HK1204330A1 - 因子 組合物及其製備和使用方法 - Google Patents

因子 組合物及其製備和使用方法

Info

Publication number
HK1204330A1
HK1204330A1 HK15104912.0A HK15104912A HK1204330A1 HK 1204330 A1 HK1204330 A1 HK 1204330A1 HK 15104912 A HK15104912 A HK 15104912A HK 1204330 A1 HK1204330 A1 HK 1204330A1
Authority
HK
Hong Kong
Prior art keywords
viii
making
methods
same
compositions
Prior art date
Application number
HK15104912.0A
Other languages
English (en)
Inventor
Volker Schellenberger
Pei-Yun Chang
Fatbardha Varfaj
Sheng Ding
Joshua Silverman
Chia-Wei Wang
Benjamin Spink
Willem P Stemmer
Nathan Geething
John Kulman
Tongyao Liu
Garabet G Toby
Haiyan Jiang
Robert Peters
Deping Wang
Baisong Mei
Original Assignee
Amunix Operating Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amunix Operating Inc filed Critical Amunix Operating Inc
Publication of HK1204330A1 publication Critical patent/HK1204330A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
HK15104912.0A 2012-02-15 2015-05-22 因子 組合物及其製備和使用方法 HK1204330A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261599400P 2012-02-15 2012-02-15
PCT/US2012/046326 WO2013122617A1 (en) 2012-02-15 2012-07-11 Factor viii compositions and methods of making and using same

Publications (1)

Publication Number Publication Date
HK1204330A1 true HK1204330A1 (zh) 2015-11-13

Family

ID=48984579

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15104912.0A HK1204330A1 (zh) 2012-02-15 2015-05-22 因子 組合物及其製備和使用方法

Country Status (29)

Country Link
US (3) US10421798B2 (zh)
EP (3) EP4194465A1 (zh)
JP (6) JP6256882B2 (zh)
KR (1) KR102097263B1 (zh)
CN (3) CN111574632A (zh)
AU (3) AU2012327217B2 (zh)
BR (1) BR112014020694A2 (zh)
CA (1) CA2864904C (zh)
CL (2) CL2014002166A1 (zh)
CO (1) CO7051009A2 (zh)
CY (1) CY1122800T1 (zh)
DK (2) DK2814840T3 (zh)
EA (1) EA201491470A1 (zh)
ES (2) ES2771208T3 (zh)
FI (1) FI3564260T3 (zh)
HK (1) HK1204330A1 (zh)
HR (2) HRP20221531T1 (zh)
HU (2) HUE060629T2 (zh)
IL (1) IL234108B (zh)
LT (2) LT3564260T (zh)
MX (2) MX369862B (zh)
MY (1) MY188897A (zh)
PH (2) PH12014501849B1 (zh)
PL (2) PL2814840T3 (zh)
PT (2) PT3564260T (zh)
RS (2) RS63870B1 (zh)
SG (2) SG10201606783RA (zh)
SI (2) SI3564260T1 (zh)
WO (1) WO2013122617A1 (zh)

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LT2804623T (lt) 2012-01-12 2019-12-10 Bioverativ Therapeutics Inc Chimeriniai viii faktoriaus polipeptidai ir jų panaudojimas
HUE043537T2 (hu) 2012-02-15 2019-08-28 Bioverativ Therapeutics Inc Rekombináns VIII faktor fehérjék
RS63870B1 (sr) 2012-02-15 2023-01-31 Bioverativ Therapeutics Inc Sastavi faktora viii i postupci za pravljenje i upotrebu istih
SG11201405276PA (en) 2012-02-27 2014-10-30 Amunix Operating Inc Xten conjugate compositions and methods of making same
LT2882450T (lt) 2012-07-11 2020-03-25 Bioverativ Therapeutics Inc. Faktoriaus viii komplekso su xten ir von vilebrando faktoriumi baltymas ir jo panaudojimas
RS61387B1 (sr) 2013-02-15 2021-02-26 Bioverativ Therapeutics Inc Gen optimizovanog faktora viii
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EP3013359A4 (en) * 2013-06-28 2017-01-25 Biogen MA Inc. Thrombin cleavable linker
US10548953B2 (en) 2013-08-14 2020-02-04 Bioverativ Therapeutics Inc. Factor VIII-XTEN fusions and uses thereof
WO2015023894A1 (en) 2013-08-14 2015-02-19 Biogen Idec Ma Inc. Recombinant factor viii proteins
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US11008561B2 (en) 2014-06-30 2021-05-18 Bioverativ Therapeutics Inc. Optimized factor IX gene
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CN107392315B (zh) * 2017-07-07 2021-04-09 中南大学 一种优化大脑情感学习模型的乳腺癌数据分类方法
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WO2019222682A1 (en) 2018-05-18 2019-11-21 Bioverativ Therapeutics Inc. Methods of treating hemophilia a
US20200069817A1 (en) 2018-08-09 2020-03-05 Bioverativ Therapeutics Inc. Nucleic acid molecules and uses thereof for non-viral gene therapy
WO2020086686A2 (en) * 2018-10-23 2020-04-30 The Children's Hospital Of Philadelphia Compositions and methods for modulating factor viii function
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