HRP20100385T1 - Humanizirani anti-cmet antagonisti - Google Patents

Humanizirani anti-cmet antagonisti Download PDF

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Publication number
HRP20100385T1
HRP20100385T1 HR20100385T HRP20100385T HRP20100385T1 HR P20100385 T1 HRP20100385 T1 HR P20100385T1 HR 20100385 T HR20100385 T HR 20100385T HR P20100385 T HRP20100385 T HR P20100385T HR P20100385 T1 HRP20100385 T1 HR P20100385T1
Authority
HR
Croatia
Prior art keywords
antibody
antibody according
seq
sequence
cancer
Prior art date
Application number
HR20100385T
Other languages
English (en)
Croatian (hr)
Inventor
S. Dennis Mark
Billeci Karen
Young Judy
Zheng Zhong
Original Assignee
Genentech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech filed Critical Genentech
Publication of HRP20100385T1 publication Critical patent/HRP20100385T1/hr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
HR20100385T 2004-08-05 2010-07-13 Humanizirani anti-cmet antagonisti HRP20100385T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59899104P 2004-08-05 2004-08-05
PCT/US2005/027626 WO2006015371A2 (en) 2004-08-05 2005-08-04 Humanized anti-cmet antagonists

Publications (1)

Publication Number Publication Date
HRP20100385T1 true HRP20100385T1 (hr) 2010-10-31

Family

ID=35787927

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100385T HRP20100385T1 (hr) 2004-08-05 2010-07-13 Humanizirani anti-cmet antagonisti

Country Status (27)

Country Link
US (6) US7476724B2 (el)
EP (1) EP1773885B1 (el)
JP (2) JP5068651B2 (el)
KR (1) KR101397851B1 (el)
CN (3) CN104804095A (el)
AT (1) ATE465181T1 (el)
AU (1) AU2005267720B2 (el)
BR (1) BRPI0513666A (el)
CA (1) CA2575402A1 (el)
CY (1) CY1111622T1 (el)
DE (1) DE602005020799D1 (el)
DK (1) DK1773885T3 (el)
ES (1) ES2344793T3 (el)
HK (2) HK1100779A1 (el)
HR (1) HRP20100385T1 (el)
IL (3) IL180588A (el)
ME (1) ME01803B (el)
MX (1) MX2007001470A (el)
NO (1) NO20071188L (el)
NZ (1) NZ552485A (el)
PL (1) PL1773885T3 (el)
PT (1) PT1773885E (el)
RS (1) RS51326B (el)
RU (1) RU2398777C2 (el)
SI (1) SI1773885T1 (el)
WO (1) WO2006015371A2 (el)
ZA (1) ZA200701656B (el)

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