FR2456744A1 - Derives de la pyrazolo (1,5-c)quinazoline, procede de preparation de ces derives et medicaments contenant ces derniers - Google Patents

Derives de la pyrazolo (1,5-c)quinazoline, procede de preparation de ces derives et medicaments contenant ces derniers

Info

Publication number
FR2456744A1
FR2456744A1 FR8010562A FR8010562A FR2456744A1 FR 2456744 A1 FR2456744 A1 FR 2456744A1 FR 8010562 A FR8010562 A FR 8010562A FR 8010562 A FR8010562 A FR 8010562A FR 2456744 A1 FR2456744 A1 FR 2456744A1
Authority
FR
France
Prior art keywords
pyrazolo
preparation
same
quinazoline derivatives
medicaments containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8010562A
Other languages
English (en)
Other versions
FR2456744B1 (fr
Inventor
Edit Berenyi
Eniko Szirt
Peter Gorog
Lujza Petocz
Ibolya Kosoczky
Agnes Kovacs
Et Gabriella Urmos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FR2456744A1 publication Critical patent/FR2456744A1/fr
Application granted granted Critical
Publication of FR2456744B1 publication Critical patent/FR2456744B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENTION EST RELATIVE A DES NOUVEAUX DERIVES DE LA PYRAZOLO1,5-C QUINAZOLINE ET A LEUR PROCEDE DE PREPARATION. CES PRODUITS CORRESPONDENT A LA FORMULE GENERALE I CI-APRES: (CF DESSIN DANS BOPI) DANS LAQUELLE: R, R, R ET R SONT TELS QUE DEFINIS DANS LE BREVET. APPLICATION EN TANT QUE MEDICAMENTS, ET NOTAMMENT EN TANT QU'AGENTS ANALGESIQUES.
FR8010562A 1979-05-18 1980-05-12 Derives de la pyrazolo (1,5-c)quinazoline, procede de preparation de ces derives et medicaments contenant ces derniers Granted FR2456744A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79EE2663A HU178523B (en) 1979-05-18 1979-05-18 Process for preparing new pyrazolo-quinazoline derivatives

Publications (2)

Publication Number Publication Date
FR2456744A1 true FR2456744A1 (fr) 1980-12-12
FR2456744B1 FR2456744B1 (fr) 1983-06-17

Family

ID=10995850

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8010562A Granted FR2456744A1 (fr) 1979-05-18 1980-05-12 Derives de la pyrazolo (1,5-c)quinazoline, procede de preparation de ces derives et medicaments contenant ces derniers

Country Status (17)

Country Link
US (1) US4303660A (fr)
JP (1) JPS55154974A (fr)
AT (1) AT375941B (fr)
AU (1) AU528013B2 (fr)
BE (1) BE883204A (fr)
CH (1) CH646170A5 (fr)
CS (1) CS241026B2 (fr)
DD (1) DD150897A5 (fr)
DE (1) DE3019019A1 (fr)
ES (1) ES491608A0 (fr)
FR (1) FR2456744A1 (fr)
GB (1) GB2051054B (fr)
GR (1) GR68462B (fr)
HU (1) HU178523B (fr)
IT (1) IT1149882B (fr)
NL (1) NL8002853A (fr)
SU (3) SU978731A3 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469868A (en) * 1982-05-24 1984-09-04 Warner-Lambert Company Alkylimidazo[1,2-c]pyrazolo[3,4-e]pyrimidines
DE3942357A1 (de) * 1989-12-21 1991-06-27 Boehringer Mannheim Gmbh 3-aminopyrazolo-heterocyclen, deren verwendung zur bestimmung von wasserstoffperoxid, wasserstoffperoxid-bildenden systemen, peroxidase, peroxidatisch wirksamen substanzen oder von elektronenreichen aromatischen verbindungen, entsprechende bestimmungsverfahren und hierfuer geeignete mittel
CA2360934A1 (fr) * 1999-02-22 2000-08-31 Lin-Hua Zhang Derives polycyclo heterocycliques utilises en tant qu'agents anti-inflammatoires
GB2454549B (en) * 2007-09-25 2009-09-23 Medical & Pharm Ind Tech & Dev Uses of 2-[piperidinyl]methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one for providing an anti-allergic effect and histamine H1 receptor antagonism effect
CN103130810B (zh) * 2013-03-11 2015-02-25 河南师范大学 一种吡唑并[1,5-c]喹唑啉类化合物的合成方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313815A (en) * 1964-05-04 1967-04-11 Sterling Drug Inc 8-chloropyrazolo-[1, 5-c]quinazoline derivatives and methods of preparing same
US4110452A (en) * 1977-10-17 1978-08-29 E. R. Squibb & Sons, Inc. Pyrazolo (1,5-c) quinazoline derivatives and related compounds
US4112098A (en) * 1977-10-17 1978-09-05 E. R. Squibb & Sons, Inc. Pyrazolo[1,5-c]quinazoline derivatives and related compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3531482A (en) * 1966-10-13 1970-09-29 Sandoz Ag Pyrazolo(1,5-c)quinazolines
US3897434A (en) * 1974-04-12 1975-07-29 Lilly Co Eli Pyrazolo{8 1,5-c{9 quinazolin-5(6H)-ones
US4076818A (en) * 1976-07-02 1978-02-28 E. R. Squibb & Sons, Inc. Pyrazolo [1,5-C]quinazoline derivatives and related compounds
US4198412A (en) * 1978-12-13 1980-04-15 E. R. Squibb & Sons, Inc. Pyrazolo [1,5-C] quinazoline derivatives and their use in treating allergic conditions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313815A (en) * 1964-05-04 1967-04-11 Sterling Drug Inc 8-chloropyrazolo-[1, 5-c]quinazoline derivatives and methods of preparing same
US4110452A (en) * 1977-10-17 1978-08-29 E. R. Squibb & Sons, Inc. Pyrazolo (1,5-c) quinazoline derivatives and related compounds
US4112098A (en) * 1977-10-17 1978-09-05 E. R. Squibb & Sons, Inc. Pyrazolo[1,5-c]quinazoline derivatives and related compounds

