HK1057885A1 - Succinate salt of o-desmethyl-venlafaxine o-desmethyl-venlafaxine - Google Patents
Succinate salt of o-desmethyl-venlafaxine o-desmethyl-venlafaxineInfo
- Publication number
- HK1057885A1 HK1057885A1 HK04100742A HK04100742A HK1057885A1 HK 1057885 A1 HK1057885 A1 HK 1057885A1 HK 04100742 A HK04100742 A HK 04100742A HK 04100742 A HK04100742 A HK 04100742A HK 1057885 A1 HK1057885 A1 HK 1057885A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- desmethyl
- venlafaxine
- succinate salt
- succinate
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/10—Succinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26821401P | 2001-02-12 | 2001-02-12 | |
US29796301P | 2001-06-13 | 2001-06-13 | |
PCT/US2002/004103 WO2002064543A2 (fr) | 2001-02-12 | 2002-02-11 | Nouveau sel de succinate de o-desmethyl-venlafaxine |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1057885A1 true HK1057885A1 (en) | 2004-04-23 |
Family
ID=26952945
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK04100742A HK1057885A1 (en) | 2001-02-12 | 2004-02-05 | Succinate salt of o-desmethyl-venlafaxine o-desmethyl-venlafaxine |
Country Status (31)
Country | Link |
---|---|
US (5) | US6673838B2 (fr) |
EP (3) | EP2319826A1 (fr) |
JP (1) | JP4220243B2 (fr) |
KR (1) | KR100875610B1 (fr) |
CN (2) | CN100567253C (fr) |
AR (2) | AR032671A1 (fr) |
AT (1) | ATE369330T1 (fr) |
AU (1) | AU2002250058B2 (fr) |
BR (1) | BR0207157A (fr) |
CA (2) | CA2666611A1 (fr) |
CY (1) | CY1106952T1 (fr) |
DE (1) | DE60221642T3 (fr) |
DK (1) | DK1360169T3 (fr) |
EA (1) | EA011451B1 (fr) |
ES (1) | ES2290281T5 (fr) |
HK (1) | HK1057885A1 (fr) |
HN (1) | HN2002000030A (fr) |
HU (1) | HUP0303128A3 (fr) |
IL (4) | IL157340A0 (fr) |
MX (1) | MXPA03007043A (fr) |
NO (1) | NO328807B1 (fr) |
NZ (1) | NZ539791A (fr) |
PA (1) | PA8539901A1 (fr) |
PE (1) | PE20020877A1 (fr) |
PL (2) | PL211788B1 (fr) |
PT (1) | PT1360169E (fr) |
SI (1) | SI1360169T1 (fr) |
TW (1) | TWI318201B (fr) |
UY (1) | UY27175A1 (fr) |
WO (1) | WO2002064543A2 (fr) |
ZA (1) | ZA200307116B (fr) |
Families Citing this family (114)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000026234A1 (fr) | 1998-10-30 | 2000-05-11 | Ajinomoto Co., Inc. | Procede de cristallisation pour la formation de cristaux stables de derive d'aspartame |
US6342533B1 (en) | 1998-12-01 | 2002-01-29 | Sepracor, Inc. | Derivatives of (−)-venlafaxine and methods of preparing and using the same |
EP1905757A1 (fr) * | 1999-04-06 | 2008-04-02 | Sepracor Inc. | Dérivés de venlafaxine et leurs procédés de préparation et d'utilisation |
US6673838B2 (en) * | 2001-02-12 | 2004-01-06 | Wyeth | Succinate salt of O-desmethyl-venlafaxine |
US20050244498A1 (en) * | 2001-09-14 | 2005-11-03 | Biovail Laboratories, Inc. | Modified-release compositions of at least one form of venlafaxine |
UA80543C2 (en) | 2001-12-04 | 2007-10-10 | Wyeth Corp | Method for the preparation of o-desmethylvenlafaxine |
US20030190351A1 (en) * | 2002-03-28 | 2003-10-09 | Synthon Bv | Extended release venlafaxine formulations |
WO2003103603A2 (fr) * | 2002-06-10 | 2003-12-18 | Wyeth | Nouveau sel de type formiate de o-desmethylvenlafaxine |
