HRP20090167T1 - New benzimidazole derivatives - Google Patents
New benzimidazole derivativesInfo
- Publication number
- HRP20090167T1 HRP20090167T1 HR20090167T HRP20090167T HRP20090167T1 HR P20090167 T1 HRP20090167 T1 HR P20090167T1 HR 20090167 T HR20090167 T HR 20090167T HR P20090167 T HRP20090167 T HR P20090167T HR P20090167 T1 HRP20090167 T1 HR P20090167T1
- Authority
- HR
- Croatia
- Prior art keywords
- 6alkyl
- nr6r7
- r6oc0
- r6co
- 6haloalkyl
- Prior art date
Links
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 abstract 3
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 2
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
- -1 NR6R7 Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/16—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/56—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in ortho-position
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
- C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0301446A SE0301446D0 (sv) | 2003-05-16 | 2003-05-16 | New Compounds |
SE0400043A SE0400043D0 (sv) | 2003-05-16 | 2004-01-12 | New compounds |
PCT/SE2004/000738 WO2004100865A2 (fr) | 2003-05-16 | 2004-05-13 | Nouveaux derives de benzimidazole |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20090167T1 true HRP20090167T1 (en) | 2009-05-31 |
Family
ID=33455734
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20090167T HRP20090167T1 (en) | 2003-05-16 | 2009-03-19 | New benzimidazole derivatives |
Country Status (33)
Country | Link |
---|---|
US (1) | US7645784B2 (fr) |
EP (2) | EP2042490A3 (fr) |
JP (1) | JP4762903B2 (fr) |
KR (1) | KR101110404B1 (fr) |
CN (2) | CN101328150A (fr) |
AR (1) | AR044342A1 (fr) |
AT (1) | ATE421506T1 (fr) |
AU (2) | AU2004238177B2 (fr) |
BR (1) | BRPI0410316A (fr) |
CA (1) | CA2525628C (fr) |
CO (1) | CO5631436A2 (fr) |
CY (1) | CY1108894T1 (fr) |
DE (1) | DE602004019208D1 (fr) |
DK (1) | DK1626964T3 (fr) |
ES (1) | ES2319529T3 (fr) |
HK (1) | HK1085735A1 (fr) |
HR (1) | HRP20090167T1 (fr) |
IL (1) | IL199668A0 (fr) |
IS (1) | IS2656B (fr) |
MX (1) | MXPA05012247A (fr) |
MY (1) | MY140235A (fr) |
NO (1) | NO20055977L (fr) |
NZ (1) | NZ543075A (fr) |
PL (1) | PL1626964T3 (fr) |
PT (1) | PT1626964E (fr) |
RU (1) | RU2337098C2 (fr) |
SE (2) | SE0301446D0 (fr) |
SG (2) | SG164283A1 (fr) |
SI (1) | SI1626964T1 (fr) |
TW (1) | TWI333950B (fr) |
UA (1) | UA85842C2 (fr) |
WO (1) | WO2004100865A2 (fr) |
ZA (1) | ZA200509241B (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2377484T3 (es) * | 2003-09-03 | 2012-03-28 | Pfizer, Inc. | Compuestos de bencimidazolona que tiene actividad agonista del receptor 5-HT |
SE0402284D0 (sv) * | 2004-09-21 | 2004-09-21 | Astrazeneca Ab | New heterocyclic amides |
CA2581335A1 (fr) * | 2004-09-21 | 2006-03-30 | Athersys, Inc. | Acides benzimidazole acetiques presentant un antagonisme du recepteur crth2 et utilisations associees |
TWI401254B (zh) * | 2005-05-09 | 2013-07-11 | Hydra Biosciences Inc | 用於調節trpv3功能之化合物 |
US8916550B2 (en) | 2005-05-09 | 2014-12-23 | Hydra Biosciences, Inc. | Compounds for modulating TRPV3 function |
KR20110093948A (ko) | 2005-07-22 | 2011-08-18 | 모찌다 세이야쿠 가부시끼가이샤 | 신규 헤테로시클리덴 아세트아미드 유도체 |
RU2451014C2 (ru) * | 2005-07-22 | 2012-05-20 | Мотида Фармасьютикал Ко., Лтд. | Новое производное гетероциклиден ацетамида |
