HK1217971A1 - 用於核酸分析的方法、組合物和試劑盒 - Google Patents

用於核酸分析的方法、組合物和試劑盒

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Publication number
HK1217971A1
HK1217971A1 HK16105925.1A HK16105925A HK1217971A1 HK 1217971 A1 HK1217971 A1 HK 1217971A1 HK 16105925 A HK16105925 A HK 16105925A HK 1217971 A1 HK1217971 A1 HK 1217971A1
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HK
Hong Kong
Prior art keywords
kits
compositions
methods
nucleic acid
acid analysis
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HK16105925.1A
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English (en)
Inventor
So Austin
Lucero Michael
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Toma Biosciences Inc
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Publication of HK1217971A1 publication Critical patent/HK1217971A1/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK16105925.1A 2013-02-21 2016-05-24 用於核酸分析的方法、組合物和試劑盒 HK1217971A1 (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361767718P 2013-02-21 2013-02-21
US201361769683P 2013-02-26 2013-02-26
US201361777702P 2013-03-12 2013-03-12
US201361780578P 2013-03-13 2013-03-13
US201361824894P 2013-05-17 2013-05-17
US201361870634P 2013-08-27 2013-08-27
PCT/US2014/017832 WO2014130890A1 (en) 2013-02-21 2014-02-21 Methods, compositions, and kits for nucleic acid analysis

Publications (1)

Publication Number Publication Date
HK1217971A1 true HK1217971A1 (zh) 2017-01-27

Family

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Family Applications (1)

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HK16105925.1A HK1217971A1 (zh) 2013-02-21 2016-05-24 用於核酸分析的方法、組合物和試劑盒

Country Status (9)