BR0313836A (pt) * | 2002-08-29 | 2005-06-21 | Arachnova Therapeutics Ltd | Novos usos terapêuticos de 4-(2-fluorofenil)-6-metil-2-(1-piperazinil)tieno[2,3-d]pi rimidina |
US7345096B2 (en) | 2002-10-15 | 2008-03-18 | Wyeth | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
ATE490788T1 (de) | 2003-04-25 | 2010-12-15 | Gilead Sciences Inc | Antivirale phosphonate analoge |
JP2004359665A (ja) * | 2003-05-30 | 2004-12-24 | Rohm & Haas Co | 生体利用性増強剤を含有する治療組成物 |
US7524846B2 (en) | 2003-10-14 | 2009-04-28 | Wyeth | Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use |
US7531543B2 (en) | 2003-10-14 | 2009-05-12 | Wyeth | Phenylpiperazine cycloalkanol derivatives and methods of their use |
US7419980B2 (en) | 2003-10-14 | 2008-09-02 | Wyeth | Fused-aryl and heteroaryl derivatives and methods of their use |
US7365076B2 (en) | 2003-10-14 | 2008-04-29 | Wyeth | Substituted aryl cycloalkanol derivatives and methods of their use |
US7402698B2 (en) | 2003-10-14 | 2008-07-22 | Wyeth | Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use |
US7491723B2 (en) | 2003-10-14 | 2009-02-17 | Wyeth | Alkanol and cycloalkanol-amine derivatives and methods of their use |
US7550485B2 (en) | 2003-10-14 | 2009-06-23 | Wyeth | Substituted N-heterocycle derivatives and methods of their use |
EP2052717A1 (fr) | 2004-02-06 | 2009-04-29 | Wyeth | Sels d'O-Desmethylvenlafaxines multiparticulaires et leurs utilisations |
US7414052B2 (en) | 2004-03-30 | 2008-08-19 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
US7517899B2 (en) | 2004-03-30 | 2009-04-14 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
US7439280B2 (en) * | 2004-04-06 | 2008-10-21 | Basf Corporation | Lignocellulosic composite material and method for preparing the same |
JP2008507550A (ja) * | 2004-07-22 | 2008-03-13 | ワイス | 神経系障害及び状態の処置方法 |
CN101022794A (zh) * | 2004-07-22 | 2007-08-22 | 惠氏公司 | 治疗神经系统障碍和病症的方法 |
AU2005266996A1 (en) * | 2004-07-22 | 2006-02-02 | Wyeth | Method for treating nervous system disorders and conditions |
EP1778251B1 (fr) | 2004-07-27 | 2011-04-13 | Gilead Sciences, Inc. | Conjugues de phosphonate nucleosidique comme agents anti-vih |
US20060228413A1 (en) * | 2005-02-28 | 2006-10-12 | Penwest Pharmaceuticals Co. | Controlled release venlafaxine formulations |
WO2006104791A1 (fr) * | 2005-03-31 | 2006-10-05 | Wyeth | Produit combine a base d'o-desmethylvenlafaxine et de bazedoxifene et utilisations de ce produit |
CN1955159B (zh) * | 2005-06-17 | 2010-11-24 | 山东绿叶制药有限公司 | 用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途 |
MX2008000249A (es) * | 2005-07-06 | 2008-03-18 | Sepracor Inc | Combinaciones de eszopiclona y o-desmetilvenlafaxina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y cognitivos. |
MX2008000680A (es) * | 2005-07-15 | 2008-03-14 | Wyeth Corp | Inhibidor de la retoma dual de norepinefrina y serotonina altamente selectivo y su uso. |
US7687520B2 (en) * | 2005-07-15 | 2010-03-30 | Wyeth Llc | Serotonin and norepinephrine reuptake inhibitors and uses thereof |
US7595340B2 (en) * | 2005-07-15 | 2009-09-29 | Wyeth | Serotonin and norepinephrine reuptake inhibitor and uses thereof |
US20070021488A1 (en) * | 2005-07-21 | 2007-01-25 | Wyeth | Method for treating nervous system disorders and conditions |
GT200600396A (es) * | 2005-09-07 | 2007-04-23 | Dispositivos para la aplicacion de medicamentos transdermicos conteniendo o-desmetil venlafaxina (odv) o sus sales | |
GT200600397A (es) * | 2005-09-07 | 2007-08-28 | Formulas topicas conteniendo o-desmetil venlafaxina (odv) o sus sales | |
CN1332946C (zh) * | 2005-10-21 | 2007-08-22 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 作用于中枢神经系统的前药 |
HUE027865T2 (en) | 2005-12-01 | 2016-11-28 | Auspex Pharmaceuticals Inc | Substituted phenyl ethylamines with serotonergic and / or norepinephrine activity |
US7612210B2 (en) * | 2005-12-05 | 2009-11-03 | Wyeth | Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols |
WO2007071404A1 (fr) * | 2005-12-20 | 2007-06-28 | Synthon B.V. | Procédé de fabrication de la desvenlafaxine |
JP2008546718A (ja) | 2006-04-17 | 2008-12-25 | テバ ファーマシューティカル インダストリーズ リミティド | 実質的に純粋なo−デスメチルベンラファキシン及びその調製方法。 |
MX2007016179A (es) | 2006-04-17 | 2008-03-11 | Teva Pharma | Formas cristalinas de o-desmetilvenlafaxina. |
WO2007136650A2 (fr) * | 2006-05-16 | 2007-11-29 | Gilead Sciences, Inc. | Méthode et composition pour le traitement d'hémopathies malignes |
US20090137846A1 (en) * | 2006-07-26 | 2009-05-28 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-Desmethylvenlafaxine |
CA2656166A1 (fr) * | 2006-07-26 | 2008-01-31 | Teva Pharmaceutical Industries Ltd. | Procedes pour synthetiser le compose o-desmethylvenlafaxine |
US20090069601A1 (en) * | 2006-07-26 | 2009-03-12 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-desmethylvenlafaxine |
EP1934168A2 (fr) * | 2006-07-26 | 2008-06-25 | Teva Pharmaceutical Industries Ltd | Tridesmethylvenlafaxine et procédés pour la préparation de desmethylvenlafaxine |
US20080221356A1 (en) * | 2006-07-26 | 2008-09-11 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-desmethylvenlafaxine |
EP2061750A2 (fr) * | 2006-08-04 | 2009-05-27 | Medichem, S.A. | Procédé amélioré de synthèse d'une base libre de desvenlafaxine et de sels ou solvates de celle-ci |
CA2659295A1 (fr) * | 2006-08-08 | 2008-02-14 | Generics [Uk] Limited | Nouvelle forme hydratee de succinate d'o-desmethyl-venlafaxine |
CA2665381A1 (fr) * | 2006-10-18 | 2008-04-24 | Generics [Uk] Limited | Formes polymorphes de succinate d'o-desmethyl-venlafaxine |
US20080261895A1 (en) * | 2006-10-25 | 2008-10-23 | Wyeth | Isolated hydroxy and n-oxide metabolites and derivatives of O-desmethylvenlafaxine and methods of treatment |
ES2360014T3 (es) * | 2006-12-21 | 2011-05-31 | Pfizer Products Inc. | Sal succinato de 2-((4-(1-metil-4-(piridin-4-il)-1h-pirazol-3-il)-fenoxi)metil)quinolina. |
WO2009027766A2 (fr) * | 2006-12-22 | 2009-03-05 | Medichem, S.A. | Nouvelles formes solides cristallines de la base o-desvenlafaxine |
US7820716B2 (en) * | 2007-01-08 | 2010-10-26 | Mai De Ltd | Crystalline polymorphs of desvenlafaxine succinate and their preparations |
WO2008090465A2 (fr) * | 2007-01-22 | 2008-07-31 | Medichem, S.A. | Procédé amélioré de synthèse d'une base libre de la desvenlafaxine et de sels ou de solvates de celle-ci |
WO2008093142A1 (fr) * | 2007-01-31 | 2008-08-07 | Generics [Uk] Limited | Procede de preparation de o-desmethyl venlafaxine |
