FR2412565A1 - Nouveaux derives de type n-acyl-2', n-alkyl-2', di-n-acyl-4,2', di-n-alkyl-4,2', n-acyl-4 n-alkyl-2' et n-alkyl-4 n-acyl-2', desoxy-2 fortimicine b - Google Patents
Nouveaux derives de type n-acyl-2', n-alkyl-2', di-n-acyl-4,2', di-n-alkyl-4,2', n-acyl-4 n-alkyl-2' et n-alkyl-4 n-acyl-2', desoxy-2 fortimicine bInfo
- Publication number
- FR2412565A1 FR2412565A1 FR7836002A FR7836002A FR2412565A1 FR 2412565 A1 FR2412565 A1 FR 2412565A1 FR 7836002 A FR7836002 A FR 7836002A FR 7836002 A FR7836002 A FR 7836002A FR 2412565 A1 FR2412565 A1 FR 2412565A1
- Authority
- FR
- France
- Prior art keywords
- acyl
- alkyl
- fortimicin
- desoxy
- type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'INVENTION CONCERNE DE NOUVEAUX DERIVES DE TYPE N-ACYL-2, N-ALKYL-2, DI-N-ACYL-4,2, DI-N-ALKYL-4,2, N-ACYL-4 N-ALKYL-2 ET N-ALKYL-4 N-ACYL-2 DESOXY-2 FORTIMICINE B. LES COMPOSES DE L'INVENTION REPONDENT A LA FORMULE: (CF DESSIN DANS BOPI) OU LES SYMBOLES R ET R SONT DEFINIS, ET LEURS SELS CONVENANT EN PHARMACIE. LES DERIVES DE FORTIMICINE DE L'INVENTION SONT DES MEDICAMENTS UTILES NOTAMMENT COMME ANTIBIOTIQUES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/863,011 US4176178A (en) | 1977-12-21 | 1977-12-21 | 2-Deoxy-2'-N-acyl and alkyl fortimicins A and B |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2412565A1 true FR2412565A1 (fr) | 1979-07-20 |
FR2412565B1 FR2412565B1 (fr) | 1982-07-09 |
Family
ID=25340010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7836002A Granted FR2412565A1 (fr) | 1977-12-21 | 1978-12-21 | Nouveaux derives de type n-acyl-2', n-alkyl-2', di-n-acyl-4,2', di-n-alkyl-4,2', n-acyl-4 n-alkyl-2' et n-alkyl-4 n-acyl-2', desoxy-2 fortimicine b |
Country Status (10)
Country | Link |
---|---|
US (1) | US4176178A (fr) |
JP (1) | JPS5488245A (fr) |
AU (1) | AU521682B2 (fr) |
CA (1) | CA1126741A (fr) |
DE (1) | DE2855094A1 (fr) |
FR (1) | FR2412565A1 (fr) |
GB (1) | GB2010823B (fr) |
GR (1) | GR65686B (fr) |
PH (1) | PH16247A (fr) |
SE (1) | SE7812828L (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4317904A (en) * | 1977-12-21 | 1982-03-02 | Abbott Laboratories | 1,2-Epiminofortimicin B |
US4319022A (en) * | 1977-12-21 | 1982-03-09 | Abbott Laboratories | 2-O-Substituted sulfonyl derivatives of fortimicin B |
US4312858A (en) * | 1978-07-13 | 1982-01-26 | Kowa Company, Ltd. | Antibiotic KA-7038 and compositions containing same |
US4330673A (en) * | 1979-03-29 | 1982-05-18 | Abbott Laboratories | Process for producing 3-O-demethylaminoglycoside and novel 3-O-demethylfortimicin derivatives |
JPS55164695A (en) * | 1979-06-09 | 1980-12-22 | Kowa Co | Novel aminoglycoside and its preparation |
US4269970A (en) * | 1979-09-26 | 1981-05-26 | Abbott Laboratories | 1,2-Carbamates of fortimicin B and derivatives |
US4275193A (en) * | 1979-09-26 | 1981-06-23 | Abbott Laboratories | 4,5-Carbamates of fortimicin B |