Country Link
US (3) US20160186267A1 (zh)
EP (1) EP2959016A4 (zh)
JP (2) JP2016513959A (zh)
CN (1) CN105339507A (zh)
CA (1) CA2902207A1 (zh)
GB (1) GB2526736A (zh)
HK (1) HK1217971A1 (zh)
SG (1) SG11201506660RA (zh)
WO (1) WO2014130890A1 (zh)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8583380B2 (en) 2008-09-05 2013-11-12 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
CA2810931C (en) 2010-09-24 2018-04-17 The Board Of Trustees Of The Leland Stanford Junior University Direct capture, amplification and sequencing of target dna using immobilized primers
US11261494B2 (en) 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
US20150203589A1 (en) 2012-07-24 2015-07-23 The Trustees Of Columbia University In The City Of New York Fusion proteins and methods thereof
WO2015086604A1 (en) * 2013-12-11 2015-06-18 Qiagen Gmbh Nucleic acid detection and quantification
TWI609968B (zh) 2014-09-16 2018-01-01 麗寶生醫股份有限公司 癌症檢測套組
US10550435B2 (en) 2014-11-12 2020-02-04 Neogenomics Laboratories, Inc. Determining tumor load and biallelic mutation in patients with CALR mutation using peripheral blood plasma
EP3925979A3 (en) * 2014-12-23 2022-03-23 The Trustees of Columbia University in the City of New York Fgfr-tacc fusion proteins and methods thereof
KR20170125044A (ko) * 2015-02-10 2017-11-13 더 차이니즈 유니버시티 오브 홍콩 암 스크리닝 및 태아 분석을 위한 돌연변이 검출법
CN104630375B (zh) * 2015-02-16 2018-10-30 北京圣谷同创科技发展有限公司 癌症基因突变及基因扩增检测
US20180142296A1 (en) * 2015-04-30 2018-05-24 Medical College Of Wisconsin, Inc. Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing cell-free dna
US10344336B2 (en) 2015-06-09 2019-07-09 Life Technologies Corporation Methods, systems, compositions, kits, apparatus and computer-readable media for molecular tagging
DK3325664T3 (da) 2015-07-23 2022-03-07 Univ Hong Kong Chinese Analyse af fragmenteringsmønstre for cellefrit DNA
CA2994601C (en) 2015-08-06 2020-08-25 F. Hoffmann-La Roche Ag Target enrichment by single probe primer extension
EP3423488A4 (en) * 2016-02-29 2019-11-06 Foundation Medicine, Inc. METHOD FOR THE TREATMENT OF CANCER
CN105821481B (zh) * 2016-04-28 2019-03-19 元码基因科技(苏州)有限公司 一种游离dna文库构建方法以及游离dna中低频突变的检测方法
CN105755153B (zh) * 2016-05-09 2019-08-23 厦门稀土材料研究所 Pcdh18基因在制备结直肠癌诊断试剂盒中的应用及试剂盒
EP3464629B1 (en) 2016-06-01 2021-09-08 F. Hoffmann-La Roche AG Immuno-pete
SG10201700260XA (en) * 2016-06-10 2018-01-30 Star Array Pte Ltd Rapid thermal cycling for sample analyses and processing
CN106283199B (zh) * 2016-08-27 2018-06-19 大连晶泰生物技术有限公司 检测肿瘤相关的50个热点突变基因的捕获文库和试剂盒
WO2018053362A1 (en) 2016-09-15 2018-03-22 ArcherDX, Inc. Methods of nucleic acid sample preparation
EP4198140B1 (en) * 2016-11-02 2024-09-04 ArcherDX, LLC Methods of nucleic acid sample preparation for immune repertoire sequencing
CN106755322A (zh) * 2016-11-25 2017-05-31 苏州首度基因科技有限责任公司 一种预测肺癌转移的试剂盒及其使用方法
CN106636366A (zh) * 2016-11-25 2017-05-10 苏州首度基因科技有限责任公司 预测胃癌转移的基因检测试剂盒及其使用方法
CN106701920A (zh) * 2016-11-25 2017-05-24 苏州首度基因科技有限责任公司 一种预测结直肠癌肝转移的试剂盒和使用方法
CN106755350A (zh) * 2016-12-02 2017-05-31 苏州首度基因科技有限责任公司 cfDNA文库qPCR定量标准品的制备方法
CN107312826A (zh) * 2016-12-22 2017-11-03 华东医药(杭州)基因科技有限公司 一种基于扩增矫正的数字pcr检测方法
CA3048859A1 (en) 2016-12-28 2018-07-05 Quest Diagnostics Investments Llc Compositions and methods for detecting circulating tumor dna
CA3051509A1 (en) 2017-01-25 2018-08-02 The Chinese University Of Hong Kong Diagnostic applications using nucleic acid fragments
WO2018162538A1 (en) 2017-03-08 2018-09-13 F. Hoffmann-La Roche Ag Primer extension target enrichment and improvements thereto including simultaneous enrichment of dna and rna
HUE049979T2 (hu) 2017-03-20 2020-11-30 Forma Therapeutics Inc Pirrolopirrol készítmények piruvát-kináz (PKR) aktivátorokként
WO2018191563A1 (en) 2017-04-12 2018-10-18 Karius, Inc. Sample preparation methods, systems and compositions
CN110770354B (zh) * 2017-04-19 2024-03-19 鹍远基因公司 用于文库构建和序列分析的组合物和方法