CN101663263A (zh) | 2007-02-21 | 2010-03-03 | 塞普拉柯公司 | 包含(-)-o-去甲基文拉法辛的固体形式及其用途 |
WO2008110338A1 (fr) * | 2007-03-09 | 2008-09-18 | Synthon B.V. | Polymorphe de succinate de desvenlafaxine |
EP2049465A2 (fr) * | 2007-03-14 | 2009-04-22 | Teva Pharmaceutical Industries Ltd. | Procédés pour préparer des états solides de succinate d'o-desméthylvenlafaxine |
EP3103790B1 (fr) | 2007-03-15 | 2018-05-09 | Auspex Pharmaceuticals, Inc. | Phénétylamine substituée ayant une activité sérotoninergique et/ou norépinéphrinergique |
WO2008156748A2 (fr) * | 2007-06-15 | 2008-12-24 | Teva Pharmaceutical Industries Ltd. | Formes cristallines du succinate de o-desméthylvenlafaxine |
WO2009009665A2 (fr) * | 2007-07-12 | 2009-01-15 | Dr. Reddy's Laboratories, Ltd. | O-desméthylvenlafaxine |
WO2009010990A2 (fr) * | 2007-07-16 | 2009-01-22 | Matrix Laboratories Limited | Procédé pour préparer des formes polymorphes de succinate de o-desméthylvenlafaxine |
WO2009017813A1 (fr) * | 2007-08-02 | 2009-02-05 | Teva Pharmaceutical Industries Ltd. | Saccharinate d'o-desméthyl-venlafaxine |
US20090076162A1 (en) * | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched desvenlafaxine |
WO2009049354A1 (fr) * | 2007-10-16 | 2009-04-23 | Alphapharm Pty Ltd | Formulation pharmaceutique à libération contrôlée |
EP2212275A2 (fr) * | 2007-10-22 | 2010-08-04 | Actavis Group PTC EHF | Formes solides de sels de (±)-o-déméthylvenlafaxine |
EP2200968A1 (fr) | 2007-10-26 | 2010-06-30 | Generics Ýuk¨Limited | Procédé de préparation de o-desméthylvenlafaxine |
WO2009070311A2 (fr) * | 2007-11-26 | 2009-06-04 | Teva Pharmaceutical Industries Ltd. | Formes cristallines de fumarate de o-desméthylvenlafaxine |
EP2085377A1 (fr) | 2008-01-29 | 2009-08-05 | LEK Pharmaceuticals D.D. | Nouveaux sels d'O-desméthyl-venlafaxine |
WO2009114685A2 (fr) * | 2008-03-12 | 2009-09-17 | Dr. Reddy's Laboratories Ltd. | Sels d’o-desméthylvenlafaxine |
WO2009118758A2 (fr) * | 2008-03-24 | 2009-10-01 | Sun Pharmaceutical Industries Ltd. | Nouvelles formes cristallines de succinate de desvenlafaxine |
IN2008CH00818A (fr) * | 2008-04-01 | 2009-10-09 | Actavis Group Ptc Ehf | |
KR100965527B1 (ko) | 2008-05-08 | 2010-06-23 | 제일약품주식회사 | 신규(4-(2-(디메틸아미노)-1-(1-하이드록시사이클로헥실)에틸)페녹시)포스페이트 또는 이의 약학적으로 허용가능한 염,이의 제조방법 및 이를 유효성분으로 함유하는 중추신경계질환 예방 및 치료용 조성물 |
EP2119696A1 (fr) | 2008-05-16 | 2009-11-18 | Krka | Préparation de sels de O-desméthylvenlafaxine |
EP2119695A1 (fr) | 2008-05-16 | 2009-11-18 | Krka | Préparation de sels de O-desméthylvenlafaxine |
WO2010008735A2 (fr) * | 2008-06-16 | 2010-01-21 | Teva Pharmaceutical Industries Ltd. | États solides de sels de o-desméthylvenlafaxine |
AU2009268681B2 (en) | 2008-07-08 | 2014-10-02 | Gilead Sciences, Inc. | Salts of HIV inhibitor compounds |
US20100016638A1 (en) * | 2008-07-21 | 2010-01-21 | Zdenko Hamersak | Method for preparation of o-desmethylvenlafaxine using polythiolates |
US20110263718A1 (en) * | 2008-07-30 | 2011-10-27 | Generics [Uk] Limited | Process for the preparation of o-desmethylvenlafaxine |
KR101041960B1 (ko) * | 2008-08-14 | 2011-06-16 | 주식회사 루미맥스테크놀러지 | 파워 led를 구비하는 램프 장치 |