AU2006311036A1 (en) * | 2005-11-08 | 2007-05-18 | Msd Oss B.V. | 2-(benzimidazol-1-yl)-N-(4-phenylthiazol-2-yl) acetamide derivatives useful in treatment of TRPV1 related disorders |
WO2007054480A1 (fr) | 2005-11-08 | 2007-05-18 | N.V. Organon | Derives bisarylique de 2-(benzimidazol-1-yl)-acetamide et leur utilisation comme inhibiteurs du recepteur trpv1 |
UY30048A1 (es) * | 2005-12-23 | 2007-07-31 | Astrazeneca Ab | Derivados sustituidos de la n,2-(1h-benzimidazol-1-il) acetamida, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones |
WO2007091946A1 (fr) * | 2006-02-07 | 2007-08-16 | Astrazeneca Ab | Utilisation de spiro[imidazolidine-4,3'-indole]2,2',5'(1h)triones pour le traitement de troubles associes au recepteur 1 de vanilloide |
TW200801011A (en) | 2006-02-07 | 2008-01-01 | Astrazeneca Ab | New compounds II |
JP2009526044A (ja) * | 2006-02-07 | 2009-07-16 | アストラゼネカ・アクチエボラーグ | 新規な化合物i |
TWI433839B (zh) | 2006-08-11 | 2014-04-11 | Neomed Inst | 新穎的苯并咪唑衍生物290 |
EP2099444A4 (fr) | 2006-12-14 | 2012-11-07 | Nps Pharma Inc | Utilisation de dérivés de la d-sérine pour le traitement de troubles de l'anxiété |
PE20081692A1 (es) * | 2007-01-24 | 2008-12-18 | Mochida Pharm Co Ltd | Nuevo derivado de heterocicliden acetamida |
DE102007018151A1 (de) | 2007-04-16 | 2008-10-23 | Günenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
CA2683461A1 (fr) * | 2007-04-16 | 2008-10-23 | Gruenenthal Gmbh | Nouveaux ligands du recepteur vanilloide et leur utilisation pour la fabrication de medicaments |
DE102007018149A1 (de) | 2007-04-16 | 2008-10-23 | Grünenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
US10179761B2 (en) | 2014-06-16 | 2019-01-15 | Universite De Lille 2 Droit Et Sante | Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases |
JP2018052817A (ja) * | 2015-01-21 | 2018-04-05 | 大日本住友製薬株式会社 | 新規ベンズイミダゾール誘導体およびその医薬用途 |
WO2018051252A2 (fr) * | 2016-09-15 | 2018-03-22 | Insecticides (India) Limited | Nouveau composé amide, son procédé de production et miticide |
WO2020142842A1 (fr) * | 2019-01-08 | 2020-07-16 | Neomed Institute - Institut Neomed | Formes cristallines de (s)-2-(7-cyano-1h-benzimidazol-1 yl)- n-{1-[4-(1-cyano-1-méthyléthyl)phényl]éthyl}acétamide |
WO2022211518A1 (fr) * | 2021-04-02 | 2022-10-06 | 파렌키마바이오텍 주식회사 | Nouveau composé et son utilisation dans le traitement du psoriasis, de l'asthme ou du lupus érythémateux disséminé |
DE102022104759A1 (de) | 2022-02-28 | 2023-08-31 | SCi Kontor GmbH | Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen |
Family Cites Families (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1186504A (en) * | 1966-10-15 | 1970-04-02 | Fisons Pest Control Ltd | Substituted Heterocyclic Compounds |
IT1036004B (it) | 1968-05-21 | 1979-10-30 | Abc Ist Biolog Chem Spa | Acidt 3 indolil adetoidrossamici |
BE793718A (fr) | 1972-01-07 | 1973-07-05 | Merck & Co Inc | Aminobenzimidazoles |
DE3347290A1 (de) * | 1983-12-28 | 1985-07-11 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue 2-phenyl-imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
US4738981A (en) | 1984-11-13 | 1988-04-19 | Warner-Lambert | Substituted trans-1,2-diaminocyclohexyl amide compounds |
JPH06759B2 (ja) * | 1989-09-22 | 1994-01-05 | ファイザー製薬株式会社 | 新規なベンゾイミダゾール化合物 |