CN107090503B (zh) * 2017-04-27 2020-06-19 元码基因科技(北京)股份有限公司 探针组合物、基因捕获芯片、试剂盒及其应用
CA3067171A1 (en) * 2017-06-21 2018-12-27 Base4 Innovation Limited Method for investigating molecules such as nucleic acids
DK3649260T3 (en) * 2017-07-07 2022-08-08 Nipd Genetics Public Company Ltd Target-beriget multiplekset parallel analyse til vurdering af tumorbiomarkører
CN111212918A (zh) * 2017-09-15 2020-05-29 临床基因组学私人有限公司 甲基化分析方法
CN109504747A (zh) * 2017-09-15 2019-03-22 益善生物技术股份有限公司 基于Taqman-MGB探针的人UGT1A1基因多态性检测试剂盒
CN108148910A (zh) * 2017-12-18 2018-06-12 广东省人民医院(广东省医学科学院) 一种肺癌相关的285基因靶向捕获测序试剂盒及其应用
AU2019249422A1 (en) 2018-04-02 2020-10-15 Grail, Llc Methylation markers and targeted methylation probe panels
CN112352057A (zh) * 2018-04-12 2021-02-09 鹍远基因公司 用于癌症或肿瘤形成评估的组合物和方法
CN108949978B (zh) * 2018-07-10 2021-10-22 昆明理工大学 一组同时检测ercc基因多态性的引物及其应用
CN108676890B (zh) * 2018-07-12 2022-01-28 吉林大学 一种女性乳腺恶性肿瘤易感性预测试剂盒及系统
CN113226356A (zh) 2018-09-19 2021-08-06 福马治疗股份有限公司 活化丙酮酸激酶r
BR112021005188A2 (pt) 2018-09-19 2021-06-08 Forma Therapeutics, Inc. tratamento de anemia falciforme com um composto de ativação de piruvato cinase r
CA3111887A1 (en) 2018-09-27 2020-04-02 Grail, Inc. Methylation markers and targeted methylation probe panel
TW202035699A (zh) * 2018-10-09 2020-10-01 中央研究院 用於檢測樣本中的核酸的數位聚合酶連鎖反應方法
CN111118181B (zh) * 2018-10-31 2023-05-12 华东师范大学 一种细菌的检测方法
CN109337976A (zh) * 2018-12-24 2019-02-15 中国医学科学院北京协和医院 用于检测pik3cd基因e1021k位点突变的探针和引物组合及试剂盒
CN109837344B (zh) * 2019-03-04 2022-12-27 天津医科大学 一种甲基化的EphA7核苷酸片段及其检测方法和应用
WO2020227016A1 (en) * 2019-05-03 2020-11-12 Meso Scale Technologies, Llc. Kits for detecting one or more target nucleic acid analytes in a sample and methods of making and using the same
CN110592215A (zh) * 2019-09-27 2019-12-20 迈克生物股份有限公司 检测核酸序列的组合物及检测方法
CN111154872A (zh) * 2019-12-31 2020-05-15 浙江大学 用于检测肺癌驱动性基因突变的探针及试剂盒
CA3167725A1 (en) 2020-01-13 2021-07-22 Fluent Biosciences Inc. Single cell sequencing
CN111004843B (zh) * 2020-02-22 2022-08-16 黄志清 基于单链dna肽连接酶的jak1基因特定突变检测试剂盒及方法
CN110951850B (zh) * 2020-02-22 2022-08-16 福建晨欣科生物科技有限公司 一种jak2基因特定突变检测试剂盒及其检测方法
CN110964834B (zh) * 2020-02-22 2022-08-16 黄志清 一种jak1基因特定突变检测试剂盒及其检测方法
CN111088363B (zh) * 2020-02-22 2022-08-16 黄志清 基于双链dna肽连接酶的jak1基因特定突变检测试剂盒及方法
CN111004842B (zh) * 2020-02-22 2022-08-16 黄志清 基于单链rna肽连接酶的jak2基因特定突变检测试剂盒及方法
WO2021188500A1 (en) 2020-03-16 2021-09-23 Fluent Biosciences Inc. Multi-omic analysis in monodisperse droplets
CN113667747A (zh) * 2020-05-14 2021-11-19 长庚大学 治疗口腔癌的方法
CN116018646A (zh) * 2020-05-22 2023-04-25 阿克图尔公司 用于表征无细胞核酸片段的方法
WO2021249825A1 (en) * 2020-06-08 2021-12-16 F. Hoffmann-La Roche Ag Methods and compositions for detecting structural rearrangements in a genome
KR20220074756A (ko) * 2020-11-27 2022-06-03 연세대학교 산학협력단 Pcr 과정 동안 생성되는 가닥들의 정보를 연결하여 하나의 클러스터를 만들고, 생성된 가닥들의 생성 순서를 추적할 수 있는 방법
CA3210985A1 (en) * 2021-03-12 2022-09-15 Sarah KANE Multiplexed genotyping assays with a single probe using fluorescent amplitude tuning
CN113025719B (zh) * 2021-04-20 2023-04-07 桂林医学院附属医院 预测肝癌复发的生物标志物及其应用
CN113388676B (zh) * 2021-06-16 2023-07-25 深圳雅济科技有限公司 一种用于检测结节性硬化症基因突变的探针集及其试剂盒
US20230002807A1 (en) * 2021-06-30 2023-01-05 Fluent Biosciences Inc. Methods and compositions for nucleic acid analysis
CN113621692B (zh) * 2021-10-12 2022-02-22 北京求臻医疗器械有限公司 人类fgfr1基因拷贝数变异核酸标准物质及其制备方法、及试剂盒
EP4423297A1 (en) * 2021-10-25 2024-09-04 GT Molecular, Inc. Off-target blocking sequences to improve target discrimination by polymerase chain reaction
WO2023154709A2 (en) * 2022-02-08 2023-08-17 The Trustees Of The University Of Pennsylvania Methods for rapid, scalable, amplified nucleic acid detection in situ
WO2024049476A1 (en) * 2022-08-31 2024-03-07 Immunocore Limited Compositions and methods for treating cancer that demonstrates decreasing levels of ctdna in a subject
WO2024111057A1 (ja) * 2022-11-22 2024-05-30 株式会社クオントディテクト がんの診断のためのプローブ/プライマーライブラリー

