FR2456106A1 - Procede de preparation d'exahydro-pyrimido-(1,2-a) azepines 3-substituees et compositions pharmaceutiques qui les contiennent et nouvelles hexahydropyrimido (1,2-a) azepines 3-substituees - Google Patents
Procede de preparation d'exahydro-pyrimido-(1,2-a) azepines 3-substituees et compositions pharmaceutiques qui les contiennent et nouvelles hexahydropyrimido (1,2-a) azepines 3-substitueesInfo
- Publication number
- FR2456106A1 FR2456106A1 FR8010479A FR8010479A FR2456106A1 FR 2456106 A1 FR2456106 A1 FR 2456106A1 FR 8010479 A FR8010479 A FR 8010479A FR 8010479 A FR8010479 A FR 8010479A FR 2456106 A1 FR2456106 A1 FR 2456106A1
- Authority
- FR
- France
- Prior art keywords
- substituted
- pyrimido
- hexahydropyrimido
- exahydro
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- KKFDJZZADQONDE-UHFFFAOYSA-N (hydridonitrato)hydroxidocarbon(.) Chemical class O[C]=N KKFDJZZADQONDE-UHFFFAOYSA-N 0.000 abstract 1
- -1 CARBOXYL Chemical class 0.000 abstract 1
- OCBFFGCSTGGPSQ-UHFFFAOYSA-N [CH2]CC Chemical class [CH2]CC OCBFFGCSTGGPSQ-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001538 azepines Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'INVENTION CONCERNE DES DERIVES DE PYRIMIDO 1,2-A AZEPINE DE FORMULE GENERALE I: (CF DESSIN DANS BOPI) ET (CF DESSIN DANS BOPI) ET LEURS MELANGES, AINSI QUE LEURS SELS D'ADDITION ACIDES ET SELS QUATERNAIRES PHARMACEUTIQUEMENT ACCEPTABLES;OUR REPRESENTE UN HYDROGENE OU UN ALCOYLE INFERIEUR;R REPRESENTE UN ALCOYLE INFERIEUR, UN PHENYLE, UN CARBOXYLE, UN ALCOXYCARBONYLE INFERIEUR, UN NITRILE, UN CARBAMOYLE OU UN CARBOHYDRAZIDO;R REPRESENTE UN HYDROGENE OU UN ALCOYLE INFERIEUR, AVEC LA PRECISION QUE SI DANS LA FORMULE GENERALEI, R REPRESENTE UN HYDROGENE, ALORS R NE PEUT REPRESENTER NI UN NITRILE, NI UN ALCOXYCARBONYLE NI UN PROPYLE, QUI SONT DES COMPOSES UTILES COMME MEDICAMENTS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU79CI1931A HU177184B (en) | 1979-05-11 | 1979-05-11 | Process for producing 2,3- and 3,4-disubstituted-hexahydro-pyrimido-square bracket-1,2-a-square bracket closed-asepines |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2456106A1 true FR2456106A1 (fr) | 1980-12-05 |
FR2456106B1 FR2456106B1 (fr) | 1984-01-20 |
Family
ID=10994746
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8010479A Granted FR2456106A1 (fr) | 1979-05-11 | 1980-05-09 | Procede de preparation d'exahydro-pyrimido-(1,2-a) azepines 3-substituees et compositions pharmaceutiques qui les contiennent et nouvelles hexahydropyrimido (1,2-a) azepines 3-substituees |
FR8107052A Granted FR2480602A1 (fr) | 1979-05-11 | 1981-04-08 | Hexahydro-pyrimido(1,2-a)azepines 3-substituees a titre de medicaments |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8107052A Granted FR2480602A1 (fr) | 1979-05-11 | 1981-04-08 | Hexahydro-pyrimido(1,2-a)azepines 3-substituees a titre de medicaments |
Country Status (27)
Country | Link |
---|---|
US (1) | US4404205A (fr) |
JP (1) | JPS5618984A (fr) |
AR (1) | AR228136A1 (fr) |
AT (1) | AT390615B (fr) |
AU (1) | AU541505B2 (fr) |
BE (1) | BE883216A (fr) |
CA (1) | CA1143729A (fr) |
CH (1) | CH649552A5 (fr) |
CS (1) | CS216529B2 (fr) |
DD (1) | DD150611A5 (fr) |
DE (1) | DE3017565A1 (fr) |
DK (1) | DK152500C (fr) |
ES (1) | ES491360A0 (fr) |
FI (1) | FI70217C (fr) |
FR (2) | FR2456106A1 (fr) |
GB (1) | GB2051047B (fr) |
GR (1) | GR68520B (fr) |
HU (1) | HU177184B (fr) |
IL (1) | IL60026A (fr) |
IT (1) | IT1147733B (fr) |
LU (1) | LU82436A1 (fr) |
NL (1) | NL8002683A (fr) |
NO (1) | NO154427C (fr) |
PL (1) | PL123691B1 (fr) |
PT (1) | PT71212A (fr) |
