FR2407928A1 - Derives de quinazoline utiles comme medicaments antihypertenseurs et procede de leur preparation - Google Patents

Derives de quinazoline utiles comme medicaments antihypertenseurs et procede de leur preparation

Info

Publication number
FR2407928A1
FR2407928A1 FR7831595A FR7831595A FR2407928A1 FR 2407928 A1 FR2407928 A1 FR 2407928A1 FR 7831595 A FR7831595 A FR 7831595A FR 7831595 A FR7831595 A FR 7831595A FR 2407928 A1 FR2407928 A1 FR 2407928A1
Authority
FR
France
Prior art keywords
preparation
quinazoline derivatives
medicines
antihypertense
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7831595A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Yuka Pharmaceutical Co Ltd
Original Assignee
Mitsubishi Yuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP13310577A external-priority patent/JPS5466691A/ja
Priority claimed from JP2089178A external-priority patent/JPS54125688A/ja
Application filed by Mitsubishi Yuka Pharmaceutical Co Ltd filed Critical Mitsubishi Yuka Pharmaceutical Co Ltd
Publication of FR2407928A1 publication Critical patent/FR2407928A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'INVENTION CONCERNE DE NOUVEAUX DERIVES DE QUINAZOLINE UTILES COMME ANTIHYPERTENSEURS ET UN PROCEDE DE LEUR PREPARATION. LES NOUVEAUX COMPOSES DE L'INVENTION SONT DES DERIVES DE QUINAZOLINE REPONDANT A LA FORMULE: (CF DESSIN DANS BOPI) OU LES SYMBOLES SONT DEFINIS, ET LEURS SELS D'ADDITION D'ACIDES CONVENANT EN PHARMACIE; UN PROCEDE DE LEUR PREPARATION EST EGALEMENT DECRIT. LES COMPOSES DE L'INVENTION SONT DES MEDICAMENTS UTILES NOTAMMENT COMME ANTIHYPERTENSEURS.
FR7831595A 1977-11-08 1978-11-08 Derives de quinazoline utiles comme medicaments antihypertenseurs et procede de leur preparation Withdrawn FR2407928A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13310577A JPS5466691A (en) 1977-11-08 1977-11-08 Novel quinazoline derivative and manufacture
JP2089178A JPS54125688A (en) 1978-02-27 1978-02-27 Novel quinazoline derivative*its manufacture and antihypertensive drug

Publications (1)

Publication Number Publication Date
FR2407928A1 true FR2407928A1 (fr) 1979-06-01

Family

ID=26357889

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7831595A Withdrawn FR2407928A1 (fr) 1977-11-08 1978-11-08 Derives de quinazoline utiles comme medicaments antihypertenseurs et procede de leur preparation

Country Status (8)

Country Link
US (1) US4189484A (fr)
DE (1) DE2848263A1 (fr)
DK (1) DK495578A (fr)
ES (1) ES475173A1 (fr)
FR (1) FR2407928A1 (fr)
GB (1) GB2008106A (fr)
NL (1) NL7811050A (fr)
SE (1) SE7811492L (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0022481A1 (fr) * 1979-06-21 1981-01-21 Mitsubishi Yuka Pharmaceutical Co., Ltd. Dérivés de la 5,6-alcoylènepyrimidine, procédés pour leur préparation et préparations pharmaceutiques
FR2468595B2 (fr) * 1979-10-30 1986-03-14 Synthelabo Amides d'alkylene diamines, leur preparation et leur application en therapeutique
GB2068961B (en) * 1980-02-13 1983-11-30 Sankyo Co Quinazoline derivatives
EP0060081B1 (fr) * 1981-03-05 1985-07-17 Pfizer Inc. Pipérazinoquinazolines antihypertenseurs, procédé pour leur préparation, compositions pharmaceutiques les contenant et conjugués immunogènes formés à partir de protéines et ces composés
CS236097B1 (en) * 1983-06-01 1985-05-15 Jan Koenig Acylderivatives of 2-piperazinochinazoline and method of their preparation
DE3346675A1 (de) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
JPH0647540B2 (ja) * 1985-07-16 1994-06-22 エーザイ株式会社 虚血性心疾患・不整脈治療・予防剤
WO1987002035A1 (fr) * 1985-10-04 1987-04-09 Maggioni-Winthrop S.P.A. Aminoalcools cycloaliphatiques fusionnes
EP0367888A1 (fr) * 1988-11-08 1990-05-16 ISTITUTO LUSO FARMACO D'ITALIA S.p.A. Dérivés de 1,4-benzodioxine 2,2-disubstitués ayant une action hypotensive
GB9708917D0 (en) * 1997-05-01 1997-06-25 Pfizer Ltd Compounds useful in therapy
WO2007039170A1 (fr) * 2005-09-23 2007-04-12 European Molecular Biology Laboratory (Embl) Antagonistes de l'activite de topoisomerase et leur utilisation pour inhiber des etats pathologiques
AU2013241854B2 (en) * 2012-03-28 2017-11-02 Intervet International B.V. Heteroaryl compounds with cyclic bridging unit for use in the treatment helminth infection
WO2019010180A1 (fr) * 2017-07-06 2019-01-10 Case Western Reserve University Agonistes peptidiques et à petites molécules d'epha et leurs utilisations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines

Also Published As

Publication number Publication date
DK495578A (da) 1979-05-09
NL7811050A (nl) 1979-05-10
DE2848263A1 (de) 1979-05-10
SE7811492L (sv) 1979-05-09
US4189484A (en) 1980-02-19
GB2008106A (en) 1979-05-31
ES475173A1 (es) 1979-04-16

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Legal Events

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