US4272626A (en) * | 1979-09-26 | 1981-06-09 | Abbott Laboratories | Method of producing 1-epi-2-deoxyfortimicin A and intermediates therefor |
US4250304A (en) * | 1979-09-26 | 1981-02-10 | Abbott Laboratories | 2-Deoxy-2-substituted fortimicin A and B and derivatives |
US4282211A (en) * | 1979-09-26 | 1981-08-04 | Abbott Laboratories | 1-Epi-2-deoxyfortimicin B and derivatives |
US4263429A (en) * | 1979-09-26 | 1981-04-21 | Abbott Laboratories | 1,2,6-Tri-N-benzyloxycarbonylfortimicin B-4,5-carbamate and 1,2,6-tri-N-acetylfortimicin B-4,5-carbamate |
US4252972A (en) * | 1979-09-26 | 1981-02-24 | Abbott Laboratories | Fortimicin B-1,2:4,5-bis-carbamates |
US4360667A (en) * | 1979-11-06 | 1982-11-23 | Abbott Laboratories | (1,2',6'-Tri-N-(2-O-methanesulfonylsalicylidine)-4,5-(2-O-methanesulfonylsalicylaldehyde) oxazolidine-2-O-methanesulfonylfortimicin B |
US4283529A (en) * | 1980-03-03 | 1981-08-11 | Abbott Laboratories | 3-O-Demethyl derivatives of Sannamycin C and antibiotic AX-127B-1 |
EP0044477B1 (fr) * | 1980-07-15 | 1984-02-08 | Kowa Company, Ltd. | Procédé de préparation d'antibiotiques et antibiotiques ainsi obtenus |
JPS58198497A (ja) * | 1982-05-14 | 1983-11-18 | Kowa Co | 新規アミノ配糖体及びその製法 |
US7794713B2 (en) | 2004-04-07 | 2010-09-14 | Lpath, Inc. | Compositions and methods for the treatment and prevention of hyperproliferative diseases |
US7862812B2 (en) | 2006-05-31 | 2011-01-04 | Lpath, Inc. | Methods for decreasing immune response and treating immune conditions |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3931400A (en) * | 1973-04-17 | 1976-01-06 | Abbott Laboratories | Fortimicin B and process for production thereof |
JPS5145675B2 (fr) * | 1973-07-23 | 1976-12-04 |
-
1977
- 1977-12-21 US US05/863,011 patent/US4176178A/en not_active Expired - Lifetime
-
1978
- 1978-10-24 CA CA314,077A patent/CA1126741A/fr not_active Expired
- 1978-10-31 AU AU41196/78A patent/AU521682B2/en not_active Expired
- 1978-11-28 GR GR57747A patent/GR65686B/el unknown
- 1978-12-06 PH PH21897A patent/PH16247A/en unknown
- 1978-12-08 JP JP15120278A patent/JPS5488245A/ja active Pending
- 1978-12-13 SE SE7812828A patent/SE7812828L/xx unknown
- 1978-12-20 DE DE19782855094 patent/DE2855094A1/de not_active Withdrawn
- 1978-12-20 GB GB7849398A patent/GB2010823B/en not_active Expired
- 1978-12-21 FR FR7836002A patent/FR2412565A1/fr active Granted
Non-Patent Citations (1)
Title |
---|
EXBK/77 * |
Also Published As
Publication number | Publication date |
---|---|
US4176178A (en) | 1979-11-27 |
DE2855094A1 (de) | 1979-07-05 |
AU521682B2 (en) | 1982-04-22 |
SE7812828L (sv) | 1979-06-22 |
JPS5488245A (en) | 1979-07-13 |
GB2010823A (en) | 1979-07-04 |
GR65686B (en) | 1980-10-18 |
FR2412565B1 (fr) | 1982-07-09 |
AU4119678A (en) | 1980-05-08 |
PH16247A (en) | 1983-08-16 |
GB2010823B (en) | 1982-12-08 |
CA1126741A (fr) | 1982-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |