FR2456105A1 - Procede pour la preparation de tetrahydro-pyrrolo (1,2-a) pyrimidines substituees en position 3, compositions pharmaceutiques contenant ces composes et nouvelles tetrahydro-pyrrolo (1,2-a) pyrimidines substituees en position 3 - Google Patents

Procede pour la preparation de tetrahydro-pyrrolo (1,2-a) pyrimidines substituees en position 3, compositions pharmaceutiques contenant ces composes et nouvelles tetrahydro-pyrrolo (1,2-a) pyrimidines substituees en position 3

Info

Publication number
FR2456105A1
FR2456105A1 FR8010477A FR8010477A FR2456105A1 FR 2456105 A1 FR2456105 A1 FR 2456105A1 FR 8010477 A FR8010477 A FR 8010477A FR 8010477 A FR8010477 A FR 8010477A FR 2456105 A1 FR2456105 A1 FR 2456105A1
Authority
FR
France
Prior art keywords
pyrrolo
tetrahydro
pyrimidines substituted
compounds
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8010477A
Other languages
English (en)
Other versions
FR2456105B1 (fr
Inventor
Jozsef Kokosi
Istvan Hermecz
Zoltan Meszaros
Gyorgy Szasz
Lelle Vasvari
Agnes Horvath
Tibor Breining
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of FR2456105A1 publication Critical patent/FR2456105A1/fr
Application granted granted Critical
Publication of FR2456105B1 publication Critical patent/FR2456105B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'INVENTION CONCERNE DES DERIVES DE FORMULE GENERALE: (CF DESSIN DANS BOPI) ET (CF DESSIN DANS BOPI) AINSI QU'UN MELANGE DE TELS COMPOSES ET LEURS SELS D'ADDITION D'ACIDE ET SELS QUATERNAIRES PHARMACEUTIQUEMENT ACCEPTABLES, OU: R REPRESENTE DE L'HYDROGENE OU UN GROUPE ALCOYLE INFERIEUR. R REPRESENTE UN GROUPE ALCOYLE INFERIEUR, PHENYLE, CARBOXYLE, (ALCOXY INFERIEUR) CARBONYLE, NITRILE, CARBAMOYLE OU CARBOHYDRAZIDO. R REPRESENTE DE L'HYDROGENE OU UN GROUPE ALCOYLE INFERIEUR, AVEC LA CONDITION QUE SI, DANS LA FORMULE I, R REPRESENTE DE L'HYDROGENE, ALORS R NE PEUT PAS ETRE UN GROUPE NITRILE, ALCOXY-CARBONYLE OU PROPYLE. APPLICATION COMME MEDICAMENTS.
FR8010477A 1979-05-11 1980-05-09 Procede pour la preparation de tetrahydro-pyrrolo (1,2-a) pyrimidines substituees en position 3, compositions pharmaceutiques contenant ces composes et nouvelles tetrahydro-pyrrolo (1,2-a) pyrimidines substituees en position 3 Granted FR2456105A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1930A HU176942B (hu) 1979-05-11 1979-05-11 Sposob poluchenija 2,3- i 3,4-dvuzamehhjonnykh tetragidro-pirrolo!1,2-a!-pirimidinov

Publications (2)

Publication Number Publication Date
FR2456105A1 true FR2456105A1 (fr) 1980-12-05
FR2456105B1 FR2456105B1 (fr) 1984-08-10

Family

ID=10994745

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8010477A Granted FR2456105A1 (fr) 1979-05-11 1980-05-09 Procede pour la preparation de tetrahydro-pyrrolo (1,2-a) pyrimidines substituees en position 3, compositions pharmaceutiques contenant ces composes et nouvelles tetrahydro-pyrrolo (1,2-a) pyrimidines substituees en position 3

Country Status (27)

