GR74687B - - Google Patents
Info
- Publication number
- GR74687B GR74687B GR64860A GR810164860A GR74687B GR 74687 B GR74687 B GR 74687B GR 64860 A GR64860 A GR 64860A GR 810164860 A GR810164860 A GR 810164860A GR 74687 B GR74687 B GR 74687B
- Authority
- GR
- Greece
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/197,416 US4351939A (en) | 1980-10-16 | 1980-10-16 | Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR74687B true GR74687B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-07-03 |
Family
ID=22729338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR64860A GR74687B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1980-10-16 | 1981-05-06 |
Country Status (33)
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT387221B (de) * | 1980-09-08 | 1988-12-27 | Bristol Myers Co | Verfahren zur herstellung des neuen |
| US4507303A (en) * | 1981-12-22 | 1985-03-26 | Sumitomo Chemical Company, Limited | Succinimide derivatives, compositions and method of use |
| US4452799A (en) * | 1981-12-23 | 1984-06-05 | Mead Johnson & Company | Benzisothiazole and benzisoxazole piperazine derivatives |
| JPS5945380U (ja) * | 1982-09-20 | 1984-03-26 | いすゞ自動車株式会社 | 車両用帯状体の固定装置 |
| US5066783A (en) * | 1986-05-20 | 1991-11-19 | Cohen Eric A | Antiviral peptides and means for treating herpes infections |
| US5015646A (en) * | 1987-08-28 | 1991-05-14 | Bristol-Myers Squibb Co. | Pharmaceutically useful polymorphic modification of buspirone |
| US4810789A (en) * | 1987-08-28 | 1989-03-07 | Bristol-Myers Company | Process for buspirone hydrochloride polymorphic crystalline form conversion |
| US5484788A (en) * | 1993-03-26 | 1996-01-16 | Beth Israel Hospital Association | Buspirone as a systemic immunosuppressant |
| US5631017A (en) * | 1993-03-26 | 1997-05-20 | Beth Israel Deaconess Medical Center, Inc. | Topical application of buspirone for treatment of pathological conditions associated with immune responses |
| FR2705098B1 (fr) * | 1993-05-10 | 1995-08-04 | Esteve Labor Dr | Procédé de préparation de 2-{4-[4-(chloro-1-pyrazolyl)butyl]1-pipérazinyl}pyrimidine (Lesopitron) . |
| CA2146593A1 (en) * | 1994-05-05 | 1995-11-06 | Jack Melton | Large-scale process for azapirone synthesis |
| US5521313A (en) * | 1994-05-05 | 1996-05-28 | Bristol-Myers Squibb Company | Process for preparing certain azapirones |
| US5637314A (en) * | 1995-06-07 | 1997-06-10 | Beth Israel Deaconess Medical Center, Inc. | Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis |
| TW200302728A (en) * | 2002-02-01 | 2003-08-16 | Novartis Ag | Substituted amines as IgE inhibitors |
| EP1919922B1 (en) * | 2005-08-30 | 2011-04-20 | Honeywell International Inc. | Method for synthesizing spiro quaternary ammonium systems |
| CN101089000B (zh) * | 2006-06-16 | 2011-01-05 | 北京大学 | 螺环哌嗪季铵盐类化合物及其制备方法和应用 |
| CN101362751B (zh) * | 2007-08-10 | 2011-05-11 | 成都科瑞德医药投资有限责任公司 | 枸橼酸坦度螺酮及其制备方法、制剂和质量控制方法 |
| EP2563791B1 (en) * | 2010-04-26 | 2014-12-24 | Sumitomo Dainippon Pharma Co., Ltd. | A process of a quaternary ammonium salt using phosphate |
| ES2594709T3 (es) * | 2010-04-26 | 2016-12-22 | Sumitomo Dainippon Pharma Co., Ltd. | Un proceso de preparación de una sal de amonio cuaternario |
| KR20210119954A (ko) | 2018-11-21 | 2021-10-06 | 케이스 웨스턴 리저브 유니버시티 | 단쇄 데히드로게나아제 활성을 조절하는 조성물 및 방법 |
| IT201900000657A1 (it) | 2019-01-16 | 2020-07-16 | Procos Spa | Processo per la sintesi di gepirone |
