HN2011000372A - Derivados de ciclohexil-amida y su uso como antagonistas de los receptores de crf-1 - Google Patents
Derivados de ciclohexil-amida y su uso como antagonistas de los receptores de crf-1Info
- Publication number
- HN2011000372A HN2011000372A HN2011000372A HN2011000372A HN2011000372A HN 2011000372 A HN2011000372 A HN 2011000372A HN 2011000372 A HN2011000372 A HN 2011000372A HN 2011000372 A HN2011000372 A HN 2011000372A HN 2011000372 A HN2011000372 A HN 2011000372A
- Authority
- HN
- Honduras
- Prior art keywords
- ciclohexil
- crf
- receivers
- amida
- antagonist
- Prior art date
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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Abstract
SE DESCRIBEN DERIVADOS DE CICLOHEXIL-AMIDA UTILES COMO ANTAGONISTAS DE LOS RECEPTORES DEL FACTOR DE LIBERACION DE CORTICOTROPINA (CRF-1)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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EP08162006 | 2008-08-07 | ||
EP09150543 | 2009-01-14 |
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HN2011000372A true HN2011000372A (es) | 2013-05-20 |
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HN2011000372A HN2011000372A (es) | 2008-08-07 | 2011-02-07 | Derivados de ciclohexil-amida y su uso como antagonistas de los receptores de crf-1 |
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US (3) | US8273900B2 (es) |
EP (1) | EP2323970B1 (es) |
JP (1) | JP5527745B2 (es) |
KR (1) | KR101302796B1 (es) |
CN (1) | CN102143940B (es) |
AR (1) | AR072969A1 (es) |
AU (1) | AU2009279089B2 (es) |
BR (1) | BRPI0917574A2 (es) |
CA (1) | CA2732887A1 (es) |
CO (1) | CO6351776A2 (es) |
EA (1) | EA020921B1 (es) |
EC (1) | ECSP11010814A (es) |
ES (1) | ES2582576T3 (es) |
HN (1) | HN2011000372A (es) |
IL (1) | IL210834A0 (es) |
MA (1) | MA32534B1 (es) |
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MY (1) | MY151568A (es) |
PE (1) | PE20110237A1 (es) |
SV (1) | SV2011003832A (es) |
TN (1) | TN2011000040A1 (es) |
TW (1) | TW201011001A (es) |
UY (1) | UY32036A (es) |
WO (1) | WO2010015655A1 (es) |
ZA (1) | ZA201100513B (es) |
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US8273900B2 (en) * | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
AR080056A1 (es) * | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
JP5748777B2 (ja) * | 2010-02-02 | 2015-07-15 | ノバルティス アーゲー | Crf受容体アンタゴニストとしてのシクロヘキシルアミド誘導体 |
KR101955691B1 (ko) | 2010-03-30 | 2019-03-07 | 베르선 코포레이션 | 트롬빈 억제제로서의 다중치환된 방향족 화합물 |
CA2822442C (en) | 2010-12-22 | 2021-03-16 | The Salk Institute For Biological Studies | Cyclic crf antagonist peptides |
AR086554A1 (es) | 2011-05-27 | 2014-01-08 | Novartis Ag | Derivados de la piperidina 3-espirociclica como agonistas de receptores de la ghrelina |
EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
AU2013255458A1 (en) | 2012-05-03 | 2014-10-09 | Novartis Ag | L-malate salt of 2, 7 - diaza - spiro [4.5 ] dec- 7 - yle derivatives and crystalline forms thereof as ghrelin receptor agonists |
US9814723B2 (en) | 2013-02-23 | 2017-11-14 | Lixin Zhang | Compositions and methods for prophylaxis and therapy for Meniere's disease |
RU2019101889A (ru) | 2013-03-15 | 2019-03-28 | Версеон Корпорейшн | Полизамещенные ароматические соединения в качестве ингибиторов сериновых протеаз |
JP6479749B2 (ja) * | 2013-03-15 | 2019-03-06 | ヴァーセオン コーポレイション | トロンビン阻害剤としてのハロゲノピラゾール |
IL296683B2 (en) | 2014-01-21 | 2023-12-01 | Neurocrine Biosciences Inc | Preparations for the treatment of congenital adrenal hyperplasia |
CN106535884A (zh) | 2014-06-06 | 2017-03-22 | 弗雷克萨斯生物科学公司 | 免疫调节剂 |
WO2016044662A1 (en) | 2014-09-17 | 2016-03-24 | Verseon Corporation | Pyrazolyl-substituted pyridone compounds as serine protease inhibitors |
UY36390A (es) | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen |
EP3215141A4 (en) | 2014-11-05 | 2018-06-06 | Flexus Biosciences, Inc. | Immunoregulatory agents |
UY36391A (es) * | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido1), sus métodos de síntesis y composiciones farmacèuticas que las contienen |
EP3261639B1 (en) | 2015-02-27 | 2022-08-24 | Verseon International Corporation | Substituted pyrazole compounds as serine protease inhibitors |
KR20200035035A (ko) | 2017-07-31 | 2020-04-01 | 노파르티스 아게 | 코카인 사용 감소 또는 코카인 사용 재발 예방에 있어서 마보글루란트의 용도 |
BR112020011914A2 (pt) | 2017-12-13 | 2020-11-24 | Praxis Biotech LLC | inibidores de via de resposta de tensão integrada |
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