EP2191822A1 (fr) | 2008-11-26 | 2010-06-02 | LEK Pharmaceuticals d.d. | Compositions pharmaceutiques à libération contrôlée comprenant de l' O-desméthyl-venlafaxine |
CZ301503B6 (cs) | 2008-11-27 | 2010-03-24 | Zentiva, A. S. | Zpusob prípravy desvenlafaxinu a jeho solí |
ES2343050B1 (es) * | 2008-12-16 | 2011-06-14 | Chemo Iberica, S.A. | Procedimiento para la preparacion de desvenlafaxina y sus sales de adicion de acido farmaceuticamente aceptables. |
CZ200969A3 (cs) * | 2009-02-06 | 2010-06-30 | Zentiva, K.S. | Nové soli desvenlafaxinu a zpusob jejich prípravy |
CZ2009454A3 (cs) | 2009-07-15 | 2010-11-10 | Zentiva, K. S. | Zpusob prípravy desvenlafaxinu a jeho solí |
NZ597550A (en) | 2009-07-16 | 2013-08-30 | Cipla Ltd | Process for the preparation of o-desmethyl venlafaxine and intermediate for use therein |
US20110098506A1 (en) * | 2009-10-26 | 2011-04-28 | Intas Pharmaceuticals Limited | Method of preparing o-desmethylvenlafaxine |
WO2011072703A1 (fr) | 2009-12-16 | 2011-06-23 | Pharmathen S.A. | Procédé de préparation d'o-desméthyl-venlafaxine et ses sels |
US20110184067A1 (en) * | 2010-01-25 | 2011-07-28 | Intas Pharmaceuticals Ltd. | O-desmethylvenlafaxine succinate polymorph & process for preparing thereof |
EP2539313A2 (fr) | 2010-03-29 | 2013-01-02 | Pliva Hrvatska D.O.O. | Formes cristallines du fumarate de o-desméthylvenlafaxine |
MX2012010659A (es) * | 2010-03-31 | 2013-03-05 | Wockhardt Ltd | Composicion farmaceutica de liberacion modificada que comprende desvenlafaxina o sus sales. |
CZ303249B6 (cs) * | 2010-04-06 | 2012-06-20 | Zentiva, K.S. | Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu |
CN102212014B (zh) * | 2010-04-09 | 2013-12-25 | 江苏豪森医药集团有限公司 | O-去甲基-文拉法辛的谷氨酸盐的晶型、其制备方法及其在医药上的应用 |
WO2011141791A2 (fr) | 2010-05-14 | 2011-11-17 | Alembic Limited | Formulations à libération prolongée de la base desvenlafaxine |
CN102249936B (zh) * | 2010-05-19 | 2014-09-17 | 江苏豪森医药集团有限公司 | O-去甲基文拉法辛盐酸盐的水合物及其制备方法 |
RU2576665C2 (ru) | 2010-10-01 | 2016-03-10 | Йоуксин ЛИ | Полиморфы 4-[2-диметиламино-1-(1-гидроксициклогексил)этил]фенил 4-метилбензоата гидрохлорида, способы их получения и использование |
US8933123B2 (en) | 2010-10-08 | 2015-01-13 | Cadila Healthcare Limited | Polymorphic forms of O-desmethyl-venlafaxine succinate |
US20140010883A1 (en) | 2011-03-17 | 2014-01-09 | Lupin Limited | Controlled release pharmaceutical compositions of selective serotonin reuptake inhibitor |
BR112013025766A2 (pt) | 2011-04-12 | 2016-12-20 | Lupin Ltd | composições farmacêuticas de liberação modificada de desvenlafaxina |
US8481596B2 (en) | 2011-06-08 | 2013-07-09 | Lupin Limited | Polymomorph of desvenlafaxine benzoate |
UY35091A (es) * | 2012-10-24 | 2014-05-30 | Onyx Therapeutics Inc | Formulaciones de liberacion modificada para oprozomib |
CN104666291A (zh) * | 2013-11-26 | 2015-06-03 | 山东绿叶制药有限公司 | 去甲基文拉法辛苯甲酸酯类化合物在制备改善性功能障碍药物中的应用 |
CN104352469A (zh) * | 2014-11-20 | 2015-02-18 | 哈尔滨圣吉药业股份有限公司 | 一种琥珀酸去甲文拉法辛缓释片及其制备方法 |
CN106146323B (zh) * | 2015-04-03 | 2021-05-25 | 石药集团中奇制药技术(石家庄)有限公司 | 一种琥珀酸去甲文拉法辛一水合物新晶型及制备方法 |
MX367362B (es) | 2016-06-29 | 2019-08-16 | Alparis Sa De Cv | Nuevas formas solidas de desvenlafaxina. |
