GB2059420B - 2-acetoxymethyl-2a-methyl-(5r)penam-3a-carboxylic acid 1.1-dioxide and its esters - Google Patents
2-acetoxymethyl-2a-methyl-(5r)penam-3a-carboxylic acid 1.1-dioxide and its estersInfo
- Publication number
- GB2059420B GB2059420B GB8030639A GB8030639A GB2059420B GB 2059420 B GB2059420 B GB 2059420B GB 8030639 A GB8030639 A GB 8030639A GB 8030639 A GB8030639 A GB 8030639A GB 2059420 B GB2059420 B GB 2059420B
- Authority
- GB
- United Kingdom
- Prior art keywords
- penam
- acetoxymethyl
- esters
- dioxide
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 2-acetoxymethyl-2a-methyl-(5r)penam-3a-carboxylic acid 1.1-dioxide Chemical compound 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
- C07D499/32—Esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/079,127 US4256733A (en) | 1979-09-26 | 1979-09-26 | Acetoxymethyl penam compounds as β-lactamase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2059420A GB2059420A (en) | 1981-04-23 |
| GB2059420B true GB2059420B (en) | 1984-03-14 |
Family
ID=22148609
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8030639A Expired GB2059420B (en) | 1979-09-26 | 1980-09-23 | 2-acetoxymethyl-2a-methyl-(5r)penam-3a-carboxylic acid 1.1-dioxide and its esters |
| GB08319784A Expired GB2125037B (en) | 1979-09-26 | 1983-07-22 | 2-acetoxymethyl-penam compounds |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB08319784A Expired GB2125037B (en) | 1979-09-26 | 1983-07-22 | 2-acetoxymethyl-penam compounds |
Country Status (36)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4364957A (en) * | 1979-09-26 | 1982-12-21 | Pfizer Inc. | Bis-esters of alkanediols as antibacterial agents |
| US4511512A (en) * | 1980-05-01 | 1985-04-16 | Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Produktionsaktiensel skab) | Substantially pure dicyclohexyl ammonium 6-β-bromo-penicillanate |
| US4474698A (en) * | 1980-12-11 | 1984-10-02 | Pfizer Inc. | Process for preparing esters of penicillanic acid sulfone |
| US4361513A (en) * | 1980-12-11 | 1982-11-30 | Pfizer Inc. | Esters of penicillanic acid sulfone |
| US4558042A (en) * | 1981-05-06 | 1985-12-10 | Farmitalia Carlo Erba S.P.A. | β-Lactam-containing antibacterial agents and β-lactamase inhibitors |
| ZA826687B (en) * | 1981-09-14 | 1983-07-27 | Pfizer | Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl 5(r)penam-3-alpha-carboxylic acid 1,1-dioxides and intermediates therefor |
| JPS58185589A (ja) * | 1982-04-23 | 1983-10-29 | Taiho Yakuhin Kogyo Kk | ペニシリン誘導体 |
| JPS62198687A (ja) * | 1986-02-27 | 1987-09-02 | Taiho Yakuhin Kogyo Kk | ２β−置換チオメチルペニシリン誘導体 |
| US4861768A (en) * | 1986-02-27 | 1989-08-29 | Taiho Pharmaceutical Company, Limited | 2 β-substituted thiomethylpenicillin derivatives and their preparation and use |
| WO1993012250A1 (en) * | 1991-12-19 | 1993-06-24 | Novo Nordisk A/S | AN IMPROVED METHOD FOR THE PREPARATION OF CERTAIN β-LACTAM ANTIBIOTICS |
| CN115385934A (zh) * | 2022-10-26 | 2022-11-25 | 北京纳百生物科技有限公司 | 一种舒巴坦半抗原及其合成方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE648188A (enExample) | 1963-05-29 | 1964-09-16 | ||
| IN149747B (enExample) | 1977-06-07 | 1982-04-03 | Pfizer |
-
1979
- 1979-09-26 US US06/079,127 patent/US4256733A/en not_active Expired - Lifetime
-
1980
- 1980-08-13 SE SE8005714A patent/SE449865B/sv not_active IP Right Cessation
- 1980-08-20 IN IN607/DEL/80A patent/IN154557B/en unknown
- 1980-08-20 ZA ZA00805132A patent/ZA805132B/xx unknown
- 1980-09-19 HU HU802310A patent/HU183212B/hu unknown
- 1980-09-19 SU SU802983144A patent/SU959628A3/ru active
- 1980-09-22 CS CS806403A patent/CS212284B2/cs unknown
- 1980-09-22 PL PL1980226868A patent/PL126949B1/pl unknown
- 1980-09-23 GR GR62939A patent/GR70065B/el unknown
- 1980-09-23 EG EG584/80A patent/EG14888A/xx active
- 1980-09-23 GB GB8030639A patent/GB2059420B/en not_active Expired
- 1980-09-23 IL IL61117A patent/IL61117A/xx unknown
- 1980-09-23 CA CA000360886A patent/CA1150242A/en not_active Expired
- 1980-09-23 AT AT0474680A patent/AT366384B/de not_active IP Right Cessation
- 1980-09-24 KR KR1019800003721A patent/KR840000796B1/ko not_active Expired
- 1980-09-24 PH PH24617A patent/PH15697A/en unknown
- 1980-09-24 AR AR282629A patent/AR224547A1/es active
- 1980-09-24 MX MX809044U patent/MX6580E/es unknown
- 1980-09-24 DE DE3035995A patent/DE3035995C2/de not_active Expired
- 1980-09-24 LU LU82795A patent/LU82795A1/fr unknown
- 1980-09-25 DK DK404980A patent/DK404980A/da not_active Application Discontinuation
- 1980-09-25 NL NLAANVRAGE8005344,A patent/NL185923C/xx not_active IP Right Cessation
- 1980-09-25 DD DD80224128A patent/DD153123A5/de unknown
- 1980-09-25 FR FR8020618A patent/FR2465736A1/fr active Granted
- 1980-09-25 YU YU2449/80A patent/YU41733B/xx unknown
- 1980-09-25 FI FI803028A patent/FI67552C/fi not_active IP Right Cessation
- 1980-09-25 NZ NZ195058A patent/NZ195058A/xx unknown
- 1980-09-25 BE BE0/202222A patent/BE885389A/fr not_active IP Right Cessation
- 1980-09-25 IE IE1998/80A patent/IE50506B1/en not_active IP Right Cessation
- 1980-09-25 AU AU62713/80A patent/AU517074B2/en not_active Ceased
- 1980-09-25 IE IE1095/85A patent/IE50507B1/en unknown
- 1980-09-25 CH CH719980A patent/CH645646A5/fr not_active IP Right Cessation
- 1980-09-25 NO NO802836A patent/NO160370C/no unknown
- 1980-09-25 IT IT24920/80A patent/IT1132754B/it active
- 1980-09-25 JP JP55133639A patent/JPS6016958B2/ja not_active Expired
- 1980-09-25 PT PT71837A patent/PT71837B/pt unknown
- 1980-09-25 ES ES495354A patent/ES495354A0/es active Granted
-
1983
- 1983-03-25 NO NO83831082A patent/NO160299C/no unknown
- 1983-07-22 GB GB08319784A patent/GB2125037B/en not_active Expired
-
1984
- 1984-01-30 FI FI840367A patent/FI67854C/fi not_active IP Right Cessation
-
1985
- 1985-02-27 SE SE8500965A patent/SE461528B/sv not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19930923 |