FR2741537B1 - Compositions pharmaceutiques comprenant un hydroxyacide gras polyethoxyle sature - Google Patents

Compositions pharmaceutiques comprenant un hydroxyacide gras polyethoxyle sature

Info

Publication number
FR2741537B1
FR2741537B1 FR9614708A FR9614708A FR2741537B1 FR 2741537 B1 FR2741537 B1 FR 2741537B1 FR 9614708 A FR9614708 A FR 9614708A FR 9614708 A FR9614708 A FR 9614708A FR 2741537 B1 FR2741537 B1 FR 2741537B1
Authority
FR
France
Prior art keywords
polyethoxyl
hydroxyacid
fat
saturated
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9614708A
Other languages
English (en)
Other versions
FR2741537A1 (fr
Inventor
Klaus Neuer
Monika Petszulat
Hatto Walch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2741537A1 publication Critical patent/FR2741537A1/fr
Application granted granted Critical
Publication of FR2741537B1 publication Critical patent/FR2741537B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9614708A 1995-11-29 1996-11-29 Compositions pharmaceutiques comprenant un hydroxyacide gras polyethoxyle sature Expired - Fee Related FR2741537B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19544507A DE19544507B4 (de) 1995-11-29 1995-11-29 Cyclosporin enthaltende Präparate

Publications (2)

Publication Number Publication Date
FR2741537A1 FR2741537A1 (fr) 1997-05-30
FR2741537B1 true FR2741537B1 (fr) 2000-10-13

Family

ID=7778716

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9614708A Expired - Fee Related FR2741537B1 (fr) 1995-11-29 1996-11-29 Compositions pharmaceutiques comprenant un hydroxyacide gras polyethoxyle sature

Country Status (25)

Country Link
US (1) US6951841B2 (fr)
EP (3) EP1074263B1 (fr)
JP (2) JP3363907B2 (fr)
KR (2) KR100593701B1 (fr)
CN (2) CN1133460C (fr)
AR (1) AR012287A1 (fr)
AT (2) ATE315401T1 (fr)
AU (1) AU1139097A (fr)
BE (1) BE1010112A4 (fr)
BR (1) BR9611802A (fr)
CA (1) CA2238944A1 (fr)
CO (1) CO4761073A1 (fr)
CZ (1) CZ294260B6 (fr)
DE (4) DE19544507B4 (fr)
DK (2) DK1074263T3 (fr)
ES (2) ES2254091T3 (fr)
FR (1) FR2741537B1 (fr)
HK (1) HK1010830A1 (fr)
IT (1) IT1288395B1 (fr)
PE (1) PE22598A1 (fr)
PT (1) PT863765E (fr)
SK (2) SK286613B6 (fr)
TW (1) TW404837B (fr)
WO (1) WO1997019692A1 (fr)
ZA (1) ZA9610070B (fr)

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CN101502641B (zh) * 2009-02-23 2012-05-02 姚定全 一种注射给药的环孢素药物组合物
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RU2158601C2 (ru) * 1994-11-03 2000-11-10 Новартис Аг Новые лекарственные формы циклоспорина для орального применения с простым составом и высокой биодоступностью и способ их получения

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US20010003589A1 (en) 2001-06-14
CN1496742A (zh) 2004-05-19
JP2002338492A (ja) 2002-11-27
JP3363907B2 (ja) 2003-01-08
AU1139097A (en) 1997-06-19
DE19544507B4 (de) 2007-11-15
ITRM960810A1 (it) 1998-05-27
TW404837B (en) 2000-09-11
KR19990071581A (ko) 1999-09-27
JPH11511484A (ja) 1999-10-05
IT1288395B1 (it) 1998-09-22
CN1204261A (zh) 1999-01-06
EP1074263A3 (fr) 2001-04-11
PT863765E (pt) 2004-06-30
HK1010830A1 (en) 1999-07-02
KR100593701B1 (ko) 2007-04-25
EP0863765A1 (fr) 1998-09-16
DE69635720T2 (de) 2006-08-10
SK286613B6 (sk) 2009-02-05
DE19549852B4 (de) 2009-06-04
ZA9610070B (en) 1998-05-29
EP1074263B1 (fr) 2006-01-11
JP3831676B2 (ja) 2006-10-11
EP0863765B1 (fr) 2004-02-18
BR9611802A (pt) 1999-09-21
ITRM960810A0 (it) 1996-11-27
BE1010112A4 (fr) 1997-12-02
CZ294260B6 (cs) 2004-11-10
DK0863765T3 (da) 2004-06-01
DE69631601D1 (de) 2004-03-25
DE69635720D1 (de) 2006-04-06
CN1246035C (zh) 2006-03-22
DE19544507A1 (de) 1997-06-05
ES2254091T3 (es) 2006-06-16
CZ163198A3 (cs) 1998-08-12
PE22598A1 (es) 1998-05-11
KR100864618B1 (ko) 2008-10-22
US6951841B2 (en) 2005-10-04
CA2238944A1 (fr) 1997-06-05
SK71798A3 (en) 1998-11-04
EP1074263A2 (fr) 2001-02-07
KR20040094679A (ko) 2004-11-10
DK1074263T3 (da) 2006-03-06
CN1133460C (zh) 2004-01-07
EP1604650A2 (fr) 2005-12-14
SK284460B6 (sk) 2005-04-01
EP1604650A3 (fr) 2008-04-02
CO4761073A1 (es) 1999-04-27
FR2741537A1 (fr) 1997-05-30
ATE259649T1 (de) 2004-03-15
ES2216076T3 (es) 2004-10-16
WO1997019692A1 (fr) 1997-06-05
ATE315401T1 (de) 2006-02-15
AR012287A1 (es) 2000-10-18
DE69631601T2 (de) 2004-12-16

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