WO2018146529A1 (fr) * | 2017-02-09 | 2018-08-16 | R L Finechem Private Limited | Procédé de préparation de 1-[2-(diméthylamino)-1-(4-hydroxyphényl) éthyl]-cyclohexanol et de ses sels |
CN107082745A (zh) * | 2017-04-21 | 2017-08-22 | 上海华源医药科技发展有限公司 | 一种改进的ⅰ型去甲文拉法辛琥珀酸盐的生产方法 |
AU2018301395A1 (en) * | 2017-07-11 | 2020-02-06 | Universal Stabilization Technologies, Inc. | Method for Preserving Biological Materials |
EP3960740B1 (fr) | 2017-08-01 | 2023-11-15 | Gilead Sciences, Inc. | Formes crystallines de vanillate de ((s)-((((2r,5r)-5-(6-amino-9h-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl)oxy)méthyl)(phénoxy)phosphoryl)-l-alaninate éthyilique (gs-9131) pour le traitement d'infections virales |
TWI805601B (zh) | 2017-08-11 | 2023-06-21 | 南韓商愛茉莉太平洋股份有限公司 | 醫藥組成物及抑制其形成結晶的方法 |
TR201820634A2 (tr) | 2018-12-27 | 2020-07-21 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Desvenlafaksi̇ni̇n kati oral farmasöti̇k kompozi̇syonlari |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
US4535186A (en) | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
IE56324B1 (en) | 1982-12-13 | 1991-06-19 | American Home Prod | Phenethylamine derivatives and intermediates therefor |
US4761501A (en) | 1983-10-26 | 1988-08-02 | American Home Products Corporation | Substituted phenylacetamides |
IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
GB8902209D0 (en) | 1989-02-01 | 1989-03-22 | Wyeth John And Brother Limited | Preparation of cyclohexanol derivatives and novel thioamide intermediates |
IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
WO1994000114A1 (fr) | 1992-06-23 | 1994-01-06 | Sepracor Inc. | Procedes et compositions utilises pour traiter la depression et d'autres affections avec de la sibutramine (-) optiquement pure |
WO1994000047A1 (fr) | 1992-06-23 | 1994-01-06 | Sepracor Inc. | Procedes et compositions utilises pour traiter la depression et d'autres affections avec de la sibutramine (+) optiquement pure |
US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
DK0639374T3 (da) | 1993-06-28 | 2002-05-06 | American Home Prod | Nye behandlingsmetoder ved anvendelse af phenethylderivater |
TW344661B (en) * | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
EP1245228A3 (fr) * | 1994-02-14 | 2002-10-09 | Wyeth | Venlafaxine et ses analogues pour induire une amélioration des fonctions cognitives |
US5594586A (en) * | 1994-05-02 | 1997-01-14 | The United States Of America As Represented By The Secretary Of The Air Force | Photorefractive limiting quadratic processor |
IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
US5506270A (en) † | 1995-01-30 | 1996-04-09 | American Home Products Corporation | Venlafaxine in the treatment of hypothalamic amenorrhea in non-depressed women |
US5554383A (en) | 1995-04-06 | 1996-09-10 | Trustees Of Tufts College | Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression |
US6274171B1 (en) | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
WO1997044317A2 (fr) † | 1996-05-21 | 1997-11-27 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Nouveaux procedes de o-demethylation et n-deprotection |
EP1029536B1 (fr) † | 1997-10-01 | 2007-11-28 | Novadel Pharma Inc. | Pulverisateur buccal non polaire |
