HK1208284A1 - 複雜生物樣品如血清的深度 質譜及其用途 - Google Patents

複雜生物樣品如血清的深度 質譜及其用途

Info

Publication number
HK1208284A1
HK1208284A1 HK15108852.3A HK15108852A HK1208284A1 HK 1208284 A1 HK1208284 A1 HK 1208284A1 HK 15108852 A HK15108852 A HK 15108852A HK 1208284 A1 HK1208284 A1 HK 1208284A1
Authority
HK
Hong Kong
Prior art keywords
maldi tof
serum
deep
mass spectrometry
biological samples
Prior art date
Application number
HK15108852.3A
Other languages
English (en)
Inventor
Roder Heinrich
Asmellash Senait
Allen Jenna
Tsypin Maxim
Original Assignee
Biodesix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biodesix Inc filed Critical Biodesix Inc
Publication of HK1208284A1 publication Critical patent/HK1208284A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/626—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode using heat to ionise a gas
    • G01N27/628—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode using heat to ionise a gas and a beam of energy, e.g. laser enhanced ionisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0004—Imaging particle spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
HK15108852.3A 2012-05-29 2015-09-10 複雜生物樣品如血清的深度 質譜及其用途 HK1208284A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261652394P 2012-05-29 2012-05-29
PCT/US2013/031998 WO2013180818A2 (en) 2012-05-29 2013-03-15 Deep-maldi tof mass spectrometry of complex biological samples, e.g., serum, and uses thereof

Publications (1)

Publication Number Publication Date
HK1208284A1 true HK1208284A1 (zh) 2016-02-26

Family

ID=48014370

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15108852.3A HK1208284A1 (zh) 2012-05-29 2015-09-10 複雜生物樣品如血清的深度 質譜及其用途

Country Status (10)

Country Link
US (2) US9279798B2 (zh)
EP (1) EP2856495A2 (zh)
JP (1) JP2015518167A (zh)
KR (1) KR20150015531A (zh)
CN (1) CN104380430A (zh)
AU (1) AU2013267976B2 (zh)
CA (1) CA2874989A1 (zh)
HK (1) HK1208284A1 (zh)
TW (1) TW201348699A (zh)
WO (1) WO2013180818A2 (zh)

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Also Published As

Publication number Publication date
EP2856495A2 (en) 2015-04-08
JP2015518167A (ja) 2015-06-25
KR20150015531A (ko) 2015-02-10
CN104380430A (zh) 2015-02-25
TW201348699A (zh) 2013-12-01
US9606101B2 (en) 2017-03-28
US20130320203A1 (en) 2013-12-05
US9279798B2 (en) 2016-03-08
US20160018410A1 (en) 2016-01-21
AU2013267976B2 (en) 2016-06-02
WO2013180818A2 (en) 2013-12-05
WO2013180818A3 (en) 2014-11-13
CA2874989A1 (en) 2013-12-05
AU2013267976A1 (en) 2015-01-22

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