| CN117024414A (zh) * | 2023-08-11 | 2023-11-10 | 浙江九洲药业股份有限公司 | 一种枸橼酸坦度螺酮的合成方法 |
| CN119409681A (zh) * | 2024-03-28 | 2025-02-11 | 北京华素制药股份有限公司 | 一种盐酸丁螺环酮的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB948730A (en) * | 1959-04-08 | 1964-02-05 | Wellcome Found | Substituted cyclopropanes and related compounds |
| US3968216A (en) * | 1969-10-29 | 1976-07-06 | Smith Kline & French Laboratories Limited | Method of inhibiting histamine activity with guanidine compounds |
| BE759371A (fr) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
-
1980
- 1980-10-16 US US06/197,416 patent/US4351939A/en not_active Expired - Lifetime
-
1981
- 1981-04-27 ZA ZA00812759A patent/ZA812759B/xx unknown
- 1981-04-28 YU YU1103/81A patent/YU42565B/xx unknown
- 1981-04-30 NZ NZ196974A patent/NZ196974A/en unknown
- 1981-05-06 GR GR64860A patent/GR74687B/el unknown
- 1981-05-07 ES ES501994A patent/ES8206516A1/es not_active Expired
- 1981-05-08 AU AU70292/81A patent/AU524822B2/en not_active Expired
- 1981-05-27 JP JP7944381A patent/JPS5724384A/ja active Granted
- 1981-07-01 CY CY1325A patent/CY1325A/en unknown
- 1981-07-01 GB GB8120338A patent/GB2085436B/en not_active Expired
- 1981-08-11 CA CA000383588A patent/CA1175832A/en not_active Expired
- 1981-09-25 BE BE0/206077A patent/BE890509A/fr not_active IP Right Cessation
- 1981-09-28 LU LU83657A patent/LU83657A1/fr unknown
- 1981-09-30 DK DK433781A patent/DK148481C/da active
- 1981-10-12 FR FR8119153A patent/FR2492383A1/fr active Granted
- 1981-10-12 OA OA57515A patent/OA06920A/xx unknown
- 1981-10-13 FI FI813178A patent/FI75159C/fi not_active IP Right Cessation
- 1981-10-13 IT IT49476/81A patent/IT1143244B/it active
- 1981-10-13 NL NLAANVRAGE8104660,A patent/NL179055C/xx not_active IP Right Cessation
- 1981-10-13 SE SE8106060A patent/SE439167B/sv not_active IP Right Cessation
- 1981-10-14 CH CH6580/81A patent/CH647778A5/de not_active IP Right Cessation
- 1981-10-14 IL IL64047A patent/IL64047A/xx not_active IP Right Cessation
- 1981-10-15 HU HU843458A patent/HU187999B/hu unknown
- 1981-10-15 PT PT73824A patent/PT73824B/pt unknown
- 1981-10-15 HU HU812982A patent/HU185967B/hu not_active IP Right Cessation
- 1981-10-15 IE IE2420/81A patent/IE51646B1/en not_active IP Right Cessation
- 1981-10-16 AT AT0444681A patent/AT382153B/de not_active IP Right Cessation
- 1981-10-16 DE DE3141256A patent/DE3141256C2/de not_active Expired
- 1981-10-16 KR KR1019810003924D patent/KR890000465B1/ko not_active Expired
- 1981-10-16 KR KR8103924A patent/KR870000321B1/ko not_active Expired
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1982
- 1982-04-01 ES ES511079A patent/ES8304967A1/es not_active Expired
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1983
- 1983-03-09 SU SU833562184A patent/SU1342420A3/ru active
- 1983-06-21 YU YU1360/83A patent/YU43316B/xx unknown
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1985
- 1985-05-17 NL NL8501430A patent/NL8501430A/nl active Search and Examination
- 1985-12-17 JP JP60282152A patent/JPS61178983A/ja active Granted
- 1985-12-23 SG SG978/85A patent/SG97885G/en unknown
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1986
- 1986-01-13 KE KE3596A patent/KE3596A/xx unknown
- 1986-01-15 SE SE8600174A patent/SE447257B/sv not_active IP Right Cessation
- 1986-05-22 HK HK353/86A patent/HK35386A/xx not_active IP Right Cessation
- 1986-12-30 MY MY475/86A patent/MY8600475A/xx unknown