Country Link
US (1) US4367229A (fr)
JP (1) JPS565479A (fr)
AR (1) AR225308A1 (fr)
AU (1) AU539466B2 (fr)
BE (1) BE883215A (fr)
CA (1) CA1149806A (fr)
CH (1) CH649551A5 (fr)
CS (1) CS221550B2 (fr)
DD (1) DD150612A5 (fr)
DE (1) DE3017625A1 (fr)
DK (1) DK152501C (fr)
ES (1) ES491153A0 (fr)
FI (1) FI70218C (fr)
FR (1) FR2456105A1 (fr)
GB (1) GB2049694B (fr)
GR (1) GR68516B (fr)
HU (1) HU176942B (fr)
IL (1) IL59987A (fr)
IT (1) IT1147735B (fr)
LU (1) LU82435A1 (fr)
NL (1) NL8002682A (fr)
NO (1) NO155773C (fr)
PL (1) PL123709B1 (fr)
PT (1) PT71211A (fr)
SE (1) SE437030B (fr)
SU (1) SU1048986A3 (fr)
YU (1) YU122080A (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4482557A (en) * 1979-05-11 1984-11-13 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 3-Substituted-2-oxo-tetrahydro-pyrrol[1,2-a]pyrimidines having digitalis-like activity
CA1211111A (fr) * 1982-02-15 1986-09-09 Isao Yanagisawa Methode de preparation de composes nouveau genre de pyrimidone
US5344933A (en) * 1991-09-11 1994-09-06 Fuji Photo Film Co., Ltd. Pyrrole ring-or condensed pyrrole ring-containing azomethine dye
CN1138777C (zh) * 1997-01-22 2004-02-18 西巴特殊化学品控股有限公司 基于α-氨基酮的可光活化的含氮碱
JP2000026465A (ja) * 1998-07-14 2000-01-25 Fuji Photo Film Co Ltd ピロロ［１，２−ａ］ピリミジン化合物及びそれを用いた感熱記録材料
US11983498B2 (en) * 2021-03-18 2024-05-14 Augmented Intelligence Technologies, Inc. System and methods for language processing of document sequences using a neural network

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2154482A1 (fr) * 1971-09-10 1973-05-11 Takeda Chemical Industries Ltd

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1803758U (de) 1959-09-03 1960-01-07 Eugen Haller Spritz- und spanschutz -geraet.
AT286990B (de) * 1966-11-02 1971-01-11 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
DE1803785A1 (de) * 1968-10-18 1970-06-04 Hoechst Ag Verfahren zur Herstellung von 1,2-disubstituierten 6-Oxo-1.4.5.6-tetrahydropyrimidinen
HU167676B (fr) 1972-11-29 1975-11-28
US4209622A (en) * 1973-03-30 1980-06-24 Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt. 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2154482A1 (fr) * 1971-09-10 1973-05-11 Takeda Chemical Industries Ltd

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
COMPTES RENDUS DE LÖACADEMIE DES SCIENCES DE PARIS, série C, vol. 262, 24 janvier 1966 A. ETIENNE et al. "Synthèse de pyrrolopyrimidones à partir de l'amino-2-pyrroline-I" pages 365-368 *

Also Published As

Publication number Publication date
NL8002682A (nl) 1980-11-13
CA1149806A (fr) 1983-07-12
IT1147735B (it) 1986-11-26
PL123709B1 (en) 1982-11-30
NO155773B (no) 1987-02-16
DK152501B (da) 1988-03-07
SE437030B (sv) 1985-02-04
US4367229A (en) 1983-01-04
ES8104293A1 (es) 1981-04-16
DK204880A (da) 1980-11-12
FI70218B (fi) 1986-02-28
SE8003477L (sv) 1980-11-12
CS221550B2 (en) 1983-04-29
DK152501C (da) 1988-08-08
DD150612A5 (de) 1981-09-09
AU539466B2 (en) 1984-09-27
DE3017625A1 (de) 1980-11-20
YU122080A (en) 1983-02-28
BE883215A (fr) 1980-09-01
AU5827680A (en) 1980-11-13
FR2456105B1 (fr) 1984-08-10
NO801376L (no) 1980-11-12
GB2049694B (en) 1983-05-18
NO155773C (no) 1987-05-27
PT71211A (en) 1980-06-01
LU82435A1 (de) 1980-07-31
ES491153A0 (es) 1981-04-16
IT8067738A0 (it) 1980-05-09
HU176942B (hu) 1981-06-28
IL59987A (en) 1984-04-30
PL224124A1 (fr) 1981-02-13
AR225308A1 (es) 1982-03-15
IL59987A0 (en) 1980-07-31
SU1048986A3 (ru) 1983-10-15
GR68516B (fr) 1982-01-11
FI70218C (fi) 1986-09-15
CH649551A5 (de) 1985-05-31
FI801515A (fi) 1980-11-12
JPS565479A (en) 1981-01-20
GB2049694A (en) 1980-12-31

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