Also Published As

Publication number Publication date
ES8105319A1 (es) 1981-05-16
SU978731A3 (ru) 1982-11-30
AT375941B (de) 1984-09-25
AU5848580A (en) 1980-11-20
DE3019019C2 (fr) 1988-12-01
US4303660A (en) 1981-12-01
DD150897A5 (de) 1981-09-23
GR68462B (fr) 1981-12-30
SU1017171A3 (ru) 1983-05-07
CS241026B2 (en) 1986-03-13
AU528013B2 (en) 1983-03-31
DE3019019A1 (de) 1980-11-27
CS340780A2 (en) 1985-06-13
IT1149882B (it) 1986-12-10
HU178523B (en) 1982-05-28
CH646170A5 (de) 1984-11-15
NL8002853A (nl) 1980-11-20
GB2051054A (en) 1981-01-14
ATA262580A (de) 1984-02-15
JPS55154974A (en) 1980-12-02
IT8022111A0 (it) 1980-05-16
SU1015828A3 (ru) 1983-04-30
ES491608A0 (es) 1981-05-16
BE883204A (fr) 1980-11-10
GB2051054B (en) 1983-05-18
JPH0227356B2 (fr) 1990-06-15
FR2456744B1 (fr) 1983-06-17

Similar Documents

Publication Publication Date Title
TNSN86117A1 (fr) Nouvelles (piperazinyl 4-substitue) pyridazines utiles notamment comme medicaments analgesiques et antitussifs, et procede pour leur preparation
ATE71375T1 (de) Substituierte 6-fluor-4-oxo-1,4-dihydrochinolin-3-carbonsaeure ; deren derivate; diese verbindung enthaltende pharmazeutische zubereitungen und verfahren zur herstellung dieser verbindungen.
FR2360587A1 (fr) Nouveaux derives d'amino-alcoyl-furannes utiles comme medicaments
FR2453158A1 (fr) Nouveaux acides benzimidazolyl-acetohydroxamiques, leur procede de preparation et leur application en therapeutique
FR2392971A1 (fr) Derives de l'acide prostanoique, leur preparation et medicament contenant ces substances
ATE60579T1 (de) Pyrrolidinamid-derivate mit antipropylendopeptidase-wirkung, zusammenstellungen, die sie enthalten, verfahren zu ihrer herstellung und heilmittel, die sie enthalten.
FR2361901A1 (fr) Derives de substitution de nucleotides et medicament contenant ces substances
NO178923C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive 24-homo-vitamin-D-derivater
FR2425433A1 (fr) Nouveaux acides lactame-n-acetiques et leurs amides, leurs procedes de preparation et compositions therapeutiques
FR2360601A1 (fr) Nouveaux derives d'acides phosphoneux, leur preparation et leur application en tant que medicaments
FR2401925A1 (fr) Nouveaux derives de la mitomycine c utiles comme medicaments et procede de leur preparation
FR2370744A1 (fr) Nouveaux derives d'aminopropanol, procede pour leur preparation et medicaments contenant ces composes
FR2453866A1 (fr) Derives peptidiques, procede pour leur preparation et leur application dans des preparations pharmaceutiques
FR2374317A1 (fr) Derives d'acide n-(benzothiazolyl-2)oxamique et procede pour leur preparation et leur utilisation comme medicament anti-allergique
FR2407928A1 (fr) Derives de quinazoline utiles comme medicaments antihypertenseurs et procede de leur preparation
FR2358415A1 (fr) Derives peptidiques, leur preparation et leur application en tant que medicaments
FR2456744A1 (fr) Derives de la pyrazolo (1,5-c)quinazoline, procede de preparation de ces derives et medicaments contenant ces derniers
FR2381048A1 (fr) Nouveaux derives de 20,21-dinoreburnamenine, un procede pour leur preparation et leur application comme medicaments
FR2390424A1 (fr) Nouveaux derives d'amides de l'acide phenylacetique substitues, leur application en tant que medicament et leur application
FR2413358A1 (fr) Nouveaux derives de 2-aminomethylphenol, utiles notamment comme agents anti-inflammatoires, et leur procede de preparation
FR2453861A1 (fr) Nouveaux derives de la benzo-as-triazine, leur procede de preparation et medicaments les contenant
FR2449688A1 (fr) Nouveaux derives de la pyrido(3,4-e)-as-triazine, procede de preparation de ces derives et medicaments les contenant
FR2370727A1 (fr) Nouveaux derives substitues de o-phenylenediamine, leur procede de preparation et medicament les contenant
FR2453855A1 (fr) Derives d'amino-isoquinoleine, leur procede de preparation et medicaments les contenant
FI891155A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten 4,5,6,7-tetrahydroisotiatsolo/4,5-c/pyridiini-johdannaisten ja niiden isomeerien ja happoadditiosuolojen valmistamiseksi

Legal Events

Date Code Title Description
ST Notification of lapse