US6342533B1 (en) | 1998-12-01 | 2002-01-29 | Sepracor, Inc. | Derivatives of (−)-venlafaxine and methods of preparing and using the same |
US6197828B1 (en) * | 1998-12-01 | 2001-03-06 | Sepracor, Inc. | Derivatives of (+)-venlafaxine and methods of preparing and using the same |
EP1905757A1 (fr) * | 1999-04-06 | 2008-04-02 | Sepracor Inc. | Dérivés de venlafaxine et leurs procédés de préparation et d'utilisation |
AU768022B2 (en) † | 1999-05-27 | 2003-11-27 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
AU5738700A (en) * | 1999-06-15 | 2001-01-02 | American Home Products Corporation | Enantiomers of o-desmethyl venlafaxine |
US20020022662A1 (en) | 1999-06-15 | 2002-02-21 | American Home Products Corporation | Enantiomers of O-desmethyl venlafaxine |
US6673838B2 (en) * | 2001-02-12 | 2004-01-06 | Wyeth | Succinate salt of O-desmethyl-venlafaxine |
UA80543C2 (en) * | 2001-12-04 | 2007-10-10 | Wyeth Corp | Method for the preparation of o-desmethylvenlafaxine |
WO2003103603A2 (fr) | 2002-06-10 | 2003-12-18 | Wyeth | Nouveau sel de type formiate de o-desmethylvenlafaxine |
TWI306092B (en) | 2003-03-11 | 2009-02-11 | Wyeth Corp | Process for preparation of phenethylamine derivatives |
EP2052717A1 (fr) | 2004-02-06 | 2009-04-29 | Wyeth | Sels d'O-Desmethylvenlafaxines multiparticulaires et leurs utilisations |
-
2002
- 2002-02-11 US US10/073,743 patent/US6673838B2/en not_active Expired - Lifetime
- 2002-02-11 PT PT02718949T patent/PT1360169E/pt unknown
- 2002-02-11 EA EA200300873A patent/EA011451B1/ru not_active IP Right Cessation
- 2002-02-11 WO PCT/US2002/004103 patent/WO2002064543A2/fr active Application Filing
- 2002-02-11 AU AU2002250058A patent/AU2002250058B2/en not_active Expired
- 2002-02-11 MX MXPA03007043A patent/MXPA03007043A/es active IP Right Grant
- 2002-02-11 HU HU0303128A patent/HUP0303128A3/hu unknown
- 2002-02-11 IL IL15734002A patent/IL157340A0/xx unknown
- 2002-02-11 DE DE60221642.7T patent/DE60221642T3/de not_active Expired - Lifetime
- 2002-02-11 BR BR0207157-6A patent/BR0207157A/pt not_active Application Discontinuation
- 2002-02-11 KR KR1020037010561A patent/KR100875610B1/ko active IP Right Review Request
- 2002-02-11 CA CA002666611A patent/CA2666611A1/fr not_active Abandoned
- 2002-02-11 DK DK02718949T patent/DK1360169T3/da active
- 2002-02-11 NZ NZ539791A patent/NZ539791A/en not_active IP Right Cessation
- 2002-02-11 AT AT02718949T patent/ATE369330T1/de active
- 2002-02-11 JP JP2002564477A patent/JP4220243B2/ja not_active Expired - Lifetime
- 2002-02-11 EP EP10177304A patent/EP2319826A1/fr not_active Withdrawn
- 2002-02-11 SI SI200230609T patent/SI1360169T1/sl unknown
- 2002-02-11 CN CNB028081129A patent/CN100567253C/zh not_active Expired - Lifetime
- 2002-02-11 PL PL364605A patent/PL211788B1/pl unknown
- 2002-02-11 PL PL396568A patent/PL212943B1/pl unknown
- 2002-02-11 ES ES02718949.7T patent/ES2290281T5/es not_active Expired - Lifetime
- 2002-02-11 EP EP02718949.7A patent/EP1360169B2/fr not_active Expired - Lifetime
- 2002-02-11 EP EP07014868A patent/EP1864967A1/fr not_active Withdrawn
- 2002-02-11 CA CA002436668A patent/CA2436668C/fr not_active Expired - Lifetime
