GB1548856A - Process for hypotensive 2-(4-substituted piperazin 1-yl)-j-aminopainazolines - Google Patents

Process for hypotensive 2-(4-substituted piperazin 1-yl)-j-aminopainazolines

Info

Publication number
GB1548856A
GB1548856A GB24841/77A GB2484177A GB1548856A GB 1548856 A GB1548856 A GB 1548856A GB 24841/77 A GB24841/77 A GB 24841/77A GB 2484177 A GB2484177 A GB 2484177A GB 1548856 A GB1548856 A GB 1548856A
Authority
GB
United Kingdom
Prior art keywords
dimethoxyquinazoline
compounds
carbon atoms
amino group
aminopainazolines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB24841/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of GB1548856A publication Critical patent/GB1548856A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB24841/77A 1976-06-15 1977-06-14 Process for hypotensive 2-(4-substituted piperazin 1-yl)-j-aminopainazolines Expired GB1548856A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69620176A 1976-06-15 1976-06-15

Publications (1)

Publication Number Publication Date
GB1548856A true GB1548856A (en) 1979-07-18

Family

ID=24796111

Family Applications (1)

Application Number Title Priority Date Filing Date
GB24841/77A Expired GB1548856A (en) 1976-06-15 1977-06-14 Process for hypotensive 2-(4-substituted piperazin 1-yl)-j-aminopainazolines

Country Status (34)

Country Link
JP (1) JPS52153985A (fr)
AR (1) AR218251A1 (fr)
AT (1) AT356115B (fr)
BE (1) BE855656A (fr)
BG (3) BG35594A3 (fr)
CA (1) CA1068698A (fr)
CH (3) CH638203A5 (fr)
CS (1) CS202069B2 (fr)
DD (1) DD131021A5 (fr)
DE (1) DE2725019A1 (fr)
DK (1) DK146625C (fr)
EG (1) EG12922A (fr)
ES (1) ES459364A1 (fr)
FI (1) FI66853C (fr)
FR (1) FR2355015A1 (fr)
GB (1) GB1548856A (fr)
GR (1) GR72288B (fr)
HK (1) HK31481A (fr)
HU (1) HU177883B (fr)
IE (1) IE45423B1 (fr)
IL (1) IL52167A (fr)
LU (1) LU77530A1 (fr)
MY (1) MY8100270A (fr)
NL (1) NL172543C (fr)
NO (1) NO147838C (fr)
NZ (1) NZ184168A (fr)
PH (1) PH22196A (fr)
PL (3) PL105558B1 (fr)
PT (1) PT66617B (fr)
RO (3) RO77330A (fr)
SE (2) SE435380B (fr)
SU (2) SU1033002A3 (fr)
YU (1) YU40164B (fr)
ZA (1) ZA773014B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6084095A (en) * 1994-01-25 2000-07-04 Warner-Lambert Company Substituted pyrido[3,2-d]pyrimidines capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
EP1018879A1 (fr) * 1996-02-02 2000-07-19 Nitromed, Inc. Composes d'antagonistes nitroses ou nitrosyles du recepteur alpha-adrenergique, leurs compositions et utilisations
US6596726B1 (en) 1994-01-25 2003-07-22 Warner Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346675A1 (de) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
AT384218B (de) * 1985-12-04 1987-10-12 Gerot Pharmazeutika Verfahren zur herstellung von neuen chinazolin-derivaten
CA2077252C (fr) * 1992-08-31 2001-04-10 Khashayar Karimian Methodes de fabrication d'urees et de guanidines et composes intermediaires servant a ces syntheses
US5654307A (en) * 1994-01-25 1997-08-05 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
JPS536156B2 (fr) * 1972-10-30 1978-03-04
US3935213A (en) 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (fr) * 1974-03-25 1975-10-04

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6084095A (en) * 1994-01-25 2000-07-04 Warner-Lambert Company Substituted pyrido[3,2-d]pyrimidines capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
US6265410B1 (en) 1994-01-25 2001-07-24 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
US6455534B2 (en) 1994-01-25 2002-09-24 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
US6521620B1 (en) 1994-01-25 2003-02-18 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
US6596726B1 (en) 1994-01-25 2003-07-22 Warner Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
US6713484B2 (en) 1994-01-25 2004-03-30 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
EP1018879A1 (fr) * 1996-02-02 2000-07-19 Nitromed, Inc. Composes d'antagonistes nitroses ou nitrosyles du recepteur alpha-adrenergique, leurs compositions et utilisations
EP1018879A4 (fr) * 1996-02-02 2002-07-24 Nitromed Inc Composes d'antagonistes nitroses ou nitrosyles du recepteur alpha-adrenergique, leurs compositions et utilisations

Also Published As

Publication number Publication date
NL172543B (nl) 1983-04-18
SE7705745L (sv) 1977-12-16
SE450120B (sv) 1987-06-09
RO77308A (fr) 1981-08-17
FI771741A (fr) 1977-12-16
NO147838C (no) 1983-06-22
RO73050A (fr) 1981-08-30
ES459364A1 (es) 1978-03-16
AT356115B (de) 1980-04-10
IL52167A (en) 1981-01-30
DK146625B (da) 1983-11-21
RO77330A (fr) 1981-06-22
FR2355015B1 (fr) 1981-07-24
FR2355015A1 (fr) 1978-01-13
IE45423B1 (en) 1982-08-25
FI66853B (fi) 1984-08-31
CA1068698A (fr) 1979-12-25
BG35594A3 (en) 1984-05-15
NL172543C (nl) 1983-09-16
ATA386977A (de) 1979-09-15
NO771919L (no) 1977-12-16
DE2725019A1 (de) 1977-12-22
BG35748A3 (en) 1984-06-15
BE855656A (fr) 1977-12-14
BG35747A3 (en) 1984-06-15
JPS5543465B2 (fr) 1980-11-06
IL52167A0 (en) 1977-07-31
NO147838B (no) 1983-03-14
IE45423L (en) 1977-12-15
PH22196A (en) 1988-06-28
HU177883B (en) 1982-01-28
AU2558377A (en) 1978-09-07
JPS52153985A (en) 1977-12-21
SU946402A3 (ru) 1982-07-23
PL198874A1 (pl) 1978-04-10
MY8100270A (en) 1981-12-31
SE8107554L (sv) 1981-12-16
DK240877A (da) 1977-12-16
ZA773014B (en) 1978-04-26
SE435380B (sv) 1984-09-24
DD131021A5 (de) 1978-05-24
CH638516A5 (en) 1983-09-30
NL7705939A (nl) 1977-12-19
FI66853C (fi) 1984-12-10
AR218251A1 (es) 1980-05-30
SU1033002A3 (ru) 1983-07-30
PL113012B1 (en) 1980-11-29
DK146625C (da) 1984-06-04
LU77530A1 (fr) 1979-03-26
EG12922A (en) 1980-03-31
PT66617A (en) 1977-06-01
PT66617B (en) 1978-10-27
PL111221B1 (en) 1980-08-30
CH638203A5 (en) 1983-09-15
YU132677A (en) 1982-08-31
CH638517A5 (en) 1983-09-30
YU40164B (en) 1985-08-31
HK31481A (en) 1981-07-10
GR72288B (fr) 1983-10-17
NZ184168A (en) 1979-08-31
CS202069B2 (en) 1980-12-31
PL105558B1 (pl) 1979-10-31

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940614