DE4309969A1 (de) * | 1993-03-26 | 1994-09-29 | Bayer Ag | Substituierte heteroanellierte Imidazole |
DE4491980B4 (de) * | 1993-03-30 | 2006-05-11 | Dainippon Ink And Chemicals, Inc. | Härtbare Harzmasse, ihre Verwendung sowie Anstrichmittel |
US5403851A (en) | 1994-04-05 | 1995-04-04 | Interneuron Pharmaceuticals, Inc. | Substituted tryptamines, phenalkylamines and related compounds |
HUT78019A (hu) * | 1995-03-31 | 1999-05-28 | András Horváth | Eljárás szubsztituált nitrogéntartalmú, heterociklusos vegyületek szintézisére |
WO1997012613A1 (fr) * | 1995-10-05 | 1997-04-10 | Warner-Lambert Company | Procede de traitement et de prevention des inflammations et de l'atherosclerose |
EA002357B1 (ru) | 1995-12-28 | 2002-04-25 | Фудзисава Фармасьютикал Ко., Лтд. | Производные бензимидазола |
CZ295468B6 (cs) | 1996-04-12 | 2005-08-17 | Warner-Lambert Company | Polycyklické sloučeniny |
GB9713484D0 (en) | 1997-06-27 | 1997-09-03 | Smithkline Beecham Plc | Neuroprotective vanilloid compounds |
JP2000095767A (ja) | 1998-09-28 | 2000-04-04 | Takeda Chem Ind Ltd | 性腺刺激ホルモン放出ホルモン拮抗剤 |
KR20020060160A (ko) | 1999-08-12 | 2002-07-16 | 파마시아 이탈리아 에스.피.에이. | 3(5)-아미노-피라졸 유도체, 이의 제조 방법 및항종양제로서의 이의 용도 |
US6534651B2 (en) * | 2000-04-06 | 2003-03-18 | Inotek Pharmaceuticals Corp. | 7-Substituted isoindolinone inhibitors of inflammation and reperfusion injury and methods of use thereof |
WO2001085722A1 (fr) * | 2000-05-05 | 2001-11-15 | Cor Therapeutics, Inc. | Sulfonamides heterobicycliques et utilisation de celles-ci comme inhibiteurs de recepteur adp des plaquettes |
US6943174B2 (en) | 2000-06-14 | 2005-09-13 | Warner-Lambert Company | 6,5-Fused bicyclic heterocycles |
US6448281B1 (en) * | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
CA2420042A1 (fr) | 2000-08-22 | 2003-02-18 | Mikio Ogawa | Derives d'acide carboxylique, procede de production de ceux-ci et medicaments contenant ceux-ci comme principe actif |
GB0031315D0 (en) * | 2000-12-21 | 2001-02-07 | Glaxo Group Ltd | Indole derivatives |
ITTO20010110A1 (it) | 2001-02-08 | 2002-08-08 | Rotta Research Lab | Nuovi derivati benzamidinici dotati di attivita' anti-infiammatoria ed immunosoppressiva. |
GB0105895D0 (en) | 2001-03-09 | 2001-04-25 | Smithkline Beecham Plc | Novel compounds |
SE0101387D0 (sv) * | 2001-04-20 | 2001-04-20 | Astrazeneca Ab | Novel compounds |
GB0110901D0 (en) | 2001-05-02 | 2001-06-27 | Smithkline Beecham Plc | Novel Compounds |
EA008476B1 (ru) | 2001-06-11 | 2007-06-29 | Биовитрум Аб | Замещенные сульфонамиды, способ их получения и их применение в качестве лечебного средства для лечения расстройств цнс, ожирения и диабета типа ii |
TWI239942B (en) * | 2001-06-11 | 2005-09-21 | Dainippon Pharmaceutical Co | N-arylphenylacetamide derivative and pharmaceutical composition containing the same |
WO2003014064A1 (fr) | 2001-07-31 | 2003-02-20 | Bayer Healthcare Ag | Derives amines |
PE20030417A1 (es) | 2001-09-13 | 2003-08-06 | Smithkline Beecham Plc | Derivados de urea como antagonistas del receptor vainilloide |
TWI231757B (en) | 2001-09-21 | 2005-05-01 | Solvay Pharm Bv | 1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity |
CA2468544A1 (fr) | 2001-12-10 | 2003-06-19 | Amgen Inc. | Ligands de recepteur vanilloide et utilisation de ceux-ci dans des traitements |