- 2002-02-11 PE PE2002000105A patent/PE20020877A1/es active IP Right Grant
- 2002-02-11 CN CN200910206182A patent/CN101671260A/zh active Pending
- 2002-02-11 HN HN2002000030A patent/HN2002000030A/es unknown
- 2002-02-12 AR ARP020100463A patent/AR032671A1/es not_active Application Discontinuation
- 2002-02-13 UY UY27175A patent/UY27175A1/es active IP Right Grant
- 2002-02-14 PA PA20028539901A patent/PA8539901A1/es unknown
- 2002-02-15 TW TW091102559A patent/TWI318201B/zh not_active IP Right Cessation
-
2003
- 2003-08-11 NO NO20033538A patent/NO328807B1/no not_active IP Right Cessation
- 2003-08-11 IL IL157340A patent/IL157340A/en active IP Right Grant
- 2003-09-04 US US10/654,756 patent/US20040044241A1/en not_active Abandoned
- 2003-09-11 ZA ZA2003/07116A patent/ZA200307116B/en unknown
-
2004
- 2004-02-05 HK HK04100742A patent/HK1057885A1/xx not_active IP Right Cessation
- 2004-11-10 US US10/985,292 patent/US7026508B2/en not_active Expired - Fee Related
-
2006
- 2006-01-18 US US11/334,223 patent/US7291347B2/en not_active Expired - Lifetime
-
2007
- 2007-08-20 US US11/841,638 patent/US20090018208A1/en not_active Abandoned
- 2007-10-22 CY CY20071101362T patent/CY1106952T1/el unknown
-
2009
- 2009-08-05 IL IL200255A patent/IL200255A/en active IP Right Grant
-
2010
- 2010-11-18 IL IL209444A patent/IL209444A/en active IP Right Grant
-
2011
- 2011-07-01 AR ARP110102372A patent/AR082076A2/es not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1057885A1 (en) | Succinate salt of o-desmethyl-venlafaxine o-desmethyl-venlafaxine | |
HK1208446A1 (en) | Derivatives of uk-2a uk-2a | |
HUP0500734A3 (en) | Use of 2-alkoxyphenyl-substituted imidazotriazinones | |
IL161178A0 (en) | MODIFICATIONS OF SOLID 3-sn-PHOSPHOGLYCERIDES | |
AU2003298725A8 (en) | Preparation of metallotexaphyrins | |
GB2377151B (en) | Fishing aid | |
IL156839A0 (en) | Use of chromanes | |
TW493722U (en) | Improved structure of lampwick | |
HU0104370D0 (en) | Honeyed schnaps of oerseg | |
IL165356A0 (en) | Preparation of 4-haloalkylkylnicotinamides | |
TW573751U (en) | Structure capable of preventing jaming | |
PL356853A1 (en) | Application of bacteriphages | |
TW526778U (en) | Structure of dual-purposed shoes | |
PL351273A1 (en) | Novel derivatives of benzoimidazole | |
TW511737U (en) | New structure of micro-radiator | |
TW510531U (en) | New structure of micro-radiator | |
TW510530U (en) | New structure of micro-radiator | |
TW494780U (en) | Structure of swimmeret | |
PL346451A1 (en) | Novel derivative of l-homophenylamine | |
GB0109520D0 (en) | Use of (di-substituted-phenyl)-pyrimidinyl-imidazole derivatives as njk-inhibitors | |
GB0125482D0 (en) | Uses of (s)-clenbuterol | |
TW589936U (en) | Improved structure of aqua-aerator | |
TW499920U (en) | Improved structure of hoverbed | |
TW567750U (en) | Improved structure of panty-hose | |
TW552879U (en) | Improved structure of hairclip |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AM43 | Amendment of standard patent following opposition or revocation proceedings in the designated patent office (acc. sect 43 patent ordinance) | ||
PE | Patent expired |
Effective date: 20220210 |