YU42565B - Process for producing spiro-quaternary ammonia halogenides - Google Patents

Process for producing spiro-quaternary ammonia halogenides

Info

Publication number
YU42565B
YU42565B YU1103/81A YU110381A YU42565B YU 42565 B YU42565 B YU 42565B YU 1103/81 A YU1103/81 A YU 1103/81A YU 110381 A YU110381 A YU 110381A YU 42565 B YU42565 B YU 42565B
Authority
YU
Yugoslavia
Prior art keywords
halogenides
quaternary ammonia
producing spiro
spiro
producing
Prior art date
Application number
YU1103/81A
Other languages
English (en)
Other versions
YU110381A (en
Inventor
C J Simms
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22729338&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU42565(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of YU110381A publication Critical patent/YU110381A/xx
Publication of YU42565B publication Critical patent/YU42565B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
YU1103/81A 1980-10-16 1981-04-28 Process for producing spiro-quaternary ammonia halogenides YU42565B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/197,416 US4351939A (en) 1980-10-16 1980-10-16 Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process

Publications (2)

Publication Number Publication Date
YU110381A YU110381A (en) 1983-12-31
YU42565B true YU42565B (en) 1988-10-31

Family

ID=22729338

Family Applications (2)

Application Number Title Priority Date Filing Date
YU1103/81A YU42565B (en) 1980-10-16 1981-04-28 Process for producing spiro-quaternary ammonia halogenides
YU1360/83A YU43316B (en) 1980-10-16 1983-06-21 Process for producing n-(2-pyrimidinyl)-piperazin-alkyl-aza-spiro-alkandiones

Family Applications After (1)

Application Number Title Priority Date Filing Date
YU1360/83A YU43316B (en) 1980-10-16 1983-06-21 Process for producing n-(2-pyrimidinyl)-piperazin-alkyl-aza-spiro-alkandiones

Country Status (33)

Country Link
US (1) US4351939A (xx)
JP (2) JPS5724384A (xx)
KR (2) KR890000465B1 (xx)
AT (1) AT382153B (xx)
AU (1) AU524822B2 (xx)
BE (1) BE890509A (xx)
CA (1) CA1175832A (xx)
CH (1) CH647778A5 (xx)
CY (1) CY1325A (xx)
DE (1) DE3141256C2 (xx)
DK (1) DK148481C (xx)
ES (2) ES501994A0 (xx)
FI (1) FI75159C (xx)
FR (1) FR2492383A1 (xx)
GB (1) GB2085436B (xx)
GR (1) GR74687B (xx)
HK (1) HK35386A (xx)
HU (2) HU187999B (xx)
IE (1) IE51646B1 (xx)
IL (1) IL64047A (xx)
IT (1) IT1143244B (xx)
KE (1) KE3596A (xx)
LU (1) LU83657A1 (xx)
MY (1) MY8600475A (xx)
NL (2) NL179055C (xx)
NZ (1) NZ196974A (xx)
OA (1) OA06920A (xx)
PT (1) PT73824B (xx)
SE (2) SE439167B (xx)
SG (1) SG97885G (xx)
SU (1) SU1342420A3 (xx)
YU (2) YU42565B (xx)
ZA (1) ZA812759B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT387221B (de) * 1980-09-08 1988-12-27 Bristol Myers Co Verfahren zur herstellung des neuen
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
JPS5945380U (ja) * 1982-09-20 1984-03-26 いすゞ自動車株式会社 車両用帯状体の固定装置
US5066783A (en) * 1986-05-20 1991-11-19 Cohen Eric A Antiviral peptides and means for treating herpes infections
US4810789A (en) * 1987-08-28 1989-03-07 Bristol-Myers Company Process for buspirone hydrochloride polymorphic crystalline form conversion
US5015646A (en) * 1987-08-28 1991-05-14 Bristol-Myers Squibb Co. Pharmaceutically useful polymorphic modification of buspirone
US5631017A (en) * 1993-03-26 1997-05-20 Beth Israel Deaconess Medical Center, Inc. Topical application of buspirone for treatment of pathological conditions associated with immune responses
US5484788A (en) * 1993-03-26 1996-01-16 Beth Israel Hospital Association Buspirone as a systemic immunosuppressant
FR2705098B1 (fr) * 1993-05-10 1995-08-04 Esteve Labor Dr Procédé de préparation de 2-{4-[4-(chloro-1-pyrazolyl)butyl]1-pipérazinyl}pyrimidine (Lesopitron) .
US5521313A (en) * 1994-05-05 1996-05-28 Bristol-Myers Squibb Company Process for preparing certain azapirones
CA2146593A1 (en) * 1994-05-05 1995-11-06 Jack Melton Large-scale process for azapirone synthesis
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
AR038368A1 (es) * 2002-02-01 2005-01-12 Novartis Ag Compuestos n-pirimidin-2-il-aminas sustituidas como inhibidores de ige, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de un medicamento
DE06790055T1 (de) * 2005-08-30 2008-09-25 Honeywell International Inc. Verfahren zur synthese von quaternären ammoniumspirosystemen
CN101089000B (zh) * 2006-06-16 2011-01-05 北京大学 螺环哌嗪季铵盐类化合物及其制备方法和应用
CN101362751B (zh) * 2007-08-10 2011-05-11 成都科瑞德医药投资有限责任公司 枸橼酸坦度螺酮及其制备方法、制剂和质量控制方法
ES2594709T3 (es) * 2010-04-26 2016-12-22 Sumitomo Dainippon Pharma Co., Ltd. Un proceso de preparación de una sal de amonio cuaternario
EP2563791B1 (en) * 2010-04-26 2014-12-24 Sumitomo Dainippon Pharma Co., Ltd. A process of a quaternary ammonium salt using phosphate
IT201900000657A1 (it) 2019-01-16 2020-07-16 Procos Spa Processo per la sintesi di gepirone