GB0130550D0 (en) | 2001-12-20 | 2002-02-06 | Smithkline Beecham Plc | Novel compounds |
EP2033953A1 (fr) | 2002-02-15 | 2009-03-11 | Glaxo Group Limited | Modulateurs des récepteurs vanilloides |
US20030158188A1 (en) * | 2002-02-20 | 2003-08-21 | Chih-Hung Lee | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
SG156524A1 (en) * | 2002-06-20 | 2009-11-26 | Biovitrum Ab Publ | New compounds useful for the treatment of obesity, type ii diabetes and cns disorders |
GB0221157D0 (en) | 2002-09-12 | 2002-10-23 | Glaxo Group Ltd | Novel treatment |
WO2004024710A1 (fr) | 2002-09-13 | 2004-03-25 | Glaxo Group Limited | Composes a base d'uree, actifs en tant qu'antagonistes du recepteur de la vanilloide et utilises pour traiter les douleurs |
US7582761B2 (en) * | 2002-10-17 | 2009-09-01 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
SE0301701D0 (sv) * | 2003-06-10 | 2003-06-10 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
ES2377484T3 (es) | 2003-09-03 | 2012-03-28 | Pfizer, Inc. | Compuestos de bencimidazolona que tiene actividad agonista del receptor 5-HT |
EP1736465A4 (fr) | 2004-03-31 | 2009-06-17 | Ajinomoto Kk | Dérivés d'aniline |
WO2006007851A2 (fr) | 2004-07-19 | 2006-01-26 | Novo Nordisk A/S | Inhibition de l'activite du recepteur de la capsaicine dans le traitement de l'obesite ou de maladies et de troubles associe(e)s a l'obesite |
SE0402284D0 (sv) | 2004-09-21 | 2004-09-21 | Astrazeneca Ab | New heterocyclic amides |
UY30048A1 (es) | 2005-12-23 | 2007-07-31 | Astrazeneca Ab | Derivados sustituidos de la n,2-(1h-benzimidazol-1-il) acetamida, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones |
TWI433839B (zh) | 2006-08-11 | 2014-04-11 | Neomed Inst | 新穎的苯并咪唑衍生物290 |
-
2003
- 2003-05-16 SE SE0301446A patent/SE0301446D0/xx unknown
-
2004
- 2004-01-12 SE SE0400043A patent/SE0400043D0/xx unknown
- 2004-05-10 TW TW093113091A patent/TWI333950B/zh not_active IP Right Cessation
- 2004-05-13 PT PT04732865T patent/PT1626964E/pt unknown
- 2004-05-13 SG SG200717748-8A patent/SG164283A1/en unknown
- 2004-05-13 SG SG200717747-0A patent/SG171471A1/en unknown
- 2004-05-13 AU AU2004238177A patent/AU2004238177B2/en not_active Ceased
- 2004-05-13 CN CNA2008101360511A patent/CN101328150A/zh active Pending
- 2004-05-13 JP JP2006532186A patent/JP4762903B2/ja not_active Expired - Fee Related
- 2004-05-13 US US10/556,229 patent/US7645784B2/en not_active Expired - Fee Related
- 2004-05-13 EP EP08171574A patent/EP2042490A3/fr not_active Withdrawn
- 2004-05-13 MX MXPA05012247A patent/MXPA05012247A/es active IP Right Grant
- 2004-05-13 UA UAA200510093A patent/UA85842C2/uk unknown
- 2004-05-13 DE DE602004019208T patent/DE602004019208D1/de not_active Expired - Lifetime
- 2004-05-13 PL PL04732865T patent/PL1626964T3/pl unknown
- 2004-05-13 EP EP04732865A patent/EP1626964B1/fr not_active Expired - Lifetime
- 2004-05-13 RU RU2005136529/04A patent/RU2337098C2/ru not_active IP Right Cessation
- 2004-05-13 KR KR1020057021744A patent/KR101110404B1/ko not_active IP Right Cessation
- 2004-05-13 DK DK04732865T patent/DK1626964T3/da active
- 2004-05-13 WO PCT/SE2004/000738 patent/WO2004100865A2/fr active Application Filing
- 2004-05-13 BR BRPI0410316-5A patent/BRPI0410316A/pt not_active IP Right Cessation
- 2004-05-13 AT AT04732865T patent/ATE421506T1/de active
