HRP20020605B1 - Method for producing 4-(heteroaryl-methyl)-halogen-1(2h)-hthalazinones - Google Patents

Method for producing 4-(heteroaryl-methyl)-halogen-1(2h)-hthalazinones

Info

Publication number
HRP20020605B1
HRP20020605B1 HR20020605A HRP20020605A HRP20020605B1 HR P20020605 B1 HRP20020605 B1 HR P20020605B1 HR 20020605 A HR20020605 A HR 20020605A HR P20020605 A HRP20020605 A HR P20020605A HR P20020605 B1 HRP20020605 B1 HR P20020605B1
Authority
HR
Croatia
Prior art keywords
heteroaryl
methyl
hthalazinones
halogen
producing
Prior art date
Application number
HR20020605A
Other languages
English (en)
Croatian (hr)
Inventor
Petrov Orlin
Heiner Thomas
Neh Harribert
Krger Martin
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of HRP20020605A2 publication Critical patent/HRP20020605A2/hr
Publication of HRP20020605B1 publication Critical patent/HRP20020605B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
HR20020605A 1999-12-23 2000-12-20 Method for producing 4-(heteroaryl-methyl)-halogen-1(2h)-hthalazinones HRP20020605B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19963607A DE19963607B4 (de) 1999-12-23 1999-12-23 Verfahren zur Herstellung von 4-(Heteroaryl-methyl) halogen-1(2H)-phthalazinonen
PCT/EP2000/013027 WO2001047912A1 (de) 1999-12-23 2000-12-20 Verfahren zur herstellung von 4-(heteroaryl-methyl)-halogen-1(2h)-phthalazinonen

Publications (2)

Publication Number Publication Date
HRP20020605A2 HRP20020605A2 (en) 2004-12-31
HRP20020605B1 true HRP20020605B1 (en) 2007-06-30

Family

ID=7934888

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20020605A HRP20020605B1 (en) 1999-12-23 2000-12-20 Method for producing 4-(heteroaryl-methyl)-halogen-1(2h)-hthalazinones

Country Status (31)

Country Link
US (1) US6891041B2 (https=)
EP (1) EP1242405B1 (https=)
JP (1) JP2003529555A (https=)
KR (1) KR100654265B1 (https=)
CN (1) CN1221545C (https=)
AT (1) ATE273972T1 (https=)
AU (1) AU772981B2 (https=)
BG (1) BG65387B1 (https=)
BR (1) BR0016634A (https=)
CA (1) CA2395407C (https=)
CZ (1) CZ20022146A3 (https=)
DE (2) DE19963607B4 (https=)
DK (1) DK1242405T3 (https=)
EE (1) EE04940B1 (https=)
ES (1) ES2223626T3 (https=)
HR (1) HRP20020605B1 (https=)
HU (1) HUP0300992A3 (https=)
IL (2) IL150017A0 (https=)
MX (1) MXPA02006224A (https=)
NO (1) NO321357B1 (https=)
NZ (1) NZ519285A (https=)
PL (1) PL200714B1 (https=)
PT (1) PT1242405E (https=)
RO (1) RO121211B1 (https=)
RS (1) RS50458B (https=)
RU (1) RU2250900C2 (https=)
SI (1) SI1242405T1 (https=)
SK (1) SK285522B6 (https=)
UA (1) UA72021C2 (https=)
WO (1) WO2001047912A1 (https=)
ZA (1) ZA200205853B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1296984B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4
US7151102B2 (en) * 2000-10-30 2006-12-19 Kudos Pharmaceuticals Limited Phthalazinone derivatives
GB0419072D0 (en) 2004-08-26 2004-09-29 Kudos Pharm Ltd Phthalazinone derivatives
UY30639A1 (es) * 2006-10-17 2008-05-31 Kudos Pharm Ltd Derivados sustituidos de 2h-ftalazin-1-ona, sus formas cristalinas, proceso de preparacion y aplicaciones
CA2702429A1 (en) * 2007-10-17 2009-04-23 Kudos Pharmaceuticals Limited Crystalline form l 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2h-phthalazin-1-one
ES2598178T5 (es) 2008-10-07 2023-12-26 Kudos Pharm Ltd Formulación farmacéutica 514
MX365950B (es) 2013-03-13 2019-06-19 Flatley Discovery Lab Llc Compuestos de piridazinona y metodos para el tratamiento de la fibrosis quistica.
BR112017011831A2 (pt) * 2015-03-19 2017-12-26 Clariant Int Ltd tensoativos de amido açúcar biodegradáveis para recuperação avançada de petróleo

