HK1210500A1 - 融合基因和以其作為標靶的藥物 - Google Patents
融合基因和以其作為標靶的藥物Info
- Publication number
- HK1210500A1 HK1210500A1 HK15111263.0A HK15111263A HK1210500A1 HK 1210500 A1 HK1210500 A1 HK 1210500A1 HK 15111263 A HK15111263 A HK 15111263A HK 1210500 A1 HK1210500 A1 HK 1210500A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- fgfr3
- fusion gene
- drug targeting
- pharmaceutical drug
- targeting same
- Prior art date
Links
- 101150025764 FGFR3 gene Proteins 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 230000004927 fusion Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000008685 targeting Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
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- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012214739 | 2012-09-27 | ||
JP2013149217 | 2013-07-18 | ||
PCT/JP2013/076200 WO2014051022A1 (ja) | 2012-09-27 | 2013-09-27 | Fgfr3融合遺伝子およびそれを標的とする医薬 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1210500A1 true HK1210500A1 (zh) | 2016-04-22 |
Family
ID=50388416
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18103128.9A HK1243718A1 (zh) | 2012-09-27 | 2015-11-16 | Fgfr3融合基因和以其作為標靶的藥物 |
HK15111263.0A HK1210500A1 (zh) | 2012-09-27 | 2015-11-16 | 融合基因和以其作為標靶的藥物 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18103128.9A HK1243718A1 (zh) | 2012-09-27 | 2015-11-16 | Fgfr3融合基因和以其作為標靶的藥物 |
Country Status (15)
Country | Link |
---|---|
US (2) | US10689705B2 (zh) |
EP (1) | EP2902489B9 (zh) |
JP (2) | JP6117222B2 (zh) |
KR (1) | KR101942148B1 (zh) |
CN (2) | CN107501413A (zh) |
AU (1) | AU2013320972B2 (zh) |
CA (1) | CA2886002C (zh) |
EA (1) | EA031631B1 (zh) |
ES (1) | ES2643571T3 (zh) |
HK (2) | HK1243718A1 (zh) |
MX (1) | MX369550B (zh) |
RU (1) | RU2673943C2 (zh) |
SG (1) | SG11201502455TA (zh) |
TW (1) | TWI606066B (zh) |
WO (1) | WO2014051022A1 (zh) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2702305T3 (es) | 2012-03-08 | 2019-02-28 | Astellas Pharma Inc | Nuevo producto de fusión de FGFR3 |
MX369550B (es) | 2012-09-27 | 2019-11-12 | Chugai Pharmaceutical Co Ltd | Gen de fusion del receptor de factor de crecimiento de fibroblastos 3 (fgfr3) y medicamentos farmaceutico para tratar el mismo. |
EP2914622B1 (en) * | 2012-11-05 | 2023-06-07 | Foundation Medicine, Inc. | Novel fusion molecules and uses thereof |
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- 2013-09-27 SG SG11201502455TA patent/SG11201502455TA/en unknown
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MX2015003744A (es) | 2015-06-24 |
US10689705B2 (en) | 2020-06-23 |
TW201418284A (zh) | 2014-05-16 |
CN104797710A (zh) | 2015-07-22 |
KR20150060875A (ko) | 2015-06-03 |
JP6117222B2 (ja) | 2017-04-19 |
SG11201502455TA (en) | 2015-05-28 |
CN107501413A (zh) | 2017-12-22 |
MX369550B (es) | 2019-11-12 |
HK1243718A1 (zh) | 2018-07-20 |
EA031631B1 (ru) | 2019-01-31 |
CA2886002C (en) | 2020-06-09 |
JP2015231377A (ja) | 2015-12-24 |
US20200385812A1 (en) | 2020-12-10 |
AU2013320972B2 (en) | 2018-08-30 |
CA2886002A1 (en) | 2014-04-03 |
ES2643571T3 (es) | 2017-11-23 |
US20150307945A1 (en) | 2015-10-29 |
EP2902489B1 (en) | 2017-09-13 |
JPWO2014051022A1 (ja) | 2016-08-22 |
KR101942148B1 (ko) | 2019-01-24 |
RU2015114616A (ru) | 2016-11-20 |
EP2902489A1 (en) | 2015-08-05 |
EP2902489B9 (en) | 2018-02-07 |
EP2902489A4 (en) | 2015-10-21 |
WO2014051022A1 (ja) | 2014-04-03 |
AU2013320972A1 (en) | 2015-04-16 |
RU2673943C2 (ru) | 2018-12-03 |
TWI606066B (zh) | 2017-11-21 |
EA201500334A1 (ru) | 2016-01-29 |
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