- 2004-05-13 NZ NZ543075A patent/NZ543075A/en not_active IP Right Cessation
- 2004-05-13 ES ES04732865T patent/ES2319529T3/es not_active Expired - Lifetime
- 2004-05-13 CA CA2525628A patent/CA2525628C/fr not_active Expired - Fee Related
- 2004-05-13 SI SI200431067T patent/SI1626964T1/sl unknown
- 2004-05-13 CN CNB2004800126199A patent/CN100413849C/zh not_active Expired - Fee Related
- 2004-05-14 AR ARP040101658A patent/AR044342A1/es unknown
- 2004-05-14 MY MYPI20041802A patent/MY140235A/en unknown
-
2005
- 2005-11-10 CO CO05114671A patent/CO5631436A2/es not_active Application Discontinuation
- 2005-11-15 ZA ZA200509241A patent/ZA200509241B/en unknown
- 2005-12-14 IS IS8180A patent/IS2656B/is unknown
- 2005-12-15 NO NO20055977A patent/NO20055977L/no not_active Application Discontinuation
-
2006
- 2006-05-20 HK HK06105843.2A patent/HK1085735A1/xx not_active IP Right Cessation
-
2008
- 2008-07-24 AU AU2008203305A patent/AU2008203305A1/en not_active Abandoned
-
2009
- 2009-03-19 CY CY20091100309T patent/CY1108894T1/el unknown
- 2009-03-19 HR HR20090167T patent/HRP20090167T1/xx unknown
- 2009-07-02 IL IL199668A patent/IL199668A0/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HRP20090167T1 (en) | New benzimidazole derivatives | |
RS52099B (en) | SUBSTITUTED BENZIMIDAZOLES AS KINASE INHIBITORS | |
ATE455103T1 (de) | Als antikoagulationsmittel geeignete phenylglycinamid- und pyridylglycinamidderivate | |
RS52061B (en) | PIRAZOLYL-AMINOPYRIDINE DERIVATIVES USEFUL AS KINASE INHIBITORS | |
NO20054787D0 (no) | Indenderivater som farmasotiske midler | |
DK1263722T3 (da) | Farmaceutiske sammensætninger, som indeholder azetidinderivat, nye azetidinderivater og fremstilling deraf | |
ATE556058T1 (de) | 1-(2h)-isochinolonderivat | |
DE69809187T2 (de) | Metalloproteinase-Inhibitoren | |
EP1490371A4 (fr) | Composes tricycliques a base de thiopene et compositions pharmaceutiques renfermant lesdits composes | |
DE60107449D1 (de) | Substituierte aminopropoxyarylderivate als lxr agonisten | |
HRP20090162T1 (en) | Quinolinone-carboxamide compounds as 5-ht4 receptor agonists | |
DK0867436T3 (da) | N-arylpiperidinderivater og deres anvendelse som 5-HT1B-receptorligander | |
ATE481387T1 (de) | Pyridin-n-oxidverbindungen alsphosphodiesterase-4-inhibitoren | |
RS51193B (sr) | Hidantoinski derivati korisni kao inhibitori metaloproteinaza | |
DE69224115D1 (de) | Heteroaryl substituierte Hydroxylaminderivate als Lipoxygenase-Inhibitoren | |
DE60313350D1 (de) | Pyrimidin-2,4-dion-derivate als matrix-metalloproteinase-hemmer | |
NO20050871L (no) | 6-amino-1H-indazol- og 4-aminobenzofuranforbindelser som fosfodiesterase 4-inhibitorer | |
DE60027144D1 (de) | Hydroxamsäure-derivate | |
NO20052994L (no) | Nye fosforamidderivater. | |
DK0870763T3 (da) | Kondenserede piperidinderivater som inhibitorer for syntese af nitrogenmonoxid | |
AR058839A1 (es) | Derivados de piperidina, utiles para el tratamiento de enfermedades proliferativas | |
RS54061B1 (en) | QUINOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONCERNING THEM, AND THEIR APPLICATIONS | |
ATE348800T1 (de) | 4'-methansulfonylbiphenylderivate als hochselektive cyclooxygenase-2-inhibitoren | |
NO20023298D0 (no) | Nye imidazolderivater | |
DE60108209D1 (de) | Fungizide Phenylimidate-Derivate |