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB948730A (en) * 1959-04-08 1964-02-05 Wellcome Found Substituted cyclopropanes and related compounds
US3968216A (en) * 1969-10-29 1976-07-06 Smith Kline & French Laboratories Limited Method of inhibiting histamine activity with guanidine compounds
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation

Also Published As

Publication number Publication date
IL64047A0 (en) 1982-01-31
ZA812759B (en) 1982-05-26
ES8206516A1 (es) 1982-08-16
JPS634828B2 (xx) 1988-02-01
NZ196974A (en) 1983-05-31
FR2492383B1 (xx) 1985-01-25
KE3596A (en) 1986-02-07
LU83657A1 (fr) 1982-04-14
SE8600174D0 (sv) 1986-01-15
DK148481B (da) 1985-07-15
CA1175832A (en) 1984-10-09
SG97885G (en) 1986-07-25
YU43316B (en) 1989-06-30
HU185967B (en) 1985-04-28
GR74687B (xx) 1984-07-03
DK148481C (da) 1985-12-16
IE51646B1 (en) 1987-01-21
IL64047A (en) 1984-12-31
GB2085436A (en) 1982-04-28
FR2492383A1 (fr) 1982-04-23
DE3141256C2 (de) 1986-06-05
SE447257B (sv) 1986-11-03
FI813178L (fi) 1982-04-17
SE8600174L (sv) 1986-01-15
US4351939A (en) 1982-09-28
KR870000321B1 (en) 1987-02-27
MY8600475A (en) 1986-12-31
ES8304967A1 (es) 1983-03-16
ES501994A0 (es) 1982-08-16
FI75159C (fi) 1988-05-09
PT73824B (en) 1983-10-31
AU7029281A (en) 1982-04-22
SE8106060L (sv) 1982-04-17
YU110381A (en) 1983-12-31
OA06920A (fr) 1983-05-31
NL179055C (nl) 1986-07-01
BE890509A (fr) 1982-03-25
SU1342420A3 (ru) 1987-09-30
CH647778A5 (de) 1985-02-15
CY1325A (en) 1986-06-27
KR890000465B1 (ko) 1989-03-18
GB2085436B (en) 1984-01-18
JPS6153353B2 (xx) 1986-11-17
KR830007659A (ko) 1983-11-04
ES511079A0 (es) 1983-03-16
DK433781A (da) 1982-04-17
DE3141256A1 (de) 1982-08-19
PT73824A (en) 1981-11-01
SE439167B (sv) 1985-06-03
AU524822B2 (en) 1982-10-07
NL8501430A (nl) 1985-09-02
HK35386A (en) 1986-05-30
IE812420L (en) 1982-04-16
IT1143244B (it) 1986-10-22
NL179055B (nl) 1986-02-03
AT382153B (de) 1987-01-26
YU136083A (en) 1986-02-28
JPS5724384A (en) 1982-02-08
JPS61178983A (ja) 1986-08-11
ATA444681A (de) 1986-06-15
FI75159B (fi) 1988-01-29
HU187999B (en) 1986-03-28
IT8149476A0 (it) 1981-10-13
NL8104660A (nl) 1982-05-17

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