SE (1) | SE436883B (fr) |
SU (1) | SU981319A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU191192B (en) * | 1982-11-16 | 1987-01-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu | Process for producing new azepino /1,2-a/ pyrimidine derivatives of bronchodilating activity and acid additional salts thereof and pharmaceiutical compositions containing them |
US11681227B2 (en) * | 2019-02-25 | 2023-06-20 | Alex P. G. Robinson | Enhanced EUV photoresist materials, formulations and processes |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2154482A1 (fr) * | 1971-09-10 | 1973-05-11 | Takeda Chemical Industries Ltd |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE451733C (de) | 1923-07-21 | 1927-11-03 | A E Tschitschibabin Dr | Verfahren zur Darstellung von dicyklischen und polycyklischen Verbindungen, die hydrierte oder nichthydrierte Imidazol- oder Pyrimidinkerne enthalten |
US3002000A (en) * | 1958-11-08 | 1961-09-26 | Bayer Ag | 1,2-alkylene-dihydropyrimidone-6, and 1,2-alkylene-imidazolinones-(5) |
CH538494A (de) * | 1966-11-02 | 1973-06-30 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur Herstellung neuer Homopyrimidazol-Derivate |
HU167676B (fr) * | 1972-11-29 | 1975-11-28 |
-
1979
- 1979-05-11 HU HU79CI1931A patent/HU177184B/hu not_active IP Right Cessation
-
1980
- 1980-05-03 GR GR61854A patent/GR68520B/el unknown
- 1980-05-08 DE DE19803017565 patent/DE3017565A1/de not_active Withdrawn
- 1980-05-08 SE SE8003478A patent/SE436883B/sv not_active IP Right Cessation
- 1980-05-08 SU SU802921150A patent/SU981319A1/ru active
- 1980-05-08 IL IL60026A patent/IL60026A/xx unknown
- 1980-05-08 CS CS803260A patent/CS216529B2/cs unknown
- 1980-05-09 IT IT67722/80A patent/IT1147733B/it active
- 1980-05-09 NO NO801377A patent/NO154427C/no unknown
- 1980-05-09 AT AT0247380A patent/AT390615B/de not_active IP Right Cessation
- 1980-05-09 CH CH3662/80A patent/CH649552A5/de not_active IP Right Cessation
- 1980-05-09 DK DK204780A patent/DK152500C/da not_active IP Right Cessation
- 1980-05-09 PT PT71212A patent/PT71212A/pt unknown
- 1980-05-09 BE BE0/200549A patent/BE883216A/fr not_active IP Right Cessation
- 1980-05-09 CA CA000351665A patent/CA1143729A/fr not_active Expired
- 1980-05-09 AU AU58277/80A patent/AU541505B2/en not_active Ceased
- 1980-05-09 JP JP6161580A patent/JPS5618984A/ja active Pending
- 1980-05-09 ES ES491360A patent/ES491360A0/es active Granted
- 1980-05-09 AR AR280968A patent/AR228136A1/es active
- 1980-05-09 US US06/148,234 patent/US4404205A/en not_active Expired - Lifetime
- 1980-05-09 DD DD80220985A patent/DD150611A5/de not_active IP Right Cessation
- 1980-05-09 NL NL8002683A patent/NL8002683A/nl not_active Application Discontinuation
- 1980-05-09 FR FR8010479A patent/FR2456106A1/fr active Granted
- 1980-05-09 GB GB8015418A patent/GB2051047B/en not_active Expired
- 1980-05-09 FI FI801514A patent/FI70217C/fi not_active IP Right Cessation
- 1980-05-09 LU LU82436A patent/LU82436A1/de unknown
- 1980-05-10 PL PL1980224165A patent/PL123691B1/pl unknown
-
1981
- 1981-04-08 FR FR8107052A patent/FR2480602A1/fr active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2154482A1 (fr) * | 1971-09-10 | 1973-05-11 | Takeda Chemical Industries Ltd |
Non-Patent Citations (2)
Title |
---|
CHEMICAL ABSTRACTS, vol.84, 1976, page 504, résumé no.41123f, Columbus, Ohio (US) & HU - A - 10 021 (CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT.) (28 juin 1975) * |
CHEMICAL ABSTRACTS, vol.94, no.1, 5 janvier 1981, page 372, résumé no.3977a, Columbus, Ohio (US) * |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |