HK1141806A1 - Process for preparing 5-fluoro-1h-pyrazolo[3,4-b]pyridin-3-amine and derivatives thereof 5--1h-[34-b]-3- - Google Patents

Process for preparing 5-fluoro-1h-pyrazolo[3,4-b]pyridin-3-amine and derivatives thereof 5--1h-[34-b]-3-

Info

Publication number
HK1141806A1
HK1141806A1 HK10108334.6A HK10108334A HK1141806A1 HK 1141806 A1 HK1141806 A1 HK 1141806A1 HK 10108334 A HK10108334 A HK 10108334A HK 1141806 A1 HK1141806 A1 HK 1141806A1
Authority
HK
Hong Kong
Prior art keywords
pyrazolo
pyridin
fluoro
amine
derivatives
Prior art date
Application number
HK10108334.6A
Other languages
English (en)
Chinese (zh)
Inventor
‧吉米內斯
‧克裡爾
‧米勒
‧格林
高淮
‧哈蒙
‧德洛斯
Original Assignee
沃泰克斯藥物股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 沃泰克斯藥物股份有限公司 filed Critical 沃泰克斯藥物股份有限公司
Publication of HK1141806A1 publication Critical patent/HK1141806A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
HK10108334.6A 2007-07-31 2010-09-02 Process for preparing 5-fluoro-1h-pyrazolo[3,4-b]pyridin-3-amine and derivatives thereof 5--1h-[34-b]-3- HK1141806A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95301907P 2007-07-31 2007-07-31
PCT/US2008/071714 WO2009018415A1 (en) 2007-07-31 2008-07-31 Process for preparing 5-fluoro-1h-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof

Publications (1)

Publication Number Publication Date
HK1141806A1 true HK1141806A1 (en) 2010-11-19

Family

ID=39884162

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10108334.6A HK1141806A1 (en) 2007-07-31 2010-09-02 Process for preparing 5-fluoro-1h-pyrazolo[3,4-b]pyridin-3-amine and derivatives thereof 5--1h-[34-b]-3-

Country Status (13)

Country Link
US (2) US8242272B2 (xx)
EP (1) EP2176261B1 (xx)
JP (2) JP5553751B2 (xx)
CN (1) CN101790532B (xx)
AR (1) AR067762A1 (xx)
AU (1) AU2008282156B2 (xx)
CA (1) CA2694499A1 (xx)
ES (1) ES2400104T3 (xx)
HK (1) HK1141806A1 (xx)
MX (1) MX2010001137A (xx)
NZ (1) NZ582879A (xx)
TW (1) TW200916468A (xx)
WO (1) WO2009018415A1 (xx)

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DE102012200354A1 (de) 2012-01-11 2013-07-11 Bayer Intellectual Property Gmbh Heteroaryl-substituierte Pyrazolopyridine und ihre Verwendung
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JP6054967B2 (ja) 2011-09-02 2016-12-27 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH 置換アネレート化ピリミジンおよびその使用
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DE102012200351A1 (de) 2012-01-11 2013-07-11 Bayer Pharma Aktiengesellschaft Substituierte annellierte Pyrimidine und ihre Verwendung
WO2013076168A1 (de) 2011-11-25 2013-05-30 Bayer Pharma Aktiengesellschaft Verfahren zur herstellung von substituierten 5-fluor-1h-pyrazolopyridinen
DE102012200360A1 (de) 2012-01-11 2013-07-11 Bayer Intellectual Property Gmbh Substituierte Triazine und ihre Verwendung
DE102012200349A1 (de) 2012-01-11 2013-07-11 Bayer Intellectual Property Gmbh Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung
DE102012200352A1 (de) 2012-01-11 2013-07-11 Bayer Intellectual Property Gmbh Substituierte, annellierte Imidazole und Pyrazole und ihre Verwendung
ES2644781T3 (es) 2012-03-06 2017-11-30 Bayer Intellectual Property Gmbh Azabiciclos sustituidos y su uso
JP6386478B2 (ja) 2013-02-21 2018-09-05 アドヴェリオ・ファーマ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング メチル{4,6−ジアミノ−2−[1−(2−フルオロベンジル)−1h−ピラゾロ[3,4−b]ピリジノ−3−イル]ピリミジノ−5−イル}メチルカルバメートの形態
MA38365A1 (fr) 2013-03-01 2017-09-29 Bayer Pharma AG Pyrimidines annelées à subsitution trifluorométhyle et utilisation correspondante
PE20160201A1 (es) 2013-07-10 2016-05-06 Bayer Pharma AG Bencil-1h-pirazol[3,4-b]piridinas y su uso
EP3068776B1 (en) 2013-11-13 2019-05-29 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
SG10201804021TA (en) 2013-11-13 2018-07-30 Vertex Pharma Methods of preparing inhibitors of influenza viruses replication
WO2016183116A1 (en) 2015-05-13 2016-11-17 Vertex Pharmaceuticals Incorporated Methods of preparing inhibitors of influenza viruses replication
JP6857617B2 (ja) 2015-05-13 2021-04-14 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated インフルエンザウイルスの複製の阻害剤
TWI787018B (zh) * 2015-11-02 2022-12-11 美商纜圖藥品公司 轉染過程重排之抑制劑
WO2017121700A1 (de) 2016-01-15 2017-07-20 Bayer Pharma Aktiengesellschaft 1,3-disubstituierte 1h-pyrazolo[3,4-b]pyridin- derivate und ihre verwendung als stimulatoren der löslichen guanylatcyclase
CN108003092B (zh) * 2017-12-21 2021-04-02 重庆中邦科技有限公司 一种2,3-二氯吡啶的合成方法

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US8598361B2 (en) 2013-12-03
WO2009018415A1 (en) 2009-02-05
NZ582879A (en) 2012-03-30
EP2176261A1 (en) 2010-04-21
JP2014055160A (ja) 2014-03-27
US20120232275A1 (en) 2012-09-13
US8242272B2 (en) 2012-08-14
MX2010001137A (es) 2010-03-31
US20100184980A1 (en) 2010-07-22
JP2010535241A (ja) 2010-11-18
CA2694499A1 (en) 2009-02-05
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ES2400104T3 (es) 2013-04-05
JP5553751B2 (ja) 2014-07-16

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