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