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2543786A1 (en) * 2003-10-24 2005-05-06 Mmi Genomics, Inc. Methods and systems for inferring traits to manage non-beef livestock
ES2668467T3 (es) * 2004-10-18 2018-05-18 Brandeis University Métodos de amplificación LATE y secuenciación de un ácido nucleico
US20070031865A1 (en) * 2005-07-07 2007-02-08 David Willoughby Novel Process for Construction of a DNA Library
KR101970908B1 (ko) * 2008-02-01 2019-04-19 더 제너럴 하스피탈 코포레이션 의학적 질환 및 병태의 진단, 예후, 및 치료에 있어서 미세소포체의 용도
CA2718887A1 (en) * 2008-03-19 2009-09-24 Existence Genetics Llc Genetic analysis
AU2010232439C1 (en) * 2009-04-02 2017-07-13 Fluidigm Corporation Multi-primer amplification method for barcoding of target nucleic acids
US20110237537A1 (en) * 2009-05-29 2011-09-29 Lombard Jay L Methods for assessment and treatment of mood disorders via single nucleotide polymorphisms analysis
US20110117559A1 (en) * 2009-11-13 2011-05-19 Integrated Dna Technologies, Inc. Small rna detection assays
WO2011140510A2 (en) * 2010-05-06 2011-11-10 Bioo Scientific Corporation Oligonucleotide ligation, barcoding and methods and compositions for improving data quality and throughput using massively parallel sequencing
CA2810931C (en) * 2010-09-24 2018-04-17 The Board Of Trustees Of The Leland Stanford Junior University Direct capture, amplification and sequencing of target dna using immobilized primers
EP2659003A4 (en) * 2010-12-30 2014-05-21 Foundation Medicine Inc OPTIMIZATION OF MULTIGENIC ANALYSIS OF TUMOR SAMPLES
CN102534813B (zh) * 2011-11-15 2013-09-04 杭州联川生物技术有限公司 构建中小片段rna测序文库的方法

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JP2019170390A (ja) 2019-10-10
JP2016513959A (ja) 2016-05-19
WO2014130890A1 (en) 2014-08-28
CA2902207A1 (en) 2014-08-28
EP2959016A4 (en) 2016-10-12
SG11201506660RA (en) 2015-09-29
US20160186267A1 (en) 2016-06-30
US20160222427A1 (en) 2016-08-04
CN105339507A (zh) 2016-02-17
GB201516569D0 (en) 2015-11-04
US20180148756A1 (en) 2018-05-31
GB2526736A (en) 2015-12-02
EP2959016A1 (en) 2015-12-30

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