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE567431A (https=) * 1957-05-07
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
EP0634404A1 (en) * 1993-07-13 1995-01-18 Rhone Poulenc Agriculture Ltd. Phtalazin derivatives and their use as pesticides
WO1996005176A1 (en) * 1994-08-09 1996-02-22 Eisai Co., Ltd. Fused pyridazine compound
RU2128175C1 (ru) * 1994-08-09 1999-03-27 Эйсай Ко., Лтд. Конденсированный пиридазин или его фармакологически приемлемая соль, средство, проявляющее ингибирующую активность в отношении циклической гмф- фосфодиэстеразы
JP3919835B2 (ja) * 1994-08-09 2007-05-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 縮合ピリダジン系化合物
DE69720515T2 (de) * 1996-12-18 2004-02-19 Neurogen Corp., Branford Isoquinolinamin und phtalazinamin derivate, die reagieren mit crf rezeptoren
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
IT1296984B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4
ITMI981671A1 (it) * 1998-07-21 2000-01-21 Zambon Spa Derivati ftalazinici inibitori della fosfodisterasi 4
ITMI981670A1 (it) * 1998-07-21 2000-01-21 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4
ITMI20000261A1 (it) * 2000-02-16 2001-08-16 Zambon Group Processo per la preparazione di piridiniliden-ftalidi

Also Published As

Publication number Publication date
PT1242405E (pt) 2004-11-30
HRP20020605A2 (en) 2004-12-31
PL200714B1 (pl) 2009-01-30
HK1055296A1 (en) 2004-01-02
ES2223626T3 (es) 2005-03-01
IL150017A (en) 2006-12-31
AU2012201A (en) 2001-07-09
US20040192695A1 (en) 2004-09-30
SK8922002A3 (en) 2002-11-06
JP2003529555A (ja) 2003-10-07
SK285522B6 (sk) 2007-03-01
DE50007520D1 (de) 2004-09-23
BR0016634A (pt) 2002-10-15
EE04940B1 (et) 2007-12-17
PL355525A1 (en) 2004-05-04
NZ519285A (en) 2004-12-24
SI1242405T1 (en) 2005-02-28
EP1242405A1 (de) 2002-09-25
US6891041B2 (en) 2005-05-10
RS50458B (sr) 2010-03-02
BG106843A (en) 2003-02-28
HUP0300992A2 (hu) 2003-08-28
DE19963607A1 (de) 2001-07-12
EP1242405B1 (de) 2004-08-18
DE19963607B4 (de) 2005-12-15
CA2395407A1 (en) 2001-07-05
ATE273972T1 (de) 2004-09-15
ZA200205853B (en) 2004-02-18
MXPA02006224A (es) 2002-12-05
NO321357B1 (no) 2006-05-02
RO121211B1 (ro) 2007-01-30
CA2395407C (en) 2009-04-28
KR100654265B1 (ko) 2006-12-07
AU772981B2 (en) 2004-05-13
WO2001047912A1 (de) 2001-07-05
CZ20022146A3 (cs) 2002-09-11
CN1221545C (zh) 2005-10-05
EE200200307A (et) 2003-06-16
CN1413203A (zh) 2003-04-23
RU2002119559A (ru) 2004-01-10
UA72021C2 (en) 2005-01-17
DK1242405T3 (da) 2004-11-01
NO20023014L (no) 2002-06-21
RU2250900C2 (ru) 2005-04-27
IL150017A0 (en) 2002-12-01
HUP0300992A3 (en) 2005-11-28
KR20020062363A (ko) 2002-07-25
BG65387B1 (bg) 2008-05-30
NO20023014D0 (no) 2002-06-21
YU47302A (sh) 2005-06-10

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Legal Events

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Payment date: 20081204

Year of fee payment: 9

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Effective date: 20091221